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Volumn 111, Issue 4, 2016, Pages 541-551

Poor correlation between clinical disease activity and mucosal inflammation, and the role of psychological comorbidity, in inflammatory bowel disease

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN; GLUCOCORTICOID; MESALAZINE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; BIOLOGICAL MARKER;

EID: 84964963327     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2016.59     Document Type: Article
Times cited : (127)

References (47)
  • 1
    • 36549001139 scopus 로고    scopus 로고
    • The prevalence and geographic distribution of Crohn?s disease and ulcerative colitis in the United States
    • Kappelman MD, Rifas-Shiman SL, Kleinman K, et al. The prevalence and geographic distribution of Crohn?s disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol 2007; 5: 1424-9
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1424-1429
    • Kappelman, M.D.1    Rifas-Shiman, S.L.2    Kleinman, K.3
  • 2
    • 83755219473 scopus 로고    scopus 로고
    • Increasing incidence and prevalence of the Inflammatory bowel diseases with time, based on systematic review
    • e42. quiz e30
    • Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the Inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142: 46-54 e42. quiz e30
    • (2012) Gastroenterology , vol.142 , pp. 46-54
    • Molodecky, N.A.1    Soon, I.S.2    Rabi, D.M.3
  • 3
    • 84897985897 scopus 로고    scopus 로고
    • Functional bowel symptoms in quiescent Inflammatory bowel diseases: Role of epithelial barrier disruption and low-grade Inflammation
    • Vivinus-Nebot M, Frin-Mathy G, Bzioueche H, et al. Functional bowel symptoms in quiescent Inflammatory bowel diseases: role of epithelial barrier disruption and low-grade Inflammation. Gut 2014; 63: 744-52
    • (2014) Gut , vol.63 , pp. 744-752
    • Vivinus-Nebot, M.1    Frin-Mathy, G.2    Bzioueche, H.3
  • 4
    • 79960212029 scopus 로고    scopus 로고
    • Symptoms in patients with ulcerative colitis in remission are associated with visceral hypersensitivity and mast cell activity
    • van Hoboken EA, Th ijssen AY, Verhaaren R, et al. Symptoms in patients with ulcerative colitis in remission are associated with visceral hypersensitivity and mast cell activity. Scand J Gastroenterol 2011; 46: 981-7
    • (2011) Scand J Gastroenterol , vol.46 , pp. 981-987
    • Van Hoboken, E.A.1    Th Ijssen, A.Y.2    Verhaaren, R.3
  • 5
    • 84867099191 scopus 로고    scopus 로고
    • Prevalence of symptoms meeting criteria for irritable bowel syndrome in Inflammatory bowel disease: Systematic review and meta-Analysis
    • Halpin SJ, Ford AC. Prevalence of symptoms meeting criteria for irritable bowel syndrome in Inflammatory bowel disease: systematic review and meta-Analysis. Am J Gastroenterol 2012; 107: 1474-82
    • (2012) Am J Gastroenterol , vol.107 , pp. 1474-1482
    • Halpin, S.J.1    Ford, A.C.2
  • 6
    • 84938413428 scopus 로고    scopus 로고
    • Prevalence of mental health disorders in Inflammatory bowel disease: An Australian outpatient cohort
    • Tribbick D, Salzberg M, Ftanou M, et al. Prevalence of mental health disorders in Inflammatory bowel disease: an Australian outpatient cohort. Clin Exp Gastroenterol 2015; 8: 197-204
    • (2015) Clin Exp Gastroenterol , vol.8 , pp. 197-204
    • Tribbick, D.1    Salzberg, M.2    Ftanou, M.3
  • 7
    • 49349107794 scopus 로고    scopus 로고
    • The Manitoba IBD cohort study: A population-based study of the prevalence of lifetime and 12-month anxiety and mood disorders
    • Walker JR, Ediger JP, Graff LA, et al. The Manitoba IBD cohort study: a population-based study of the prevalence of lifetime and 12-month anxiety and mood disorders. Am J Gastroenterol 2008; 103: 1989-97
    • (2008) Am J Gastroenterol , vol.103 , pp. 1989-1997
    • Walker, J.R.1    Ediger, J.P.2    Graff, L.A.3
  • 8
    • 84942292035 scopus 로고    scopus 로고
    • Robust association between Inflammatory bowel disease and generalized anxiety disorder: Fi ndings from a nationally representative Canadian study
    • Fuller-Thomson E, Lateef R, Sulman J. Robust association between Inflammatory bowel disease and generalized anxiety disorder: fi ndings from a nationally representative Canadian study. Inflamm Bowel Dis 2015; 21: 2341-8
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 2341-2348
    • Fuller-Thomson, E.1    Lateef, R.2    Sulman, J.3
  • 9
    • 84904384511 scopus 로고    scopus 로고
    • Evaluation of the patientreported outcomes measurement information system in a large cohort of patients with Inflammatory bowel diseases
    • e2
    • Kappelman MD, Long MD, Martin C, et al. Evaluation of the patientreported outcomes measurement information system in a large cohort of patients with Inflammatory bowel diseases. Clin Gastroenterol Hepatol 2014; 12: 1315-23 e2
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 1315-1323
    • Kappelman, M.D.1    Long, M.D.2    Martin, C.3
  • 10
    • 84925431111 scopus 로고    scopus 로고
    • Disease activity assessment in IBD: Clinical indices and biomarkers fail to predict endoscopic remission
    • Falvey JD, Hoskin T, Meijer B, et al. Disease activity assessment in IBD: clinical indices and biomarkers fail to predict endoscopic remission. Inflamm Bowel Dis 2015; 21: 824-31
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 824-831
    • Falvey, J.D.1    Hoskin, T.2    Meijer, B.3
  • 11
    • 84859604934 scopus 로고    scopus 로고
    • Surrogate markers and clinical indices, alone or combined, as indicators for endoscopic remission in anti-TNF-Treated luminal Crohn?s disease
    • af Bjorkesten CG, Nieminen U, Turunen U, et al. Surrogate markers and clinical indices, alone or combined, as indicators for endoscopic remission in anti-TNF-Treated luminal Crohn?s disease. Scand J Gastroenterol 2012; 47: 528-37
    • (2012) Scand J Gastroenterol , vol.47 , pp. 528-537
    • Af Bjorkesten, C.G.1    Nieminen, U.2    Turunen, U.3
  • 12
    • 38849204268 scopus 로고    scopus 로고
    • Crohn?s disease activity assessed by fecal calprotectin and lactoferrin: Correlation with Crohn?s disease activity index and endoscopic fi ndings
    • Sipponen T, Savilahti E, Kolho KL, et al. Crohn?s disease activity assessed by fecal calprotectin and lactoferrin: correlation with Crohn?s disease activity index and endoscopic fi ndings. Inflamm Bowel Dis 2008; 14: 40-6
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 40-46
    • Sipponen, T.1    Savilahti, E.2    Kolho, K.L.3
  • 13
    • 55149092209 scopus 로고    scopus 로고
    • Relationships between disease activity and serum and fecal biomarkers in patients with Crohn?s disease
    • Jones J, Loftus EV Jr., Panaccione R, et al. Relationships between disease activity and serum and fecal biomarkers in patients with Crohn?s disease. Clin Gastroenterol Hepatol 2008; 6: 1218-24
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1218-1224
    • Jones, J.1    Loftus, E.V.2    Panaccione, R.3
  • 14
    • 73849135965 scopus 로고    scopus 로고
    • Fecal calprotectin correlates more closely with the simple endoscopic score for Crohn?s disease (ses-cd) than crp, blood leukocytes, and the cdai
    • Schoepfer AM, Beglinger C, Straumann A, et al. Fecal calprotectin correlates more closely with the Simple Endoscopic Score for Crohn?s disease (SES-CD) than CRP, blood leukocytes, and the CDAI. Am J Gastroenterol 2010; 105: 162-9
    • (2010) Am J Gastroenterol , vol.105 , pp. 162-169
    • Schoepfer, A.M.1    Beglinger, C.2    Straumann, A.3
  • 15
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn?s disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn?s disease. N Engl J Med 2010; 362: 1383-95
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 16
    • 84904393612 scopus 로고    scopus 로고
    • Patient-reported outcomes as primary end points in clinical trials of Inflammatory bowel disease
    • e6
    • Williet N, Sandborn WJ, Peyrin-Biroulet L. Patient-reported outcomes as primary end points in clinical trials of Inflammatory bowel disease. Clin Gastroenterol Hepatol 2014; 12: 1246-56 e6
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 1246-1256
    • Williet, N.1    Sandborn, W.J.2    Peyrin-Biroulet, L.3
  • 17
    • 84894353884 scopus 로고    scopus 로고
    • Toward an integrated clinical, molecular and serological classifi cation of inflammatory bowel disease: Report of a working party of the 2005 montreal world congress of gastroenterology
    • Suppl A
    • Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classifi cation of Inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005; 19 ( Suppl A ): 5A-36A
    • (2005) Can J Gastroenterol , vol.19 , pp. 5A-36A
    • Silverberg, M.S.1    Satsangi, J.2    Ahmad, T.3
  • 18
    • 0019319257 scopus 로고
    • A simple index of Crohn?s-disease activity
    • Harvey RF, Bradshaw JM. A simple index of Crohn?s-disease activity. Lancet 1980; 1: 514
    • (1980) Lancet , vol.1 , pp. 514
    • Harvey, R.F.1    Bradshaw, J.M.2
  • 19
    • 0031812412 scopus 로고    scopus 로고
    • A simple clinical colitis activity index
    • Walmsley RS, Ayres RC, Pounder RE, et al. A simple clinical colitis activity index. Gut 1998; 43: 29-32
    • (1998) Gut , vol.43 , pp. 29-32
    • Walmsley, R.S.1    Ayres, R.C.2    Pounder, R.E.3
  • 20
    • 77949652854 scopus 로고    scopus 로고
    • Correlation between the Crohn?s disease activity and harvey-bradshaw indices in assessing Crohn?s disease severity
    • Vermeire S, Schreiber S, Sandborn WJ, et al. Correlation between the Crohn?s disease activity and Harvey-Bradshaw indices in assessing Crohn?s disease severity. Clin Gastroenterol Hepatol 2010; 8: 357-63
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 357-363
    • Vermeire, S.1    Schreiber, S.2    Sandborn, W.J.3
  • 21
    • 0346665816 scopus 로고    scopus 로고
    • Defining relapse of ulcerative colitis using a symptom-based activity index
    • Jowett SL, Seal CJ, Phillips E, et al. Defining relapse of ulcerative colitis using a symptom-based activity index. Scand J Gastroenterol 2003; 38: 164-71
    • (2003) Scand J Gastroenterol , vol.38 , pp. 164-171
    • Jowett, S.L.1    Seal, C.J.2    Phillips, E.3
  • 22
    • 84888613326 scopus 로고    scopus 로고
    • Comparison of two commercially available serologic kits for the detection of fecal calprotecin
    • Loitsch SM, Berger C, Hartmann F, et al. Comparison of two commercially available serologic kits for the detection of fecal calprotecin. Gatroenterology 2010; 138: S-528
    • (2010) Gatroenterology , vol.138 , pp. S-528
    • Loitsch, S.M.1    Berger, C.2    Hartmann, F.3
  • 23
    • 84880036845 scopus 로고    scopus 로고
    • Concept for a rapid point-of-care calprotectin diagnostic test for diagnosis and disease activity monitoring in patients with Inflammatory bowel disease: Expert clinical opinion
    • Rogler G, Aldeguer X, Kruis W, et al. Concept for a rapid point-of-care calprotectin diagnostic test for diagnosis and disease activity monitoring in patients with Inflammatory bowel disease: expert clinical opinion. J Crohns Colitis 2013; 7: 670-7
    • (2013) J Crohns Colitis , vol.7 , pp. 670-677
    • Rogler, G.1    Aldeguer, X.2    Kruis, W.3
  • 24
    • 84936846060 scopus 로고    scopus 로고
    • The relationship among perceived stress, symptoms, and Inflammation in persons with Inflammatory bowel disease
    • Targownik LE, Sexton KA, Bernstein MT, et al. The relationship among perceived stress, symptoms, and Inflammation in persons with Inflammatory bowel disease. Am J Gastroenterol 2015; 110: 1001-12
    • (2015) Am J Gastroenterol , vol.110 , pp. 1001-1012
    • Targownik, L.E.1    Sexton, K.A.2    Bernstein, M.T.3
  • 25
    • 84862524860 scopus 로고    scopus 로고
    • Fecal calprotectin is a surrogate marker for endoscopic lesions in Inflammatory bowel disease
    • D?Haens G, Ferrante M, Vermeire S, et al. Fecal calprotectin is a surrogate marker for endoscopic lesions in Inflammatory bowel disease. Inflamm Bowel Dis 2012; 18: 2218-24
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 2218-2224
    • Dhaens, G.1    Ferrante, M.2    Vermeire, S.3
  • 26
    • 84905464937 scopus 로고    scopus 로고
    • Meta-Analysis: Fecal calprotectin for assessment of Inflammatory bowel disease activity
    • Lin JF, Chen JM, Zuo JH, et al. Meta-Analysis: fecal calprotectin for assessment of Inflammatory bowel disease activity. Inflamm Bowel Dis 2014; 20: 1407-15
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1407-1415
    • Lin, J.F.1    Chen, J.M.2    Zuo, J.H.3
  • 28
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361-70
    • (1983) Acta Psychiatr Scand , vol.67 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2
  • 29
    • 0033544340 scopus 로고    scopus 로고
    • Validation and utility of a self-report version of prime-md: The phq primary care study primary care evaluation of mental disorders patient health questionnaire
    • Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA 1999; 282: 1737-44
    • (1999) JAMA , vol.282 , pp. 1737-1744
    • Spitzer, R.L.1    Kroenke, K.2    Williams, J.B.3
  • 30
    • 0033825905 scopus 로고    scopus 로고
    • Validity and utility of the prime-md patient health questionnaire in assessment of 3000 obstetricgynecologic patients: The prime-md patient health questionnaire obstetrics-gynecology study
    • Spitzer RL, Williams JB, Kroenke K, et al. Validity and utility of the PRIME-MD patient health questionnaire in assessment of 3000 obstetricgynecologic patients: the PRIME-MD Patient Health Questionnaire Obstetrics-Gynecology Study. Am J Obstet Gynecol 2000; 183: 759-69
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 759-769
    • Spitzer, R.L.1    Williams, J.B.2    Kroenke, K.3
  • 31
    • 0025328886 scopus 로고
    • The prevalence of symptoms in medical outpatients and the adequacy of therapy
    • Kroenke K, Arrington ME, Mangelsdorff AD. The prevalence of symptoms in medical outpatients and the adequacy of therapy. Arch Intern Med 1990; 150: 1685-9
    • (1990) Arch Intern Med , vol.150 , pp. 1685-1689
    • Kroenke, K.1    Arrington, M.E.2    Mangelsdorff, A.D.3
  • 32
    • 84888299584 scopus 로고    scopus 로고
    • Validation of the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care
    • e1
    • Ford AC, Bercik P, Morgan DG, et al. Validation of the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care. Gastroenterology 2013; 145: 1262-70 e1
    • (2013) Gastroenterology , vol.145 , pp. 1262-1270
    • Ford, A.C.1    Bercik, P.2    Morgan, D.G.3
  • 33
    • 84932131823 scopus 로고    scopus 로고
    • Fecal calprotectin in ileal Crohn?s disease: Relationship with magnetic resonance enterography and a pathology score
    • Cerrillo E, Beltran B, Pous S, et al. Fecal calprotectin in ileal Crohn?s disease: relationship with magnetic resonance enterography and a pathology score. Inflamm Bowel Dis 2015; 21: 1572-9
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 1572-1579
    • Cerrillo, E.1    Beltran, B.2    Pous, S.3
  • 34
    • 84928399624 scopus 로고    scopus 로고
    • Is faecal calprotectin equally useful in all Crohn?s disease locations? A prospective, comparative study
    • Stawczyk-Eder K, Eder P, Lykowska-Szuber L, et al. Is faecal calprotectin equally useful in all Crohn?s disease locations?. A prospective, comparative study. Arch Med Sci 2015; 11: 353-61
    • (2015) Arch Med Sci , vol.11 , pp. 353-361
    • Stawczyk-Eder, K.1    Eder, P.2    Lykowska-Szuber, L.3
  • 35
    • 84922739153 scopus 로고    scopus 로고
    • Small bowel capsule endoscopy in the management of established Crohn?s disease: Clinical impact, safety, and correlation with Inflammatory biomarkers
    • Kopylov U, Nemeth A, Koulaouzidis A, et al. Small bowel capsule endoscopy in the management of established Crohn?s disease: clinical impact, safety, and correlation with Inflammatory biomarkers. Inflamm Bowel Dis 2015; 21: 93-100
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 93-100
    • Kopylov, U.1    Nemeth, A.2    Koulaouzidis, A.3
  • 36
    • 84867551570 scopus 로고    scopus 로고
    • Prevalence of, and predictors of, bile acid malabsorption in outpatients with chronic diarrhea
    • e538
    • Gracie DJ, Kane JS, Mumtaz S, et al. Prevalence of, and predictors of, bile acid malabsorption in outpatients with chronic diarrhea. Neurogastroenterol Motil 2012; 24: 983-e538
    • (2012) Neurogastroenterol Motil , vol.24 , pp. 983
    • Gracie, D.J.1    Kane, J.S.2    Mumtaz, S.3
  • 37
    • 84945177857 scopus 로고    scopus 로고
    • Glucose breath test and Crohn?s disease: Diagnosis of small intestinal bacterial overgrowth and evaluation of therapeutic response
    • Greco A, Caviglia GP, Brignolo P, et al. Glucose breath test and Crohn?s disease: diagnosis of small intestinal bacterial overgrowth and evaluation of therapeutic response. Scand J Gastroenterol 2015; 50: 1376-81
    • (2015) Scand J Gastroenterol , vol.50 , pp. 1376-1381
    • Greco, A.1    Caviglia, G.P.2    Brignolo, P.3
  • 38
    • 84869218485 scopus 로고    scopus 로고
    • Mood disorders in Inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors
    • Goodhand JR, Wahed M, Mawdsley JE, et al. Mood disorders in Inflammatory bowel disease: relation to diagnosis, disease activity, perceived stress, and other factors. Inflamm Bowel Dis 2012; 18: 2301-9
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 2301-2309
    • Goodhand, J.R.1    Wahed, M.2    Mawdsley, J.E.3
  • 39
    • 79954553840 scopus 로고    scopus 로고
    • Functional gastrointestinal disorders in Inflammatory bowel disease: Impact on quality of life and psychological status
    • Bryant RV, van Langenberg DR, Holtmann GJ, et al. Functional gastrointestinal disorders in Inflammatory bowel disease: impact on quality of life and psychological status. J Gastroenterol Hepatol 2011; 26: 916-23
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 916-923
    • Bryant, R.V.1    Van Langenberg, D.R.2    Holtmann, G.J.3
  • 40
    • 77949317085 scopus 로고    scopus 로고
    • Psychological distress, somatization, and defense mechanisms associated with quality of life in Inflammatory bowel disease patients
    • Hyphantis TN, Tomenson B, Bai M, et al. Psychological distress, somatization, and defense mechanisms associated with quality of life in Inflammatory bowel disease patients. Dig Dis Sci 2010; 55: 724-32
    • (2010) Dig Dis Sci , vol.55 , pp. 724-732
    • Hyphantis, T.N.1    Tomenson, B.2    Bai, M.3
  • 41
    • 84941260661 scopus 로고    scopus 로고
    • Selecting therapeutic targets in Inflammatory bowel disease (STRIDE): Determining therapeutic goals for treat-To-Target
    • Peyrin-Biroulet L, Sandborn W, Sands BE, et al. Selecting therapeutic targets in Inflammatory bowel disease (STRIDE): determining therapeutic goals for treat-To-Target. Am J Gastroenterol 2015; 110: 1324-38
    • (2015) Am J Gastroenterol , vol.110 , pp. 1324-1338
    • Peyrin-Biroulet, L.1    Sandborn, W.2    Sands, B.E.3
  • 42
    • 84943618535 scopus 로고    scopus 로고
    • Development of interim patient-reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials
    • Jairath V, Khanna R, Zou GY, et al. Development of interim patient-reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials. Aliment Pharmacol Ther 2015; 42: 1200-10
    • (2015) Aliment Pharmacol Ther , vol.42 , pp. 1200-1210
    • Jairath, V.1    Khanna, R.2    Zou, G.Y.3
  • 43
    • 84915735329 scopus 로고    scopus 로고
    • A retrospective analysis: The development of patient reported outcome measures for the assessment of Crohn?s disease activity
    • Khanna R, Zou G, D?Haens G, et al. A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn?s disease activity. Aliment Pharmacol Ther 2015; 41: 77-86
    • (2015) Aliment Pharmacol Ther , vol.41 , pp. 77-86
    • Khanna, R.1    Zou, G.2    Dhaens, G.3
  • 44
    • 84942982258 scopus 로고    scopus 로고
    • Randomised clinical study: Discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis
    • Jharap B, Sandborn WJ, Reinisch W, et al. Randomised clinical study: discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis. Aliment Pharmacol Ther 2015; 42: 1082-92
    • (2015) Aliment Pharmacol Ther , vol.42 , pp. 1082-1092
    • Jharap, B.1    Sandborn, W.J.2    Reinisch, W.3
  • 45
    • 84955591009 scopus 로고    scopus 로고
    • Does computerized cognitive behavioral therapy help people with Inflammatory bowel disease? A randomized controlled trial
    • McCombie A, Gearry R, Andrews J, et al. Does computerized cognitive behavioral therapy help people with Inflammatory bowel disease?. A randomized controlled trial. Inflamm Bowel Dis 2015
    • (2015) Inflamm Bowel Dis
    • McCombie, A.1    Gearry, R.2    Andrews, J.3
  • 46
    • 84929167642 scopus 로고    scopus 로고
    • Cognitive-behavioural therapy has no Effect on disease activity but improves quality of life in subgroups of patients with Inflammatory bowel disease: A pilot randomised controlled trial
    • Mikocka-Walus A, Bampton P, Hetzel D, et al. Cognitive-behavioural therapy has no Effect on disease activity but improves quality of life in subgroups of patients with Inflammatory bowel disease: a pilot randomised controlled trial. BMC Gastroenterol 2015; 15: 54
    • (2015) BMC Gastroenterol , vol.15 , pp. 54
    • Mikocka-Walus, A.1    Bampton, P.2    Hetzel, D.3


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