-
4
-
-
84920655625
-
PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
-
D'Incecco A, Andreozzi M, Ludovini V, Rossi E, Capodanno A, Landi L, Tibaldi C, Minuti G, Salvini J, Coppi E, Chella A, Fontanini G, Filice ME, Tornillo L, Incensati RM, Sani S, et al. PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients. British journal of cancer. 2015; 112:95-102.
-
(2015)
British journal of cancer
, vol.112
, pp. 95-102
-
-
D'Incecco, A.1
Andreozzi, M.2
Ludovini, V.3
Rossi, E.4
Capodanno, A.5
Landi, L.6
Tibaldi, C.7
Minuti, G.8
Salvini, J.9
Coppi, E.10
Chella, A.11
Fontanini, G.12
Filice, M.E.13
Tornillo, L.14
Incensati, R.M.15
Sani, S.16
-
5
-
-
85052489122
-
Assessment of tumoral PD-L1 expression and intratumoral CD8+ T cells in urothelial carcinoma
-
e701-706
-
Faraj SF, Munari E, Guner G, Taube J, Anders R, Hicks J, Meeker A, Schoenberg M, Bivalacqua T, Drake C and Netto GJ. Assessment of tumoral PD-L1 expression and intratumoral CD8+ T cells in urothelial carcinoma. Urology. 2015; 85:703.e701-706.
-
(2015)
, vol.85
, pp. 703
-
-
Faraj, S.F.1
Munari, E.2
Guner, G.3
Taube, J.4
Anders, R.5
Hicks, J.6
Meeker, A.7
Schoenberg, M.8
Bivalacqua, T.9
Drake, C.10
Netto, G.J.11
-
6
-
-
85006224689
-
Programmed cell death protein 1 and programmed death-ligand 1 are expressed on the surface of some small-cell lung cancer lines
-
Yamane H, Isozaki H, Takeyama M, Ochi N, Kudo K, Honda Y, Yamagishi T, Kubo T, Kiura K and Takigawa N. Programmed cell death protein 1 and programmed death-ligand 1 are expressed on the surface of some small-cell lung cancer lines. American journal of cancer research. 2015; 5:1553-1557.
-
(2015)
American journal of cancer research
, vol.5
, pp. 1553-1557
-
-
Yamane, H.1
Isozaki, H.2
Takeyama, M.3
Ochi, N.4
Kudo, K.5
Honda, Y.6
Yamagishi, T.7
Kubo, T.8
Kiura, K.9
Takigawa, N.10
-
7
-
-
84945475723
-
Frequent expression of PD-L1 on circulating breast cancer cells
-
Mazel M, Jacot W, Pantel K, Bartkowiak K, Topart D, Cayrefourcq L, Rossille D, Maudelonde T, Fest T and Alix-Panabieres C. Frequent expression of PD-L1 on circulating breast cancer cells. Mol Oncol. 2015; 9:1773-1782.
-
(2015)
Mol Oncol
, vol.9
, pp. 1773-1782
-
-
Mazel, M.1
Jacot, W.2
Pantel, K.3
Bartkowiak, K.4
Topart, D.5
Cayrefourcq, L.6
Rossille, D.7
Maudelonde, T.8
Fest, T.9
Alix-Panabieres, C.10
-
8
-
-
84929515280
-
PD-L1 is highly expressed in lung lymphoepithelioma-like carcinoma: A potential rationale for immunotherapy
-
Chang YL, Yang CY, Lin MW, Wu CT and Yang PC. PD-L1 is highly expressed in lung lymphoepithelioma-like carcinoma: A potential rationale for immunotherapy. Lung cancer. 2015; 88:254-259.
-
(2015)
Lung cancer
, vol.88
, pp. 254-259
-
-
Chang, Y.L.1
Yang, C.Y.2
Lin, M.W.3
Wu, C.T.4
Yang, P.C.5
-
12
-
-
84926079153
-
Anti-PD-L1 antibody active in metastatic bladder cancer
-
Brower V. Anti-PD-L1 antibody active in metastatic bladder cancer. The Lancet Oncology. 2015; 16:e11.
-
(2015)
The Lancet Oncology
, vol.16
-
-
Brower, V.1
-
13
-
-
84905975277
-
B7-H1/PD-1 blockade therapy in non-small cell lung cancer: current status and future direction
-
Gettinger S and Herbst RS. B7-H1/PD-1 blockade therapy in non-small cell lung cancer: current status and future direction. Cancer journal. 2014; 20:281-289.
-
(2014)
Cancer journal
, vol.20
, pp. 281-289
-
-
Gettinger, S.1
Herbst, R.S.2
-
14
-
-
84921779027
-
PD-1 blockade therapy in renal cell carcinoma: Current studies and future promises
-
Massari F, Santoni M, Ciccarese C, Santini D, Alfieri S, Martignoni G, Brunelli M, Piva F, Berardi R, Montironi R, Porta C, Cascinu S and Tortora G. PD-1 blockade therapy in renal cell carcinoma: Current studies and future promises. Cancer treatment reviews. 2015; 41:114-121.
-
(2015)
Cancer treatment reviews
, vol.41
, pp. 114-121
-
-
Massari, F.1
Santoni, M.2
Ciccarese, C.3
Santini, D.4
Alfieri, S.5
Martignoni, G.6
Brunelli, M.7
Piva, F.8
Berardi, R.9
Montironi, R.10
Porta, C.11
Cascinu, S.12
Tortora, G.13
-
15
-
-
84925529257
-
Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
-
Ohaegbulam KC, Assal A, Lazar-Molnar E, Yao Y and Zang X. Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. Trends in molecular medicine. 2015; 21:24-33.
-
(2015)
Trends in molecular medicine
, vol.21
, pp. 24-33
-
-
Ohaegbulam, K.C.1
Assal, A.2
Lazar-Molnar, E.3
Yao, Y.4
Zang, X.5
-
16
-
-
84923186335
-
Immunotherapy: PD-1-PD-L1 axis: efficient checkpoint blockade against cancer
-
Errico A. Immunotherapy: PD-1-PD-L1 axis: efficient checkpoint blockade against cancer. Nature reviews Clinical oncology. 2015; 12:63.
-
(2015)
Nature reviews Clinical oncology
, vol.12
, pp. 63
-
-
Errico, A.1
-
17
-
-
84935474357
-
PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy
-
Patel SP and Kurzrock R. PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy. Mol Cancer Ther. 2015; 14:847-856.
-
(2015)
Mol Cancer Ther
, vol.14
, pp. 847-856
-
-
Patel, S.P.1
Kurzrock, R.2
-
18
-
-
84939227614
-
Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers
-
Carbognin L, Pilotto S, Milella M, Vaccaro V, Brunelli M, Calio A, Cuppone F, Sperduti I, Giannarelli D, Chilosi M, Bronte V, Scarpa A, Bria E and Tortora G. Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers. PloS one. 2015; 10:e0130142.
-
(2015)
PloS one
, vol.10
-
-
Carbognin, L.1
Pilotto, S.2
Milella, M.3
Vaccaro, V.4
Brunelli, M.5
Calio, A.6
Cuppone, F.7
Sperduti, I.8
Giannarelli, D.9
Chilosi, M.10
Bronte, V.11
Scarpa, A.12
Bria, E.13
Tortora, G.14
-
20
-
-
84926528302
-
Overcoming T cell exhaustion in infection and cancer
-
Pauken KE and Wherry EJ. Overcoming T cell exhaustion in infection and cancer. Trends in immunology. 2015; 36:265-276.
-
(2015)
Trends in immunology
, vol.36
, pp. 265-276
-
-
Pauken, K.E.1
Wherry, E.J.2
-
21
-
-
84905982850
-
Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation
-
Sanmamed MF and Chen L. Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation. Cancer journal. 2014; 20:256-261.
-
(2014)
Cancer journal
, vol.20
, pp. 256-261
-
-
Sanmamed, M.F.1
Chen, L.2
-
22
-
-
84923090821
-
Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma
-
Ritprajak P and Azuma M. Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma. Oral oncology. 2015; 51:221-228.
-
(2015)
Oral oncology
, vol.51
, pp. 221-228
-
-
Ritprajak, P.1
Azuma, M.2
-
23
-
-
64849103123
-
Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches
-
Wasik MA, Zhang Q, Marzec M, Kasprzycka M, Wang HY and Liu X. Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches. Seminars in oncology. 2009; 36:S27-35.
-
(2009)
Seminars in oncology
, vol.36
, pp. S27-35
-
-
Wasik, M.A.1
Zhang, Q.2
Marzec, M.3
Kasprzycka, M.4
Wang, H.Y.5
Liu, X.6
-
24
-
-
84893951437
-
PTEN/PI3K/mTOR/B7-H1 signaling pathway regulates cell progression and immuno-resistance in pancreatic cancer
-
Zhang Y, Zhang J, Xu K, Xiao Z, Sun J, Xu J, Wang J and Tang Q. PTEN/PI3K/mTOR/B7-H1 signaling pathway regulates cell progression and immuno-resistance in pancreatic cancer. Hepato-gastroenterology. 2013; 60:1766-1772.
-
(2013)
Hepato-gastroenterology
, vol.60
, pp. 1766-1772
-
-
Zhang, Y.1
Zhang, J.2
Xu, K.3
Xiao, Z.4
Sun, J.5
Xu, J.6
Wang, J.7
Tang, Q.8
-
25
-
-
84924569931
-
Molecular drivers of cellular metabolic reprogramming in melanoma
-
Abildgaard C and Guldberg P. Molecular drivers of cellular metabolic reprogramming in melanoma. Trends in molecular medicine. 2015; 21:164-171.
-
(2015)
Trends in molecular medicine
, vol.21
, pp. 164-171
-
-
Abildgaard, C.1
Guldberg, P.2
-
26
-
-
84920887662
-
Biomarkers for personalized oncology: recent advances and future challenges
-
Kalia M. Biomarkers for personalized oncology: recent advances and future challenges. Metabolism: clinical and experimental. 2015; 64:S16-21.
-
(2015)
Metabolism: clinical and experimental
, vol.64
, pp. S16-21
-
-
Kalia, M.1
-
27
-
-
84923599043
-
PTEN: Multiple Functions in Human Malignant Tumors
-
Milella M, Falcone I, Conciatori F, Cesta Incani U, Del Curatolo A, Inzerilli N, Nuzzo CM, Vaccaro V, Vari S, Cognetti F and Ciuffreda L. PTEN: Multiple Functions in Human Malignant Tumors. Frontiers in oncology. 2015; 5:24.
-
(2015)
Frontiers in oncology
, vol.5
, pp. 24
-
-
Milella, M.1
Falcone, I.2
Conciatori, F.3
Cesta Incani, U.4
Del Curatolo, A.5
Inzerilli, N.6
Nuzzo, C.M.7
Vaccaro, V.8
Vari, S.9
Cognetti, F.10
Ciuffreda, L.11
-
28
-
-
84943143291
-
Current Status and Future Directions of the Immune Checkpoint Inhibitors Ipilimumab, Pembrolizumab, and Nivolumab in Oncology
-
Barbee MS, Ogunniyi A, Horvat TZ and Dang TO. Current Status and Future Directions of the Immune Checkpoint Inhibitors Ipilimumab, Pembrolizumab, and Nivolumab in Oncology. The Annals of pharmacotherapy. 2015.
-
(2015)
The Annals of pharmacotherapy
-
-
Barbee, M.S.1
Ogunniyi, A.2
Horvat, T.Z.3
Dang, T.O.4
-
31
-
-
84960096478
-
Companion diagnostic assays for PD-1/PD-L1 checkpoint inhibitors in NSCLC
-
Jorgensen JT. Companion diagnostic assays for PD-1/PD-L1 checkpoint inhibitors in NSCLC. Expert review of molecular diagnostics. 2015:1-3.
-
(2015)
Expert review of molecular diagnostics
, pp. 1-3
-
-
Jorgensen, J.T.1
-
32
-
-
84918545182
-
Anti-programmed death receptor 1 immunotherapy in melanoma: rationale, evidence and clinical potential
-
Freeman-Keller M and Weber JS. Anti-programmed death receptor 1 immunotherapy in melanoma: rationale, evidence and clinical potential. Therapeutic advances in medical oncology. 2015; 7:12-21.
-
(2015)
Therapeutic advances in medical oncology
, vol.7
, pp. 12-21
-
-
Freeman-Keller, M.1
Weber, J.S.2
-
33
-
-
85015467210
-
Immune checkpoint inhibitors: therapeutic advances in melanoma
-
Marquez-Rodas I, Cerezuela P, Soria A, Berrocal A, Riso A, Gonzalez-Cao M and Martin-Algarra S. Immune checkpoint inhibitors: therapeutic advances in melanoma. Annals of translational medicine. 2015; 3:267.
-
(2015)
Annals of translational medicine
, vol.3
, pp. 267
-
-
Marquez-Rodas, I.1
Cerezuela, P.2
Soria, A.3
Berrocal, A.4
Riso, A.5
Gonzalez-Cao, M.6
Martin-Algarra, S.7
-
34
-
-
84928605037
-
Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis
-
Jia M, Feng W, Kang S, Zhang Y, Shen J, He J, Jiang L, Wang W, Guo Z, Peng G, Chen G, He J and Liang W. Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis. Journal of thoracic disease. 2015; 7:455-461.
-
(2015)
Journal of thoracic disease
, vol.7
, pp. 455-461
-
-
Jia, M.1
Feng, W.2
Kang, S.3
Zhang, Y.4
Shen, J.5
He, J.6
Jiang, L.7
Wang, W.8
Guo, Z.9
Peng, G.10
Chen, G.11
He, J.12
Liang, W.13
-
35
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014; 515:563-567.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
Sosman, J.A.7
McDermott, D.F.8
Powderly, J.D.9
Gettinger, S.N.10
Kohrt, H.E.11
Horn, L.12
Lawrence, D.P.13
Rost, S.14
Leabman, M.15
Xiao, Y.16
-
37
-
-
84962007127
-
Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation
-
Van Allen EM, Golay HG, Liu Y, Koyama S, Wong K, Taylor-Weiner A, Giannakis M, Harden M, Rojas-Rudilla V, Chevalier A, Thai T, Lydon C, Mach S, Avila AG, Wong JA, Rabin AR, et al. Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation. Cancer Immunol Res. 2015; 3:855-863.
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 855-863
-
-
Van Allen, E.M.1
Golay, H.G.2
Liu, Y.3
Koyama, S.4
Wong, K.5
Taylor-Weiner, A.6
Giannakis, M.7
Harden, M.8
Rojas-Rudilla, V.9
Chevalier, A.10
Thai, T.11
Lydon, C.12
Mach, S.13
Avila, A.G.14
Wong, J.A.15
Rabin, A.R.16
-
38
-
-
84938329177
-
PD-L1 and Survival in Solid Tumors: A Meta-Analysis
-
Wu P, Wu D, Li L, Chai Y and Huang J. PD-L1 and Survival in Solid Tumors: A Meta-Analysis. PloS one. 2015; 10:e0131403.
-
(2015)
PloS one
, vol.10
-
-
Wu, P.1
Wu, D.2
Li, L.3
Chai, Y.4
Huang, J.5
-
39
-
-
84962839973
-
Inhibitors of the PD-1/PD-L1 Pathway Can Mobilize the Immune System: An Innovative Potential Therapy for Cancer and Chronic Infections
-
Abdel-Magid AF. Inhibitors of the PD-1/PD-L1 Pathway Can Mobilize the Immune System: An Innovative Potential Therapy for Cancer and Chronic Infections. ACS medicinal chemistry letters. 2015; 6:489-490.
-
(2015)
ACS medicinal chemistry letters
, vol.6
, pp. 489-490
-
-
Abdel-Magid, A.F.1
-
40
-
-
84891528539
-
PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival
-
Lipson EJ, Vincent JG, Loyo M, Kagohara LT, Luber BS, Wang H, Xu H, Nayar SK, Wang TS, Sidransky D, Anders RA, Topalian SL and Taube JM. PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival. Cancer immunology research. 2013; 1:54-63.
-
(2013)
Cancer immunology research
, vol.1
, pp. 54-63
-
-
Lipson, E.J.1
Vincent, J.G.2
Loyo, M.3
Kagohara, L.T.4
Luber, B.S.5
Wang, H.6
Xu, H.7
Nayar, S.K.8
Wang, T.S.9
Sidransky, D.10
Anders, R.A.11
Topalian, S.L.12
Taube, J.M.13
-
41
-
-
80052365815
-
Upregulation of circulating PD-L1/PD-1 is associated with poor post-cryoablation prognosis in patients with HBV-related hepatocellular carcinoma
-
Zeng Z, Shi F, Zhou L, Zhang MN, Chen Y, Chang XJ, Lu YY, Bai WL, Qu JH, Wang CP, Wang H, Lou M, Wang FS, Lv JY and Yang YP. Upregulation of circulating PD-L1/PD-1 is associated with poor post-cryoablation prognosis in patients with HBV-related hepatocellular carcinoma. PloS one. 2011; 6:e23621.
-
(2011)
PloS one
, vol.6
-
-
Zeng, Z.1
Shi, F.2
Zhou, L.3
Zhang, M.N.4
Chen, Y.5
Chang, X.J.6
Lu, Y.Y.7
Bai, W.L.8
Qu, J.H.9
Wang, C.P.10
Wang, H.11
Lou, M.12
Wang, F.S.13
Lv, J.Y.14
Yang, Y.P.15
-
42
-
-
84875475811
-
Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
-
Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM and Pai SI. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer research. 2013; 73:1733-1741.
-
(2013)
Cancer research
, vol.73
, pp. 1733-1741
-
-
Lyford-Pike, S.1
Peng, S.2
Young, G.D.3
Taube, J.M.4
Westra, W.H.5
Akpeng, B.6
Bruno, T.C.7
Richmon, J.D.8
Wang, H.9
Bishop, J.A.10
Chen, L.11
Drake, C.G.12
Topalian, S.L.13
Pardoll, D.M.14
Pai, S.I.15
-
43
-
-
84920031403
-
EBV-driven LMP1 and IFN-gamma up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy
-
Fang W, Zhang J, Hong S, Zhan J, Chen N, Qin T, Tang Y, Zhang Y, Kang S, Zhou T, Wu X, Liang W, Hu Z, Ma Y, Zhao Y, Tian Y, et al. EBV-driven LMP1 and IFN-gamma up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy. Oncotarget. 2014; 5:12189-12202. doi: 10.18632/oncotarget.2608.
-
(2014)
Oncotarget
, vol.5
, pp. 12189-12202
-
-
Fang, W.1
Zhang, J.2
Hong, S.3
Zhan, J.4
Chen, N.5
Qin, T.6
Tang, Y.7
Zhang, Y.8
Kang, S.9
Zhou, T.10
Wu, X.11
Liang, W.12
Hu, Z.13
Ma, Y.14
Zhao, Y.15
Tian, Y.16
|