Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 87, Issue 11, 2016, Pages 1268-1270

  Zhang, Ming ^a   Xi, Zhengrui ^a   Ghani, Mahdi ^a   Jia, Peixin ^b   Pal, Mrinal ^b   Werynska, Karolina ^a   Moreno, Danielle ^a   Sato, Christine ^a   Liang, Yan ^a   Robertson, Janice ^a   Petronis, Arturas ^b   Zinman, Lorne ^c,d   Rogaeva, Ekaterina ^a,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

ALS; GENETICS

Indexed keywords

ADULT; AGE; AMYOTROPHIC LATERAL SCLEROSIS; ARHGEF28 GENE; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; LETTER; MIDDLE AGED; MONOZYGOTIC TWINS; MORTALITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PYROSEQUENCING; SOD1 GENE; TWIN DISCORDANCE; CANADA; ETHNOLOGY; GENETICS; ITALY; MUTATION; TWINS;

ARHGEF3 PROTEIN, HUMAN; COPPER ZINC SUPEROXIDE DISMUTASE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; SOD1 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; CANADA; DNA METHYLATION; HUMANS; ITALY; MIDDLE AGED; MUTATION; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SUPEROXIDE DISMUTASE-1; TWINS, MONOZYGOTIC;

EID: 84966628710     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2016-313592     Document Type: Letter

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