A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility

Cell

Volumn 165, Issue 2, 2016, Pages 317-330

  Vecchione, Loredana ^a   Gambino, Valentina ^a   Raaijmakers, Jonne ^a   Schlicker, Andreas ^a   Fumagalli, Arianna ^b   Russo, Mariangela ^c,d,e   Villanueva, Alberto ^f   Beerling, Evelyne ^b   Bartolini, Alice ^d   Mollevi, David G ^f   El Murr, Nizar ^g   Chiron, Marielle ^g   Calvet, Loreley ^g   Nicolazzi, Céline ^g   Combeau, Cécile ^g   Henry, Christophe ^g   Simon, Iris M ^h   Tian, Sun ^h   In 'T Veld, Sjors ^h   D'Ario, Giovanni ⁱ   Mainardi, Sara ^a   Beijersbergen, Roderick L ^a   Lieftink, Cor ^a   Linn, Sabine ^a   Rumpf Kienzl, Cornelia ^a   Delorenzi, Mauro ^i,j   Wessels, Lodewyk ^a   Salazar, Ramon ^k   Di Nicolantonio, Federica ^c,d   Bardelli, Alberto ^c,d   Van Rheenen, Jacco ^b   Medema, René H ^a   Tejpar, Sabine ^l   Bernards, René ^a   more..

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF TURIN   (Italy)

^d CANDIOLO CANCER INSTITUTE   (Italy)

^e FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^f HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^g SANOFI   (France)

^h Agendia NV   (Netherlands)

ⁱ SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^j UNIVERSITY OF LAUSANNE   (Switzerland)

^k BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^l UNIVERSITY HOSPITALS LEUVEN   (Belgium)

more..

Author keywords

BRAF like colon cancer; functional genomics; RANBP2; targeted treatment; vinorelbine

Indexed keywords

ALPHA TUBULIN; ANTINEOPLASTIC AGENT; B RAF KINASE; BEPRIDIL; CYCLIN B1; DM 4; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTONE H2B; K RAS PROTEIN; NAVELBINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; RANBP2 PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VINBLASTINE; CHAPERONE; NUCLEOPORIN; RAN-BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER REGRESSION; CELL DEATH; CENTROMERE; CENTROSOME; COLON CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; METAPHASE; MICROTUBULE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; CLASSIFICATION; COLONIC NEOPLASMS; DRUG EFFECTS; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELLS, CULTURED; COLONIC NEOPLASMS; HETEROGRAFTS; HUMANS; MICE; MICE, NUDE; MICROTUBULES; MOLECULAR CHAPERONES; NEOPLASM TRANSPLANTATION; NUCLEAR PORE COMPLEX PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; VINBLASTINE;

EID: 84963994913     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.02.059     Document Type: Article

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