Acinetobacter infections prevalence and frequency of the antibiotics resistance: Comparative study of intensive care units versus other hospital units

Pan African Medical Journal

Volumn 23, Issue , 2016, Pages

  Uwingabiye, Jean ^a,b   Frikh, Mohammed ^a,b   Lemnouer, Abdelhay ^a,b   Bssaibis, Fatna ^a,b   Belefquih, Bouchra ^a,b   Maleb, Adil ^a   Dahraoui, Souhail ^a,b   Belyamani, Lahcen ^a   Bait, Abdelouahed ^a   Haimeur, Charki ^a   Louzi, Lhoussain ^b   Ibrahimi, Azeddine ^b   Elouennass, Mostafa ^a,b  

^a MILITARY HOSPITAL MOHAMMED V   (Morocco)

^b MOHAMMED V UNIVERSITY   (Morocco)

Author keywords

Acinetobacter; Antibiotic resistance intensive care units; Prevalence

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CARBAPENEMASE; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; NETILMICIN; PIPERACILLIN PLUS TAZOBACTAM; RIFAMPICIN; TETRACYCLINE; TICARCILLIN; TIMENTIN; TOBRAMYCIN; ANTIINFECTIVE AGENT;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ACINETOBACTER LWOFFII; ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BLOOD CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GRAM NEGATIVE BACTERIUM; HOSPITAL PATIENT; HOSPITAL SUBDIVISIONS AND COMPONENTS; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MOROCCO; MULTIDRUG RESISTANCE; PREVALENCE; RESPIRATORY SYSTEM; RETROSPECTIVE STUDY; ACINETOBACTER INFECTIONS; ADOLESCENT; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; PUBLIC HOSPITAL; STATISTICS AND NUMERICAL DATA; TEACHING HOSPITAL; VERY ELDERLY; YOUNG ADULT;

ACINETOBACTER INFECTIONS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; HOSPITAL UNITS; HOSPITALS, MILITARY; HOSPITALS, TEACHING; HUMANS; INTENSIVE CARE UNITS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOROCCO; PREVALENCE; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84964702362     PISSN: None     EISSN: 19378688     Source Type: Journal    
DOI: 10.11604/pamj.2016.23.191.7915     Document Type: Article

References (35)

1. Obeidat N, Jawdat F, Al-Bakri AG, Shehabi AA. Major biologic characteristics of Acinetobacter baumannii isolates from hospital environmental and patients’ respiratory tract sources. Am J Infect Control. 2014; 42(4):401-4. PubMed | Google Scholar
2. Punpanich W, Nithitamsakun N, Treeratweeraphong V, Suntarattiwong P. Risk factors for carbapenem non-susceptibility and mortality in Acinetobacter baumannii bacteremia in children. Int J Infect Dis. 2012;16(11):e811-e815. PubMed | Google Scholar
3. Özgür ES, Horasan ES, Karaca K, Ersöz G, Atis S N, Kaya A. Ventilator-associated pneumonia due to extensive drug-resistant Acinetobacter baumannii: Risk factors, clinical features, and outcomes. Am J Infect Control. 2014; 42:206-8. PubMed | Google Scholar
4. Shields RK, Kwak EJ, Potoski BA, Doi Y, Adams-Haduch JM, Silviera FP, Toyoda Y, Pilewski JM, Crespo M, Pasculle AW, Clancy CJ, Nguyen MH. High mortality rates among solid organ transplant recipients infected with extensively drug-resistant Acinetobacter baumannii: using in vitro antibiotic combination testing to identify the combination of a carbapenem and colistin as an effective treatment regimen. Diagn Microbiol Infect Dis. 2011;70(2):246–252. PubMed | Google Scholar
5. Turkoglu M, Mirza E, Tunçcan OG, Erdem GU, Dizbay M, Yagci M, Aygencel G, Türköz Sucak G. Acinetobacter baumannii infection in patients with hematologic malignancies in intensive care unit: Risk factors and impact on mortality. J Crit Care. 2011; 26(5):460–467. PubMed | Google Scholar
6. Elouennass M, Sahnoun I, Zrara A, Bajjou T, Elhamzaoui S. Épidémiologie et profil de sensibilité des isolats d’hémoculture dans un unit de réanimation (2002–2005). Med Mal Infect. 2008; 38(1):18-24. PubMed | Google Scholar
7. Lahsoune M, Boutayeb H, Zerouali K, Belabbes H, El Mdaghri N. Prévalence et état de sensibilité aux antibiotiques d’Acinetobacter baumannii dans un CHU marocain. Med Mal Infect. 2007; 37:828–831. PubMed | Google Scholar
8. Ntusi NB, Badri M, Khalfey H, Whitelaw A, Oliver S, Piercy J, Raine R, Joubert I, Dheda K. ICU-Associated Acinetobacter baumannii Colonisation/Infection in a High HIV Prevalence Resource-Poor Setting. PLoS One. 2012; 7(12): e52452. PubMed | Google Scholar
9. Simor AE, Lee M, Vearncombe M, Jones-Paul L, Barry C, Gomez M, Fish JS, Cartotto RC, Palmer R, Louie M. An outbreak due to multirésistant Acinetobacter baumannii in burn unit: Risk factors for acquisition and management. Infect Control Hosp Epidemiol. 2002; 23 (5): 261-267. PubMed | Google Scholar
10. Vincent JL, Rello J, Marshall J, Silva E, Anzueto A, Martin CD, Moreno R, Lipman J, Gomersall C, Sakr Y, Reinhart K. EPIC II Group of Investigators.International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. JAMA. 2009;302(21):2323-2329. PubMed | Google Scholar
11. García-Garmendia JL, Ortiz-Leyba C, Garnacho-Montero J, Jiménez-Jiménez FJ, Pérez-Paredes C, Barrero-Almodóvar AE, Gili-Miner M. Risk Factors for Acinetobacter baumannii Nosocomial Bacteremia in Critically Ill Patients:a Cohort Study. Clin Infect Dis. 2001; 33(7):939–46. PubMed | Google Scholar
12. Shareek PS, Sureshkumar D, Ramgopalakrishnan, Ramasubramanian V, Ghafur KA, Thirunarayanan MA. Antibiotic Sensitivity Pattern of Blood Isolates of Acinetobacter Species in a Tertiary Care Hospital: A Retrospective Analysis. Am J Infect Dis. 2012; 8 (1): 65-69. PubMed | Google Scholar
13. Somily AM, Absar MM, Arshad MZ, Al Aska AI, Shakoor ZA, Fatani AJ, Siddiqui YM, Murray TS. Antimicrobial susceptibility patterns of multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii against carbapenems, colistin, and tigecycline. Saudi Med J. 2012; 33 (7): 750-755. PubMed| Google Scholar
14. Mushtaq S, Javeid I, Hassan M. Antibiotic sensitivity pattern of Acinetobacter species isolated from clinical specimens in a tertiary care hospital. Biomedica. 2013; 29:23-26. PubMed | Google Scholar
15. Gerald Denys A, Steven M Callister, Michael J Dowzicky. Antimicrobial susceptibility among gram-negative isolates collected in the USA between 2005 and 2011 as part of the Tigecycline Evaluation and Surveillance Trial (TEST). Ann Clin Microbiol Antimicrob. 2013; 12:24. PubMed | Google Scholar
16. Hamouche E, Sarkis DK. Évolution de la sensibilité aux antibiotiques de Escherichia coli,Klebsiella pneumoniae, Pseudomonas aeruginosa et Acinetobacter baumannii dans un CHU de Beyrouth entre 2005 et 2009. Pathol Biol (Paris). 2012; 60:e15-e20. PubMed | Google Scholar
17. Xu J, Sun Z, Li Y, Zhou Q. Surveillance and Correlation of Antibiotic Consumption and Resistance of Acinetobacter baumannii complex in a Tertiary Care Hospital in Northeast China, 2003–2011. Int J Environ Res Public Health. 2013;10:1462-1473. PubMed | Google Scholar
18. Al-Mously N, Hakawi A. Acinetobacter baumannii bloodstream infections in a tertiary hospital:Antimicrobial resistance surveillance. Int J Infect Control. 2013; 9 (2):1-8. PubMed | Google Scholar
19. Ben Haj Khalifa A, Khedher M. Profil de sensibilité aux antibiotiques des souches d’Acinetobacter baumannii isolées dans la région de Mahdia. Med Mal Infect. 2010; 40:126–128. PubMed | Google Scholar
20. Jaggi N, Sissodia P, Sharma L. Acinetobacter baumannii isolates in a tertiary care hospital: Antimicrobial resistance and clinical significance. J Microbiol Infect Dis. 2012; 2(2): 57-63. PubMed | Google Scholar
21. Queenan AM, Pillar CM, Deane J, Sahm DF, Lynch AS, Flamm RK, Peterson J, Davies TA. Multidrug resistance among Acinetobacter spp. in the USA and activity profile of key agents: results from Capital Surveillance 2010. Diagn Microbiol Infect Dis. 2012;73(3):267-70. PubMed | Google Scholar
22. Elouennass M, Bajou T, Lemnouer AH, Foissaud V, Hervé V, Baaj AJ. Acinetobacter baumannii: étude de la sensibilité des souches isolées à l’hôpital militaire d’instruction MohammedV, Rabat, Maroc. Med Mal Infect. 2003; 33:361–364. PubMed | Google Scholar
23. Garnacho-Montero J, Amaya-Villar R. Multiresistant Acinetobacter baumannii infections: epidemiology and management. Curr Opin Infect Dis. 2010; 23(4): 332-339. PubMed | Google Scholar
24. Huang CH, Lee CL, ACM Lin, Chen WY, Teng PC, Lee SH, Hsieh YJ, Jang TN. Different strains of Acinetobacter baumannii spreading in an intensive care unit. JACME. 2011;1:5-10. PubMed | Google Scholar
25. Fishbain J, Peleg AY. Treatment of Acinetobacter Infections. Clin Infect Dis. 2010; 51(1):79–84. PubMed | Google Scholar
26. Jung JY, Park MS, Kim SE, Park BH, Son JY, Kim EY, Lim JE, Lee SK, Lee SH, Lee KJ, Kang YA, Kim SK, Chang J, Kim YS. Risk factors for multi-drug resistant Acinetobacter baumannii bacteremia in patients with colonization in the intensive care unit. BMC Infect Dis 2010;10:228. Google Scholar
27. Nazmul MHM, Jamal H, Fazlul MKK. Acinetobacter species-associated infections and their antibiotic susceptibility profiles in Malaysia. Biomed Res-India. 2012; 23 (4): 571-575. PubMed | Google Scholar
28. Chang HC, Chen YC, Lin MC, Liu SF, Chung YH, Su MC, Fang WF, Tseng CC, Lie CH, Huang KT, Wang CC. Mortality risk factors in patients with Acinetobacter baumannii ventilator-associated pneumonia. J Formos Med Assoc. 2011;110(9):564-571. PubMed | Google Scholar
29. Chuang YC, Sheng WH, Li SY, Lin YC, Wang JT, Chen YC, Chang SC. Influence of genospecies of Acinetobacter baumannii complex on clinical outcomes of patients with Acinetobacter bacteremia. Clin Infect Dis. 2011; 52(3):352–60. PubMed | Google Scholar
30. Perez F, Hujer AM, Hujer KM, Decker BK, Rather PN, Bonomo RA. Global Challenge of Multidrug-Resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2007; 51(10):3471-84. PubMed | Google Scholar
31. Ziglam H, Elahmer O, Amri S, Shareef F, Grera A, Labeeb M, Zorgani A. Antimicrobial resistance patterns among Acinetobacter baumannii isolated from burn intensive care unit in Tripoli, Libya. IAJAA. 2012;2 (3):1-8. PubMed | Google Scholar
32. Shrestha M, Khanal B. Acinetobacter species: phenotypic characterization and antimicrobial resistance. JoNMC. 2013; 2(1):43-48. PubMed | Google Scholar
33. Ko KS, Suh JY, Kwon KT, Jung SI, Park KH, Kang CI, Chung DR, Peck KR, Song JH. High rates of resistance to colistin and Polymixin B in subgroups of Acinetobacter baumannii isolates from Korea. J Antimicrob Chemother. 2007; 60(5):1163-1167. PubMed | Google Scholar
34. Moffatt JH, Harper M, Harrison P, Hale JD, Vinogradov E, Seemann T, Henry R, Crane B, St Michael F, Cox AD, Adler B, Nation RL, Li J, Boyce JD. Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production. Antimicrob Agents Chemother. 2010; 4971–4977. PubMed | Google Scholar
35. Adams MD, Nickel GC, Bajaksouzian S, Lavender H, Murthy AR, Jacobs MR, Bonomo RA. Resistance to Colistin in Acinetobacter baumannii Associated with Mutations in the PmrAB Two-Component System. Antimicrob Agents Chemother. 2009; 53(9): 3628-3634. PubMed | Google Scholar