-
1
-
-
0034762203
-
The Raf/MEK/ERK pathway: new concepts of activation
-
C.Peyssonnaux, A.Eychene The Raf/MEK/ERK pathway:new concepts of activation. Biol Cell. 2001;93:53–62.
-
(2001)
Biol Cell
, vol.93
, pp. 53-62
-
-
Peyssonnaux, C.1
Eychene, A.2
-
2
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
H.Davies, G.R.Bignell, C.Cox,. Mutations of the BRAF gene in human cancer. Nature. 2002;417:949–54.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
3
-
-
65649090993
-
BRAF signaling and targeted therapies in melanoma
-
N.Dhomen, R.Marais BRAF signaling and targeted therapies in melanoma. Hematol Oncol Clin North Am. 2009;23:529–45.
-
(2009)
Hematol Oncol Clin North Am
, vol.23
, pp. 529-545
-
-
Dhomen, N.1
Marais, R.2
-
4
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
P.B.Chapman, A.Hauschild, C.Robert,. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507–16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
5
-
-
84864285704
-
. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
-
A.Hauschild, J.J.Grob, L.V.Demidov, et al. Dabrafenib in BRAF-mutated metastatic melanoma:a multicentre, open-label, phase 3 randomised controlled trial. Lancet. 2012;380:358–65.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
6
-
-
84944350959
-
Cutaneous toxic effects of BRAF inhibitors alone and in combination with MEK inhibitors for metastatic melanoma
-
G.Carlos, R.Anforth, A.Clements,. Cutaneous toxic effects of BRAF inhibitors alone and in combination with MEK inhibitors for metastatic melanoma. JAMA Dermatol. 2015;151:1103–9.
-
(2015)
JAMA Dermatol
, vol.151
, pp. 1103-1109
-
-
Carlos, G.1
Anforth, R.2
Clements, A.3
-
7
-
-
84937214638
-
. Dupuytren's contractures associated with the BRAF inhibitor vemurafenib: a case report
-
W.Chan, D.A.Vorobiof. Dupuytren's contractures associated with the BRAF inhibitor vemurafenib:a case report. J Med Case Rep. 2015;9:158.
-
(2015)
J Med Case Rep
, vol.9
, pp. 158
-
-
Chan, W.1
Vorobiof, D.A.2
-
8
-
-
84904099368
-
. Abrupt development of Dupuytren's contractures with the BRAF inhibitor vemurafenib
-
V.Sibaud, C.Chevreau. Abrupt development of Dupuytren's contractures with the BRAF inhibitor vemurafenib. Joint Bone Spine. 2014;81:373–4.
-
(2014)
Joint Bone Spine
, vol.81
, pp. 373-374
-
-
Sibaud, V.1
Chevreau, C.2
-
9
-
-
84913596734
-
The prevalence of Dupuytren contractures in patients with psoriasis
-
M.Patel, N.R.Freeman, S.Dhaliwal,. The prevalence of Dupuytren contractures in patients with psoriasis. Clin Exp Dermatol. 2014;39:894–9.
-
(2014)
Clin Exp Dermatol
, vol.39
, pp. 894-899
-
-
Patel, M.1
Freeman, N.R.2
Dhaliwal, S.3
-
10
-
-
84900807640
-
The role of tumor necrosis factor in the pathogenesis of immune-mediated diseases
-
C.Blandizzi, A.Gionchetti, A.Armuzzi,. The role of tumor necrosis factor in the pathogenesis of immune-mediated diseases. Int J Immunopathol Pharmacol. 2014;27:1–10.
-
(2014)
Int J Immunopathol Pharmacol
, vol.27
, pp. 1-10
-
-
Blandizzi, C.1
Gionchetti, A.2
Armuzzi, A.3
-
11
-
-
84874635531
-
. Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target
-
L.S.Verjee, J.S.Verhoekx, J.K.Chan, et al. Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target. Proc Natl Acad Sci USA. 2013;110:E928–37.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E928-E937
-
-
Verjee, L.S.1
Verhoekx, J.S.2
Chan, J.K.3
-
12
-
-
84896529503
-
Dynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatment
-
J.S.Wilmott, L.E.Haydu, A.M.Menzies,. Dynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatment. J Immunol. 2014;192:2505–13.
-
(2014)
J Immunol
, vol.192
, pp. 2505-2513
-
-
Wilmott, J.S.1
Haydu, L.E.2
Menzies, A.M.3
-
13
-
-
77949732073
-
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
-
P.I.Poulikakos, C.Zhang, G.Bollag,. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. Nature. 2010;464:427–30.
-
(2010)
Nature
, vol.464
, pp. 427-430
-
-
Poulikakos, P.I.1
Zhang, C.2
Bollag, G.3
-
14
-
-
84885346869
-
The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis
-
A.Mavropoulos, E.I.Rigopoulou, C.Liaskos,. The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis. Clin Dev Immunol. 2013;2013:569751.
-
(2013)
Clin Dev Immunol
, vol.2013
, pp. 569751
-
-
Mavropoulos, A.1
Rigopoulou, E.I.2
Liaskos, C.3
-
15
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
-
P.P.Roux, J.Blenis ERK and p38 MAPK-activated protein kinases:a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev. 2004;68:320–44.
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
|