Rectal Indomethacin Does Not Prevent Post-ERCP Pancreatitis in Consecutive Patients

Gastroenterology

Volumn 150, Issue 4, 2016, Pages 911-917

  Levenick, John M ^a,b   Gordon, Stuart R ^a   Fadden, Linda L ^a   Campbell Levy, L ^a   Rockacy, Matthew J ^a   Hyder, Sarah M ^a   Lacy, Brian E ^a   Bensen, Steven P ^a   Parr, Douglas D ^a   Gardner, Timothy B ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

ESGE Recommendation; Inflammation; NSAID; Pancreas

Indexed keywords

INDOMETACIN; PLACEBO; TRIACYLGLYCEROL LIPASE; BIOLOGICAL MARKER; NONSTEROID ANTIINFLAMMATORY AGENT; PNLIP PROTEIN, HUMAN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; FOLLOW UP; HEALTH CARE FACILITY; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PANCREATIC DUCT STENT; PANCREATITIS; POST ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY PANCREATITIS; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TREATMENT OUTCOME; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; UPPER ABDOMINAL PAIN; ABDOMINAL PAIN; ADVERSE EFFECTS; EARLY TERMINATION OF CLINICAL TRIAL; MIDDLE AGED; NEW HAMPSHIRE; RECTAL DRUG ADMINISTRATION; RISK FACTOR; SEVERITY OF ILLNESS INDEX; TIME FACTOR; UPREGULATION;

ABDOMINAL PAIN; ADMINISTRATION, RECTAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOMARKERS; CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE; DOUBLE-BLIND METHOD; EARLY TERMINATION OF CLINICAL TRIALS; FEMALE; HUMANS; INDOMETHACIN; LIPASE; MALE; MEDICAL FUTILITY; MIDDLE AGED; NEW HAMPSHIRE; PANCREATITIS; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME; UP-REGULATION;

EID: 84962840857     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.12.040     Document Type: Article

References (25)

1. A.F. Peery, E.S. Dellon, J. Lund, and et al. Burden of gastrointestinal disease in the United States: 2012 update Gastroenterology 143 2012 1179 1187
2. M.L. Freeman, D.B. Nelson, S. Sherman, and et al. Complications of endoscopic biliary sphincterotomy N Engl J Med 335 1996 909 918
3. National Inpatient Sample-Healthcare Cost and Utilization Project. Rockville, MD: Agency for Healthcare Research and Quality. Available from: www.hcupnet.ahrq.gov. Accessed: April, 2015.
4. A. Fazel, A. Quadri, M.F. Catalano, and et al. Does a pancreatic duct stent prevent post-ERCP pancreatitis? A prospective randomized study Gastrointest Endosc 57 2003 291 294
5. P.R. Tarnasky, Y.Y. Palesch, J.T. Cunningham, and et al. Pancreatic stenting prevents pancreatitis after biliary sphincterotomy in patients with sphincter of Oddi dysfunction Gastroenterology 115 1998 1518 1524
6. R. Sotoudehmanesh, M. Khatibian, S. Kolahdoozan, and et al. Indomethacin may reduce the incidence and severity of acute pancreatitis after ERCP Am J Gastroenterol 102 2007 978 983
7. B. Murray, R. Carter, C. Imrie, and et al. Diclofenac reduces the incidence of acute pancreatitis after endoscopic retrograde cholangiopancreatography Gastroenterology 124 2003 1786 1791
8. B.J. Elmunzer, J.M. Scheiman, G.A. Lehman, and et al. A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis N Engl J Med 366 2012 1414 1422
9. J.M. Dumonceau, A. Andriulli, B.J. Elmunzer, and et al. Prophylaxis of post-ERCP pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - updated June 2014 Endoscopy 46 2014 799 815
10. Available from: www.consort-statement.org.
11. P.A. Banks, T.L. Bollen, C. Dervenis, and et al. Classification of acute pancreatitis-2012: revision of Atlanta classification and definitions by international consensus Gut 62 2013 102 111
12. W.D. Dupont Power calculations for matched case-control studies Biometrics 44 1988 1157 1168
13. J.J. Chen, X.M. Wang, X.Q. Liu, and et al. Risk factors for post-ERCP pancreatitis: a systematic review of clinical trials with a large sample size in the past 10 years Eur J Med Res 19 2014 26
14. H.F. Dai, X.W. Wang, and K. Zhao Role of nonsteroidal anti-inflammatory drugs in the prevention of post-ERCP pancreatitis: a meta-analysis Hepatobiliary Pancreat Dis Int 8 2009 11 16
15. B. Elmunzer, A. Waljee, G. Elta, and et al. A meta-analysis of rectal NSAIDS in the prevention of post-ERCP pancreatitis Gut 57 2008 1262
16. M.-H. Zheng, H. Xia, and Y.-P. Chen Rectal administration of NSAIDs in the prevention of post-ERCP Pancreatitis: a complementary meta-analysis Gut 57 2008 1632
17. X. Ding, M. Chen, S. Huang, and et al. Nonsteroidal anti-inflammatory drugs for prevention of post-ERCP pancreatitis: a meta-analysis Gastrointest Endosc 76 2012 1152 1159
18. M. Yahoobi, S. Rolland, K.A. Waschke, and et al. Meta-analysis: rectal indomethacin for the prevention of post-ERCP pancreatitis Aliment Pharmacol Ther 38 2013 995 1001
19. H.L. Sun, B. Han, H.P. Zhai, and et al. Rectal NSAIDs for the prevention of post-ERCP pancreatitis: a meta-analysis of randomized controlled trials Surgeon 12 2014 141 147
20. H. Yuhara, M. Ogawa, Y. Kawaguchi, and et al. Pharmacologic prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: protease inhibitors and NSAIDs in a meta-analysis J Gastroenterol 49 2014 388 399
21. S. Sethi, N. Sethi, V. Wadhwa, and et al. A meta-analysis on the role of rectal diclofenac and indomethacin in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis Pancreas 43 2014 190 197
22. ASGE Standard of Practice Committee Complications of ERCP Gastrointest Endosc 75 2012 476-473
23. B.J. Elmunzer, P.D. Higgins, S.D. Saini, and et al. Does rectal indomethacin eliminate the need for prophylactic stent placement in patients undergoing high-risk ERCP? Post hoc efficacy and cost-benefit analyses using prospective clinical trial data Am J Gastroenterol 108 2013 410 415
24. T.H. Baron, B.K. Abu Dayyeh, and A.R. Zinsmeister Rectal indomethacin to prevent post-ERCP pancreatitis N Engl J Med 367 2012 277 278
25. M.L. Freeman, J.A. DiSario, D.B. Nelson, and et al. Risk factors for post-ERCP pancreatitis: a prospective, multicenter study Gastrointest Endosc 54 2001 425 434