Pharmacokinetics of renally excreted drug dexpramipexole in subjects with impaired renal function

Journal of clinical pharmacology

Volumn 54, Issue 12, 2014, Pages 1383-1390

  He, Ping ^a   Kerr, Doug ^a   Marbury, Thomas ^a   Ries, Daniel ^a   Farwell, Wildon ^a   Stecher, Scott ^a   Dong, Yingwen ^a   Wei, Dong ^a   Rogge, Mark ^a  

^a PFIZER INC   (United States)

Author keywords

amyotrophic lateral sclerosis; dexpramipexole; eGFR; pharmacokinetics; renal impairment

Indexed keywords

BENZOTHIAZOLE DERIVATIVE; NEUROPROTECTIVE AGENT; PRAMIPEXOLE;

ADULT; AGED; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FAILURE; MALE; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL; URINE;

ADULT; AGED; BENZOTHIAZOLES; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; NEUROPROTECTIVE AGENTS; RENAL INSUFFICIENCY;

EID: 84964315065     PISSN: None     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.353     Document Type: Article

References (0)