Orthostatic myoclonus associated with Caspr2 antibodies

Neurology

Volumn 86, Issue 14, 2016, Pages 1353-1355

  Gövert, Felix ^a   Witt, Karsten ^a   Erro, Roberto ^b   Hellriegel, Helge ^a   Paschen, Steffen ^a   Martinez Hernandez, Eugenia ^c   Wandinger, Klaus Peter ^d   Deuschl, Günther ^a   Dalmau, Josep ^c,e,f   Leypoldt, Frank ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF LÜBECK   (Germany)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CARBAMAZEPINE; CONTACTIN ASSOCIATED PROTEIN 2; IMMUNOGLOBULIN; METHYLPREDNISOLONE; PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL COMPLEX ANTIBODY; AUTOANTIBODY; CNTNAP2 PROTEIN, HUMAN; IMMUNOLOGIC FACTOR; MEMBRANE PROTEIN; NERVE PROTEIN;

ADD ON THERAPY; AGED; ANTIBODY DETECTION; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; COGNITIVE DEFECT; DISEASE DURATION; DISEASE EXACERBATION; DISEASE SEVERITY; ELECTROMYOGRAM; FOLLOW UP; HERPES ZOSTER; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; MALE; MEMORY DISORDER; MYOCLONUS; NEUROPATHIC PAIN; NOTE; ORTHOSTATIC HYPOTENSION; ORTHOSTATIC MYOCLONUS; PLEOCYTOSIS; PRIORITY JOURNAL; PSYCHOSIS; RADIOIMMUNOASSAY; RECURRENT DISEASE; TREATMENT DURATION; UNSTEADINESS; BLOOD; BODY POSTURE; IMMUNOLOGY;

AGED; AUTOANTIBODIES; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; MALE; MEMBRANE PROTEINS; MYOCLONUS; NERVE TISSUE PROTEINS; POSTURE;

EID: 84963512927     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002547     Document Type: Note

References (7)

1. Glass GA, Ahlskog JE, Matsumoto JY. Orthostatic myoclonus: a contributor to gait decline in selected elderly. Neurology 2007;68:1826-1830.
2. Gasca-Salas C, Arcocha J, Artieda J, Pastor P. Orthostatic myoclonus: an underrecognized cause of unsteadiness? Parkinsonism Relat Disord 2013;19:1013-1017.
3. Lancaster E, Huijbers MG, Bar V, et al. Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia. Ann Neurol 2011;69:303-311.
4. Irani SR, Alexander S, Waters P, et al. Antibodies to Kv1 potassium channel-complex proteins leucinerich, glioma inactivated 1 protein and contactinassociated protein-2 in limbic encephalitis, Morvans syndrome and acquired neuromyotonia. Brain 2010; 133:2734-2748.
5. Klein CJ, Lennon VA, Aston PA, McKeon A, Pittock SJ. Chronic pain as a manifestation of potassium channelcomplex autoimmunity. Neurology 2012;79:1136-1144.
6. Hegde M, Glass GA, Dalmau J, Christine CW. A case of slow orthostatic tremor, responsive to intravenous immunoglobulin. Mov Disord 2011;26:1563-1565.
7. McKeon A, Pittock SJ, Glass GA, et al. Whole-body tremulousness: isolated generalized polymyoclonus. Arch Neurol 2007;64:1318-1322.