Protective effect of curcumin on priapism and ischemia-reperfusion injury in rats

European Review for Medical and Pharmacological Sciences

Volumn 19, Issue 23, 2015, Pages 4664-4670

  Yilmaz, Y ^a   Taken, K ^b   Atar, M ^a   Ergun M ^c   Soylemez H ^a  

^a DICLE UNIVERSITY   (Turkey)

^b YUZUNCU YIL UNIVERSITY   (Turkey)

^c Mus State Hospital   (Turkey)

Author keywords

Curcumin; Oxidative stress; Paraoxonase; Priapism; Rats

Indexed keywords

AGENTS ACTING ON THE GENITAL SYSTEM; ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE 1; CURCUMIN; ARYLDIALKYLPHOSPHATASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; EDEMA; EXPERIMENTAL STUDY; HISTOPATHOLOGY; INFERIOR CAVA VEIN; MALE; NONHUMAN; OXIDATIVE STRESS; PENILE BLEEDING; PENILE NECROSIS; PENILE SWELLING; PENIS AMPUTATION; PENIS INJURY; PRIAPISM; RAT; REPERFUSION INJURY; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE; ANIMAL; DRUG EFFECTS; METABOLISM; PATHOLOGY; PENIS; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; ARYLDIALKYLPHOSPHATASE; CURCUMIN; MALE; OXIDATIVE STRESS; PENIS; PRIAPISM; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 84966359464     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. BRODERICK GA, KADIOLU A, BIVAILACQUA TJ, GHANEM H, NEHRA A, SHAMLOUL R. Priapism: pathogenesis, epidemiology, and management. J Sex Med 2010; 7: 476-500.
2. AVISRROR MU, FERNANDEZ IA, SANCHEZ AS, GARCIAPANDO AC, ARIAS LM, DEL POZO JG. Doxazosin and priapism. J Urol 2000; 163: 238.
3. KHALIL AA, AZIZ FA, HALL JC. Reperfusion injury. Plast Reconstr Surg 2006; 117: 1024-1033.
4. HALLIWELL B. Reactive species and antioxidants: Redox biology is a fundamental theme of aerobic life. Plant Physiol 2006; 141: 312-322.
5. THIYAGARAJAN M, SHARMA SS. Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sci 2004; 74: 969-985.
6. OGUZ A, KAPAN M, ONDER A, KILIC E, GUMUS M, BASARALI MK, FIRAT U, BOYUK A, BUYUKBAS S. The effects of curcumin on the liver and remote organs after hepatic ischemia reperfusion injury formed with Pringle manoeuvre in rats. Eur Rev Med Pharmacol Sci 2013; 17: 457-466.
7. EREL O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 2004; 37: 277-85.
8. ECKERSON HW, WYTE CM, LA DU BN. The human serum paraoxonase/arylesterase polymorphism. Am J Hum Genet 1983; 35: 1126-1138.
9. ZIMMERMAN BJ, GRANGER DN. Reperfusion injury. Surg Clin North Am 1992; 72: 65-83.
10. WILHELM J. Metabolic aspects of membrane lipid peroxidation. Acta Univ Carol Med Monogr 1990; 137: 1-53.
11. JENNINGS RB, REIMER KA. The cell biology of acute myocardial ischemia. Annu Rev Med 1991; 42: 225-246.
12. GREEN CJ, GOWER JD, HEALING G, COTTERILL LA, FULLER BJ, SIMPKIN S. The importance of iron, calcium and free radicals in reperfusion injury: an overview of studies in ischaemic rabbit kidneys. Free Radic Res Commun 1989; 7: 255-264.
13. ORRENIUS S, BURKITT MJ, KASS GE, DYPBUKT JM, NICOTERA P. Calcium ions and oxidative cell injury. Ann Neurol 1992; 32: 33-42.
14. MIQUEL J, BERND A, SEMPERE JM, DIAZ-ALPERI J, RAMIREZ A. The curcuma antioxidants: pharmacological effects and prospects for future clinical use. Arch Gerontol Geriatr 2002; 34: 37-46.
15. SREEJAYAN N, RAO MN. Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol 1997; 49: 105-107.
16. SREEJAYAN N, RAO MN. Free radical scavenging activity of curcuminoids. Arzneimittelforschung 1996; 46: 169-171.
17. DICKINSON DA, ILES KE, ZHANG H, BLANK V, FORMAN HJ. Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression. FASEB J 2003; 17: 473-475.
18. ULUOCAK N, ATILGAN D, EREDMIR F, PARLAKTAS BS, YASAR A, ERKORKMAZ U, AKBAS A. An animal model of ischemic priapism and the effects of melatonin on antioxidant enzymes and oxidative injury parameters in rat penis. Int Urol Nephrol 2010; 42: 889-895.
19. SANLI O, ARMAGAN A, KANDIRALI E, OZERMAN B, AHMEDOV I, SOLAKOGLU S, NURTEN A, TUNC M, UYSAL V, KADIOGLU A. TGF-b1 neutralizing antibodies decrease the fibrotic effects of ischemic priapism. Int J Impot Res 2004; 16: 492-497.
20. CHEN KK, CHAN JY, CHANQ LS, CHEN MT, CHAN SH. Intracavernous pressure as an experimental index in a rat model for the evaluation of penile erection. J Urol 1992; 147: 1124-1128.
21. EREL O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem 2004; 37: 112-119.
22. OZACMAK VH, OZACMAK HS. Curcumin reduces oxidative stress in ovariectomized rat brain subjected to chronic cerebral hypoperfusion. Turk J Geriatr 2010; 13: 160-165.
23. ONDER A, KAPAN M, GUMUS M, YUKSEL H, BOYUK A, ALP H, BASARILI MK, FIRAT U. The protective effects of curcumin on intestine and remote organs against mesenteric ischemia/reperfusion injury. Turk J Gastroenterol 2012; 23: 141-147.
24. ACAR A, AKIL E, ALP H, EVLIYAOGLU O, KIBRISLI E, INAL A, UNAN F, TASDEMIR N. Oxidative damage is ameliorated by curcumin treatment in brain and sciatic nerve of diabetic rats. Int J Neurosci 2012; 122: 367-372.
25. TOPSAKAL C, KILIC N, EROL FS, KAPLAN M, AKDEMIR I, TIFTIKCI M, GÜRSU F. Medroxyprogesterone acetate, enoxaparin and pentoxyfylline cause alterations in lipid peroxidation, paraoxonase (PON1) activities and homocysteine levels in the acute oxidative stress in an experimental model of spinal cord injury. Acta Neurochir 2002; 144: 1021-1031.
26. UZAR E, TAMAM Y, EVLIYAOGLU O, TUZCU A, BEYAZ C, ACAR A, AYDIN B, TASDEMIR N. Serum prolidase activity and oxidative status in patients with diabetic neuropathy. Neurol Sci 2012; 33: 875-880.
27. AKPOLAT M, KANTER M, UZAL MC. Protective effects of curcumin against gamma radiation-induced ileal mucosal damage. Arch Toxicol 2009; 83: 609-617.
28. SAVAS M, YENI E, CIFTCI H, YILDIZ F, GULUM M, KESER BS, VERIT A, UTANGAC M, KOCYIGIT A, CELIK H, BITIREN M. The antioxidant role of oral administration of garlic oil on renal ischemia-reperfusion injury. Ren Fail 2010; 32: 362-367.