Fatal Primaquine-Induced Hemolysis in a Patient with Plasmodium vivax Malaria and G6PD A(-) Variant in the Brazilian Amazon

Clinical Infectious Diseases

Volumn 62, Issue 9, 2016, Pages 1188-

  Monteiro, Wuelton M ^a,b   Moura Neto, Jose P ^c   Recht, Judith ^e   Bassat, Quique ^f,g   Lacerda, Marcus V G ^a,d  

^a FUNDAÇÃO DE MEDICINA TROPICAL DR HEITOR VIEIRA DOURADO   (Brazil)

^b UNIVERSIDADE DO ESTADO DO AMAZONAS   (Brazil)

^c FEDERAL UNIVERSITY OF AMAZONAS   (Brazil)

^d INSTITUTO LEÔNIDAS E MARIA DEANE   (Brazil)

^e Universitat de Barcelona ^*  (Brazil)

^f CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^g Manhiça Health Research Center   (Mozambique)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; PRIMAQUINE; ANTIMALARIAL AGENT; GLUCOSE-6-PHOSPHATE DEHYDROGENASE A-;

ACUTE KIDNEY FAILURE; ADULT; ALCOHOLIC FATTY LIVER; ANEMIA; BORDERLINE STATE; CASE REPORT; DISEASE SEVERITY; ENDEMIC DISEASE; EXON; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEMOLYSIS; HUMAN; INCIDENTAL FINDING; LETTER; MALE; MIDDLE AGED; PLASMODIUM VIVAX MALARIA; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; RESPIRATORY DISTRESS; YOUNG ADULT; BRAZIL; CHEMICALLY INDUCED; FATALITY; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; MALARIA, VIVAX; METABOLISM; X CHROMOSOME LINKED DISORDER;

ANTIMALARIALS; BRAZIL; FATAL OUTCOME; GENETIC DISEASES, X-LINKED; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HUMANS; MALARIA, VIVAX; MALE; MIDDLE AGED; PRIMAQUINE;

EID: 84966551162     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciw039     Document Type: Letter

References (6)

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2. Recht J, Ashley EA, White N. Safety of 8-aminoquinoline antimalarial medicines. Geneva, Switzerland: World Health Organization, 2014.
3. Howes RE, Piel FB, Patil AP, et al. G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map. PLoS Med 2012; 9: e1001339.
4. Howes RE, Dewi M, Piel FB, et al. Spatial distribution of G6PD deficiency variants across malaria-endemic regions. Malar J 2013; 12:418.
5. Monteiro WM, Franca GP, Melo GC, et al. Clinical complications of G6PD deficiency in Latin American and Caribbean populations: systematic review and implications for malaria elimination programmes. Malar J 2014; 13:70.
6. Pamba A, Richardson ND, Carter N, et al. Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase-deficient children receiving dapsone. Blood 2012; 120:4123-33.