Superoxide Dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease

Journal of Biological Chemistry

Volumn 291, Issue 17, 2016, Pages 9257-9267

  Filograna, Roberta ^a   Godena, Vinay K ^b   Sanchez Martinez, Alvaro ^b,c   Ferrari, Emanuele ^d   Casella, Luigi ^d   Beltramini, Mariano ^a   Bubacco, Luigi ^a   Whitworth, Alexander J ^b,c   Bisaglia, Marco ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HERBICIDES; NEURODEGENERATIVE DISEASES; OXYGEN; TOXICITY;

BENEFICIAL EFFECTS; DROSOPHILA MELANOGASTER; NEUROBLASTOMA CELLS; NEURODEGENERATIVE DISORDERS; OXIDATIVE DAMAGE; PARKINSON DISEASE; SUPEROXIDE DISMUTASES; THERAPEUTIC POTENTIALS;

ENZYMES;

COPPER ZINC SUPEROXIDE DISMUTASE; IMISOPASEM MANGANESE; MANGANESE SUPEROXIDE DISMUTASE; PARAQUAT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; BIOMIMETIC MATERIAL; MANGANESE; ORGANOMETALLIC COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOSOL; DROSOPHILA MELANOGASTER; FRUIT FLY MODEL; HUMAN; HUMAN CELL; MITOCHONDRION; MOTOR DYSFUNCTION; NEUROBLASTOMA CELL LINE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARAQUAT POISONING; PARKINSON DISEASE; PRIORITY JOURNAL; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; METABOLISM; OXIDATIVE STRESS; TUMOR CELL LINE;

ANIMALS; BIOMIMETIC MATERIALS; CELL LINE, TUMOR; DROSOPHILA MELANOGASTER; HUMANS; MANGANESE; MODELS, BIOLOGICAL; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; PARAQUAT; PARKINSON DISEASE; SUPEROXIDE DISMUTASE;

EID: 84965037260     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.708057     Document Type: Article

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