Automated synthesis of [18F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models

EJNMMI Research

Volumn 6, Issue 1, 2016, Pages

  Bouvet, Vincent ^a   Wuest, Melinda ^a   Jans, Hans Soenke ^a   Janzen, Nancy ^b   Genady, Afaf R ^b   Valliant, John F ^b   Benard, Francois ^c   Wuest, Frank ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

18FDCFPyL; Automated radiosynthesis; Positron emission tomography (PET); Prostate cancer; Prostate specific membrane antigen (PSMA)

Indexed keywords

(S) 2 [3 ((S) 1 CARBOXY 5 [3 (6 FLUOROPYRIDINE)CARBONYL)AMINO)PENTYL)UREIDO] PENTANEDIOIC ACID; (S) 2 [3 ((S) 1 TERT. BUTYLCARBOXYLATE (5 BENZYLOXYCARBONYLPENTYL))UREIDO] DI TERT. BUTYL PENTANEDIOATE; (S) 2 [3 ((S) 5 AMINO 1 TERT. BUTOXYCARBONYLPENTYL)UREIDO]PENTANEDIOIC ACID DI TERT. BUTYL ESTER; (S) DI TERT. BUTYL (((2,5 DIOXOPYRROLIDIN 1 YL)OXY)CARBONYL) L GLUTAMATE; 6 TRIMETHYLAMMONIUM NICOTINIC ACID 2,3,5,6 TETRAFLUOROPHENYL ESTER TRIFLATE; FLUORINE 18; PROSTATE SPECIFIC MEMBRANE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOACTIVITY; RADIOFLUORINATION; TUMOR VOLUME;

EID: 84966440560     PISSN: None     EISSN: 2191219X     Source Type: Journal    
DOI: 10.1186/s13550-016-0195-6     Document Type: Article

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