Protective Effect of Naringenin Against Lipopolysaccharide-Induced Injury in Normal Human Bronchial Epithelium via Suppression of MAPK Signaling

Inflammation

Volumn 38, Issue 1, 2014, Pages 195-204

  Yu, Dan Hong ^a   Ma, Chun Hua ^b   Yue, Zhi Qiang ^c   Yao, Xin ^d   Mao, Chen Mei ^a  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

lipopolysaccharide; MAPK; naringenin; normal human bronchial epithelium

Indexed keywords

DRUG TOXICITY; FLAVANONE DERIVATIVE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN P65; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; NARINGENIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHARMACOLOGY; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHUS; BRONCHUS INJURY; BRONCHUS MUCOSA; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CLINICAL EVALUATION; CYTOKINE PRODUCTION; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFECTS; DRUG MECHANISM; ENZYMATIC DEGRADATION; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; INFLAMMATORY DISEASE; NORMAL HUMAN; NORMAL HUMAN BRONCHIAL EPITHELIUM INJURY; PHYSIOLOGY; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT MUCOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EFFECTS; ENZYMOLOGY; FLAVANONES; HUMANS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; PHARMACOLOGY; PHYSIOLOGY; RESPIRATORY MUCOSA; TOXICITY;

EID: 84964200364     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-0022-z     Document Type: Article

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