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Volumn 31, Issue 1, 2016, Pages 161-167

Effects of dipeptidyl peptidase-4 inhibitors on hyperglycemia and blood cyclosporine levels in renal transplant patients with diabetes: A pilot study

Author keywords

Cyclosporine; Diabetes mellitus; Dipeptidyl peptidase IV inhibitors; Kidney transplantation; Linagliptin; Sitagliptin phosphate; Vildagliptin

Indexed keywords


EID: 84962705569     PISSN: 2093596X     EISSN: 20935978     Source Type: Journal    
DOI: 10.3803/EnM.2016.31.1.161     Document Type: Article
Times cited : (27)

References (28)
  • 2
    • 15044357134 scopus 로고    scopus 로고
    • Long-term prognosis of patients after kidney transplantation: a comparison of those with or without diabetes mellitus
    • Schiel R, Heinrich S, Steiner T, Ott U, Stein G. Long-term prognosis of patients after kidney transplantation: a comparison of those with or without diabetes mellitus. Nephrol Dial Transplant 2005;20:611-7.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 611-617
    • Schiel, R.1    Heinrich, S.2    Steiner, T.3    Ott, U.4    Stein, G.5
  • 3
    • 77951758117 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
    • Neumiller JJ, Wood L, Campbell RK. Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus. Pharmacotherapy 2010;30:463-84.
    • (2010) Pharmacotherapy , vol.30 , pp. 463-484
    • Neumiller, J.J.1    Wood, L.2    Campbell, R.K.3
  • 4
    • 74349122900 scopus 로고    scopus 로고
    • Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors
    • Davidson JA. Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors. Cleve Clin J Med 2009;76 Suppl 5:S28-38.
    • (2009) Cleve Clin J Med , vol.76 , pp. S28-S38
    • Davidson, J.A.1
  • 5
    • 79959773411 scopus 로고    scopus 로고
    • DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors
    • Dicker D. DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors. Diabetes Care 2011;34 Suppl 2:S276-8.
    • (2011) Diabetes Care , vol.34 , pp. S276-S288
    • Dicker, D.1
  • 6
    • 77955456705 scopus 로고    scopus 로고
    • Pharmacokinetics of dipeptidylpeptidase-4 inhibitors
    • Scheen AJ. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. Diabetes Obes Metab 2010;12:648-58.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 648-658
    • Scheen, A.J.1
  • 7
    • 84857917241 scopus 로고    scopus 로고
    • Excretion of the dipeptidyl peptidase-4 inhibitor linagliptin in rats is primarily by biliary excretion and P-gp-mediated efflux
    • Fuchs H, Runge F, Held HD. Excretion of the dipeptidyl peptidase-4 inhibitor linagliptin in rats is primarily by biliary excretion and P-gp-mediated efflux. Eur J Pharm Sci 2012;45:533-8.
    • (2012) Eur J Pharm Sci , vol.45 , pp. 533-538
    • Fuchs, H.1    Runge, F.2    Held, H.D.3
  • 9
    • 34548812349 scopus 로고    scopus 로고
    • Therapeutic monitoring of calcineurin inhibitors for the nephrologist
    • Schiff J, Cole E, Cantarovich M. Therapeutic monitoring of calcineurin inhibitors for the nephrologist. Clin J Am Soc Nephrol 2007;2:374-84.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 374-384
    • Schiff, J.1    Cole, E.2    Cantarovich, M.3
  • 10
    • 0032128129 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of cyclosporine and tacrolimus. Update on Lake Louise Consensus Conference on cyclosporin and tacrolimus
    • Oellerich M, Armstrong VW, Schutz E, Shaw LM. Therapeutic drug monitoring of cyclosporine and tacrolimus. Update on Lake Louise Consensus Conference on cyclosporin and tacrolimus. Clin Biochem 1998;31:309-16.
    • (1998) Clin Biochem , vol.31 , pp. 309-316
    • Oellerich, M.1    Armstrong, V.W.2    Schutz, E.3    Shaw, L.M.4
  • 11
    • 34250331903 scopus 로고    scopus 로고
    • Transporter-mediated drug interactions: clinical implications and in vitro assessment
    • Lin JH. Transporter-mediated drug interactions: clinical implications and in vitro assessment. Expert Opin Drug Metab Toxicol 2007;3:81-92.
    • (2007) Expert Opin Drug Metab Toxicol , vol.3 , pp. 81-92
    • Lin, J.H.1
  • 12
    • 0028863807 scopus 로고
    • Alternative cyclosporine metabolic pathways and toxicity
    • Christians U, Sewing KF. Alternative cyclosporine metabolic pathways and toxicity. Clin Biochem 1995;28:547-59.
    • (1995) Clin Biochem , vol.28 , pp. 547-559
    • Christians, U.1    Sewing, K.F.2
  • 13
    • 12644272784 scopus 로고    scopus 로고
    • Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine
    • Lown KS, Mayo RR, Leichtman AB, Hsiao HL, Turgeon DK, Schmiedlin-Ren P, et al. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine. Clin Pharmacol Ther 1997;62:248-60.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 248-260
    • Lown, K.S.1    Mayo, R.R.2    Leichtman, A.B.3    Hsiao, H.L.4    Turgeon, D.K.5    Schmiedlin-Ren, P.6
  • 14
    • 0033574249 scopus 로고    scopus 로고
    • A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group
    • Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-70.
    • (1999) Ann Intern Med , vol.130 , pp. 461-470
    • Levey, A.S.1    Bosch, J.P.2    Lewis, J.B.3    Greene, T.4    Rogers, N.5    Roth, D.6
  • 16
    • 0034791022 scopus 로고    scopus 로고
    • Glycaemic control and graft loss following renal transplantation
    • Thomas MC, Mathew TH, Russ GR. Glycaemic control and graft loss following renal transplantation. Nephrol Dial Transplant 2001;16:1978-82.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1978-1982
    • Thomas, M.C.1    Mathew, T.H.2    Russ, G.R.3
  • 17
    • 77949407776 scopus 로고    scopus 로고
    • Glucose control is associated with patient survival in diabetic patients after renal transplantation
    • Wiesbauer F, Heinze G, Regele H, Horl WH, Schernthaner GH, Schwarz C, et al. Glucose control is associated with patient survival in diabetic patients after renal transplantation. Transplantation 2010;89:612-9.
    • (2010) Transplantation , vol.89 , pp. 612-619
    • Wiesbauer, F.1    Heinze, G.2    Regele, H.3    Horl, W.H.4    Schernthaner, G.H.5    Schwarz, C.6
  • 19
    • 84871935582 scopus 로고    scopus 로고
    • Vildagliptin preserves the mass and function of pancreatic ß cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
    • Hamamoto S, Kanda Y, Shimoda M, Tatsumi F, Kohara K, Tawaramoto K, et al. Vildagliptin preserves the mass and function of pancreatic ß cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes. Diabetes Obes Metab 2013;15:153-63.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 153-163
    • Hamamoto, S.1    Kanda, Y.2    Shimoda, M.3    Tatsumi, F.4    Kohara, K.5    Tawaramoto, K.6
  • 20
    • 84866303239 scopus 로고    scopus 로고
    • The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves ß-cell mass in non-obese diabetic mice
    • Jelsing J, Vrang N, van Witteloostuijn SB, Mark M, Klein T. The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves ß-cell mass in non-obese diabetic mice. J Endocrinol 2012;214:381-7.
    • (2012) J Endocrinol , vol.214 , pp. 381-387
    • Jelsing, J.1    Vrang, N.2    van Witteloostuijn, S.B.3    Mark, M.4    Klein, T.5
  • 21
    • 84855849888 scopus 로고    scopus 로고
    • Safety of dipeptidyl peptidase 4 inhibitors for treatment of type 2 diabetes
    • Mikhail N. Safety of dipeptidyl peptidase 4 inhibitors for treatment of type 2 diabetes. Curr Drug Saf 2011;6:304-9.
    • (2011) Curr Drug Saf , vol.6 , pp. 304-309
    • Mikhail, N.1
  • 22
    • 34247236764 scopus 로고    scopus 로고
    • Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein
    • Chu XY, Bleasby K, Yabut J, Cai X, Chan GH, Hafey MJ, et al. Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein. J Pharmacol Exp Ther 2007;321:673-83.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 673-683
    • Chu, X.Y.1    Bleasby, K.2    Yabut, J.3    Cai, X.4    Chan, G.H.5    Hafey, M.J.6
  • 23
    • 77955453343 scopus 로고    scopus 로고
    • Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions
    • Scheen AJ. Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions. Clin Pharmacokinet 2010;49:573-88.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 573-588
    • Scheen, A.J.1
  • 24
    • 34447628472 scopus 로고    scopus 로고
    • Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers
    • He YL, Sabo R, Sunkara G, Bizot MN, Riviere GJ, Leon S, et al. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers. J Clin Pharmacol 2007;47:998-1004.
    • (2007) J Clin Pharmacol , vol.47 , pp. 998-1004
    • He, Y.L.1    Sabo, R.2    Sunkara, G.3    Bizot, M.N.4    Riviere, G.J.5    Leon, S.6
  • 25
    • 77950197593 scopus 로고    scopus 로고
    • The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans
    • Blech S, Ludwig-Schwellinger E, Grafe-Mody EU, Withopf B, Wagner K. The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans. Drug Metab Dispos 2010;38:667-78.
    • (2010) Drug Metab Dispos , vol.38 , pp. 667-678
    • Blech, S.1    Ludwig-Schwellinger, E.2    Grafe-Mody, E.U.3    Withopf, B.4    Wagner, K.5
  • 26
    • 0034951265 scopus 로고    scopus 로고
    • Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients
    • Koziolek MJ, Riess R, Geiger H, Thevenod F, Hauser IA. Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. Kidney Int 2001;60:156-66.
    • (2001) Kidney Int , vol.60 , pp. 156-166
    • Koziolek, M.J.1    Riess, R.2    Geiger, H.3    Thevenod, F.4    Hauser, I.A.5
  • 27
    • 33846463003 scopus 로고    scopus 로고
    • Effect of a single cyclosporine dose on the single-dose pharmacokinetics of sitagliptin (MK-0431), a dipeptidyl peptidase-4 inhibitor, in healthy male subjects
    • Krishna R, Bergman A, Larson P, Cote J, Lasseter K, Dilzer S, et al. Effect of a single cyclosporine dose on the single-dose pharmacokinetics of sitagliptin (MK-0431), a dipeptidyl peptidase-4 inhibitor, in healthy male subjects. J Clin Pharmacol 2007;47:165-74.
    • (2007) J Clin Pharmacol , vol.47 , pp. 165-174
    • Krishna, R.1    Bergman, A.2    Larson, P.3    Cote, J.4    Lasseter, K.5    Dilzer, S.6
  • 28
    • 33748433791 scopus 로고    scopus 로고
    • Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction
    • Anglicheau D, Pallet N, Rabant M, Marquet P, Cassinat B, Meria P, et al. Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction. Kidney Int 2006;70:1019-25.
    • (2006) Kidney Int , vol.70 , pp. 1019-1025
    • Anglicheau, D.1    Pallet, N.2    Rabant, M.3    Marquet, P.4    Cassinat, B.5    Meria, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.