Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3 expression in a transcript-specific manner

BMC Genetics

Volumn 15, Issue 1, 2014, Pages

  Martin, Ruairidh I R ^a   Owens, W Andrew ^a,b   Cunnington, Michael S ^a,c   Mayosi, Bongani M ^d   Koref, Mauro Santibáñez ^a   Keavney, Bernard D ^a,e  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

^c HULL AND EAST YORKSHIRE HOSPITALS NHS TRUST   (United Kingdom)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Atrial fibrillation; Expression QTL mapping; Genome wide association study; Trans ethnic mapping

Indexed keywords

ADULT; AGED; ALLELE; ANCESTRY GROUP; ARTICLE; BRITISH CITIZEN; CARDIOVASCULAR DISEASE; CHROMOSOME 16Q; CONTROLLED STUDY; ENGLAND; EXON; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOME-WIDE ASSOCIATION STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICA; VERY ELDERLY; ZFHX3 GENE; ADOLESCENT; ATRIAL FIBRILLATION; CHROMOSOME 16; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; MUCOCUTANEOUS LYMPH NODE SYNDROME; QUANTITATIVE TRAIT LOCUS; TRANSCRIPTION INITIATION SITE; YOUNG ADULT;

HOMEODOMAIN PROTEIN; MESSENGER RNA; ZFHX3 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ATRIAL FIBRILLATION; CHROMOSOMES, HUMAN, PAIR 16; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HOMEODOMAIN PROTEINS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MUCOCUTANEOUS LYMPH NODE SYNDROME; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RNA, MESSENGER; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; YOUNG ADULT;

EID: 84964315276     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/s12863-014-0136-1     Document Type: Article

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