Exchange transfusion in the treatment of neonatal septic shock: A ten-year experience in a neonatal intensive care unit

International Journal of Molecular Sciences

Volumn 17, Issue 5, 2016, Pages

  Pugni, Lorenza ^a   Ronchi, Andrea ^a   Bizzarri, Bianca ^b   Consonni, Dario ^a   Pietrasanta, Carlo ^a   Ghirardi, Beatrice ^a   Fumagalli, Monica ^a   Ghirardello, Stefano ^a   Mosca, Fabio ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Exchange transfusion; Neonatal infection; Neonatal sepsis; Neonatal septic shock; Neonate; Preterm infant; Therapy of septic shock

Indexed keywords

ADRENALIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; CREATININE; DOBUTAMINE; DOPAMINE; LACTIC ACID; UREA;

APGAR SCORE; ARTERY CATHETER; ARTICLE; BIRTH WEIGHT; BLOOD CULTURE; CANDIDA ALBICANS; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; EXCHANGE BLOOD TRANSFUSION; FEMALE; FEMORAL VEIN; GESTATIONAL AGE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; ICD-9; INTERNAL JUGULAR VEIN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEWBORN; NEWBORN INTENSIVE CARE; OLIGURIA; PREMATURITY; RETROSPECTIVE STUDY; SEPTIC SHOCK; URINE CULTURE; ADVERSE EFFECTS; COMPARATIVE STUDY; EVALUATION STUDY; NEONATAL INTENSIVE CARE UNIT; NEONATAL SEPSIS; PROCEDURES; SHOCK, SEPTIC; STATISTICS AND NUMERICAL DATA;

EXCHANGE TRANSFUSION, WHOLE BLOOD; FEMALE; HUMANS; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; MALE; NEONATAL SEPSIS; SHOCK, SEPTIC;

EID: 84966350590     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17050695     Document Type: Article

References (40)

1. Palazzi, D.B., Klein, J.O., Baker, C.J. Bacterial sepsis and meningitis. In Infectious Diseases of the Fetus and Newborn Infant, 6th ed., Remington, J.S., Klein, J.O., Wilson, C.B., Baker, C.J., Eds., Elsevier Saunders: Philadelphia, PA, USA, 2006, pp. 247–295.
2. Shane, A.L., Stoll, B.J. Neonatal sepsis: Progress towards improved outcomes. J. Infect. 2014, 68, S24–S32. [CrossRef] [PubMed]
3. Klinger, G., Levy, I., Sirota, L., Boyko, V., Lerner-Geva, L., Reichman, B. Israel Neonatal Network. Outcome of early-onset sepsis in a national cohort of very low birth weight infants. Pediatrics 2010, 125, e736–e740. [CrossRef] [PubMed]
4. Stoll, B.J., Hansen, N.I., Adams-Chapman, I., Fanaroff, A.A., Hintz, S.R., Vohr, B., Higgins, R.D. National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental and growth impairment among extremely low-birth weight infants with neonatal infection. JAMA 2004, 292, 2357–2365. [CrossRef] [PubMed]
5. Kermorvant-Duchemin, E., Laborie, S., Rabilloud, M., Lapillonne, A., Claris, O. Outcome and prognostic factors in neonates with septic shock. Pediatr. Crit. Care Med. 2008, 9, 186–191. [CrossRef] [PubMed]
6. Tarnow-Mordi, W., Isaacs, D., Dutta, S. Adjunctive immunologic interventions in neonatal sepsis. Clin. Perinatol. 2010, 37, 481–499. [CrossRef] [PubMed]
7. Ohlsson, A., Lacy, J.B. Intravenous immunoglobulin for suspected or proven infection in neonates. Cochrane Database Syst. Rev. 2013, 7, CD001239. [PubMed]
8. Carr, R., Modi, N., Doré, C. G-CSF and GM-CSF for treating or preventing neonatal infections. Cochrane Database Syst. Rev. 2003, 3, CD003066. [PubMed]
9. Prod’hom, L.S., Choffat, J.M., Frenck, N., Mazoumi, M., Relier, J.P., Torrado, A. Care of seriously ill neonate with hyaline membrane disease and with sepsis (Sclerema neonatorum). Pediatrics 1974, 53, 170–181. [PubMed]
10. Xanthou, M., Xypolyta, A., Anagnostakis, D., Economou-Mavrou, C., Matsaniotis, N. Exchange transfusion in severe neonatal infection with sclerema. Arch. Dis. Child. 1975, 50, 901–902. [CrossRef] [PubMed]
11. Töllner, U., Pohlandt, F., Heinze, F., Henrichs, I. Treatment of septicaemia in the newborn infant: Choice of initial antimicrobial drugs and the role of exchange transfusion. Acta Paediatr. Scand. 1977, 66, 605–610. [CrossRef] [PubMed]
12. Vain, N.E., Mazlumian, J.R., Swarner, O.W., Cha, C.C. Role of exchange transfusion in the treatment of severe septicemia. Pediatrics 1980, 66, 693–697. [PubMed]
13. Lemos, L. Exchange transfusion in treatment of sepsis. Pediatrics 1981, 68, 471–472. [PubMed]
14. Mathur, N.B. Neonatal sepsis. Indian Pediatr. 1996, 33, 663–674. [PubMed]
15. Togari, H., Mikawa, M., Iwanaga, T., Matsumoto, N., Kawase, A., Hagisawa, M., Ogino, T., Goto, R., Watanabe, I., Kito, H., et al. Endotoxin clearance by exchange blood transfusion in septic shock neonates. Acta Paediatr. Scand. 1983, 72, 87–91. [CrossRef] [PubMed]
16. Sadana, S., Mathur, N.B., Thakur, A. Exchange transfusion in septic neonates with sclerema: Effect on immunoglobulin and complement levels. Indian Pediatr. 1997, 34, 20–25. [PubMed]
17. Xanthou, M., Nicolopoulos, D., Gizas, A., Matsaniotis, N. The response of leukocytes in the peripheral blood during and following exchange transfusion in the newborn. Pediatrics 1973, 51, 570–574. [PubMed]
18. Christensen, R.D., Anstall, H.B., Rothstein, G. Use of whole blood exchange transfusion to supply neutrophils to septic, neutropenic neonates. Transfusion 1982, 22, 504–506. [CrossRef] [PubMed]
19. De Curtis, M., Vetrano, G., Romano, G., D’Antonio, F., Paludetto, R., Ciccimarra, F. Improvement of phagocytosis and nitroblue tetrazolium reduction after exchange transfusions in two preterm infants with severe septicemia. Pediatrics 1982, 70, 829–830. [PubMed]
20. Mathur, N.B., Subramanian, B.K., Sharma, V.K., Puri, R.K. Exchange transfusion in neutropenic septicemic neonates: Effect on granulocyte functions. Acta Paediatr. 1993, 82, 939–943. [CrossRef] [PubMed]
21. Bossi, E., Meister, B., Pfenninger, J. Exchange transfusion for severe neonatal septicemia. Pediatrics 1981, 67, 941. [PubMed]
22. Narayanan, I., Mitter, A., Gujral, V.V. A comparative study on the value of exchange and blood transfusion in the management of severe neonatal septicemia with sclerema. Indian J. Pediatr. 1982, 49, 519–523. [CrossRef] [PubMed]
23. Dalvi, R., Rao, S., Rangnekar, J., Fernandez, A. Exchange transfusions in neonatal sepsis. Indian Pediatr. 1991, 28, 39–43. [PubMed]
24. Gunes, T., Koklu, E., Buyukkayhan, D., Kurtoglu, S., Karakukcu, M., Patiroglu, T. Exchange transfusion or intravenous immunoglobulin therapy as an adjunct to antibiotics for neonatal sepsis in developing countries: A pilot study. Ann. Trop. Paediatr. 2006, 26, 39–42. [CrossRef] [PubMed]
25. Aradhya, A.S., Sundaram, V., Kumar, P., Ganapathy, S.M., Jain, A., Rawat, A. Double Volume Exchange Transfusion in Severe Neonatal Sepsis. Indian J. Pediatr. 2016, 83, 107–113. [CrossRef] [PubMed]
26. Gross, S.J., Filston, H.C., Anderson, J.C. Controlled study of treatment for disseminated intravascular coagulation in the neonate. J. Pediatr. 1982, 100, 445–448. [CrossRef]
27. Phibbs, R.H. Response of newborn infants to leukocyte depletion during exchange transfusions. Biol. Neonate 1970, 15, 112–122. [CrossRef] [PubMed]
28. Levinson, S.A., Hume, D.M. Effect of exchange transfusion with fresh whole blood on refractory septic shock. Am. Surg. 1972, 38, 49–55. [PubMed]
29. Stoll, B.J., Hansen, N., Fanaroff, A.A., Wright, L.L., Carlo, W.A., Ehrenkranz, R.A., Lemons, J.A., Donovan, E.F., Stark, A.R., Tyson, J.E., et al. Late-onset sepsis in very low birth weight neonates: The experience of the NICHD Neonatal Research Network. Pediatrics 2002, 110, 285–291. [CrossRef] [PubMed]
30. Sarkar, S., Bhagat, I., Hieber, S., Donn, S.M. Can neutrophil responses in very low birth weight infants predict the organisms responsible for late-onset bacterial or fungal sepsis? J. Perinatol. 2006, 26, 501–505. [CrossRef] [PubMed]
31. Steiner, L.A., Bizzarro, M.J., Ehrenkranz, R.A., Gallagher, P.G. A decline in the frequency of neonatal exchange transfusions and its effect on exchange-related morbidity and mortality. Pediatrics 2007, 120, 27–32. [CrossRef] [PubMed]
32. Goldstein, B., Giroir, B., Randolph, A. International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr. Crit. Care Med. 2005, 6, 2–8. [CrossRef] [PubMed]
33. Wynn, J.L., Wong, H.R. Pathophysiology and treatment of septic shock in neonates. Clin. Perinatol. 2010, 37, 439–479. [CrossRef] [PubMed]
34. Bertino, E., Spada, E., Occhi, L., Coscia, A., Giuliani, F., Gagliardi, L., Gilli, G., Bona, G., Fabris, C., de Curtis, M., et al. Neonatal anthropometric charts: The Italian neonatal study compared with other European studies. J. Pediatr. Gastroenterol. Nutr. 2010, 51, 353–361. [CrossRef] [PubMed]
35. Moore, T.A., Wilson, M.E. Feeding intolerance: A concept analysis. Adv. Neonatal. Care 2011, 11, 149–154. [CrossRef] [PubMed]
36. Papile, L.A., Burstein, J., Burstein, R., Koffler, H. Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1500 gm. J. Pediatr. 1978, 92, 529–534. [CrossRef]
37. Richardson, D.K., Corcoran, J.D., Escobar, G.J., Lee, S.K. SNAP-II and SNAPPE-II: Simplified newborn illness severity and mortality risk scores. J. Pediatr. 2001, 138, 92–100. [CrossRef] [PubMed]
38. Levit, O., Bhandari, V., Li, F.Y., Shabanova, V., Gallagher, P.G., Bizzarro, M.J. Clinical and laboratory factors that predict death in very low birth weight infants presenting with late-onset sepsis. Pediatr. Infect. Dis. J. 2014, 33, 143–146. [CrossRef] [PubMed]
39. Pugni, L., Riva, E., Pietrasanta, C., Rabacchi, C., Bertolini, S., Pederiva, C., Mosca, F., Calandra, S. Severe hypertriglyceridemia in a newborn with monogenic lipoprotein lipase deficiency: An unconventional therapeutic approach with exchange transfusion. JIMD Rep. 2014, 13, 59–64. [PubMed]
40. Murki, S., Kumar, P. Blood exchange transfusion for infants with severe neonatal hyperbilirubinemia. Semin. Perinatol. 2011, 35, 175–184. [CrossRef] [PubMed]