-
1
-
-
84883214212
-
Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis
-
S. Wang, Y. Wang, Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis. Biochim. Biophys. Acta 1829, 1126-1135 (2013).
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 1126-1135
-
-
Wang, S.1
Wang, Y.2
-
2
-
-
84895875371
-
Citrullination regulates pluripotency and histone H1 binDing to chromatin
-
M. A. Christophorou, G. Castelo-Branco, R. P. Halley-Stott, C. S. Oliveira, R. Loos, A. Radzisheuskaya, K. A. Mowen, P. Bertone, J. C. R. Silva, M. Zernicka-Goetz, M. L. Nielsen, J. B. Gurdon, T. Kouzarides, Citrullination regulates pluripotency and histone H1 binDing to chromatin. Nature 507, 104-108 (2014).
-
(2014)
Nature
, vol.507
, pp. 104-108
-
-
Christophorou, M.A.1
Castelo-Branco, G.2
Halley-Stott, R.P.3
Oliveira, C.S.4
Loos, R.5
Radzisheuskaya, A.6
Mowen, K.A.7
Bertone, P.8
Silva, J.C.R.9
Zernicka-Goetz, M.10
Nielsen, M.L.11
Gurdon, J.B.12
Kouzarides, T.13
-
3
-
-
84866933793
-
Citrullination of histone H3 interferes with HP1-meDiated transcriptional repression
-
P. Sharma, S. Azebi, P. England, T. Christensen, A. Møller-Larsen, T. Petersen, E. Batsché, C. Muchardt, Citrullination of histone H3 interferes with HP1-meDiated transcriptional repression. PLOS Genet. 8, e1002934 (2012).
-
(2012)
PLOS Genet.
, vol.8
, pp. e1002934
-
-
Sharma, P.1
Azebi, S.2
England, P.3
Christensen, T.4
Møller-Larsen, A.5
Petersen, T.6
Batsché, E.7
Muchardt, C.8
-
4
-
-
79959821077
-
Genome-wide analysis reveals PADi4 cooperateswith Elk-1 to activate c-Fos expression in breast cancer cells
-
X. Zhang, M. J. Gamble, S. Stadler, B. D. Cherrington, C. P. Causey, P. R. Thompson, M. S. Roberson, W. L. Kraus, S. A. Coonrod, Genome-wide analysis reveals PADi4 cooperateswith Elk-1 to activate c-Fos expression in breast cancer cells. PLOS Genet. 7, e1002112 (2011).
-
(2011)
PLOS Genet.
, vol.7
, pp. e1002112
-
-
Zhang, X.1
Gamble, M.J.2
Stadler, S.3
Cherrington, B.D.4
Causey, C.P.5
Thompson, P.R.6
Roberson, M.S.7
Kraus, W.L.8
Coonrod, S.A.9
-
5
-
-
85039035343
-
To live or let Die-Complexity within the E2F1 pathway
-
A. P. Roworth, F. Ghari, N. B. La Thangue, To live or let Die-Complexity within the E2F1 pathway. Mol. Cell. Oncol. 2, e970480 (2015).
-
(2015)
Mol. Cell. Oncol.
, vol.2
, pp. e970480
-
-
Roworth, A.P.1
Ghari, F.2
La Thangue, N.B.3
-
6
-
-
34547838179
-
Genome-wide mapping of RELA(p65) binDing identifies E2F1 as a transcriptional activator recruited by NF-kB upon TLR4 activation
-
C.-A. Lim, F. Yao, J. J.-Y. Wong, J. George, H. Xu, K. P. Chiu, W.-K. Sung, L. Lipovich, V. B. Vega, J. Chen, A. Shahab, X. D. Zhao, M. Hibberd, C.-L. Wei, B. Lim, H.-H. Ng, Y. Ruan, K.-C. Chin, Genome-wide mapping of RELA(p65) binDing identifies E2F1 as a transcriptional activator recruited by NF-kB upon TLR4 activation. Mol. Cell 27, 622-635 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 622-635
-
-
Lim, C.-A.1
Yao, F.2
Wong, J.J.-Y.3
George, J.4
Xu, H.5
Chiu, K.P.6
Sung, W.-K.7
Lipovich, L.8
Vega, V.B.9
Chen, J.10
Shahab, A.11
Zhao, X.D.12
Hibberd, M.13
Wei, C.-L.14
Lim, B.15
Ng, H.-H.16
Ruan, Y.17
Chin, K.-C.18
-
7
-
-
84885378025
-
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1
-
S. Zheng, J. Moehlenbrink, Y.-C. Lu, L.-P. Zalmas, C. A. Sagum, S. Carr, J. F. McGouran, L. Alexander, O. Fedorov, S. Munro, B. Kessler, M. T. Bedford, Q. Yu, N. B. La Thangue, Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1. Mol. Cell 52, 37-51 (2013).
-
(2013)
Mol. Cell
, vol.52
, pp. 37-51
-
-
Zheng, S.1
Moehlenbrink, J.2
Lu, Y.-C.3
Zalmas, L.-P.4
Sagum, C.A.5
Carr, S.6
McGouran, J.F.7
Alexander, L.8
Fedorov, O.9
Munro, S.10
Kessler, B.11
Bedford, M.T.12
Yu, Q.13
La Thangue, N.B.14
-
8
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
G. L. Cuthbert, S. Daujat, A. W. Snowden, H. Erdjument-Bromage, T. Hagiwara, M. Yamada, R. Schneider, P. D. Gregory, P. Tempst, A. J. Bannister, T. Kouzarides, Histone deimination antagonizes arginine methylation. Cell 118, 545-553 (2004).
-
(2004)
Cell
, vol.118
, pp. 545-553
-
-
Cuthbert, G.L.1
Daujat, S.2
Snowden, A.W.3
Erdjument-Bromage, H.4
Hagiwara, T.5
Yamada, M.6
Schneider, R.7
Gregory, P.D.8
Tempst, P.9
Bannister, A.J.10
Kouzarides, T.11
-
9
-
-
84862945967
-
Synthesis and screening of a haloacetamiDine containing library to identify PAD4 selective inhibitors
-
J. E. Jones, J. L. Slack, P. Fang, X. Zhang, V. Subramanian, C. P. Causey, S. A. Coonrod, M. Guo, P. R. Thompson, Synthesis and screening of a haloacetamiDine containing library to identify PAD4 selective inhibitors. ACS Chem. Biol. 7, 160-165 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 160-165
-
-
Jones, J.E.1
Slack, J.L.2
Fang, P.3
Zhang, X.4
Subramanian, V.5
Causey, C.P.6
Coonrod, S.A.7
Guo, M.8
Thompson, P.R.9
-
10
-
-
27344435774
-
Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles
-
A. Subramanian, P. Tamayo, V. K. Mootha, S. Mukherjee, B. L. Ebert, M. A. Gillette, A. Paulovich, S. L. Pomeroy, T. R. Golub, E. S. Lander, J. P. Mesirov, Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U. S. A. 102, 15545-15550 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
11
-
-
84874969184
-
PANTHER in 2013: Modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees
-
H. Mi, A. Muruganujan, P. D. Thomas, PANTHER in 2013: Modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees. Nucleic Acids Res. 41, D377-D386 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D377-D386
-
-
Mi, H.1
Muruganujan, A.2
Thomas, P.D.3
-
12
-
-
79959983507
-
CENTDiST: Discovery of co-associated factors by motif Distribution
-
Z. Zhang, C. W. Chang, W. L. Goh, W.-K. Sung, E. Cheung, CENTDiST: Discovery of co-associated factors by motif Distribution. Nucleic Acids Res. 39, W391-W399 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. W391-W399
-
-
Zhang, Z.1
Chang, C.W.2
Goh, W.L.3
Sung, W.-K.4
Cheung, E.5
-
13
-
-
0024151602
-
The HL60 cell line: A model system for studying human myeloid cell Differentiation
-
G. D. Birnie, The HL60 cell line: A model system for studying human myeloid cell Differentiation. Br. J. Cancer Suppl. 9, 41-45 (1988).
-
(1988)
Br. J. Cancer Suppl.
, vol.9
, pp. 41-45
-
-
Birnie, G.D.1
-
14
-
-
0033600723
-
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1a, 25-Dihydroxyvitamin D3
-
K. Nakashima, T. Hagiwara, A. Ishigami, S. Nagata, H. Asaga, M. Kuramoto, T. Senshu, M. Yamada, Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1a, 25-Dihydroxyvitamin D3. J. Biol. Chem. 274, 27786-27792 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27786-27792
-
-
Nakashima, K.1
Hagiwara, T.2
Ishigami, A.3
Nagata, S.4
Asaga, H.5
Kuramoto, M.6
Senshu, T.7
Yamada, M.8
-
15
-
-
45449097039
-
Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil Differentiation of human leukaemia HL-60 cells
-
F. Mollinedo, R. López-Pérez, C. Gajate, Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil Differentiation of human leukaemia HL-60 cells. Gene 419, 16-26 (2008).
-
(2008)
Gene
, vol.419
, pp. 16-26
-
-
Mollinedo, F.1
López-Pérez, R.2
Gajate, C.3
-
16
-
-
33748047128
-
RB and cell cycle progression
-
C. Giacinti, A. Giordano, RB and cell cycle progression. Oncogene 25, 5220-5227 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 5220-5227
-
-
Giacinti, C.1
Giordano, A.2
-
17
-
-
84949904309
-
Peptidylarginine deiminase inhibition Disrupts NET formation and protects against kidney, skin and vascular Disease in lupus-prone MRL/lpr mice
-
J. S. Knight, V. Subramanian, A. A. O'Dell, S. Yalavarthi, W. Zhao, C. K. Smith, J. B. Hodgin, P. R. Thompson, M. J. Kaplan, Peptidylarginine deiminase inhibition Disrupts NET formation and protects against kidney, skin and vascular Disease in lupus-prone MRL/lpr mice. Ann. Rheum. Dis. 74, 2199-2206 (2014).
-
(2014)
Ann. Rheum. Dis.
, vol.74
, pp. 2199-2206
-
-
Knight, J.S.1
Subramanian, V.2
O'Dell, A.A.3
Yalavarthi, S.4
Zhao, W.5
Smith, C.K.6
Hodgin, J.B.7
Thompson, P.R.8
Kaplan, M.J.9
-
18
-
-
84925506325
-
Inhibition of PAD4 activity is sufficient to Disruptmouse and humanNET formation
-
H. D. Lewis, J. Liddle, J. E. Coote, S. J. Atkinson, M. D. Barker, B. D. Bax, K. L. Bicker, R. P. Bingham, M. Campbell, Y. H. Chen, C.-w. Chung, P. D. Craggs, R. P. Davis, D. Eberhard, G. Joberty, K. E. Lind, K. Locke, C. Maller, K. Martinod, C. Patten, O. Polyakova, C. E. Rise, M. RüDiger, R. J. Sheppard, D. J. Slade, P. Thomas, J. Thorpe, G. Yao, G. Drewes, D. D. Wagner, P. R. Thompson, R. K. Prinjha, D. M. Wilson, Inhibition of PAD4 activity is sufficient to Disruptmouse and humanNET formation. Nat. Chem. Biol. 11, 189-191 (2015).
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 189-191
-
-
Lewis, H.D.1
Liddle, J.2
Coote, J.E.3
Atkinson, S.J.4
Barker, M.D.5
Bax, B.D.6
Bicker, K.L.7
Bingham, R.P.8
Campbell, M.9
Chen, Y.H.10
Chung, C.-W.11
Craggs, P.D.12
Davis, R.P.13
Eberhard, D.14
Joberty, G.15
Lind, K.E.16
Locke, K.17
Maller, C.18
Martinod, K.19
Patten, C.20
Polyakova, O.21
Rise, C.E.22
RüDiger, M.23
Sheppard, R.J.24
Slade, D.J.25
Thomas, P.26
Thorpe, J.27
Yao, G.28
Drewes, G.29
Wagner, D.D.30
Thompson, P.R.31
Prinjha, R.K.32
Wilson, D.M.33
more..
-
20
-
-
67649648237
-
Control of inducible gene expression by signaldependent transcriptional elongation
-
D. C. Hargreaves, T. Horng, R. Medzhitov, Control of inducible gene expression by signaldependent transcriptional elongation. Cell 138, 129-145 (2009).
-
(2009)
Cell
, vol.138
, pp. 129-145
-
-
Hargreaves, D.C.1
Horng, T.2
Medzhitov, R.3
-
21
-
-
84859181036
-
Histone recognition and large-scale structural analysis of the human bromodomain family
-
P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.-P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson, A.-C. Gingras, C. H. Arrowsmith, S. Knapp, Histone recognition and large-scale structural analysis of the human bromodomain family. Cell 149, 214-231 (2012).
-
(2012)
Cell
, vol.149
, pp. 214-231
-
-
Filippakopoulos, P.1
Picaud, S.2
Mangos, M.3
Keates, T.4
Lambert, J.-P.5
Barsyte-Lovejoy, D.6
Felletar, I.7
Volkmer, R.8
Müller, S.9
Pawson, T.10
Gingras, A.-C.11
Arrowsmith, C.H.12
Knapp, S.13
-
22
-
-
0343484254
-
Regulation of E2F1 activity by acetylation
-
M. A. Martínez-Balbás, U.-M. Bauer, S. J. Nielsen, A. Brehm, T. Kouzarides, Regulation of E2F1 activity by acetylation. EMBO J. 19, 662-671 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 662-671
-
-
Martínez-Balbás, M.A.1
Bauer, U.-M.2
Nielsen, S.J.3
Brehm, A.4
Kouzarides, T.5
-
23
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
P. Filippakopoulos, J. Qi, S. Picaud, Y. Shen, W. B. Smith, O. Fedorov, E. M. Morse, T. Keates, T. T. Hickman, I. Felletar, M. Philpott, S. Munro, M. R. McKeown, Y. Wang, A. L. Christie, N. West, M. J. Cameron, B. Schwartz, T. D. Heightman, N. La Thangue, C. A. French, O. Wiest, A. L. Kung, S. Knapp, J. E. Bradner, Selective inhibition of BET bromodomains. Nature 468, 1067-1073 (2010).
-
(2010)
Nature
, vol.468
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
Morse, E.M.7
Keates, T.8
Hickman, T.T.9
Felletar, I.10
Philpott, M.11
Munro, S.12
McKeown, M.R.13
Wang, Y.14
Christie, A.L.15
West, N.16
Cameron, M.J.17
Schwartz, B.18
Heightman, T.D.19
La Thangue, N.20
French, C.A.21
Wiest, O.22
Kung, A.L.23
Knapp, S.24
Bradner, J.E.25
more..
-
24
-
-
42049121842
-
Protocol for the induction of arthritis in C57BL/6 mice
-
J. J. Inglis, E. Šimelyte, F. E. McCann, G. Criado, R. O. Williams, Protocol for the induction of arthritis in C57BL/6 mice. Nat. Protoc. 3, 612-618 (2008).
-
(2008)
Nat. Protoc.
, vol.3
, pp. 612-618
-
-
Inglis, J.J.1
Šimelyte, E.2
McCann, F.E.3
Criado, G.4
Williams, R.O.5
-
25
-
-
84886810819
-
BET bromodomain inhibition suppresses TH17-meDiated pathology
-
D. A. Mele, A. Salmeron, S. Ghosh, H.-R. Huang, B. M. Bryant, J. M. Lora, BET bromodomain inhibition suppresses TH17-meDiated pathology. J. Exp. Med. 210, 2181-2190 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2181-2190
-
-
Mele, D.A.1
Salmeron, A.2
Ghosh, S.3
Huang, H.-R.4
Bryant, B.M.5
Lora, J.M.6
-
26
-
-
79959790271
-
Novel regulators of the systemic response to lipopolysaccharide
-
I. V. Yang, S. Alper, B. Lackford, H. Rutledge, L. A. Warg, L. H. Burch, D. A. Schwartz, Novel regulators of the systemic response to lipopolysaccharide. Am. J. Respir. Cell Mol. Biol. 45, 393-402 (2011).
-
(2011)
Am. J. Respir. Cell Mol. Biol.
, vol.45
, pp. 393-402
-
-
Yang, I.V.1
Alper, S.2
Lackford, B.3
Rutledge, H.4
Warg, L.A.5
Burch, L.H.6
Schwartz, D.A.7
-
27
-
-
40749128547
-
Histone deimination as a response to inflammatory stimuli in neutrophils
-
I. Neeli, S. N. Khan, M. RaDic, Histone deimination as a response to inflammatory stimuli in neutrophils. J. Immunol. 180, 1895-1902 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 1895-1902
-
-
Neeli, I.1
Khan, S.N.2
RaDic, M.3
-
28
-
-
84862812370
-
Arginine methylation controls growth regulation by E2F-1
-
E.-C. Cho, S. Zheng, S. Munro, G. Liu, S. M. Carr, J. Moehlenbrink, Y.-C. Lu, L. Stimson, O. Khan, R. Konietzny, J. McGouran, A. S. Coutts, B. Kessler, D. J. Kerr, N. B. Thangue, Arginine methylation controls growth regulation by E2F-1. EMBO J. 31, 1785-1797 (2012).
-
(2012)
EMBO J.
, vol.31
, pp. 1785-1797
-
-
Cho, E.-C.1
Zheng, S.2
Munro, S.3
Liu, G.4
Carr, S.M.5
Moehlenbrink, J.6
Lu, Y.-C.7
Stimson, L.8
Khan, O.9
Konietzny, R.10
McGouran, J.11
Coutts, A.S.12
Kessler, B.13
Kerr, D.J.14
Thangue, N.B.15
-
29
-
-
84946100079
-
The UCSC Genome Browser database: 2015 update
-
K. R. Rosenbloom, J. Armstrong, G. P. Barber, J. Casper, H. Clawson, M. Diekhans, T. R. Dreszer, P. A. Fujita, L. Guruvadoo, M. Haeussler, R. A. Harte, S. Heitner, G. Hickey, A. S. Hinrichs, R. Hubley, D. Karolchik, K. Learned, B. T. Lee, C. H. Li, K. H. Miga, N. Nguyen, B. Paten, B. J. Raney, A. F. A. Smit, M. L. Speir, A. S. Zweig, D. Haussler, R. M. Kuhn, W. J. Kent, The UCSC Genome Browser database: 2015 update. Nucleic Acids Res. 43, D670-D681 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D670-D681
-
-
Rosenbloom, K.R.1
Armstrong, J.2
Barber, G.P.3
Casper, J.4
Clawson, H.5
Diekhans, M.6
Dreszer, T.R.7
Fujita, P.A.8
Guruvadoo, L.9
Haeussler, M.10
Harte, R.A.11
Heitner, S.12
Hickey, G.13
Hinrichs, A.S.14
Hubley, R.15
Karolchik, D.16
Learned, K.17
Lee, B.T.18
Li, C.H.19
Miga, K.H.20
Nguyen, N.21
Paten, B.22
Raney, B.J.23
Smit, A.F.A.24
Speir, M.L.25
Zweig, A.S.26
Haussler, D.27
Kuhn, R.M.28
Kent, W.J.29
more..
|