Epidemiology of Hypertension in Canada: An Update

Canadian Journal of Cardiology

Volumn 32, Issue 5, 2016, Pages 687-694

  Padwal, Raj S ^a,b   Bienek, Asako ^c   McAlister, Finlay A ^a   Campbell, Norm R C ^d  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^d LIBIN CARDIOVASCULAR INSTITUTE OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ADULT; AGE DISTRIBUTION; ANTIHYPERTENSIVE THERAPY; ARTICLE; AWARENESS; BLOOD PRESSURE REGULATION; CANADA; CANADIAN; CARDIOVASCULAR MORTALITY; DIABETES MELLITUS; EPIDEMIOLOGICAL DATA; FEMALE; HEALTH SURVEY; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; POPULATION; PRESCRIPTION; PREVALENCE; SELF REPORT; TREND STUDY; AGED; BODY MASS; CLINICAL TRIAL; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; ECONOMICS; INDEPENDENT LIVING; MIDDLE AGED; MULTICENTER STUDY; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; ANTIHYPERTENSIVE AGENTS; BODY MASS INDEX; CANADA; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; HUMANS; HYPERTENSION; INDEPENDENT LIVING; MALE; MIDDLE AGED; PREVALENCE; RISK FACTORS;

EID: 84964316612     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2015.07.734     Document Type: Article

References (61)

1. World Health Organization A global brief on hypertension. Silent killer, global public health crisis 2013, Available at:, Accessed February 1, 2015. http://www.who.int/cardiovascular_diseases/publications/global_brief_hypertension/en.
2. Lim S.S., Vos T., Flaxman A.D., et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the global burden of disease study 2010. Lancet 2012, 380:2224-2260.
3. Haroun M., Jaar B.G., Hoffman S.C., et al. Risk factors for chronic kidney disease: a prospective study of 23,534 men and women in Washington County, Maryland. J Am Soc Nephrol 2003, 14:2934-2941.
4. Nagai M., Hoshide S., Kario K. Hypertension and dementia. Am J Hypertens 2009, 23:116-124.
5. Rapsomaniki R., Timmis A., George J., et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet 2014, 383:1899-1911.
6. Lewington S., Clarke R., Qizilbash N., et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002, 360:1903-1913. Prospective Studies Collaboration.
7. Lawes C.M., Vander Hoorn S., Rodgers A. Global burden of blood-pressure-related disease, 2001. Lancet 2008, 371:1513-1518. for the International Society of Hypertension.
8. Julius S., Nesbitt S.D., Egan B.M., et al. Feasibility of treating prehypertension with an angiotensin-receptor blocker. N Engl J Med 2006, 354:1685-1697.
9. Heidenreich P.A., Trogdon J.G., Khavjou O.A., et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation 2011, 123:933-944.
10. Weaver C.G., Clement F.M., Campbell N.R.C., et al. Healthcare costs attributable to hypertension. Hypertension 2015, 66:502-508.
11. Gaziano T.A., Bitton A., Anand S., Weinstein M.C. The global cost of nonoptimal blood pressure. J Hypertens 2009, 27:1472-1477.
12. Quan H., McAlister F.A., Khan N. The many faces of hypertension in Canada. Curr Opin Cardiol 2014, 29:354-359.
13. Statistics Canada Overview of the Canadian Health Measures Survey 2010, Available at:, Accessed May 20, 2015. http://www.statcan.gc.ca/imdb-bmdi/document/5071_D1_T9_V1-eng.pdf.
14. Tremblay M., Wolfson M., Connor Gorber S. Canadian Health Measures Survey: rationale, background and overview. Health Rep 2007, 18(suppl):7-20.
15. Bryan S., Saint-Pierre Larose M., Campbell N., Clarke J., Tremblay M. Resting blood pressure and heart rate measurement in the Canadian Health Measures Survey, cycle 1. Health Rep 2010, 21:1-8.
16. Statistics Canada. Canadian Community Health Survey 3.1 Overview. Available at:. Accessed February 15, 2015. http://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&SDDS=3226#a2.
17. Statistics Canada National Population Health Survey: household component, longitudinal (NPHS) 2012, Available at:, Accessed March 7, 2015. http://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&SDDS=3225.
18. Quan H., Smith M., Bartlett-Esquilant G., et al. Mining administrative health databases to advance medical science: geographical considerations and untapped potential in Canada. Can J Cardiol 2012, 28:152-154.
19. Quan H., Khan N., Hemmelgarn B.R., et al. Validation of a case definition to define hypertension using administrative data. Hypertension 2009, 54:1423-1428.
20. Statistics Canada Canadian Health Measures Survey (CHMS) data user guide: cycle 1 April 2011, Available at:, Accessed May 22, 2015. http://www.statcan.gc.ca/imdb-bmdi/document/5071_D2_T1_V1-eng.htm.
21. Rust K.F., Rao J.N.K. Variance estimation for complex surveys using replication techniques. Stat Methods Med Res 1996, 5:281-310.
22. Myers M.G. Eliminating the human factor in office blood pressure measurement. J Clin Hypertens 2014, 16:83-86.
23. McAlister F.A., Wilkins K., Joffres M., et al. Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades. CMAJ 2011, 183:1007-1013.
24. National Institute for Health and Clinical Excellence Type 2 diabetes: the management of type 2 diabetes May 2009, Available at:, Accessed May 22, 2015. http://www.nice.org.uk/guidance/cg87/chapter/1-recommendations#blood-pressure-therapy.
25. James P.A., Oparil S., Carter B.L., et al. 2014 Evidence-based guideline for the management of high blood pressure in adults. JAMA 2014, 311:507.
26. Joffres M., Falaschetti E., Gillespie C., et al. Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: a cross-sectional study. BMJ Open 2013, 3:e003423.
27. Guo F., He D., Zhang W., Walton R.G. Trends in prevalence, awareness, management, and control of hypertension among United States adults, 1999 to 2010. J Am Coll Cardiol 2012, 60:599-606.
28. Wang J., Zhang L., Wang F., Liu L., Wang H. Prevalence, awareness, treatment, and control of hypertension in China: results from a national survey. Am J Hypertens 2014, 27:1355-1361. for the China National Survey of Chronic Kidney Disease Working Group.
29. Twells L.K., Gregory D.M., Reddigan J., Midodzi W.K. Current and predicted prevalence of obesity in Canada: a trend analysis. CMAJ Open 2014, 2:E18-26.
30. Shields M., Carroll M., Ogden C. Adult obesity prevalence in Canada and the United States. NCHS Data Brief 2011, 56:1-8.
31. Statistics Canada. Distribution of the household population by adult body mass index (BMI) Health Canada (HC) classification, by sex and age group. Available at:. Accessed March 26, 2015. http://www5.statcan.gc.ca/cansim/a26?lang=eng&retrLang=eng&id=1170005&paSer=&pattern=&stByVal=1&p1=1&p2=-1&tabMode=dataTable&csid=
32. Bramlage P., Pittrow D., Wittchen H.-U., et al. Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. Am J Hypertens 2004, 17:904-910.
33. Padwal R.S., Sharma A.M. Prevention of cardiovascular disease: obesity, diabetes and the metabolic syndrome. Can J Cardiol 2010, 26(suppl C):18C-20C.
34. Padwal R.S. Obesity, diabetes, and the metabolic syndrome: the global scourge. Can J Cardiol 2014, 30:467-472.
35. Gortmaker S.L., Swinburn B.A., Levy D., et al. Changing the future of obesity: science, policy, and action. Lancet 2011, 378:838-847.
36. Swinburn B.A., Sacks G., Hall K.D., et al. The global obesity pandemic: shaped by global drivers and local environments. Lancet 2011, 378:804-814.
37. Employment and Social Development Canada Canadians in context-aging population August 2015, Available at:, Accessed March 7, 2015. http://www4.hrsdc.gc.ca/.3ndic.1t.4r@-eng.jsp?iid=33.
38. Sun Z. Aging, arterial stiffness, and hypertension. Hypertension 2014, 65:252-256.
39. Campbell N.R., Petrella R., Kaczorowski J. Public education on hypertension: a new initiative to improve the prevention, treatment and control of hypertension in Canada. Can J Cardiol 2006, 22:599-603.
40. Campbell N.R.C. Canada Chair in hypertension prevention and control: a pilot project. Can J Cardiol 2007, 23:557-560.
41. Onysko J., Maxwell C., Eliasziw M., et al. Large increases in hypertension diagnosis and treatment in Canada after a healthcare professional education program. Hypertension 2006, 48:853-860.
42. Campbell N.R.C., So L., Amankwah E., et al. Characteristics of hypertensive Canadians not receiving drug therapy. Can J Cardiol 2008, 24:485-490. for the Canadian Hypertension Education Program Outcomes Research Task Force.
43. Gee M.E., Bienek A., McAlister F.A., et al. Factors associated with lack of awareness and uncontrolled high blood pressure among Canadian adults with hypertension. Can J Cardiol 2012, 28:375-382.
44. Colley R.C., Garriguet D., Janssen I., et al. Physical activity of Canadian adults: accelerometer results from the 2007 to 2009 Canadian Health Measures Survey July 2014, Statistics Canada, Available at:, Accessed March 7, 2015. http://www.statcan.gc.ca/pub/82-003-x/2011001/article/11396-eng.htm.
45. Dasgupta K., Quinn R.R., Zarnke K.B., et al. The 2014 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol 2014, 30:485-501.
46. Health Canada Sodium in Canada June 2012, Available at:, Accessed March 7, 2015. http://www.hc-sc.gc.ca/fn-an/nutrition/sodium/index-eng.php.
47. Huffman M.D., Capewell S., Ning H., et al. Cardiovascular health behavior and health factor changes (1988-2008) and projections to 2020 results from the National Health and Nutrition Examination Surveys. Circulation 2012, 125:2595-2602.
48. Gee M.E., Janssen I., Pickett W., et al. Prevalence, awareness, treatment, and control of hypertension among Canadian adults with diabetes, 2007 to 2009. Can J Cardiol 2012, 28:367-374.
49. Ferrannini E., Cushman W.C. Diabetes and hypertension: the bad companions. Lancet 2012, 380:601-610.
50. Chen G., McAlister F.A., Walker R.L., Hemmelgarn B.R., Campbell N.R.C. Cardiovascular outcomes in Framingham participants with diabetes: the importance of blood pressure. Hypertension 2011, 57:891-897.
51. Tu K., Klein-Geltink J., Mitiku T.F., Mihai C., Martin J. De-identification of primary care electronic medical records free-text data in Ontario, Canada. BMC Med Inform Decis Mak 2010, 10:35.
52. Godwin M., Williamson T., Khan S., et al. Prevalence and management of hypertension in primary care practices with electronic medical records: a report from the Canadian Primary Care Sentinel Surveillance Network. CMAJ Open 2015, 3:E76-82.
53. Gupta M., Szmitko P., Singh N., et al. Contemporary management and control of uncomplicated hypertension in Canada: insight from the Primary Care Audit of Global Risk Management (PARADIGM) study. Can J Cardiol 2015, 31:664-670.
54. Campbell N.R., Brant R., Johansen H., et al. Increases in antihypertensive prescriptions and reductions in cardiovascular events in Canada. Hypertension 2009, 53:128-134.
55. Reaven G.M. Relationships among insulin resistance, type 2 diabetes, essential hypertension, and cardiovascular disease: similarities and differences. J Clin Hypertens 2011, 13:238-243.
56. McAlister F.A., Robitaille C., Gillespie C., et al. The impact of cardiovascular risk-factor profiles on blood pressure control rates in adults from Canada and the United States. Can J Cardiol 2013, 29:598-605.
57. Tobe S.W., Stone J.A., Walker K.M., et al. Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE): 2014 update. CMAJ 2014, 186:1299-1305.
58. Public Health Agency of Canada. 2009 tracking heart disease and stroke in Canada. Available at:. Accessed March 7, 2015. http://www.phac-aspc.gc.ca/publicat/2009/cvd-avc/index-eng.php.
59. Myers M.G., Godwin M., Dawes M., et al. Conventional versus automated measurement of blood pressure in primary care patients with systolic hypertension: randomised parallel design controlled trial. BMJ 2011, 342:d286.
60. Myers M.G., Valdivieso M., Kiss A. Use of automated office blood pressure measurement to reduce the white coat response. J Hypertens 2009, 27:280-286.
61. Peng M., Chen G., Lix L.M., et al. Refining hypertension surveillance to account for potentially misclassified cases. PLoS One 2015, 10:e0119186.