The 2015 WHO Classification of tumors of the heart and pericardium

Journal of Thoracic Oncology

Volumn 11, Issue 4, 2016, Pages 441-452

  Burke, Allen ^a   Tavora, Fabio ^b  

^a UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^b Messejana Heart and Lung Hospital   (Brazil)

Author keywords

Classification; Germ cell tumor; Heart tumor; Myxoma; Pericardium; Sarcoma

Indexed keywords

ANGIOSARCOMA; BENIGN TUMOR; CARDIAC FIBROMA; CARDIAC LIPOMA; CARDIAC LYMPHOMA; CARDIAC PARAGANGLIOMA; CHILDHOOD CANCER; CLINICAL FEATURE; CONGENITAL TUMOR; FIBROELASTOMA; GENE; GERM CELL TUMOR; HAMARTOMA; HEART; HEART ATRIOVENTRICULAR NODE CYSTIC TUMOR; HEART ATRIUM SARCOMA; HEART ATRIUM SEPTUM LIPOMATOUS HYPERTROPHY; HEART MYXOMA; HEART SARCOMA; HEART TUMOR; HEMANGIOMA; HISTIOCYTOID CARDIOMYOPATHY; HUMAN; MALIGNANT FIBROUS HISTIOCYTOMA; MALIGNANT MESOTHELIOMA; NEOPLASMS OF UNCERTAIN BEHAVIOR; PAPILLARY FIBROELASTOMA; PATHOGENESIS; PERICARDIUM; PERICARDIUM SARCOMA; PERICARDIUM TUMOR; PLASMA CELL GRANULOMA; PRIORITY JOURNAL; PRKAR1A GENE; REVIEW; RHABDOMYOMA; RHABDOMYOSARCOMA; SOLITARY FIBROUS TUMOR; SOMATIC MUTATION; TERATOMA; TUMOR CLASSIFICATION; WORLD HEALTH ORGANIZATION; YOLK SAC TUMOR; CLASSIFICATION; PATHOLOGY;

HEART NEOPLASMS; HUMANS; PERICARDIUM; WORLD HEALTH ORGANIZATION;

EID: 84962873389     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1016/j.jtho.2015.11.009     Document Type: Review

References (29)

1. Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG, eds. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. 4th ed. Lyon, France: International Agency for Research on Cancer; 2015.
2. Miettinen M. Fibroblastic and myofibroblastic neoplasms with malignant potential. In: Miettinen M, ed. Modern Soft Tissue Pathology. Cambridge, United Kingdom: Cambridge University Press; 2010:348-392.
3. Weiss SW, Goldblum JR, Folpe AL, Undifferentiated pleomorphic sarcoma. Enzinger and Weiss's Soft Tissue Tumors. Philadelphia: Elseiver; 2014:421-442.
4. Fletcher CDM, Chibon F, Mertens F. Undifferentiated/unclassified sarcomas. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classification of Tumours of Soft Tissue and Bone. Lyon, France: International Agency for Research on Cancer; 2013:236 238.
5. Neuville A, Collin F, Bruneval P, et al. Intimal sarcoma is the most frequent primary cardiac sarcoma: clinicopathologic and molecular retrospective analysis of 100 primary cardiac sarcomas. Am J Surg Pathol. 2014;38:461-469.
6. Burke AP, Yi ES. Pulmonary artery intimal sarcoma. In: Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG, eds. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. 4th ed. Lyon, France: International Agency for Research on Cancer; 2015:128 129.
7. Bode-Lesniewska B, Debiec-Rychter M. Intimal sarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classification of Tumours of Soft Tissue and Bone. Lyon, France: International Agency for Research on Cancer; 2013:232 233.
8. Maleszewski JJ, Tavora F, Burke AP. Do "intimal" sarcomas of the heart exist? Am J Surg Pathol. 2014;38:1158-1159.
9. Burke AP, Tazelaar H, Butany JW, et al. Cardiac sarcomas. In: Travis W, Brambilla E, Muller-Hermelink HK, Harris CC, eds. Pathology & Genetics Tumours of the Lung, Pleura, Thymus and Heart. Lyon, France: International Agency for Research on Cancer; 2004:273-281.
10. Rosenberg AE. Extraskeletal osteosarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classification of Tumors of Soft Tissue and Bone. Lyon, France: International Agency for Research on Cancer; 2013:161-162.
11. Malhotra V, Ferrans VJ, Virmani R. Infantile histiocytoid cardiomyopathy: three cases and literature review. Am Heart J. 1994;128:1009-1021.
12. Shehata BM, Cundiff CA, Lee K, et al. Exome sequencing of patients with histiocytoid cardiomyopathy reveals a de novo NDUFB11 mutation that plays a role in the pathogenesis of histiocytoid cardiomyopathy. Am J Med Genet A. 2015;167A:2114-2121.
13. Vallance HD, Jeven G, Wallace DC, et al. A case of sporadic infantile histiocytoid cardiomyopathy caused by the A8344G (MERRF) mitochondrial DNA mutation. Pediatr Cardiol. 2004;25:538-540.
14. Raffa GM, Malvindi PG, Settepani F, et al. Hamartoma of mature cardiac myocytes in adults and young: case report and literature review. Int J Cardiol. 2013;163: e28-e30.
15. Burke AP, Ribe JK, Bajaj AK, et al. Hamartoma of mature cardiac myocytes. Hum Pathol. 1998;29:904-909.
16. Bhat SP, SI GG, Chikkatur R, et al. Lipomatous hamar-toma of mitral valve. Asian Cardiovasc Thorac Ann. 2016;35:34-35.
17. Bradshaw SH, Hendry P, Boodhwani M, et al. Left ventricular mesenchymal hamartoma, a new hamartoma of the heart. Cardiovasc Pathol. 2011;20:307-314.
18. Nathan M, Fabozzo A, Geva T, et al. Successful surgical management of ventricular fibromas in children. J Thorac Cardiovasc Surg. 2014;148:2602-2608.
19. Kobayashi D, L'Ecuyer TJ, Aggarwal S. Orthotopic heart transplant: a therapeutic option for unresectable cardiac fibroma in infants. Congenit Heart Dis. 2012;7:E31-E36.
20. Patel A, Rigsby C, Young L. Cardiac teratoma of the interventricular septum with congenital aortic stenosis in a newborn. Pediatr Cardiol. 2008;29:1126-1128.
21. Burke A, Jeudy J Jr, Virmani R. Cardiac tumours: an update: Cardiac tumours. Heart. 2008;94:117-123.
22. Burke A. Primary malignant cardiac tumors. Semin Diagn Pathol. 2008;25:39-46.
23. Bois MC, Bois JP, Anavekar NS, et al. Benign lipomatous masses of the heart: a comprehensive series of 47 cases with cytogenetic evaluation. Hum Pathol. 2014;45: 1859-1865.
24. MacGowan SW, Sidhu P, Aherne T, et al. Atrial myxoma: national incidence, diagnosis and surgical management. Ir J Med Sci. 1993;162:223-226.
25. Huo JL, Choi JC, DeLuna A, et al. Cardiac paraganglioma: diagnostic and surgical challenges. J Card Surg. 2012;27:178-182.
26. Jeudy J, Kirsch J, Tavora F, et al. From the radiologic pathology archives: cardiac lymphoma: radiologic-pathologic correlation. Radiographics. 2012;32:1369-1380.
27. Burke A, Johns JP, Virmani R. Hemangiomas of the heart. A clinicopathologic study of ten cases. Am J Cardiovasc Pathol. 1990;3:283-290.
28. Thomason R, Schlegel W, Lucca M, et al. Primary malignant mesothelioma of the pericardium. Case report and literature review. Tex Heart Inst J. 1994;21:170-174.
29. Burke A, Virmani R. Pediatric heart tumors. Cardiovasc Pathol. 2008;17:193-198.