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Volumn 30, Issue 6, 2016, Pages 981-985

Pioglitazone (Actos) and bladder cancer: Legal system triumphs over the evidence

Author keywords

Actos; Bladder cancer; CVD; Legal system; Pioglitazine

Indexed keywords

PIOGLITAZONE; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT;

EID: 84964615083     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2016.04.004     Document Type: Review
Times cited : (16)

References (47)
  • 1
    • 84899080533 scopus 로고    scopus 로고
    • Favorable effects of insulin sensitizers pertinent to peripheral arterial disease in type 2 diabetes: Results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial
    • Althouse, A.D., Abbott, J.D., Sutton-Tyrrell, K., Forker, A.D., Lombardero, M.S., Buttron, L.V.,.. Brooks, M.M., for the BARI 2D STUDY GROUP. Favorable effects of insulin sensitizers pertinent to peripheral arterial disease in type 2 diabetes: Results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. Diabetes Care 37 (2014), 1346–1352.
    • (2014) Diabetes Care , vol.37 , pp. 1346-1352
    • Althouse, A.D.1    Abbott, J.D.2    Sutton-Tyrrell, K.3    Forker, A.D.4    Lombardero, M.S.5    Buttron, L.V.6    Brooks, M.M.7
  • 2
    • 84862684037 scopus 로고    scopus 로고
    • The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: Nested case–control study
    • Azoulay, L., Yin, H., Filin, K.B., Assayag, J., Majdan, A., Pollak, M.N.,.. Suissa, A.S., The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: Nested case–control study. BMJ, 244, 2012, e3645.
    • (2012) BMJ , vol.244 , pp. e3645
    • Azoulay, L.1    Yin, H.2    Filin, K.B.3    Assayag, J.4    Majdan, A.5    Pollak, M.N.6    Suissa, A.S.7
  • 5
    • 84859760984 scopus 로고    scopus 로고
    • Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus
    • Chang, C.-H., Lin, J.-W., Wu, L.-C., Lai, M.-S., Chuang, L.-M., Chan, E.A., Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus. Hepatology 55 (2012), 1462–1472.
    • (2012) Hepatology , vol.55 , pp. 1462-1472
    • Chang, C.-H.1    Lin, J.-W.2    Wu, L.-C.3    Lai, M.-S.4    Chuang, L.-M.5    Chan, E.A.6
  • 6
    • 57649213646 scopus 로고    scopus 로고
    • Impact of peripheral arterial disease in patients with diabetes-results from PROactive (PROactive 11)
    • Dormandy, J.A., Betteridge, D.J., Schernthaner, G., Pirags, V., Norgren, L., on behalf of the PROactive investigators. Impact of peripheral arterial disease in patients with diabetes-results from PROactive (PROactive 11). Atherosclerosis 202 (2009), 272–281.
    • (2009) Atherosclerosis , vol.202 , pp. 272-281
    • Dormandy, J.A.1    Betteridge, D.J.2    Schernthaner, G.3    Pirags, V.4    Norgren, L.5
  • 7
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 1 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomized controlled trial
    • Dormandy, J.A., Charbonnel, B., Eckland, D.J.A., Erdmann, E., Massi-Benedetti, M., Maules, I.K.,.. Smith U on behalf of the PROactive investigators, Secondary prevention of macrovascular events in patients with type 1 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomized controlled trial. Lancet 366 (2005), 1279–1289.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.A.3    Erdmann, E.4    Massi-Benedetti, M.5    Maules, I.K.6    Smith U on behalf of the PROactive investigators7
  • 8
    • 84981322985 scopus 로고    scopus 로고
    • (accessed November 11, ).
    • Drugs.com U.S. Sales statistics for Actos prescriptions. (accessed November 11, 2015).
    • (2015)
  • 9
    • 33847675510 scopus 로고    scopus 로고
    • The effect of pioglitazone on recurrent myocardial infarction in 2,445 patients with type 2 diabetes and previous myocardial infarction
    • Erdmann, E., Dormandy, J.A., Charbonnel, B., Massi-Benedetti, M., Moules, I.K., Skene, A.M., on behalf of the PROactive Investigators. The effect of pioglitazone on recurrent myocardial infarction in 2,445 patients with type 2 diabetes and previous myocardial infarction. Journal of the American College of Cardiology 49 (2007), 1772–1780.
    • (2007) Journal of the American College of Cardiology , vol.49 , pp. 1772-1780
    • Erdmann, E.1    Dormandy, J.A.2    Charbonnel, B.3    Massi-Benedetti, M.4    Moules, I.K.5    Skene, A.M.6
  • 10
    • 84957848154 scopus 로고    scopus 로고
    • Ten-year observational follow-up of PROactive: A randomized cardiovascular outcomes trial evaluating pioglitazone in type 2 diabetes
    • Erdmann, E., Harding, S., Perez, A., Ten-year observational follow-up of PROactive: A randomized cardiovascular outcomes trial evaluating pioglitazone in type 2 diabetes. Diabetes, Obesity & Metabolism 18 (2016), 266–273.
    • (2016) Diabetes, Obesity & Metabolism , vol.18 , pp. 266-273
    • Erdmann, E.1    Harding, S.2    Perez, A.3
  • 12
    • 84937733175 scopus 로고    scopus 로고
    • Effect of pioglitazone medication on the incidence of dementia
    • Heneka, M.T., Fink, A., Doblhammer, G., Effect of pioglitazone medication on the incidence of dementia. Annals of Neurology 78 (2015), 284–294.
    • (2015) Annals of Neurology , vol.78 , pp. 284-294
    • Heneka, M.T.1    Fink, A.2    Doblhammer, G.3
  • 13
    • 84881157625 scopus 로고    scopus 로고
    • Risk of bladder cancer in diabetic patients treated with rosiglitazone or pioglitazone: A nested case–control study
    • Hsiao, F.-Y., Hsieh, P.-H., Huang, W.-F., Tsai, Y.-W., Gau, C.-S., Risk of bladder cancer in diabetic patients treated with rosiglitazone or pioglitazone: A nested case–control study. Drug Safety 36 (2013), 643–649.
    • (2013) Drug Safety , vol.36 , pp. 643-649
    • Hsiao, F.-Y.1    Hsieh, P.-H.2    Huang, W.-F.3    Tsai, Y.-W.4    Gau, C.-S.5
  • 14
    • 84981316030 scopus 로고    scopus 로고
    • (accessed November 15, 2015)
    • http://www.fda.gov/Drugs/DrugSafety/ucm226214.htm (accessed November 15, 2015).
  • 15
    • 84907665163 scopus 로고    scopus 로고
    • Risk of bladder cancer among patients with diabetes treated with a 15 mg pioglitazone dose in Korea: A multi-center retrospective cohort study
    • Jin, S.-M., Song, S.O., Jung, C.H., Chang, J.-S., Suh, S., Kang, S.M.,.. Lee, B-W., Risk of bladder cancer among patients with diabetes treated with a 15 mg pioglitazone dose in Korea: A multi-center retrospective cohort study. Journal of Korean Medical Science 29 (2014), 238–242.
    • (2014) Journal of Korean Medical Science , vol.29 , pp. 238-242
    • Jin, S.-M.1    Song, S.O.2    Jung, C.H.3    Chang, J.-S.4    Suh, S.5    Kang, S.M.6    Lee, B.-W.7
  • 18
    • 84897487863 scopus 로고    scopus 로고
    • The association of pioglitazone and urinary tract disease in type 2 diabetic Taiwanese; bladder cancer and chronic kidney
    • Lee, M.-Y., Hsiao, P.-J., Yang, Y.-H., Lin, K.-D., Shin, S.-J., The association of pioglitazone and urinary tract disease in type 2 diabetic Taiwanese; bladder cancer and chronic kidney. PLoS One, 9, 2014, e85479.
    • (2014) PLoS One , vol.9 , pp. e85479
    • Lee, M.-Y.1    Hsiao, P.-J.2    Yang, Y.-H.3    Lin, K.-D.4    Shin, S.-J.5
  • 19
    • 84924662049 scopus 로고    scopus 로고
    • Pioglitazone and bladder cancer risk: A multipopulation pooled, cumulative exposure analysis
    • on behalf of the Scottish Diabetes Research Network Epidemiology Group and the Diabetes and Cancer Research Consortium
    • Levin, D., Bell, S., Sund, R., Hartikainen, S.A., Tuomilehto, J., Pukkala, E.,.. Colhoun H.M. on behalf of the Scottish Diabetes Research Network Epidemiology Group and the Diabetes and Cancer Research Consortium, Pioglitazone and bladder cancer risk: A multipopulation pooled, cumulative exposure analysis. Diabetologia 58 (2015), 493–504.
    • (2015) Diabetologia , vol.58 , pp. 493-504
    • Levin, D.1    Bell, S.2    Sund, R.3    Hartikainen, S.A.4    Tuomilehto, J.5    Pukkala, E.6    Colhoun, H.M.7
  • 20
    • 79956217900 scopus 로고    scopus 로고
    • Risk of bladder cancer among diabetic patients treated with pioglitazone: Interim report of a longitudinal cohort study
    • Lewis, J.D., Ferrara, A., Peng, T., Hedderson, M., Bilker, W.B., Quesenberry, C.P.,.. Strom, B.L., Risk of bladder cancer among diabetic patients treated with pioglitazone: Interim report of a longitudinal cohort study. Diabetes Care 34 (2011), 916–922.
    • (2011) Diabetes Care , vol.34 , pp. 916-922
    • Lewis, J.D.1    Ferrara, A.2    Peng, T.3    Hedderson, M.4    Bilker, W.B.5    Quesenberry, C.P.6    Strom, B.L.7
  • 21
    • 84938364689 scopus 로고    scopus 로고
    • Pioglitazone use and risk of bladder cancer and other common cancers in persons with diabetes
    • Lewis, J.D., Habel, L.A., Quesenberry, C.P., Strom, B.L., Peng, T., Hedderson, M.M., Ferrara, A., Pioglitazone use and risk of bladder cancer and other common cancers in persons with diabetes. JAMA 314 (2015), 265–277.
    • (2015) JAMA , vol.314 , pp. 265-277
    • Lewis, J.D.1    Habel, L.A.2    Quesenberry, C.P.3    Strom, B.L.4    Peng, T.5    Hedderson, M.M.6    Ferrara, A.7
  • 22
    • 84904192577 scopus 로고    scopus 로고
    • Dose effect of thiazolidinedione on cancer risk in type 2 diabetes mellitus patients: A six-year population-based study
    • Lin, H.C., Hsu, Y.T., Kachingwe, B.H., Hsu, C.Y., Uang, Y.S., Wang, L.H., Dose effect of thiazolidinedione on cancer risk in type 2 diabetes mellitus patients: A six-year population-based study. Journal of Clinical Pharmacy and Therapeutics 39 (2014), 354–360.
    • (2014) Journal of Clinical Pharmacy and Therapeutics , vol.39 , pp. 354-360
    • Lin, H.C.1    Hsu, Y.T.2    Kachingwe, B.H.3    Hsu, C.Y.4    Uang, Y.S.5    Wang, L.H.6
  • 23
    • 34548590934 scopus 로고    scopus 로고
    • Pioglitazone and risk of cardiovascular events in patient with type 2 diabetes mellitus: A meta-analysis of randomized trials
    • Lincoff, A.M., Wolski, K., Nicholls, S.J., Nissen, S.E., Pioglitazone and risk of cardiovascular events in patient with type 2 diabetes mellitus: A meta-analysis of randomized trials. JAMA 298 (2007), 1180–1188.
    • (2007) JAMA , vol.298 , pp. 1180-1188
    • Lincoff, A.M.1    Wolski, K.2    Nicholls, S.J.3    Nissen, S.E.4
  • 25
    • 53349153475 scopus 로고    scopus 로고
    • Pioglitzone and cardiovascular risk: A comprehensive meta-analysis of randomized clinical trials
    • Mannucci, E., Monami, M., Lamanna, C., Gensini, G.F.,.. Marchionni, N., Pioglitzone and cardiovascular risk: A comprehensive meta-analysis of randomized clinical trials. Diabetes, Obesity & Metabolism 10 (2008), 1221–1238.
    • (2008) Diabetes, Obesity & Metabolism , vol.10 , pp. 1221-1238
    • Mannucci, E.1    Monami, M.2    Lamanna, C.3    Gensini, G.F.4    Marchionni, N.5
  • 26
    • 33845400193 scopus 로고    scopus 로고
    • Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: A randomized trial
    • Mazzone, T., Meyer, P.M., Feinstein, S.B., Davidson, M.H., Kondos, G.T., D'Agostino, R.B.,.. Haffner, S.M., Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: A randomized trial. JAMA 296 (2006), 2572–2581.
    • (2006) JAMA , vol.296 , pp. 2572-2581
    • Mazzone, T.1    Meyer, P.M.2    Feinstein, S.B.3    Davidson, M.H.4    Kondos, G.T.5    D'Agostino, R.B.6    Haffner, S.M.7
  • 27
    • 84866358522 scopus 로고    scopus 로고
    • Pioglitazone and risk of bladder cancer among diabetic patients in France: A population-based study
    • Neumann, A., Weill, A., Ricordeau, P., Fagot, J.P., Alla, F., Allemand, H., Pioglitazone and risk of bladder cancer among diabetic patients in France: A population-based study. Diabetologia 55 (2012), 1953–1962.
    • (2012) Diabetologia , vol.55 , pp. 1953-1962
    • Neumann, A.1    Weill, A.2    Ricordeau, P.3    Fagot, J.P.4    Alla, F.5    Allemand, H.6
  • 28
    • 41649084422 scopus 로고    scopus 로고
    • Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial
    • Nissen, S.E., Nicholls, S.J., Wolski, K., Nesto, R., Kupfer, S., Perez, A.,.. Tuzcu E.M.: PERISCOPE, Investigators. Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial. JAMA 299 (2008), 1561–1573.
    • (2008) JAMA , vol.299 , pp. 1561-1573
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3    Nesto, R.4    Kupfer, S.5    Perez, A.6    Tuzcu E.M.: PERISCOPE7
  • 29
    • 84981315712 scopus 로고    scopus 로고
    • (accessed November 15, 2015)
    • http://www.nytimes.com/2015/04/29/business/takeda-agrees-to-pay-2-4-billion-to-settle-suits-over-cancer-risk-of-actos.html (accessed November 15, 2015).
  • 31
    • 79953000587 scopus 로고    scopus 로고
    • Role of pioglitazone in the prevention of restenosis and need for revascularization after bare-metal stent implantation: A meta-analysis
    • Patel, D., Walitt, B., Lindsay, J., Wilensky, R.L., Role of pioglitazone in the prevention of restenosis and need for revascularization after bare-metal stent implantation: A meta-analysis. JACC. Cardiovascular Interventions 4 (2011), 353–360.
    • (2011) JACC. Cardiovascular Interventions , vol.4 , pp. 353-360
    • Patel, D.1    Walitt, B.2    Lindsay, J.3    Wilensky, R.L.4
  • 32
    • 84871607538 scopus 로고    scopus 로고
    • Pioglitazone and risk of bladder cancer: Clarification of the design of the French study
    • Perez, A.T., Pioglitazone and risk of bladder cancer: Clarification of the design of the French study. Diabetologia, 56, 2013, 227.
    • (2013) Diabetologia , vol.56 , pp. 227
    • Perez, A.T.1
  • 33
    • 84922674097 scopus 로고    scopus 로고
    • Pioglitazone has a dubious bladder cancer risk but an undoubted cardiovascular benefit
    • Ryder, R.E.J., Pioglitazone has a dubious bladder cancer risk but an undoubted cardiovascular benefit. Diabetic Medicine 32 (2014), 305–313.
    • (2014) Diabetic Medicine , vol.32 , pp. 305-313
    • Ryder, R.E.J.1
  • 34
    • 84863035912 scopus 로고    scopus 로고
    • SEER Cancer Statistics Factsheets: Bladder Cancer
    • National Cancer Institute. Bethesda, MD, (.
    • SEER Cancer Statistics Factsheets: Bladder Cancer, National Cancer Institute. Bethesda, MD, ( http://seer.cancer.gov/stafacts/html/urinb.html).
  • 37
    • 33746398045 scopus 로고    scopus 로고
    • Comparison of the glycemic effects of rosiglitazone and pioglitazone in triple oral therapy in type 2 diabetes mellitus
    • Tran, M.T., Navar, M.D., Davidson, M.B., Comparison of the glycemic effects of rosiglitazone and pioglitazone in triple oral therapy in type 2 diabetes mellitus. Diabetes Care 29 (2006), 1395–1396.
    • (2006) Diabetes Care , vol.29 , pp. 1395-1396
    • Tran, M.T.1    Navar, M.D.2    Davidson, M.B.3
  • 38
    • 79960915935 scopus 로고    scopus 로고
    • Diabetes and risk of bladder cancer: A study using the National Health Insurance database in Taiwan
    • Tseng, C.-H., Diabetes and risk of bladder cancer: A study using the National Health Insurance database in Taiwan. Diabetologia 54 (2011), 2009–2015.
    • (2011) Diabetologia , vol.54 , pp. 2009-2015
    • Tseng, C.-H.1
  • 39
    • 84859053613 scopus 로고    scopus 로고
    • Pioglitazone and bladder cancer: A population-based study of Taiwanese
    • Tseng, C.-H., Pioglitazone and bladder cancer: A population-based study of Taiwanese. Diabetes Care 35 (2012), 278–280.
    • (2012) Diabetes Care , vol.35 , pp. 278-280
    • Tseng, C.-H.1
  • 40
    • 84860117993 scopus 로고    scopus 로고
    • Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: Retrospective cohort study using UK general practice research database
    • Tzoulaki, J., Molokhia, M., Curcin, V., Little, M.P., Millett, C.J., Ng, A.,.. Elliott, P., Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: Retrospective cohort study using UK general practice research database. BMJ, 339, 2009, b4731.
    • (2009) BMJ , vol.339 , pp. b4731
    • Tzoulaki, J.1    Molokhia, M.2    Curcin, V.3    Little, M.P.4    Millett, C.J.5    Ng, A.6    Elliott, P.7
  • 41
    • 0028817815 scopus 로고
    • Overview of 6 years of type II diabetes: A progressive disease
    • U.K. Prospective Diabetes Study Group, Overview of 6 years of type II diabetes: A progressive disease. Diabetes 44 (1995), 1249–1258.
    • (1995) Diabetes , vol.44 , pp. 1249-1258
    • U.K. Prospective Diabetes Study Group1
  • 42
    • 84883223326 scopus 로고    scopus 로고
    • Comparing piolgitazone to insulin with respect to cancer, cardiovascular and bone fractures endpoints, using propensity score weights
    • Vallarino, C., Perez, A., Fusco, G., Liang, H., Bron, M., Manne, S.,.. Yu, S., Comparing piolgitazone to insulin with respect to cancer, cardiovascular and bone fractures endpoints, using propensity score weights. Clinical Drug Investigation 33 (2013), 621–631.
    • (2013) Clinical Drug Investigation , vol.33 , pp. 621-631
    • Vallarino, C.1    Perez, A.2    Fusco, G.3    Liang, H.4    Bron, M.5    Manne, S.6    Yu, S.7
  • 43
    • 84871113059 scopus 로고    scopus 로고
    • Pioglitazone and bladder cancer: A propensity score matched cohort study
    • Wei, L., Pioglitazone and bladder cancer: A propensity score matched cohort study. British Journal of Clinical Pharmacology 75 (2012), 254–259.
    • (2012) British Journal of Clinical Pharmacology , vol.75 , pp. 254-259
    • Wei, L.1
  • 45
    • 33947539408 scopus 로고    scopus 로고
    • Effects of pioglitazone in patients with type 2 diabetes with or without previous stroke: Results from PROactive (PROspective pioglitAzone Clinical Trial macroVascular Events 04)
    • Wilcox, R., Bousser, M.-G., Betteridge, J., Schernthaner, G., Kupfer, S., Dormandy, J., for the PROactive Investigators. Effects of pioglitazone in patients with type 2 diabetes with or without previous stroke: Results from PROactive (PROspective pioglitAzone Clinical Trial macroVascular Events 04). Stroke 38 (2007), 865–873.
    • (2007) Stroke , vol.38 , pp. 865-873
    • Wilcox, R.1    Bousser, M.-G.2    Betteridge, J.3    Schernthaner, G.4    Kupfer, S.5    Dormandy, J.6
  • 46
    • 84907994948 scopus 로고    scopus 로고
    • A comparison of all-cause mortality with pioglitazone and insulin in type 2 diabetes: An expanded analysis from a retrospective cohort study
    • Yang, J., Vallarino, C., Bron, M., Perez, A., Liang, H., Joseph, G.,.. Yu, S., A comparison of all-cause mortality with pioglitazone and insulin in type 2 diabetes: An expanded analysis from a retrospective cohort study. Current Medical Research and Opinion 30 (2014), 2223–2231.
    • (2014) Current Medical Research and Opinion , vol.30 , pp. 2223-2231
    • Yang, J.1    Vallarino, C.2    Bron, M.3    Perez, A.4    Liang, H.5    Joseph, G.6    Yu, S.7
  • 47
    • 84940786585 scopus 로고    scopus 로고
    • Pioglitazone treatment and cardiovascular event and death in subjects with type 2 diabetes without established cardiovascular disease (JDDM 36)
    • Yokoyama, H., Araki, S., Kawai, K., Oishi, M., A, H., Sugimoto, K., Sone, H.,.. Kashiwagi, A., on behalf of Japan Diabetes Clinical Data Management Study Group. Pioglitazone treatment and cardiovascular event and death in subjects with type 2 diabetes without established cardiovascular disease (JDDM 36). Diabetes Research and Clinical Practice 109 (2015), 485–492.
    • (2015) Diabetes Research and Clinical Practice , vol.109 , pp. 485-492
    • Yokoyama, H.1    Araki, S.2    Kawai, K.3    Oishi, M.4    A, H.5    Sugimoto, K.6    Sone, H.7    Kashiwagi, A.8


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