Maternal caffeine intake during pregnancy is associated with risk of low birth weight: A systematic review and dose-response meta-analysis

BMC Medicine

Volumn 12, Issue 1, 2014, Pages

  Chen, Ling Wei ^a   Wu, Yi ^a   Neelakantan, Nithya ^a   Chong, Mary Foong Fong ^b,c   Pan, An ^a,b   van Dam, Rob M ^a,b,d  

^a NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c AGENCY FOR SCIENCE   (Singapore)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Caffeine; Coffee; Intrauterine growth restriction; Low birth weight; Meta analysis; Small for gestational age; Systematic review

Indexed keywords

CAFFEINE;

ARTICLE; BIRTH WEIGHT; CAFFEINE INTAKE; DIETARY INTAKE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DOSE RESPONSE; HUMAN; LOW BIRTH WEIGHT; MATERNAL BEHAVIOR; OUTCOME ASSESSMENT; PREGNANCY; PREGNANCY OUTCOME; RISK ASSESSMENT; RISK FACTOR; SYSTEMATIC REVIEW; TREND STUDY; DRUG EFFECTS; FEMALE; MALE; META ANALYSIS; NEWBORN; PRENATAL EXPOSURE; PROSPECTIVE STUDY; RISK;

BIRTH WEIGHT; CAFFEINE; FEMALE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; MALE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROSPECTIVE STUDIES; RISK;

EID: 84964698249     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-014-0174-6     Document Type: Article

References (65)

1. Wardlaw TM, World Health Organization, UNICEF: Low Birthweight: Country, Regional and Global Estimates. Geneva; New York: WHO; UNICEF; 2004.
2. Lawn JE, Cousens S, Zupan J: 4 million neonatal deaths: When? Where? Why? Lancet 2005, 365:891-900.
3. Mcmillen IC: Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005, 85:571-633.
4. Maslova E, Bhattacharya S, Lin SW, Michels KB: Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. Am J Clin Nutr 2010, 92:1120-1132.
5. Eteng MU, Eyong EU, Akpanyung EO, Agiang MA, Aremu CY: Recent advances in caffeine and theobromine toxicities: a review. Plant Foods Hum Nutr 1997, 51:231-243.
6. CARE Study Group: Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. BMJ 2008, 337:a2332-a2332.
7. Arnaud MJ, Bracco I, Sauvageat JL, Clerc MF: Placental transfer of the major caffeine metabolite in the rat using 6-amino-5[N-formylmethylamino] 1,3[Me-14C]-dimethyluracil administered orally or intravenously to the pregnant rat. Toxicol Lett 1983, 16:271-279.
8. Aldridge A, Aranda JV, Neims AH: Caffeine metabolism in the newborn. Clin Pharmacol Ther 1979, 25:447-453.
9. Sengpiel V, Elind E, Bacelis J, Nilsson S, Grove J, Myhre R, Haugen M, Meltzer HM, Alexander J, Jacobsson B: Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med 2013, 11:42.
10. Knutti R, Rothweiler H, Schlatter C: The effect of pregnancy on the pharmacokinetics of caffeine. Arch Toxicol Suppl 1982, 5:187-192.
11. Brazier JL, Ritter J, Berland M, Khenfer D, Faucon G: Pharmacokinetics of caffeine during and after pregnancy. Dev Pharmacol Ther 1983, 6:315-322.
12. Bech BH: Coffee and fetal death: a cohort study with prospective data. Am J Epidemiol 2005, 162:983-990.
13. Kirkinen P, Jouppila P, Koivula A, Vuori J, Puukka M: The effect of caffeine on placental and fetal blood flow in human pregnancy. Am J Obstet Gynecol 1983, 147:939-942.
14. Frary CD, Johnson RK, Wang MQ: Food sources and intakes of caffeine in the diets of persons in the United States. J Am Diet Assoc 2005, 105:110-113.
15. Peck JD, Leviton A, Cowan LD: A review of the epidemiologic evidence concerning the reproductive health effects of caffeine consumption: a 2000-2009 update. Food Chem Toxicol 2010, 48:2549-2576.
16. Brent RL, Christian MS, Diener RM: Evaluation of the reproductive and developmental risks of caffeine. Birth Defects Res B Dev Reprod Toxicol 2011, 92:152-187.
17. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB, for the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) Group: Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 2000, 283:2008-2012.
18. Scopus S: Content Coverage Guide. Amsterdam, Netherlands: Elsevier BV; 2011.
19. Haram K, Søfteland E, Bukowski R: Intrauterine growth restriction. Int J Gynecol Obstet 2006, 93:5-12.
20. Suhag A, Berghella V: Intrauterine growth restriction (IUGR): etiology and diagnosis. Curr Obstet Gynecol Rep 2013, 2:102-111.
21. Sim J, Wright CC: The kappa statistic in reliability studies: use, interpretation, and sample size requirements. Phys Ther 2005, 85:257-268.
22. Thomas DC: Statistical Methods in Environmental Epidemiology. Oxford; New York: Oxford University Press; 2009.
23. Mills JL, Holmes LB, Aarons JH, Simpson JL, Brown ZA, Jovanovic-Peterson LG, Conley MR, Graubard BI, Knopp RH, Metzger BE: Moderate caffeine use and the risk of spontaneous abortion and intrauterine growth retardation. JAMA 1993, 269:593-597.
24. Bracken MB, Triche EW, Belanger K, Hellenbrand K, Leaderer BP: Association of maternal caffeine consumption with decrements in fetal growth. Am J Epidemiol 2003, 157:456-466.
25. Bakker R, Steegers EA, Obradov A, Raat H, Hofman A, Jaddoe VW: Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study. Am J Clin Nutr 2010, 91:1691-1698.
26. Larsson SC, Orsini N: Coffee consumption and risk of stroke: a dose-response meta-analysis of prospective studies. Am J Epidemiol 2011, 174:993-1001.
27. Olsen J, Overvad K, Frische G: Coffee consumption, birthweight, and reproductive failures. Epidemiology 1991, 2:370-374.
28. Spinillo A, Capuzzo E, Nicola SE, Colonna L, Egbe TO, Zara C: Factors potentiating the smoking-related risk of fetal growth retardation. Br J Obstet Gynaecol 1994, 101:954-958.
29. Bunker ML, McWilliams M: Caffeine content of common beverages. J Am Diet Assoc 1979, 74:28-32.
30. Martin TR, Bracken MB: The association between low birth weight and caffeine consumption during pregnancy. Am J Epidemiol 1987, 126:813-821.
31. Grosso LM, Rosenberg KD, Belanger K, Saftlas AF, Leaderer B, Bracken MB: Maternal caffeine intake and intrauterine growth retardation. Epidemiology 2001, 12:447-455.
32. Shu XO, Hatch MC, Mills J, Clemens J, Susser M: Maternal smoking, alcohol drinking, caffeine consumption, and fetal growth: results from a prospective study. Epidemiology 1995, 6:115-120.
33. Brooke OG, Anderson HR, Bland JM, Peacock JL, Stewart CM: Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress. BMJ 1989, 298:795-801.
34. Clausson B, Granath F, Ekbom A, Lundgren S, Nordmark A, Signorello LB, Cnattingius S: Effect of caffeine exposure during pregnancy on birth weight and gestational age. Am J Epidemiol 2002, 155:429-436.
35. Larroque B, Kaminski M, Lelong N, Subtil D, Dehaene P: Effects on birth weight of alcohol and caffeine consumption during pregnancy. Am J Epidemiol 1993, 137:941-950.
36. DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials 1986, 7:177-188.
37. Higgins JP, Thompson SG: Quantifying heterogeneity in a meta-analysis. Stat Med 2002, 21:1539-1558.
38. Higgins JP, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in meta-analyses. BMJ 2003, 327:557-560.
39. Greenland S, Longnecker MP: Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol 1992, 135:1301-1309.
40. Orsini N, Bellocco R, Greenland S: Generalized least squares for trend estimation of summarized dose-response data. Stata J 2006, 6:40-57.
41. Begg CB, Mazumdar M: Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50:1088-1101.
42. Egger M, Smith GD, Schneider M, Minder C: Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
43. Kuzma JW, Sokol RJ: Maternal drinking behavior and decreased intrauterine growth. Alcohol Clin Exp Res 1982, 6:396-402.
44. Fried PA, O'Connell CM: A comparison of the effects of prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth. Neurotoxicol Teratol 1987, 9:79-85.
45. Dar E, Kanarek MS, Anderson HA, Sonzogni WC: Fish consumption and reproductive outcomes in Green Bay, Wisconsin. Environ Res 1992, 59:189-201.
46. Committee on Toxicity: COT statement on the reproductive effects of caffeine. Lond Comm Toxic Chem Food Consum Prod Environ 2008. http://cot.food.gov.uk/cotstatements/cotstatementsyrs/cotstatements2008/cot200804.
47. Santos IS, Victora CG, Huttly S, Morris S: Caffeine intake and pregnancy outcomes: a meta-analytic review. Cad Saude Publica 1998, 14:523-530.
48. Fernandes O, Sabharwal M, Smiley T, Pastuszak A, Koren G, Einarson T: Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth: a meta-analysis. Reprod Toxicol 1998, 12:435-444.
49. Bech BH, Obel C, Henriksen TB, Olsen J: Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial. BMJ 2007, 334:409.
50. James JE, Bruce MS, Lader MH, Scott NR: Self-report reliability and symptomatology of habitual caffeine consumption. Br J Clin Pharmacol 1989, 27:507-514.
51. Grosso LM, Triche E, Benowitz NL, Bracken MB: Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake? Ann Epidemiol 2008, 18:172-178.
52. Cnattingius S, Signorello LB, Annerén G, Clausson B, Ekbom A, Ljunger E, Blot WJ, McLaughlin JK, Petersson G, Rane A, Granath F: Caffeine intake and the risk of first-trimester spontaneous abortion. N Engl J Med 2000, 343:1839-1845.
53. Heckman MA, Sherry K, De Mejia EG: Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr Rev Food Sci Food Saf 2010, 9:303-317.
54. Oddy WH, O'Sullivan TA: Energy drinks for children and adolescents. BMJ 2009, 339:b5268-b5268.
55. Derbyshire E, Abdula S: Habitual caffeine intake in women of childbearing age. J Hum Nutr Diet 2008, 21:159-164.
56. Knight CA, Knight I, Mitchell DC, Zepp JE: Beverage caffeine intake in US consumers and subpopulations of interest: estimates from the Share of Intake Panel survey. Food Chem Toxicol 2004, 42:1923-1930.
57. Kramer MS: Determinants of low birth weight: methodological assessment and meta-analysis. Bull World Health Organ 1987, 65:663-737.
58. Dietz PM, Homa D, England LJ, Burley K, Tong VT, Dube SR, Bernert JT: Estimates of nondisclosure of cigarette smoking among pregnant and nonpregnant women of reproductive age in the United States. Am J Epidemiol 2011, 173:355-359.
59. Boylan SM, Greenwood DC, Alwan N, Cooke MS, Dolby VA, Hay AW, Kirk SF, Konje JC, Potdar N, Shires S, Simpson NA, Taub N, Thomas JD, Walker JJ, White KL, Wild CP, Cade JE: Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction? Matern Child Health J 2013, 17:601-608.
60. Weathersbee PS, Lodge JR: Caffeine: its direct and indirect influence on reproduction. J Reprod Med 1977, 19:55-63.
61. Soyka LF: Effects of methylxanthines on the fetus. Clin Perinatol 1979, 6:37-51.
62. ACOG: Committee Opinion No. 462: moderate caffeine consumption during pregnancy. Obstet Gynecol 2010, 116:467-468.
63. Wang X, Tager IB, Vunakis HV, Speizer FE, Hanrahan JP: Maternal smoking during pregnancy, urine cotinine concentrations, and birth outcomes. A prospective cohort study. Int J Epidemiol 1997, 26:978-988.
64. Pollack H, Lantz PM, Frohna JG: Maternal smoking and adverse birth outcomes among singletons and twins. Am J Public Health 2000, 90:395-400.
65. Patra J, Bakker R, Irving H, Jaddoe V, Malini S, Rehm J: Dose-response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)-a systematic review and meta-analyses. Br J Obstet Gynaecol 2011, 118:1411-1421.