Impact of Rotavirus Vaccination on Hospitalizations and Deaths from Childhood Gastroenteritis in Botswana

Clinical Infectious Diseases

Volumn 62, Issue , 2016, Pages S168-S174

  Enane, Leslie A ^a,b   Gastañaduy, Paul A ^c   Goldfarb, David M ^b,d,e,f   Pernica, Jeffrey M ^b,f   Mokomane, Margaret ^g   Moorad, Banno ^b   Masole, Lingani ^b   Tate, Jacqueline E ^c   Parashar, Umesh D ^c   Steenhoff, Andrew P ^b,e,h  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b BOTSWANA UPENN PARTNERSHIP   (Botswana)

^c NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e UNIVERSITY OF BOTSWANA   (Botswana)

^f MCMASTER UNIVERSITY   (Canada)

^g National Health Laboratory   (Botswana)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

morbidity; mortality; rotavirus vaccine

Indexed keywords

ROTAVIRUS VACCINE; LIVE VACCINE; RIX4414 VACCINE; VACCINE;

ARTICLE; BOTSWANA; CASE CONTROL STUDY; CHILD; CHILD DEATH; CHILDHOOD DISEASE; CHILDHOOD MORTALITY; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; EPIDEMIC; GASTROENTERITIS; GROUPS BY AGE; HOSPITALIZATION; HUMAN; INFANT; MULTICENTER STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; ROTAVIRUS; SEASONAL VARIATION; VACCINATION; HOSPITALIZED CHILD; IMMUNOLOGY; MALE; MORTALITY; NEWBORN; PREVENTIVE HEALTH SERVICE; PUBLIC HEALTH; ROTAVIRUS INFECTIONS; STATISTICS AND NUMERICAL DATA; VIROLOGY;

BOTSWANA; CHILD, HOSPITALIZED; CHILD, PRESCHOOL; GASTROENTERITIS; HUMANS; IMMUNIZATION PROGRAMS; INFANT; INFANT, NEWBORN; MALE; PUBLIC HEALTH; RETROSPECTIVE STUDIES; ROTAVIRUS; ROTAVIRUS INFECTIONS; ROTAVIRUS VACCINES; VACCINATION; VACCINE POTENCY; VACCINES, ATTENUATED;

EID: 84965136054     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/civ1210     Document Type: Article

References (22)

1. Black RE, Cousens S, Johnson HL, et al. Global, regional, and national causes of child mortality in 2008: A systematic analysis. Lancet 2010; 375:1969-87.
2. Liu L, Johnson HL, Cousens S, et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 2012; 379:2151-61.
3. Tate JE, Burton AH, Boschi-Pinto C, et al. 2008 estimate of worldwide rotavirusassociated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: A systematic review and metaanalysis. Lancet Infect Dis 2012; 12:136-41.
4. Mwenda JM, Tate JE, Parashar UD, et al. African Rotavirus Surveillance Network. Pediatr Infect Dis J 2014; 33:S6-8.
5. World Health Organization. Rotavirus vaccines: an update. Wkly Epidemiol Rec 2009; 84:533-40.
6. Vesikari T, Matson DO, Dennehy P, et al. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl JMed 2006; 354:23-33.
7. Ruiz-Palacios GM, Pérez-Schael I, Velázquez FR, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med 2006; 354:11-22.
8. Madhi SA, Cunliffe NA, Steele D, et al. Effect of human rotavirus vaccine on severe diarrhea in African infants. N Engl J Med 2010; 362:289-98.
9. Armah GE, Sow SO, Breiman RF, et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: A randomised, double-blind, placebo-controlled trial. Lancet 2010; 376:606-14.
10. Zaman K, Anh DD, Victor JC, et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: A randomised, double-blind, placebo-controlled trial. Lancet 2010; 376:615-23.
11. do Carmo GMI, Yen C, Cortes J, et al. Decline in diarrhea mortality and admissions after routine childhood rotavirus immunization in Brazil: A time-series analysis. PLoS Med 2011; 8:e1001024.
12. Yen C, Armero Guardado JA, Alberto P, et al. Decline in rotavirus hospitalizations and health care visits for childhood diarrhea following rotavirus vaccination in El Salvador. Pediatr Infect Dis J 2011; 30:S6-10.
13. Quintanar-Solares M, Yen C, Richardson V, Esparza-Aguilar M, Parashar UD, Patel MM. Impact of rotavirus vaccination on diarrhea-related hospitalizations among children <5 years of age in Mexico. Pediatr Infect Dis J 2011; 30:S11-5.
14. Richardson V, Hernandez-Pichardo J, Quintanar-Solares M, et al. Effect of rotavirus vaccination on death from childhood diarrhea in Mexico. N Engl J Med 2010; 362:299-305.
15. Gastanaduy PA, Sanchez-Uribe E, Esparza-Aguilar M, et al. Effect of rotavirus vaccine on diarrhea mortality in different socioeconomic regions of Mexico. Pediatrics 2013; 131:e1115-20.
16. Nelson EAS, Glass RI. Rotavirus: realising the potential of a promising vaccine. Lancet 2010; 376:568-70.
17. World Bank, ed. Botswana-data. Available at: http://data.worldbank.org/country/botswana. Accessed 15 January 2016.
18. United Nations Inter-agency Group for Child Mortality Estimation. Levels and Trends in Child Mortality Report 2014. United Nations Children's Fund. New York. Available at: http://www.unicef.org/media/files/Levels-and-Trends-in-Child-Mortality-2014.pdf. Accessed 15 January 2016.
19. Statistics Botswana. Preliminary results-Botswana AIDS Impact Survey IV(BAIS IV), Gaborone: Statistics Botswana, 2013.
20. Welch H, Steenhoff AP, Chakalisa U, et al. Hospital-based surveillance for rotavirus gastroenteritis using molecular testing and immunoassay during the 2011 season in Botswana. Pediatr Infect Dis J 2013; 32:570-2.
21. Pernica JM, Steenhoff AP, Welch H, et al. Correlation of clinical outcomes with multiplex molecular testing of stool from children admitted to hospital with gastroenteritis in Botswana. J Pediatr Infect Dis Soc 2015; pii:piv028.
22. Msimang VMY, Page N, Groome MJ, et al. Impact of rotavirus vaccine on childhood diarrheal hospitalization after introduction into the South African public immunization program. Pediatr Infect Dis J 2013; 32:1359-64.