Effects of helminth co-infections on atopy, asthma and cytokine production in children living in a poor urban area in Latin America

BMC Research Notes

Volumn 7, Issue 1, 2014, Pages

  Alcantara Neves, Neuza Maria ^a   Britto, Gabriela De S G ^a   Veiga, Rafael Valente ^a   Figueiredo, Camila A ^a   Fiaccone, Rosimeire Leovigildo ^a   Da Conceição, Jackson S ^a   Cruz, Álvaro Augusto ^a   Rodrigues, Laura Cunha ^b   Cooper, Philip John ^c,d   Pontes De Carvalho, Lain C ^e   Barreto, Maurício Lima ^a  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DEL ECUADOR   (Ecuador)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^e INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Asthma; Atopy; Cytokines; Eosinophilia; Helminth infections; Total IgE; Treg cells

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; IMMUNOGLOBULIN E;

ANIMAL; ASTHMA; ATOPIC DERMATITIS; BIOLOGICAL MODEL; BIOSYNTHESIS; BLOOD; CHILD; CITY; COMPLICATION; EOSINOPHILIA; FEMALE; HELMINTH; HELMINTHIASIS; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; MALE; METABOLISM; MIXED INFECTION; MONONUCLEAR CELL; PARASITE; PARASITOLOGY; PHYSIOLOGY; POVERTY; PRESCHOOL CHILD; SKIN TEST; SOUTH AND CENTRAL AMERICA;

ANIMALS; ASTHMA; BIOMARKERS; CHILD; CHILD, PRESCHOOL; CITIES; COINFECTION; CYTOKINES; DERMATITIS, ATOPIC; EOSINOPHILIA; FEMALE; HELMINTHIASIS; HELMINTHS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; LATIN AMERICA; LEUKOCYTES, MONONUCLEAR; MALE; MODELS, BIOLOGICAL; PARASITES; POVERTY; SKIN TESTS;

EID: 84964312695     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-7-817     Document Type: Article

References (49)

1. Smits HH, Yazdanbakhsh M: Chronic helminth infections modulate allergen-specific immune responses: Protection against development of allergic disorders? Ann Med 2007, 39:428-439.
2. Cooper PJ, Chico ME, Guadalupe I, Sandoval CA, Mitre E, Platts-Mills TA, Barreto ML, Rodrigues LC, Strachan DP, Griffin GE: Impact of early life exposures to geohelminth infections on the development of vaccine immunity, allergic sensitization, and allergic inflammatory diseases in children living in tropical Ecuador: The ECUAVIDA birth cohort study. BMC Infect Dis 2011, 11:184.
3. van den Biggelaar AH, van Ree R, Rodrigues LC, Lell B, Deelder AM, Kremsner PG, Yazdanbakhsh M: Decreased atopy in children infected with Schistosoma haematobium: A role for parasite-induced interleukin-10. Lancet 2000, 356:1723-1727.
4. Araujo MI, Lopes AA, Medeiros M, Cruz AA, Sousa-Atta L, Sole D, Carvalho EM: Inverse association between skin response to aeroallergens and Schistosoma mansoni infection. Int Arch Allergy Immunol 2000, 123:145-148.
5. Medeiros M Jr, Figueiredo JP, Almeida MC, Matos MA, Araujo MI, Cruz AA, Atta AM, Rego MA, de Jesus AR, Taketomi EA, Carvalho EM: Schistosoma mansoni infection is associated with a reduced course of asthma. J Allergy Clin Immunol 2003, 111:947-951.
6. Bodammer P, Waitz G, Loebermann M, Holtfreter MC, Maletzki C, Krueger MR, Nizze H, Emmrich J, Reisinger EC: Schistosoma mansoni infection but not egg antigen promotes recovery from colitis in outbred NMRI mice. Dig Dis Sci 2011, 56:70-78.
7. Figueiredo CA, Barreto ML, Rodrigues LC, Cooper PJ, Silva NB, Amorim LD, Alcantara-Neves NM: Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network. Infect Immun 2010, 78:3160-3167.
8. Rodrigues LC, Newcombe PJ, Cunha SS, Alcantara-Neves NM, Genser B, Cruz AA, Simoes SM, Fiaccone R, Amorim L, Cooper PJ, Barreto ML: Early infection with Trichuris trichiura and allergen skin test reactivity in later childhood. Clin Exp Allergy 2008, 38:1769-1777.
9. Dagoye D, Bekele Z, Woldemichael K, Nida H, Yimam M, Hall A, Venn AJ, Britton JR, Hubbard R, Lewis SA: Wheezing, allergy, and parasite infection in children in urban and rural Ethiopia. Am J Respir Crit Care Med 2003, 167:1369-1373.
10. Cooper PJ, Chico ME, Bland M, Griffin GE, Nutman TB: Allergic symptoms, atopy, and geohelminth infections in a rural area of Ecuador. Am J Respir Crit Care Med 2003, 168:313-317.
11. Alcantara-Neves NM, Badaro SJ, dos Santos MC, Pontes-de-Carvalho L, Barreto ML: The presence of serum anti-Ascaris lumbricoides IgE antibodies and of Trichuris trichiura infection are risk factors for wheezing and/or atopy in preschool-Aged Brazilian children. Respir Res 2010, 11:114.
12. Feary J, Britton J, Leonardi-Bee J: Atopy and current intestinal parasite infection: A systematic review and meta-Analysis. Allergy 2011, 66:569-578.
13. Barreto ML, Genser B, Strina A, Teixeira MG, Assis AM, Rego RF, Teles CA, Prado MS, Matos S, Alcantara-Neves NM, Cairncross S: Impact of a citywide sanitation program in Northeast Brazil on intestinal parasites infection in young children. Environ Health Perspect 2010, 118:1637-1642.
14. Regis SC, Mendonca LR, Silva Ndos S, Dattoli VC, Alcantara-Neves NM, Barrouin-Melo SM: Seroprevalence and risk factors for canine toxocariasis by detection of specific IgG as a marker of infection in dogs from Salvador, Brazil. Acta Trop 2011, 120:46-51.
15. Dattoli VC, Freire SM, Mendonca LR, Santos PC, Meyer R, Alcantara-Neves NM: Toxocara canis infection is associated with eosinophilia and total IgE in blood donors from a large Brazilian centre. Trop Med Int Health 2011, 16:514-517.
16. Cooper PJ: Toxocara canis infection: An important and neglected environmental risk factor for asthma? Clin Exp Allergy 2008, 38:551-553.
17. Alcantara-Neves NM, Veiga RV, Dattoli VC, Fiaccone RL, Esquivel R, Cruz AA, Cooper PJ, Rodrigues LC, Barreto ML: The effect of single and multiple infections on atopy and wheezing in children. J Allergy Clin Immunol 2012, 129:359-367.
18. Mendonça LR, Veiga RV, Dattoli VC, Figueiredo CA, Fiaccone R, Santos J, Cruz AA, Rodrigues LC, Cooper PJ, Pontes-de-Carvalho LC, Barreto ML, Alcantara-Neves NM: Toxocara seropositivity, atopy and wheezing in children living in poor neighbourhoods in urban Latin American. PLoS Negl Trop Dis 2012, 6:e1886.
19. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet 1998, 351(9111):1225-1232. ISAAC 1998:1225-1232.
20. Leonardi-Bee J, Pritchard D, Britton J: Asthma and current intestinal parasite infection: systematic review and meta-Analysis. Am J Respir Crit Care Med 2006, 174:514-523.
21. Flohr C, Tuyen LN, Lewis S, Quinnell R, Minh TT, Liem HT, Campbell J, Pritchard D, Hien TT, Farrar J, Williams H, Britton J: Poor sanitation and helminth infection protect against skin sensitization in Vietnamese children: A cross-sectional study. J Allergy Clin Immunol 2006, 118(6):1305-1311.
22. Supali T, Djuardi Y, Wibowo H, van Ree R, Yazdanbakhsh M, Sartono E: Relationship between different species of helminths and atopy: A study in a population living in helminth-endemic area in Sulawesi, Indonesia. Int Arch Allergy Immunol 2010, 153:388-394.
23. Buijs J, Borsboom G, Renting M, Hilgersom WJ, van Wieringen JC, Jansen G, Neijens J: Relationship between allergic manifestations and Toxocara seropositivity: A cross-sectional study among elementary school children. Eur Respir J 1997, 10:1467-1475.
24. Li L, Gao W, Yang X, Wu D, Bi H, Zhang S, Huang M, Yao X: Asthma and toxocariasis. Ann Allergy Asthma Immunol 2014, 113(2):187-192.
25. Zacharasiewicz A, Auer H, Brath H, Stohlhofer B, Frank W, Aspock H: Zwick H: [Toxocara and bronchial hyperreactivity-results of a seroprevalence study]. Wien Klin Wochenschr 2000, 112:922-926.
26. Pearce EJ, MacDonald AS: The immunobiology of schistosomiasis. Nat Rev Immunol 2002, 2:499-511.
27. Cooper PJ, Barreto ML, Rodrigues LC: Human allergy and geohelminth infections: A review of the literature and a proposed conceptual model to guide the investigation of possible causal associations. Br Med Bull 2006, 79-80:203-218.
28. Matricardi PM, Rosmini F, Riondino S, Fortini M, Ferrigno L, Rapicetta M, Bonini S: Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study. BMJ 2000, 320:412-417.
29. Linneberg A, Ostergaard C, Tvede M, Andersen LP, Nielsen NH, Madsen F, Frolund L, Dirksen A, Jorgensen T: IgG antibodies against microorganisms and atopic disease in Danish adults: The Copenhagen Allergy Study. J Allergy Clin Immunol 2003, 111:847-853.
30. Janson C, Asbjornsdottir H, Birgisdottir A, Sigurjonsdottir RB, Gunnbjornsdottir M, Gislason D, Olafsson I, Cook E, Jogi R, Gislason T, Thjodleifsson B: The effect of infectious burden on the prevalence of atopy and respiratory allergies in Iceland, Estonia, and Sweden. J Allergy Clin Immunol 2007, 120:673-679.
31. Yazdanbakhsh M, van den Biggelaar A, Maizels RM: Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol 2001, 22:372-377.
32. Turner JD, Jackson JA, Faulkner H, Behnke J, Else KJ, Kamgno J, Boussinesq M, Bradley JE: Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness. J Infect Dis 2008, 197:1204-1212.
33. Lynch NR, Hagel I, Perez M, Di Prisco MC, Lopez R, Alvarez N: Effect of anthelmintic treatment on the allergic reactivity of children in a tropical slum. J Allergy Clin Immunol 1993, 92:404-411.
34. Mitre E, Norwood S, Nutman TB: Saturation of immunoglobulin E (IgE) binding sites by polyclonal IgE does not explain the protective effect of helminth infections against atopy. Infect Immun 2005, 73:4106-4111.
35. Wilson MS, Maizels RM: Regulation of allergy and autoimmunity in helminth infection. Clin Rev Allergy Immunol 2004, 26:35-50.
36. Correale J, Farez MF: The impact of environmental infections (parasites) on MS activity. Mult Scler 2011, 17:1162-1169.
37. Okada H, Kuhn C, Feillet H, Bach JF: The 'hygiene hypothesis' for autoimmune and allergic diseases: An update. Clin Exp Immunol 2010, 160:1-9.
38. Pontes-de-Carvalho L, Mengel J, Figueiredo CA, Social Changes A, Allergy in Latin America's Study G, Alcantara-Neves NM: Antigen mimicry between infectious agents and self or environmental antigens may lead to long-Term regulation of inflammation. Front Immunol 2013, 4:314.
39. Figueiredo CA, Alcantara-Neves NM, Veiga R, Amorim LD, Dattoli V, Mendonca LR, Junqueira S, Genser B, Santos M, de Carvalho LC, Cooper PJ, Rodrigues L, Barreto ML: Spontaneous cytokine production in children according to biological characteristics and environmental exposures. Environ Health Perspect 2009, 117:845-849.
40. Strachan DP: Hay fever, hygiene, and household size. BMJ 1989, 299:1259-1260.
41. Hagel I, Cabrera M, Hurtado MA, Sanchez P, Puccio F, Di Prisco MC, Palenque M: Infection by Ascaris lumbricoides and bronchial hyper reactivity: An outstanding association in Venezuelan school children from endemic areas. Acta Trop 2007, 103:231-241.
42. Cunha SSD, Barreto ML, Fiaccone RL, Cooper PJ, Alcantara-Neves NM, Simões SDM, Cruz ÁA, Rodrigues LC: Asthma cases in childhood attributed to atopy in tropical area in Brazil. Rev Panam Salud Publica 2010, 28:405-411.
43. Barreto ML, Cunha SS, Alcantara-Neves N, Carvalho LP, Cruz AA, Stein RT, Genser B, Cooper PJ, Rodrigues LC: Risk factors and immunological pathways for asthma and other allergic diseases in children: background and methodology of a longitudinal study in a large urban center in Northeastern Brazil (Salvador-SCAALA study). BMC Pulm Med 2006, 6:15.
44. Strina A, Cairncross S, Prado MS, Teles CA, Barreto ML: Childhood diarrhoea symptoms, management and duration: observations from a longitudinal community study. Trans R Soc Trop Med Hyg 2005, 99:407-416.
45. Katz N, Chaves A, Pellegrino J: A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 1972, 14:397-400.
46. de Savigny DHTI: Serodiagnosis of Toxocara larva migrans visceral. Can J Public Health 1975, 66:52-56.
47. Savigny DH: In vitro maintenance of Toxocara canis larvae and a simple method for the production of Toxocara ES antigen for use in serodiagnostic tests for visceral larva migrans. J Parasitol 1975, 61:781-782.
48. Kennedy MW, Maizels RM, Meghji M, Young L, Qureshi F, Smith HV: Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae. Parasite Immunol 1987, 9:407-420.
49. Barreto ML, Cunha SS, Fiaccone R, Esquivel R, Amorim LD, Alvim S, Prado M, Cruz AA, Cooper PJ, Santos DN, Strina A, Alcantara-Neves N, Rodrigues LC: Poverty, dirt, infections and non-Atopic wheezing in children from a Brazilian urban center. Respir Res 2010, 11:167.