Risk analysis of ischemic-type biliary lesions after liver transplant using octogenarian donors

Liver Transplantation

Volumn 22, Issue 5, 2016, Pages 588-598

  Ghinolfi, Davide ^a   De Simone, Paolo ^a   Lai, Quirino ^a   Pezzati, Daniele ^a   Coletti, Laura ^a   Balzano, Emanuele ^a   Arenga, Giuseppe ^a   Carrai, Paola ^a   Grande, Gennaro ^a   Pollina, Luca ^b   Campani, Daniela ^b   Biancofiore, Gianni ^a   Filipponi, Franco ^a  

^a UNIVERSITY HOSPITAL OF PISA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AGED; ARTICLE; BALLOON DILATATION; BILE LEAKAGE; BILIARY STONE; BILIARY TRACT DISEASE; CADAVER DONOR; CHOLESTASIS; DIABETES MELLITUS; DONOR; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; FOLLOW UP; GRAFT SURVIVAL; HAZARD RATIO; HEMODYNAMICS; HEPATOJEJUNOSTOMY; HUMAN; HUMAN TISSUE; ISCHEMIC TYPE BILIARY LESION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MODEL FOR END STAGE LIVER DISEASE SCORE; MULTIVARIATE ANALYSIS; OCTOGENARIAN DONOR; PRIORITY JOURNAL; RISK ASSESSMENT; VATER PAPILLOTOMY; VERY ELDERLY; ALGORITHM; END STAGE LIVER DISEASE; HEPATOBILIARY SYSTEM; INJURIES; PATHOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; TIME FACTOR; TREATMENT OUTCOME;

AGED, 80 AND OVER; ALGORITHMS; BILIARY TRACT; END STAGE LIVER DISEASE; FEMALE; GRAFT SURVIVAL; HEMODYNAMICS; HUMANS; LIVER TRANSPLANTATION; MALE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; ROC CURVE; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TISSUE DONORS; TREATMENT OUTCOME;

EID: 84964726557     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.24401     Document Type: Article

References (45)

1. Busuttil RW, Tanaka K,. The utility of marginal donors in liver transplantation. Liver Transpl 2003; 9: 651-663.
2. Lai JC, Covinsky K, Feng S,. The octogenarian donor: can the liver be "younger than stated age"? Am J Transplant 2014; 14: 1962-1963.
3. Pirenne J, Monbaliu D, Van Gelder F, Van Hees D, Aerts R, Verslype C, et al., Liver transplantation using livers from septuagenarian and octogenarian donors: an underused strategy to reduce mortality on the waiting list. Transplant Proc 2005; 37: 1180-1181.
4. Ploeg RJ, D'Alessandro AM, Knechtle SJ, Stegall MD, Pirsch JD, Hoffmann RM, et al., Risk factors for primary dysfunction after liver transplantation-a multivariate analysis. Transplantation 1993; 55: 807-813.
5. Cameron AM, Ghobrial RM, Yersiz H, Farmer DG, Lipshutz GS, Gordon SA, et al., Optimal utilization of donor grafts with extended criteria. A single-center experience in over 1000 liver transplants. Ann Surg 2006; 243: 748-753.
6. Nickkholgh A, Weitz J, Encke J, Sauer P, Mehrabi A, Büchler MW, et al., Utilization of extended donor criteria in liver transplantation: a comprehensive review of the literature. Nephrol Dial Transplant 2007; 22 (suppl 8): 29-36.
7. Berenguer M, Prieto M, San Juan F, Rayón JM, Martinez F, Carrasco D, et al., Contribution of donor age to the recent decrease in patient survival among HCV-infected liver transplant recipients. Hepatology 2002; 36: 202-210.
8. Feng S, Goodrich NP, Bragg-Gresham JL, Dykstra DM, Punch JD, DebRoy MA, et al., Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant 2006; 6: 783-790.
9. Heidenhain C, Pratschke J, Puhl G, Neumann U, Pascher A, Veltzke-Schlieker W, Neuhaus P,. Incidence of and risk factors for ischemic-type biliary lesions following orthotopic liver transplantation. Transpl Int 2010; 23: 14-22.
10. Seehofer D, Eurich D, Veltzke-Schlieker W, Neuhaus P,. Biliary complications after liver transplantation: old problems and new challenges. Am J Transplant 2013; 13: 253-265.
11. Abt P, Crawford M, Desai N, Markmann J, Olthoff K, Shaked A,. Liver transplantation from controlled non-heart-beating donors: an increased incidence of biliary complications. Transplantation 2003; 75: 1659-1663.
12. Verdonk RC, Buis CI, van der Jagt EJ, Gouw AS, Limburg AJ, Slooff MJ, et al., Nonanastomotic biliary strictures after liver transplantation, part 2: management, outcome, and risk factors for disease progression. Liver Transpl 2007; 13: 725-732.
13. Guichelaar MM, Benson JT, Malinchoc M, Krom RA, Wiesner RH, Charlton MR,. Risk factors for and clinical course of nonanastomotic biliary strictures after liver transplantation. Am J Transplant 2003; 3: 885-890.
14. Ghinolfi D, Marti J, De Simone P, Lai Q, Pezzati D, Coletti L, et al., Use of octogenarian donors for liver transplantation: a survival analysis. Am J Transplant 2014; 14: 2062-2071.
15. Charlton M, Gane E, Manns MP, Brown RS Jr, Curry MP, Kwo PY, et al., Sofosbuvir and ribavirin for treatment of compensated recurrent hepatitis C virus infection after liver transplantation. Gastroenterology 2015; 148: 108-117.
16. Verhoeven CJ, Farid WR, de Ruiter PE, Hansen BE, Roest HP, de Jonge J, et al., MicroRNA profiles in graft preservation solution are predictive of ischemic-type biliary lesions after liver transplantation. J Hepatol 2013; 59: 1231-1238.
17. Nanni Costa A, Grossi P, Gianelli Castiglione A, Grigioni WF,; for Italian Transplant Research Network. Quality and safety in the Italian donor evaluation process. Transplantation 2008; 27 (suppl): S52-S56.
18. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, et al., Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22: 696-699.
19. Halldorson JB, Bakthavatsalam R, Fix O, Reyes JD, Perkins JD,. D-MELD, a simple predictor of post liver transplant mortality for optimization of donor/recipient matching. Am J Transplant 2009; 9: 318-326.
20. Dindo D, Demartines N, Clavien PA,. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004; 240: 205-213.
21. Paugam-Burtz C, Kavafyan J, Merckx P, Dahmani S, Sommacale D, Ramsay M, et al., Postreperfusion syndrome during liver transplantation for cirrhosis: outcome and predictors. Liver Transpl 2009; 15: 522-529.
22. Boggi U, Vistoli F, Del Chiaro M, Signori S, Pietrabissa A, Costa A, et al., A simplified technique for the en bloc procurement of abdominal organs that is suitable for pancreas and small bowel transplantation. Surgery 2004; 135: 629-641.
23. Cillo U, Burra P, Mazzaferro V, Belli L, Pinna AD, Spada M, et al.,; for I-BELT (Italian Board of Experts in the Field of LiverTransplantation). A multistep, consensus-based approach to organ allocation in liver transplantation: toward a "blended principle model." Am J Transplant 2015; 15: 2552-2561.
24. Freeman RB Jr, Gish RG, Harper A, Davis GL, Vierling J, Lieblein L, et al., Model for end-stage liver disease (MELD) exception guidelines: results and recommendations from the MELD exception study group and conference (MESSAGE) for the approval of patients who need liver transplantation with diseases not considered by the standard MELD formula. Liver Transpl 2006; 12 (suppl 3): S128-S136.
25. Gordon Burroughs S, Busuttil RW,. Optimal utilization of extended hepatic grafts. Surg Today 2009; 39: 746-751.
26. Anderson CD, Vachharajani N, Doyle M, Lowell JA, Wellen JR, Shenoy S, et al., Advanced donor age alone does not affect patient or graft survival after liver transplantation. J Am Coll Surg 2008; 207: 847-852.
27. Darius T, Monbaliu D, Jochmans I, Meurisse N, Desschans B, Coosemans W, et al., Septuagenarian and octogenarian donors provide excellent liver grafts for transplantation. Transplant Proc 2012; 44: 2861-2867.
28. Kim DY, Moon J, Island ER, Tekin A, Ganz S, Levi D, et al., Liver transplantation using elderly donors: a risk factor analysis. Clin Transplant 2011; 25: 270-276.
29. Gruttadauria S, Vizzini G, Biondo D, Mandalà L, Volpes R, Palazzo U, Gridelli B, et al., Critical use of extended criteria donor liver grafts in adult to adult whole liver transplantation: a single center experience. Liver Transpl 2008; 14: 220-227.
30. Cescon M, Grazi GL, Cucchetti A, Ravaioli M, Ercolani G, Vivarelli M, et al., Improving the outcome of liver transplantation with very old donors with updated selection and management criteria. Liver Transpl 2008; 14: 672-679.
31. Segev DL, Maley WR, Simpkins CE, Locke JE, Nguyen GC, Montgomery RA, Thuluvath PJ,. Minimizing risk associated with elderly donors by matching to preferred recipients. Hepatology 2007; 46: 1907-1918.
32. Mutimer DJ, Gunson B, Chen J, Berenguer J, Neuhaus P, Castaing D, et al., Impact of donor age and year of transplantation on graft and patient survival following liver transplantation for hepatitis C virus. Transplantation 2006; 81: 7-14.
33. Lee HW, Suh KS, Shin WY, Cho EH, Yi NJ, Lee JM, et al., Classification and prognosis of intrahepatic biliary stricture after liver transplantation. Liver Transpl 2007; 13: 1736-1742.
34. Cursio R, Gugenheim J,. Ischemia-reperfusion injury and ischemia-type biliary lesions following liver transplantation. J Transplant 2012; 2012: 164329.
35. op den Dries S, Westerkamp AC, Karimian N, Gouw AS, Bruinsma BG, Markmann JF, et al., Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures. J Hepatol 2014; 60: 1172-1179.
36. Karimian N, Op den Dries S, Porte RJ,. The origin of biliary strictures after liver transplantation: is it the amount of epithelial injury or insufficient regeneration that counts? J Hepatol 2013; 58: 1065-1067.
37. Axelrod DA, Lentine KL, Xiao H, Dzebisashvilli N, Schnitzler M, Tuttle-Newhall JE, Segev DL,. National assessment of early biliary complications following liver transplantation: incidence and outcomes. Liver Transpl 2014; 20: 446-456.
38. Sundaram V, Jones DT, Shah NH, de Vera ME, Fontes P, Marsh JW, et al., Posttransplant biliary complications in the pre- and post-model for end stage liver disease era. Liver Transpl 2011; 17: 428-435.
39. Williams ED, Draganov PV,. Endoscopic management of biliary strictures after liver transplantation. World J Gastroenterol 2009; 15: 3725-3733.
40. Albert JG, Filmann N, Elsner J, Moench C, Trojan J, Bojunga J, et al., Long-term follow-up of endoscopic therapy for stenosis of the bilio-biliary anastomosis associated with orthotopic liver transplantation. Liver Transpl 2013; 19: 586-593.
41. Zhu ZJ, Rao W, Sun JS, Cai JZ, Deng YL, Zheng H, et al., Liver retransplantation for ischemic type biliary lesions after orthotopic liver transplantation: a clinical report of 66 cases. Hepatobiliary Pancreat Dis Int 2008; 7: 471-475.
42. Zhang YC, Qu EZ, Ren J, Zhang Q, Zheng RQ, Yang Y, Chen GH,. New diagnosis and therapy model for ischemic-type biliary lesions following liver transplantation - a retrospective cohort study. Plos One 2014; 9: e105795.
43. Sharma S, Gurakar A, Jabbour N,. Biliary strictures following liver transplantation: past, present and preventive strategies. Liver Transpl 2008; 14: 759-769.
44. Knaak JM, Spetzler VN, Goldaracena N, Boehnert MU, Bazerbachi F, Louis KS, et al., Subnormothermic ex vivo liver perfusion reduces endothelial cell and bile duct injury after donation after cardiac death pig liver transplantation. Liver Transpl 2014; 20: 1296-1305.
45. Martins PN,. Normothermic machine preservation as an approach to decrease biliary complications of DCD liver grafts. Am J Transplant 2013; 13: 3287-3288.