A novel method for deriving thresholds of toxicological concern for vaccine constituents

Toxicology Mechanisms and Methods

Volumn 26, Issue 4, 2016, Pages 270-275

  White, Jennifer ^a   Wrzesinski, Claudia ^b   Green, Martin ^b   Johnson, Giffe T ^a   McCluskey, James D ^a   Abritis, Alison ^a   Harbison, Raymond D ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Biologics; QSAR; TTCs; Vaccine safety

Indexed keywords

VACCINE; PHARMACEUTICAL VEHICLES AND ADDITIVES; PRESERVATIVE;

ADVERSE OUTCOME; ALGORITHM; ARTICLE; BENIGNI BOSSA ASSAY; CRAMER EXTENDED ASSAY; HUMAN; IN VIVO STUDY; LD50; MICRONUCLEUS TEST; PRIORITY JOURNAL; SOFTWARE; THRESHOLD OF TOXICOLOGICAL CONCERN; TOXICITY ASSAY; CHEMISTRY; DRUG CONTAMINATION; PROCEDURES; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THEORETICAL MODEL; TOXICOLOGY;

ADJUVANTS, PHARMACEUTIC; ALGORITHMS; DRUG CONTAMINATION; LETHAL DOSE 50; MODELS, THEORETICAL; PRESERVATIVES, PHARMACEUTICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE; TOXICOLOGY; VACCINES;

EID: 84964432640     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2016.1170250     Document Type: Article

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