Responses of retinal and choroidal vessels to ionising radiation

Eye (Basingstoke)

Volumn 7, Issue 1, 1993, Pages 1-13

  Archer, D B ^b  

^a Eye and Ear Clinic Royal Victoria Hospital ^*  (Ireland)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTIMETABOLITE; VINCA ALKALOID;

CELL KINETICS; CHOROID VASCULARIZATION; DIABETES MELLITUS; DISEASE COURSE; DISEASE SEVERITY; HISTOPATHOLOGY; IONIZING RADIATION; LATENT PERIOD; RADIATION DOSE; RADIATION INJURY; RETINA BLOOD VESSEL; RETINOPATHY; REVIEW; RISK FACTOR; TISSUE CULTURE; ULTRASTRUCTURE;

EID: 84966190525     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.1993.3     Document Type: Article

References (125)

1. Chalupecky H. Über die Wirkung der Röentgenstrahlen auf das Auge und die Haut. Zentralbl Prakt Augenheilk 1897;21:234-9.
2. Birch-Hirschfeld GVA. Zur Wirkung der Röentgenstrahlen auf das menschliche Auge. Klin Monatsbl Augenheilkd 1908;46: 129.
3. Rohrschneider W. Experimentelle Untersuchungen über die Veränderungen normaler Augengewebe nach Röent-genbestrahlung. III. Veränderungen der Linse der Netzhaut und des Sehnerven nach Röentgenbehstrahlung. Albrecht von Graefes Arch Klin Exp Ophthalmol 1929; 122;282-90.
4. Stallard HB. Radiant energy as (a) a pathogenic (b) a therapeutic agent in ophthalmic disorders. Br J Ophthalmol Monograph Suppl 1933;6:1-126.
5. Stallard Hb. Glioma retinae treated by radon seeds. BMJ 1936;2:962-4.
6. Moore FR. Reports: 1. Presidential address. The value of radium in intraocular lesions. Trans Ophthalmol Soc UK 1935;55:3-26.
7. Martin H, Reece AB. Treatment of bilateral retinoblastoma (retinal glioma) surgically and by irradiation. Arch Ophthalmol 1945;33:429-39.
8. Pillat A. Fall seltener Röntgenschädigung am Hinderen Augenpol. Klin Monatsbl Augenheilkd 1935;94:384.
9. Stallard HB. Radiotherapy of malignant intraocular neoplasms. Br J Ophthalmol 1948;32:618-39.
10. Stallard HB. Malignant melanoma of the choroid treated with radioactive applicators. Trans Ophthalmol Soc UK 1959;79:373-92.
11. Stallard HB. The conservative treatment of retinoblastoma. Trans Ophthalmol Soc UK 1962; 82:473-534.
12. Stallard HB. Radiotherapy for malignant melanoma of the choroid. Br J Ophthalmol 1966;50:147-55.
13. Howard GM. Ocular effects of radiation and photocoagulation. Arch Ophthalmol 1966;76:7-10.
14. Bedford MA, Bedotto C, MacFaul PA Radiation retinopathy after the application of a cobalt plaque. Br J Ophthalmol 1970;54:505-9.
15. 106Rh beta-ray applicators. Surv Ophthalmol 1974; 19:85-100.
16. Lommatzsch PK. Experiences in the treatment of malignant melanoma of the choroid with ^Ru/^Rh beta-ray applicators. Trans Ophthalmol Soc UK 1973;93:119-32.
17. Lommatzsch PK. ß-Irradiation of choroidal melanoma with i06Ru/'°6Rh applicators. Arch Ophthalmol 1983; 101: 713-7.
18. Lommatzsch PK. Results after ß-irradiation (^Ru/^Rh) of choroidal melanomas: 20 years’ experience. Br J Ophthalmol 1986;70:844-51.
19. Char DH, Lonn LI, Margolis LW. Complications of cobalt plaque therapy of choroidal melanomas. Am J Ophthalmol 1977;84:536-41.
20. Char DH. The management of small choroidal melanomas. Surv Ophthalmol 1978; 22:377-86.
21. Ellsworth RM. Retinoblastoma. Mod Probl Ophthalmol 1977; 18:94-100.
22. Egbert PR, Donaldson SS, Moazed K, Rosenthal AR. Visual results and ocular complications following radiotherapy for retinoblastoma. Arch Ophthalmol 1978;96: 1826-30.
23. Egbert PR, Fajardo LF, Donaldson SS, Moazed K. Posterior ocular abnormalities after irradiation for retinoblastoma: a histopathological study. Br J Ophthalmol 1980;64:660-5.
24. Cruess AF, Augsburger JJ, Shields JA, Donoso LA, Amsel J. Visual results following cobalt plaque radiotherapy for posterior uveal melanomas. Ophthalmology 1984;91: 131-6.
25. Rotman M, Long RS, Packer S, Moroson H, Galin MA, Chan B. Radiation therapy of choroidal melanoma. Trans Ophthalmol Soc UK 1977;97:431-5.
26. Shields JA, Augsburger JJ, Brady LW, Day JL. Cobalt plaque therapy of posterior uveal melanomas. Ophthalmology 1982;89:1201-7.
27. Brown GC, Shields JA, Sanborn G, Augsburger JJ, Savino PJ, Schatz NJ. Radiation retinopathy. Ophthalmology 1982;89: 1494-501.
28. Hayreh SS. Post-radiation retinopathy: a fluorescence fundus angiographic study. Br J Ophthalmol 1970;54:705-14.
29. Tarkkanen A, Laatikainen L. Fluorescein angiography in the long-term follow-up of choroidal melanoma after conservative treatment. Acta Ophthalmol (Copenh) 1985;63: 73-9.
30. Elmassri A. Radiation chorioretinopathy. Br J Ophthalmol 1986;70:326-9.
31. Rh plaque therapy. Retina 1987;7:148-55.
32. Ehlers N, Kaae S. Effects of ionizing radiation on retinoblastoma and on the normal ocular fundus in infants: a photographic and fluorescein angiographic study. Acta Ophthalmol (Copenh) 1987;65(Suppl 181):1-84.
33. Perrers-Taylor M, Brinkley D, Reynolds T. Choroido-ret-inal damage as a complication ofradiotherapy. Acta Radiol Ther Phys Biol 1965;3:431-40.
34. Chee PHY. Radiation retinopathy. Am J Ophthalmol 1968; 66:860-5.
35. Gass JDM. A fluorescein angiographic study of macular dysfunction secondary to retinal vascular disease. VI. X-ray irradiation, carotid artery occlusion, collagen vascular disease and vitritis. Arch Ophthalmol 1968;80: 606-17.
36. De Schryver A, Wachtmeister L, Bäryd I. Ophthalmo-logical observations on long-term survivors after radiotherapy for nasopharyngeal tumours. Acta Radiol Ther Phys Biol 1971;10:193-209.
37. Shukovsky LJ, Fletcher GH. Retinal and optic nerve complications in a high dose irradiation technique of ethmoid sinus and nasal cavity. Radiology 1972;104:629-34.
38. Wara WH, Irvine AR, Neger RE, Howes EL, Phillips TL. Radiation retinopathy. Int J Radiat Oncol Biol Phys 1979; 5:81-4.
39. Bagan SM, Hollenhorst RW. Radiation retinopathy after irradiation of intracranial lesions. Am J Ophthalmol 1979; 88:694-7.
40. Morita K, Kawabe Y. Late effects on the eye of conformation radiotherapy for carcinoma of the paranasal sinuses and nasal cavity. Radiology 1979;130:227-32.
41. Tomsak RL, Smith JL. Radiation retinopathy in a patient with lung carcinoma metastatic to brain. Ann Ophthalmol 1980;12:619-22.
42. Thompson GM, Migdal CS, Whittle RJM. Radiation retinopathy following treatment of posterior nasal space carcinoma. Br J Ophthalmol 1983;67:609-14.
43. Kinyoun JL, Kalina RE, Brower SA, Mills RP, Johnson RH. Radiation retinopathy after orbital irradiation for Graves’ ophthalmopathy. Arch Ophthalmol 1984; 102: 1473-6.
44. Amoaku WMK, Archer DB. Cephalic radiation and retinal vasculopathy. Eye 1990;4: 195-203.
45. Amoaku WMK, Archer DB. Fluorescein angiographic features, natural course and treatment of radiation retinopathy. Eye 1990;4:657-67.
46. Noble KG, Kupersmith MJ. Retinal vascular remodelling in radiation retinopathy. Br J Ophthalmol 1984;68:475-8.
47. Albert DM, Walton DS, Weichselbaum RR, Cassady JR, Little JB, Leumbruno D, et al. Fibroblast radiosensitivity and intraocular fibroblastic proliferation following radiotherapy for bilateral retinoblastoma. Br J Ophthalmol 1986;70:336-42.
48. Archer DB, Amoaku WMK, Kelly G. Choroidoretinal neo-vascularisation following radon seed treatment of retinoblastoma in two patients. Br J Ophthalmol 1993;77:95-9.
49. Boozalis GT, Schachat AP, Green WR. Subretinal neovascularization from the retina in radiation retinopathy. Retina 1987;7:156-61.
50. Kinyoun JL, Chittum ME, Wells CG. Photocoagulation treatment of radiation retinopathy. Am J Ophthalmol 1988; 105:470-8.
51. Axer-Siegel R, Kremer I, Ben-Sira I, Weiss J. Radiation retinopathy treated with the krypton red laser. Ann Ophthalmol 1989;21:272-4.
52. Chaudhuri PR, Austin DJ, Rosenthal AR. Treatment of radiation retinopathy. Br J Ophthalmol 1981;65:623-5.
53. Parson JT, Fitzgerald CR, Hood CI, Ellingwood KE, Bova FJ, Million RR. The effects of irradiation on the eye and optic nerve. Int J Radiat Oncol Biol Phys 1983;9:609-22.
54. Monge OR, Flage T, Hatlevoll R, Vermund H. Sight saving therapy in retinoblastoma: experience with external megavoltage therapy. Acta Ophthalmol (Copenh) 1986;64: 414-20.
55. Buzney SM, Pruett RC, Regan CDJ, Walton DS, Smith TR. Scleral buckling for retinal detachment in patients with retinoblastoma. Am J Ophthalmol 1984;98:473-7.
56. MacFaul PA, Bedford MA. Ocular complications after therapeutic irradiation. Br J Ophthalmol 1970;54:237-47.
57. MacFaul PA. Local radiotherapy in the treatment of malignant melanoma of the choroid. Trans Ophthalmol Soc UK 1977;97:421-7.
58. Bedford MA. The use and abuse of cobalt plaques in the treatment of choroidal malignant melanomata. Trans Ophthalmol Soc UK 1973;93:139-43.
59. 106Rh-applikatoren. Fortschr Ophthalmol 1983;80:418-21.
60. Packer S. lodine-125 radiation of posterior uveal melanoma. Ophthalmology 1987;94:1621-6.
61. Char DH, Castro JR, Kroll SM, Irvine AR, Quivey JM, Stone RD. Five-year follow-up of helium ion therapy for uveal melanoma. Arch Ophthalmol 1990; 108:209-14.
62. Merriam GR, Szechter A, Focht EF. The effects of ionizing radiations on the eye. Front Radiat Ther Oncol 1972;6: 346-85.
63. Nakissa N, Rubin P, Strohl R, Keys H. Ocular and orbital complications following radiation therapy of paranasal sinus malignancies and review of the literature. Cancer 1983;51:980-6.
64. Miller ML, Goldberg SH, Bullock JD. Radiation retinopathy after standard radiotherapy for thyroid-related ophthalmopathy. Am J Ophthalmol 1991;112:600-1.
65. Harris JR, Levene MB. Visual complications following irradiation for pituitary adenomas and craniopharyngiomas. Radiology 1976; 120: 167-71.
66. Aristizabal S, Caldwell WL, Avila J. The relationship of time-dose fractionation factors to complications in the treatment of pituitary tumours by irradiation. Int J Radiat Oncol Biol Phys 1977;2:667-73.
67. Berg NO, Lindgren M. Time-dose relationship and morphology of delayed radiation lesions of the brain in rabbits. Acta Radiol 1958;167(Suppl):l-77.
68. Char DH, Castro JR, Quivey JM, Chen GTY, Lyman JT, Stone RD, et al. Helium ion charged particle therapy for choroidal melanoma. Ophthalmology 1980;87:565-70.
69. Gragoudas ES, Goitein M, Verhey L, Munzenreider J, Suit HD, Koehler A. Proton beam irradiation: an alternative to enucleation for intraocular melanomas. Ophthalmology 1980;87:571-81.
70. Packer S, Rotman M. Radiotherapy of choroidal melanoma with iodine-125. Ophthalmology 1980;87:582-90.
71. Brown N, Roth J, Catterall M, Beal A. Effects of fast neutrons on the eye: a preliminary communication. Br J Ophthalmol 1975;59:510-13.
72. Roth J, Brown N, Catterall M, Beal A. Effects offast neutrons on the eye. Br J Ophthalmol 1976;60;236-44.
73. Bessell EM, Henk JM, Whitelocke RAF, Wright JE. Ocular morbidity after radiotherapy of orbital and conjunctival lymphoma. Eye 1987;1:90-6.
74. Chan RC, Shukovsky LJ. Effects of irradiation on the eye. Radiology 1976; 120:673-6.
75. Chacko DC. Considerations in the diagnosis of radiation injury. JAMA 1981;245:1255-8.
76. Spiel RT. Handbook of cancer chemotherapy. Boston, Mass: Little, Brown, 1976.
77. Portlock CS, Goffrett DR. Manual of clinical problems in oncology. Boston, Mass; Little, Brown, 1986.
78. Griffin JD, Garnick MB. Eye toxicity of cancer chemotherapy: a review of the literature. Cancer 1981; 48: 1539-49.
79. Dhir SP, Joshi AV, Banerjee AK. Radiation retinopathy in diabetes mellitus: report of a case. Acta Radiol Oncol 1982;21:111-3.
80. Brown GC, Shields JA, Sanborn G, Augsburger JJ, Schatz NJ, Savino PJ. Radiation retinopathy. Trans Pa Acad Ophthalmol Otolaryngol 1981;34:144-51.
81. Brown GC, Shields JA, Sanborn G, Augsburger JJ, Savino PJ, Schatz NJ. Radiation optic neuropathy. Ophthalmology 1982;89: 1489-93.
82. Karren KA, Kroll SM, Char DH, Castro JR. Diabetic radiation morbidity. Br J Ophthalmol 1992;76:61-2.
83. Archer DB, Amoaku WMK, Gardiner TA. Radiation retinopathy: clinical, histopathological, ultrastructural and experimental correlations. Eye 1991;5:239-51.
84. McQuaid M, Chakravarthy U, Archer DB. The effects of ionizing radiation on retinal microvascular cell growth in vitro. Doc Ophthalmol 1990;76(2): 105-218.
85. Andrews BS, McIntosh J, Petts V, Penny R. Circulating immune complexes in retinal vasculitis. Clin Exp Immunol 1977;29:23-9.
86. Standford MR. Retinopathy after irradiation and hyperbaric oxygen. J R Soc Med 1984;77:1041-3.
87. Schlaegel TF. Ocular histopathology of some Nagasaki atomic-bomb casualties. AAm J Ophthalmol 1947;30: 127-35.
88. Dhenny P, Coscas G. Retinopathie par radiations et occlu-sionveineuse retienne (aspect histologique). Bull Soc Ophthal (Fr) Paris 1978;78:571-4.
89. Dumoulin-Wibail C, Toussaint D, Dumoulin P. Retinopathie par radiations ionisantes: aspects cliniques. Bull Soc Belge Ophthalmol 1982; 199-200:43-53.
90. Koriyama S, Sakata H, Ogita S. Retinal lesions as a complication of radiotherapy. Jpn J Clin Ophthalmol 1976;30: 69-78.
91. Amoaku WMK. The effects of ionizing radiation on the retina: a clinical and experimental study. Thesis, Doctor of Philosophy, Queen’s University of Belfast, 1990.
92. Cibis PA, Brown DVL. Retinal changes following ionizing radiation. Am J Ophthalmol 1955;40:84-8.
93. Cibis PA, Noell WK, Eichel B. Ocular effects produced by high intensity X-radiation. Arch Ophthalmol 1955;53: 651-63.
94. Brown DVL, Cibis PA, Pickering JE. Radiation studies on the monkey eye. I. Effects of gamma radiation on the retina. Arch Ophthalmol 1955;54:249-56.
95. 60Co irradiation. Am J Ophthalmol 1956;42:309-10.
96. Newell FW, Choi O, Book NA, Harper PU, Simkus A. Focal ionizing radiation of the posterior ocular segment. Am J Ophthalmol 1960;50:1215-25.
97. Devi SK, Riley EF, Bums CA. Electroretinographic responses of the rabbit after X-irradiation. Invest Ophthalmol Vis Sci 1968;7:219-26.
98. Krohn DL, Jacobson JH, Najac HW, Barsa Newton MC, Robertson JS. Toxic effect of thennal neutrons on the rabbit electro-retinogram. Am J Ophthalmol 1970;70:814-21.
99. Bonney CH, Schmidt RE, Hunter DM, Conley GE. Fluorescein angiography and light microscopy studies of retinae irradiated by oxygen nuclei. Aviat Space Environ Med 1977;48:418-23.
100. Gragoudas ES, Zakou NZ, Albert DM, Constable IJ: Long-tenn observations of proton-irradiated monkey eyes. Arch Ophthalmol 1979;97:2184-91.
101. Schmidt RE, Bonney CH. Oxygen nuclei irradiation of retinas: long-tenn observations. Radiat Res 1981; 85: 355-66.
102. Newton JC, Barsa Newton MC, Wisniewski HM, Wen GY. Effects of X-radiation on the retina of the albino rabbit as viewed with the transmission electron microscope. Exp Cell Biol 1984;52:269-78.
103. Ching SV, Gillette SM, Powers BE, Roberts SM, Gilette EL, Withrow SJ. Radiation-induced ocular injury in the dog: a histological study. Int J Radiat Oncol Biol Phys 1990;19:321-8.
104. Irvine AR, Alvarado JA, Wara WM, Morris BW, Wood IS. Radiation retinopathy: an experimental model for the ischaemic-proliferative retinopathies. Trans Am Ophthalmol Soc 1981;79:103-22.
105. Irvine AR, Wood IS. Radiation retinopathy as an experimental model for ischemic proliferative retinopathy and rubeosis iridis. Am J Ophthalmol 1987;103:790-7.
106. Amoaku WMK, Mahon GJ, Gardiner TA, Frew L, Archer DB. Late ultrastructural changes in the retina of the rat following low-dose X-irradiation. Graefes Arch Clin Exp Ophthalmol 1992;230:569-74.
107. Miller H, Miller B, Ishibashi T, Ryan SJ. Pathogenesis of laser-induced choroidal subretinal neovascularization. Invest Ophthalmol Vis Sci 1990;31:899-908.
108. Weber ML, Manclini MA, Frank RN. Retinovitreal neovascularization in the Royal College of Surgeons rat. Curr Eye Res 1989;8:61-74.
109. Sugita G, Tano Y, Machemer R. Experimental neovascularization of the retina. Int Ophthalmol 1980;2:33-7.
110. Degowin RL, Lewis LJ, Mason RE, Borke MK, Hoak JC. Radiation-induced inhibition of human endothelial cells replicating in culture. Radiat Res 1976;68:244-50.
111. Hall EJ. Radiobiology for the radiologist. Philadelphia: JB Lippincott, 1988:1-16.
112. Powell S, McMillen TJ. DNA damage and repair following treatment with ionizing radiation. Radiother Oncol 1990; 19:95-108.
113. Wheeler K, Wierowski J. DNA accessibility: a determinant of mammalian cell differentiation. Radiat Res 1983;93: 312-18.
114. Amoaku WMK, Frew L, Mahon GJ, Gardiner TA, Archer DB. Early ultrastructural changes after low-dose X-irradiation in the retina of the rat. Eye 1989;3:638-46.
115. Sinclair WK. Cyclic X-ray responses in mammalian cells in vitro. Radiat Res 1968;33:620-43.
116. Patil MS, Locher SE, Harihan PV. Radiation-induced thymine base damage and its excision repair in active and inactive chromatin of HeLa cells. Int J Radiat Biol 1985; 48:691-700.
117. Warters RL, Childers TT. Radiation-induced thymine base damage in replicating chromatin. Radiat Res 1982;90: 564-74.
118. Chiu SM, Oleinick NL, Friedman LR, Stambrook PJ. Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation. Biochim Biophys Acta 1982; 699:15-21.
119. Winans LF, Dewey WC, Dettor CM. Repair of sublethal and potentially lethal X-ray damage in synchronous Chinese hamster cells. Radiat Res 1972;52:333-51.
120. Oleinick NL, Chiu SM, Friedman LR. Gamma radiation as a probe of chromatin structures: damage to and repair of active chromatin in the metaphase chromosome. Radiat Res 1984;98:629-41.
121. Zenneno A, Cole A. Radiosensitive structure of metaphase and interphase hamster cells as studied by low-voltage electron beam irradiation. Radiat Res 1969;39:669-84.
122. 241 Am to study radiosensitive sites in CHo cells. Radiat Res 1976;65:139-51.
123. Engennan RL, Pfaffenbach D, Davis MD. Cell turnover of capillaries. Lab Invest 1967; 17:738-43.
124. Sharma NK, Gardiner TA, Archer DB. A morphological and autoradiographic study of cell death and regeneration in the retinal microvasculature of nonnal and diabetic rats. Am J Ophthalmol 1985;100:51-60.
125. Reinhold HS. The influence of radiation on blood vessels and circulation: cell viability of the vessel wall. In: Current topics in radiation research quarterly. Amsterdam: North-Holland, 1974:9-28.