Topical oil application and trans-epidermal water loss in preterm very low birth weight infants-a randomized trial

Journal of Tropical Pediatrics

Volumn 61, Issue 6, 2015, Pages 414-420

  Nangia, Sushma ^a   Paul, Vinod Kumar ^b   Deorari, Ashok Kumar ^b   Sreenivas, V ^b   Agarwal, Ramesh ^b   Chawla, Deepak ^c  

^a KALAWATI SARAN CHILDREN'S HOSPITAL   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c GOVERNMENT MEDICAL COLLEGE AND HOSPITAL   (India)

Author keywords

Coconut oil; Neonate; Prematurity; Skin conditioning score; Trans epidermal water loss; Very low birth weight

Indexed keywords

COCONUT OIL; EMOLLIENT AGENT; VEGETABLE OIL; WATER;

ARTICLE; BACTERIAL GROWTH; BIRTH WEIGHT; CONFIDENCE INTERVAL; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MEDICAL DEVICE; NEWBORN; PORTABLE CLOSED CHAMBER EVAPORIMETER; PREMATURITY; RANDOMIZED CONTROLLED TRIAL; SKIN WATER LOSS; VERY LOW BIRTH WEIGHT; CROSS INFECTION; DRUG EFFECTS; EPIDERMIS; FEMALE; GROWTH, DEVELOPMENT AND AGING; INDIA; INFANT, PREMATURE, DISEASES; INTRADERMAL DRUG ADMINISTRATION; MALE; METABOLISM; NEWBORN INTENSIVE CARE; SKIN CARE; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; CROSS INFECTION; EMOLLIENTS; EPIDERMIS; FEMALE; HUMANS; INDIA; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE UNITS, NEONATAL; MALE; PLANT OILS; SKIN CARE; TREATMENT OUTCOME; WATER;

EID: 84963825592     PISSN: 01426338     EISSN: 14653664     Source Type: Journal    
DOI: 10.1093/tropej/fmv049     Document Type: Article

References (15)

1. Evans NJ, Rutter N. Development of the epidermis in the newborn. Biol Neonate 1986;49:74-80.
2. Darmstadt GL, Mao-Qiang M, Chi E, et al. Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries. Acta Paediatr 2002;91:546-54.
3. Agren J, Sjors G, Sedin G. Transepidermal water loss in infants born at 24 and 25 weeks of gestation. Acta Paediatr 1998;87:1185-90.
4. Rutter N. The immature skin. Br Med Bull 1988;44:957-70.
5. Pabst RC, Starr KP, Qaiyumi S, et al. The effect of application of aquaphor on skin condition, fluid requirements, and bacterial colonization in very low birth weight infants. J Perinatol 1999;19:278-83.
6. Darmstadt GL, Dinulos JG. Neonatal skin care. Pediatr Clin North Am 2000;47:757-82.
7. Mullany LC, Darmstadt GL, Khatry SK, et al. Traditional massage of newborns in Nepal: implications for trials of improved practice. J Trop Pediatr 2005;51:82-6.
8. Vernon HJ, Lane AT, Wischerath LJ, et al. Semipermeable dressing and transepidermal water loss in premature infants. Pediatrics 1990;86:357-62.
9. Nopper AJ, Horii KA, Sookdeo-Drost S, et al. Topical ointment therapy benefits premature infants. J Pediatr 1996;128:660-69.
10. Edwards WH, Conner JM, Soll RF, et al. The effect of Aquaphor Original Emollient Ointment on nosocomial sepsis rates and skin integrity in infants of birth weight 501 to 1000 grams. Pediatr Res 2001;49:2330.
11. Lane AT, Drost SS. Effects of repeated application of emollient cream to premature neonates' skin. Pediatrics 1993;92:415-19.
12. Darmstadt GL, Badrawi N, Law PA, et al. Topically applied sunflower seed oil prevents invasive bacterial infections in preterm infants in Egypt: a randomized, controlled clinical trial. Pediatr Infect Dis J 2004;23:719-25.
13. Hammarlund K, Nilsson GE, Oberg PA, et al. Transepidermal water loss in newborn infants: V. Evaporation from the skin and heat exchange during the first hours of life. Acta Paediatr Scand 1980;69:385-92.
14. Rutter N, Hull D. Reduction of skin water loss in the new-born: I. Effect of applying topical agents. Arch Dis Child 1981;56:669-72.
15. Wananukul S, Praisuwanna P. Clear topical ointment decreases transepidermal water loss in jaundiced preterm infants receiving phototherapy. J Med Assoc Thai 2002;85:102-6.