Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia

Journal of Antimicrobial Chemotherapy

Volumn 71, Issue 5, 2016, Pages 1264-1269

  Kumaraswamy, Monika ^a   Lin, Leo ^b   Olson, Joshua ^b   Sun, Ching Fang ^b,c   Nonejuie, Poochit ^d   Corriden, Ross ^b   Döhrmann, Simon ^b   Ali, Syed Raza ^b   Amaro, Deirdre ^e   Rohde, Manfred ^f   Pogliano, Joe ^d   Sakoulas, George ^b   Nizet, Victor ^b,g,h  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^g UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^h RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; COLISTIN; CXCL3 CHEMOKINE; INTERLEUKIN 1BETA; TISSUE CULTURE MEDIUM; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; ARTICLE; ASSAY; BACTERIAL CELL; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; BROTH DILUTION; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DRUG MEGADOSE; EPITHELIUM CELL; EXTRACELLULAR TRAP; FLUORESCENCE MICROSCOPY; HOST RESISTANCE; HUMAN; HUMAN CELL; LOADING DRUG DOSE; MINIMUM INHIBITORY CONCENTRATION; NEUTROPHIL; NEUTROPHIL KILLING ASSAY; NONHUMAN; PNEUMONIA; RESPIRATORY BURST; STENOTROPHOMONAS MALTOPHILIA; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; DISEASE MODEL; DRUG EFFECTS; DRUG POTENTIATION; GRAM-NEGATIVE BACTERIAL INFECTIONS; IMMUNOLOGY; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOUSE; PNEUMONIA, BACTERIAL; TREATMENT OUTCOME;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; AZITHROMYCIN; COLISTIN; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; NEUTROPHILS; PNEUMONIA, BACTERIAL; STENOTROPHOMONAS MALTOPHILIA; TREATMENT OUTCOME;

EID: 84965078663     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv487     Document Type: Article

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