Procalcitonin-guided therapy for the initiation of antibiotics in the ED: A systematic review

American Journal of Emergency Medicine

Volumn 34, Issue 7, 2016, Pages 1286-1293

  Van Der Does, Yuri ^a   Rood, Pleunie P M ^a   Haagsma, Juanita A ^a   Patka, Peter ^a   Van Gorp, Eric C M ^a   Limper, Maarten ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PROCALCITONIN; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER; CALCITONIN;

ANTIBIOTIC THERAPY; ARTIFICIAL VENTILATION; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMMUNITY ACQUIRED PNEUMONIA; DISEASE EXACERBATION; EMERGENCY WARD; FEVER; HOSPITAL ADMISSION; HOSPITAL MORTALITY; HUMAN; INTENSIVE CARE UNIT; INTENTION TO TREAT ANALYSIS; LOWER RESPIRATORY TRACT INFECTION; MORTALITY RATE; MULTICENTER STUDY (TOPIC); PRESCRIPTION; PRIORITY JOURNAL; PROTOCOL COMPLIANCE; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY TRACT INFECTION; REVIEW; SYSTEMATIC REVIEW; ALGORITHM; BACTERIAL INFECTIONS; BLOOD; CLINICAL DECISION MAKING; HOSPITAL EMERGENCY SERVICE;

ALGORITHMS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BIOMARKERS; CALCITONIN; CLINICAL DECISION-MAKING; EMERGENCY SERVICE, HOSPITAL; HUMANS;

EID: 84964662741     PISSN: 07356757     EISSN: 15328171     Source Type: Journal    
DOI: 10.1016/j.ajem.2016.03.065     Document Type: Review

References (32)

1. R.P. Dellinger, M.M. Levy, A. Rhodes, D. Annane, H. Gerlach, S.M. Opal, and et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 Intensive Care Med 39 2 2013 165 228
2. S.E. Cosgrove, and Y. Carmeli The impact of antimicrobial resistance on health and economic outcomes Clin Infect Dis 36 11 2003 1433 1437
3. R. Laxminarayan, A. Duse, C. Wattal, A.K. Zaidi, H.F. Wertheim, N. Sumpradit, and et al. Antibiotic resistance - the need for global solutions Lancet Infect Dis 13 12 2013 1057 1098
4. T.P. Van Boeckel, S. Gandra, A. Ashok, Q. Caudron, B.T. Grenfell, S.A. Levin, and et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data Lancet Infect Dis 14 8 2014 742 750
5. B. Spellberg, J. Bartlett, R. Wunderink, and D.N. Gilbert Novel approaches are needed to develop tomorrow's antibacterial therapies Am J Respir Crit Care Med 191 2 2015 135 140
6. T.H. Dellit, R.C. Owens, J.E. McGowan Jr., D.N. Gerding, R.A. Weinstein, J.P. Burke, and et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship Clin Infect Dis 44 2 2007 159 177
7. M. Assicot, D. Gendrel, H. Carsin, J. Raymond, J. Guilbaud, and C. Bohuon High serum procalcitonin concentrations in patients with sepsis and infection Lancet 341 8844 1993 515 518
8. N.J. Soni, D.J. Samson, J.L. Galaydick, V. Vats, D.L. Pitrak, and N. Aronson Procalcitonin-guided antibiotic therapy Rockville (MD): Agency for Healthcare Research and Quality (US); Report No.: 12(13)-EHC124-EF 2012 Oct
9. S. Manzano, B. Bailey, J.B. Girodias, A. Galetto-Lacour, J. Cousineau, and E. Delvin Impact of procalcitonin on the management of children aged 1 to 36 months presenting with fever without source: a randomized controlled trial Am J Emerg Med 28 6 2010 647 653
10. L. Lacroix, S. Manzano, L. Vandertuin, F. Hugon, A. Galetto-Lacour, and A. Gervaix Impact of the lab-score on antibiotic prescription rate in children with fever without source: a randomized controlled trial PLoS One 9 12 2014
11. C.C. Lai, S.Y. Chen, C.Y. Wang, J.Y. Wang, C.P. Su, C.H. Liao, and et al. Diagnostic value of procalcitonin for bacterial infection in elderly patients in the emergency department J Am Geriatr Soc 58 3 2010 518 522
12. S. Bressan, B. Andreola, P. Zucchetta, G. Montini, M. Burei, G. Perilongo, and et al. Procalcitonin as a predictor of renal scarring in infants and young children Pediatr Nephrol 24 6 2009 1199 1204
13. M. Christ-Crain, D. Jaccard-Stolz, R. Bingisser, M.M. Gencay, P.R. Huber, M. Tamm, and et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial Lancet 363 9409 2004 600 607
14. M. Christ-Crain, D. Stolz, and R. Bingisser Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial Am J Respir Crit Care Med 174 1 2006 84 93.2006
15. L. Bouadma, C.E. Luyt, F. Tubach, C. Cracco, A. Alvarez, C. Schwebel, and et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial Lancet 375 9713 2010 463 474
16. M. Briel, P. Schuetz, B. Mueller, J. Young, U. Schild, C. Nusbaumer, and et al. Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care Arch Intern Med 168 18 2008 2000 2007 [discussion 7-8]
17. P. Schuetz, M. Christ-Crain, R. Thomann, C. Falconnier, M. Wolbers, I. Widmer, and et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial JAMA 302 10 2009 1059 1066
18. D. Moher, A. Liberati, J. Tetzlaff, D.G. Altman, and P. Group Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Ann Intern Med 151 4 2009 264 269 [W64]
19. A. Booth, M. Clarke, D. Ghersi, D. Moher, M. Petticrew, and L. Stewart An international registry of systematic-review protocols Lancet 377 9760 2011 108 109
20. P.F. Whiting, A.W. Rutjes, M.E. Westwood, S. Mallett, J.J. Deeks, J.B. Reitsma, and et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies Ann Intern Med 155 8 2011 529 536
21. D. Drozdov, S. Schwarz, A. Kutz, E. Grolimund, A.C. Rast, D. Steiner, and et al. Procalcitonin and pyuria-based algorithm reduces antibiotic use in urinary tract infections: a randomized controlled trial BMC Med 13 1 2015
22. D. Stolz, M. Christ-Grain, R. Bingisser, J. Leuppi, D. Miedinger, C. Muller, and et al. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy Chest 131 1 2007 9 19
23. J. Tang, W. Long, L. Yan, Y. Zhang, J. Xie, G. Lu, and et al. Procalcitonin guided antibiotic therapy of acute exacerbations of asthma: A randomized controlled trial BMC Infect Dis 13 1 2013
24. K.F. Schulz Subverting randomization in controlled trials JAMA 274 18 1995 1456 1458
25. W. Long, X. Deng, Y. Zhang, G. Lu, J. Xie, and J. Tang Procalcitonin guidance for reduction of antibiotic use in low-risk outpatients with community-acquired pneumonia Respirology 16 5 2011 819 824
26. G. Baer, P. Baumann, M. Buettcher, U. Heininger, G. Berthet, J. Schafer, and et al. Procalcitonin Guidance to Reduce Antibiotic Treatment of Lower Respiratory Tract Infection in Children and Adolescents (ProPAED): a randomized controlled trial PLoS One 8 8 2013
27. K.B. Kristoffersen, O.S. Sogaard, C. Wejse, F.T. Black, T. Greve, B. Tarp, and et al. Antibiotic treatment interruption of suspected lower respiratory tract infections based on a single procalcitonin measurement at hospital admission - a randomized trial Clin Microbiol Infect 15 5 2009 481 487
28. V. Nobre, S. Harbarth, J.D. Graf, P. Rohner, and J. Pugin Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial Am J Respir Crit Care Med 177 5 2008 498 505
29. E. de Jong, J.A. van Oers, A. Beishuizen, P. Vos, W.J. Vermeijden, L.E. Haas, and et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial Lancet Infect Dis 2016
30. D. Gilbert Serum procalcitonin levels: comment on "effectiveness and safety of procalcitonin-guided antibiotic therapy in lower respiratory tract infections in 'real life'" Arch Intern Med 172 9 2012 722 723
31. M. Stocker, W.C. Hop, and A.M. van Rossum Neonatal procalcitonin intervention study (NeoPInS): effect of procalcitonin-guided decision making on duration of antibiotic therapy in suspected neonatal early-onset sepsis: a multi-centre randomized superiority and non-inferiority intervention study BMC Pediatr 10 2010 89
32. L.S. Friedman, and E.D. Richter Relationship between conflicts of interest and research results J Gen Intern Med 19 1 2004 51 56