Impact of obstructive sleep apnoea on insulin resistance in nonobese and obese children

European Respiratory Journal

Volumn 47, Issue 4, 2016, Pages 1152-1161

  Koren, Dorit ^a   Gozal, David ^a   Philby, Mona F ^a   Bhattacharjee, Rakesh ^a,b   Kheirandish Gozal, Leila ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LIPOPROTEIN; GLUCOSE BLOOD LEVEL;

ANTHROPOMETRY; APNEA HYPOPNEA INDEX; ARTICLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE SEVERITY; DYSLIPIDEMIA; FEMALE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; OBESITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; POLYSOMNOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; REM SLEEP; RISK ASSESSMENT; SCHOOL CHILD; SLEEP DISORDERED BREATHING; SLEEP PATTERN; SLEEP TIME; SNORING; ANALYSIS; BLOOD; CHILDHOOD OBESITY; COMPLICATION; MULTIVARIATE ANALYSIS; ODDS RATIO;

ANTHROPOMETRY; BLOOD GLUCOSE; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INSULIN RESISTANCE; LIPOPROTEINS; MALE; MULTIVARIATE ANALYSIS; ODDS RATIO; PEDIATRIC OBESITY; POLYSOMNOGRAPHY; PROSPECTIVE STUDIES; SLEEP APNEA, OBSTRUCTIVE; SLEEP, REM; SNORING;

EID: 84964033225     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.01430-2015     Document Type: Article

References (41)

1. Ogden CL, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012; 307: 483-490.
2. Fagot-Campagna A, Pettitt DJ, Engelgau MM, et al. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr 2000; 136: 664-672.
3. Weiss R, Dziura J, Burgert TS, et al. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med 2004; 350: 2362-2374.
4. Juonala M, Magnussen CG, Berenson GS, et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med 2011; 365: 1876-1885.
5. Wing RR, Phelan S. Long-term weight loss maintenance. Am J Clin Nutr 2005; 82: Suppl., 222S-225S.
6. Young T, Skatrud J, Peppard PE. Risk factors for obstructive sleep apnea in adults. JAMA 2004; 291: 2013-2016.
7. Arens R, Muzumdar H. Childhood obesity and obstructive sleep apnea syndrome. J Appl Physiol 2010; 108: 436-444.
8. Canapari CA, Hoppin AG, Kinane TB, et al. Relationship between sleep apnea, fat distribution, and insulin resistance in obese children. J Clin Sleep Med 2011; 7: 268-273.
9. de la Eva RC, Baur LA, Donaghue KC, et al. Metabolic correlates with obstructive sleep apnea in obese subjects. J Pediatr 2002; 140: 654-659.
10. Tsaoussoglou M, Bixler EO, Calhoun S, et al. Sleep-disordered breathing in obese children is associated with prevalent excessive daytime sleepiness, inflammation, and metabolic abnormalities. J Clin Endocrinol Metab 2010; 95: 143-150.
11. Tauman R, O'Brien LM, Ivanenko A, et al. Obesity rather than severity of sleep-disordered breathing as the major determinant of insulin resistance and altered lipidemia in snoring children. Pediatrics 2005; 116: e66-e73.
12. Ogden CL, Kuczmarski RJ, Flegal KM, et al. Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version. Pediatrics 2002; 109: 45-60.
13. Barlow SE, Expert C. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007; 120: Suppl. 4, S164-S192.
14. American Academy of Sleep Medicine. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Westchester, American Academy of Sleep Medicine, 2007.
15. Ridker P, Rifai N, Cook NR, et al. Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA 2005; 294: 326-333.
16. Manninen V, Tenkanen L, Koskinen P, et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment. Circulation 1992; 85: 37-45.
17. Di Bonito P, Valerio G, Grugni G, et al. Comparison of non-HDL-cholesterol versus triglycerides-to-HDL-cholesterol ratio in relation to cardiometabolic risk factors and preclinical organ damage in overweight/obese children: The CARITALY study. Nutr Metab Cardiovasc Dis 2015; 25: 489-494.
18. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
19. Yeckel CW, Weiss R, Dziura J, et al. Validation of insulin sensitivity indices from oral glucose tolerance test parameters in obese children and adolescents. J Clin Endocrinol Metab 2004; 89: 1096-1101.
20. Madeira IR, Carvalho CN, Gazolla FM, et al. Ponto de corte do indice Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) avaliado pela curva Receiver Operating Characteristic (ROC) na deteccao de sindrome metabolica em criancas pre-puberes com excesso de peso. [Cut-off point for homeostatic model assessment for insulin resistance (HOMA-IR) index established from receiver operating characteristic (ROC) curve in the detection of metabolic syndrome in overweight pre-pubertal children.] Arq Bras Endocrinol Metab 2008; 52: 1466-1473.
21. Ascaso JF, Pardo S, Real JT, et al. Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism. Diabetes Care 2003; 26: 3320-3325.
22. Tauman R, O'Brien LM, Holbrook CR, et al. Sleep pressure score: A new index of sleep disruption in snoring children. Sleep 2004; 27: 274-278.
23. Koren D, Levitt Katz LE, Brar PC, et al. Sleep architecture and glucose and insulin homeostasis in obese adolescents. Diabetes Care 2011; 34: 2442-2447.
24. Grimaldi D, Beccuti G, Touma C, et al. Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications. Diabetes Care 2014; 37: 355-363.
25. Ip MS, Lam B, Ng MM, et al. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 2002; 165: 670-676.
26. Tasali E, Mokhlesi B, Van Cauter E. Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest 2008; 133: 496-506.
27. Babu AR, Herdegen J, Fogelfeld L, et al. Type 2 diabetes, glycemic control, and continuous positive airway pressure in obstructive sleep apnea. Arch Intern Med 2005; 165: 447-452.
28. Li AM, Chan MH, Chan DF, et al. Insulin and obstructive sleep apnea in obese Chinese children. Pediatr Pulmonol 2006; 41: 1175-1181.
29. Tauman R, O'Brien LM, Ivanenko A, et al. Obesity rather than severity of sleep-disordered breathing as the major determinant of insulin resistance and altered lipidemia in snoring children. Pediatrics 2005; 116: e66-e73.
30. Gozal D, Capdevila OS, Kheirandish-Gozal L. Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children. Am J Respir Crit Care Med 2008; 177: 1142-1149.
31. Kelly A, Dougherty S, Cucchiara A, et al. Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea. Sleep 2010; 33: 1185-1191.
32. Hannon TS, Lee S, Chakravorty S, et al. Sleep-disordered breathing in obese adolescents is associated with visceral adiposity and markers of insulin resistance. Int J Pediatr Obes 2011; 6: 157-160.
33. Goran MI, Ball GDC, Cruz ML. Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescents. J Clin Endocrinol Metab 2003; 88: 1417-1427.
34. Slyper AH. Childhood obesity, adipose tissue distribution, and the pediatric practitioner. Pediatrics 1998; 102: e4.
35. Dayyat E, Kheirandish-Gozal L, Gozal D. Childhood obstructive sleep apnea: one or two distinct disease entities? Sleep Med Clin 2007; 2: 433-444.
36. Matthews KA, Dahl RE, Owens JF, et al. Sleep duration and insulin resistance in healthy black and white adolescents. Sleep 2012; 35: 1353-1358.
37. Stamatakis KA, Punjabi NM. Effects of sleep fragmentation on glucose metabolism in normal subjects. Chest 2010; 137: 95-101.
38. Carreras A, Zhang SX, Peris E, et al. Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea. Int J Obes 2015; 39: 418-423.
39. Wang Y, Carreras A, Lee S, et al. Chronic sleep fragmentation promotes obesity in young adult mice. Obesity (Silver Spring) 2014; 22: 758-762.
40. Gharib SA, Khalyfa A, Abdelkarim A, et al. Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation. PLoS One 2012; 7: e37669.
41. Pepin JL, Guillot M, Tamisier R, et al. The upper airway resistance syndrome. Respiration 2012; 83: 559-566.