Improved Monosynaptic Neural Circuit Tracing Using Engineered Rabies Virus Glycoproteins

Cell Reports

Volumn 15, Issue 4, 2016, Pages 692-699

  Kim, Euiseok J ^a   Jacobs, Matthew W ^a   Ito Cole, Tony ^a   Callaway, Edward M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; PROTEIN VARIANT; VIRUS GLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENETIC COMPLEMENTATION; MONOSYNAPTIC PATHWAY; MOUSE; NERVE CELL NETWORK; NEUROANATOMICAL TRACT TRACING; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN ENGINEERING; RABIES VIRUS; VIRUS STRAIN;

EID: 84963589320     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.03.067     Document Type: Article

References (26)

1. Callaway E.M. Transneuronal circuit tracing with neurotropic viruses. Curr. Opin. Neurobiol. 2008, 18:617-623.
2. Callaway E.M., Luo L. Monosynaptic circuit tracing with glycoprotein-deleted rabies viruses. J. Neurosci. 2015, 35:8979-8985.
3. Gerfen C.R., Paletzki R., Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron 2013, 80:1368-1383.
4. Hippenmeyer S., Vrieseling E., Sigrist M., Portmann T., Laengle C., Ladle D.R., Arber S. A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005, 3:e159.
5. Hirano M., Kato S., Kobayashi K., Okada T., Yaginuma H., Kobayashi K. Highly efficient retrograde gene transfer into motor neurons by a lentiviral vector pseudotyped with fusion glycoprotein. PLoS ONE 2013, 8:e75896.
6. Kato S., Kuramochi M., Kobayashi K., Fukabori R., Okada K., Uchigashima M., Watanabe M., Tsutsui Y., Kobayashi K. Selective neural pathway targeting reveals key roles of thalamostriatal projection in the control of visual discrimination. J. Neurosci. 2011, 31:17169-17179.
7. Kato S., Kuramochi M., Takasumi K., Kobayashi K., Inoue K., Takahara D., Hitoshi S., Ikenaka K., Shimada T., Takada M., Kobayashi K. Neuron-specific gene transfer through retrograde transport of lentiviral vector pseudotyped with a novel type of fusion envelope glycoprotein. Hum. Gene Ther. 2011, 22:1511-1523.
8. Marshel J.H., Mori T., Nielsen K.J., Callaway E.M. Targeting single neuronal networks for gene expression and cell labeling in vivo. Neuron 2010, 67:562-574.
9. Miyamichi K., Shlomai-Fuchs Y., Shu M., Weissbourd B.C., Luo L., Mizrahi A. Dissecting local circuits: parvalbumin interneurons underlie broad feedback control of olfactory bulb output. Neuron 2013, 80:1232-1245.
10. Mori T., Morimoto K. Rabies virus glycoprotein variants display different patterns in rabies monosynaptic tracing. Front. Neuroanat. 2014, 7:47.
11. Nathanson J.L., Yanagawa Y., Obata K., Callaway E.M. Preferential labeling of inhibitory and excitatory cortical neurons by endogenous tropism of adeno-associated virus and lentivirus vectors. Neuroscience 2009, 161:441-450.
12. Osakada F., Callaway E.M. Design and generation of recombinant rabies virus vectors. Nat. Protoc. 2013, 8:1583-1601.
13. Osakada F., Mori T., Cetin A.H., Marshel J.H., Virgen B., Callaway E.M. New rabies virus variants for monitoring and manipulating activity and gene expression in defined neural circuits. Neuron 2011, 71:617-631.
14. Paxinos G., Franklin K.B.J., Franklin K.B.J. The Mouse Brain in Stereotaxic Coordinates 2001, Academic Press. Second Edition.
15. Reardon T.R., Murray A.J., Turi G.F., Wirblich C., Croce K.R., Schnell M.J., Jessell T.M., Losonczy A. Rabies Virus CVS-N2c(δG) Strain Enhances Retrograde Synaptic Transfer and Neuronal Viability. Neuron 2016, 89:711-724.
16. Schnell M.J., McGettigan J.P., Wirblich C., Papaneri A. The cell biology of rabies virus: using stealth to reach the brain. Nat. Rev. Microbiol. 2010, 8:51-61.
17. Seidler B., Schmidt A., Mayr U., Nakhai H., Schmid R.M., Schneider G., Saur D. A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors. Proc. Natl. Acad. Sci. USA 2008, 105:10137-10142.
18. Sena-Esteves M., Tebbets J.C., Steffens S., Crombleholme T., Flake A.W. Optimized large-scale production of high titer lentivirus vector pseudotypes. J. Virol. Methods 2004, 122:131-139.
19. Sievers F., Wilm A., Dineen D., Gibson T.J., Karplus K., Li W., Lopez R., McWilliam H., Remmert M., Söding J., et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol. Syst. Biol. 2011, 7:539.
20. Ugolini G. Use of rabies virus as a transneuronal tracer of neuronal connections: implications for the understanding of rabies pathogenesis. Dev. Biol. (Basel) 2008, 131:493-506.
21. Wall N.R., Wickersham I.R., Cetin A., De La Parra M., Callaway E.M. Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus. Proc. Natl. Acad. Sci. USA 2010, 107:21848-21853.
22. Watabe-Uchida M., Zhu L., Ogawa S.K., Vamanrao A., Uchida N. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron 2012, 74:858-873.
23. Wertz A., Trenholm S., Yonehara K., Hillier D., Raics Z., Leinweber M., Szalay G., Ghanem A., Keller G., Rózsa B., et al. PRESYNAPTIC NETWORKS. Single-cell-initiated monosynaptic tracing reveals layer-specific cortical network modules. Science 2015, 349:70-74.
24. Wickersham I.R., Finke S., Conzelmann K.K., Callaway E.M. Retrograde neuronal tracing with a deletion-mutant rabies virus. Nat. Methods 2007, 4:47-49.
25. Wickersham I.R., Lyon D.C., Barnard R.J.O., Mori T., Finke S., Conzelmann K.-K., Young J.A.T., Callaway E.M. Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 2007, 53:639-647.
26. Wirblich C., Schnell M.J. Rabies virus (RV) glycoprotein expression levels are not critical for pathogenicity of RV. J. Virol. 2011, 85:697-704.