A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency

Human molecular genetics

Volumn 23, Issue 19, 2014, Pages 5123-5132

  O'Reilly, Linda P ^a   Long, Olivia S ^a   Cobanoglu, Murat C ^a   Benson, Joshua A ^a   Luke, Cliff J ^a   Miedel, Mark T ^a   Hale, Pamela ^a   Perlmutter, David H ^a   Bahar, Ivet ^a   Silverman, Gary A ^a   Pak, Stephen C ^a  

^a Cell Biology and   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; PROTEIN BINDING;

ALPHA 1-ANTITRYPSIN DEFICIENCY; ANIMAL; BIOLOGY; CAENORHABDITIS ELEGANS; DISEASE MODEL; DRUG DEVELOPMENT; GENETIC ASSOCIATION; GENETICS; GENOMICS; HIGH THROUGHPUT SCREENING; HUMAN; MUTATION; PROTEOSTASIS DEFICIENCY; REPRODUCIBILITY; RNA INTERFERENCE;

ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANIMALS; CAENORHABDITIS ELEGANS; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MUTATION; PROTEIN BINDING; PROTEOSTASIS DEFICIENCIES; REPRODUCIBILITY OF RESULTS; RNA INTERFERENCE;

EID: 84964313883     PISSN: None     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu236     Document Type: Article

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