Acetyl hexapeptide-3 in a cosmetic formulation acts on skin mechanical properties - Clinical study

Brazilian Journal of Pharmaceutical Sciences

Volumn 51, Issue 4, 2015, Pages 901-909

  Tadini, Kassandra Azevedo ^a   Mercurio, Daiane Garcia ^a   Campos, Patrícia Maria Berardo Gonçalves Maia ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acetyl hexapeptide 3 clinical efficacy; Acetyl hexapeptide 3 use in cosmetic formulations; Anti aging cosmetics; Biophysical techniques; Clinical efficacy; Cosmetics

Indexed keywords

ACETYL HEXAPEPTIDE 3; COSMETIC; HEXAPEPTIDE; UNCLASSIFIED DRUG;

ADULT; ANISOTROPY; ARTICLE; BIOPHYSICS; CLINICAL STUDY; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; FACE; FEMALE; FOREARM; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; SKIN; STRATUM CORNEUM; VISCOELASTICITY; WATER CONTENT;

EID: 84962637959     PISSN: 19848250     EISSN: 21759790     Source Type: Journal    
DOI: 10.1590/S1984-82502015000400016     Document Type: Article

References (25)

1. ANCONI, G.L.; CAMPOS, P.M.B.G.M. Stability and clinical efficacy of cosmetic formulations containing different peptides. In: IFSCC CONGRESS, 25., 2008. Barcelona: Luton: IFSCC, 2008.
2. BLANES-MIRA, C.; CLEMENTE, J.; JODAS, G.; GIL, A.; FERNÁNDEZ-BALLESTER, G.; PONSATI, B.; GUTIERREZ, L.; PÉREZ-PAYÁ, E.; FERRER-MONTIEL, A. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int. J. Cosmet. Sci., v.24, n.5, p.303-310, 2002.
3. BLINCHMAN, C.W.; SERUP, J. Assessment of skin moisture: measurement of electrical conductance, capacitance and transepidermal water loss. Acta Derm. Venereol., v.68, n.4, p.284-290, 1988.
4. DAL'BELO S.E.; GASPAR, L.R.; MAIA CAMPOS P.M.B.G. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res. Technol., v.12, n.4, p.241-246, 2006.
5. DOBREV, H,P. Use of Cutometer to assess epidermal hydration. Skin Res. Technol., v.6, p.239-244, 2000.
6. DOBREV, H.P. A study of human skin mechanical properties by means of Cutometer. Folia Medica (Plovdiv), v.44, n.3, p.5-10, 2002.
7. FLUHR, J.W.; GLOOR, M.; LAZZERINI, S. Comparative study of five instruments measuring stratum corneum hydration (Corneometer CM820 and CM825, Skicon200, Nova DPM9003, DermaLab). Part 1. In vitro. Skin Res. Technol., v.5, n.3, p.161-170, 1999.
8. FLUHR, J.W.; GLOOR, M.; LAZZERINI, S.; KLEESZ, P., GRIESHABER, R. AND BERARDESCA, E. Comparative study of five instruments measuring stratum corneum hydration (Corneometer CM820 and CM825, Skicon200, Nova DPM9003, DermaLab). Part 2. In vivo. Skin Res. Technol., v.5, n.3, p.171-178, 1999.
9. HAFTEK M, MAC-MARY S, LE BITOUX MA, CREIDI P, SEITÉ S, ROUGIER A, HUMBERT P. Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. Exp. Dermatol., v.7, n.11, p.946-952, 2008.
10. HERMANNS-LÊ, T.; JONLETA, F.; SCHEENB, A.; PIÉRARD G.E. Age-and body mass index-related changes in cutaneous shear wave velocity. Exp. Gerontol., v.36, n.2, p.363-372, 2001.
11. NIZET, J.L.; PIERARD-FRANCHIMONT, C.; PIERARD, G.E. Influence of the body posture and gravitational forces on shear wave propagation in the skin. Dermatology, v.202, n.2, p.177-180, 2001.
12. PAYE M.; MAC-MARY, S.; ELKHYAT, A.; TARRIT, C.; MERMET, P.; HUMBERT P.H. Use of the Reviscometer for measuring cosmetics-induced skin surface effects. Skin Res. Technol., v.13, n.4, p.343-349, 2007.
13. RAWLINGS, A.V.; HARDING, C.R. Moisturization and skin barrier function. Dermatol. Ther., v.17, Supl.1, p.43-48, 2004.
14. RIEGER, M. Ceramides their promise in skin care. Cosm. Toil., v.111, p.33-45, 1996.
15. ROGIERS, V. Standardized conditions needed for skin surface hydration measurements. Cosm. Toil., v.105, p.76-82, 1990.
16. RUVOLO, E.C.; STAMATAS, G.N.; KOLLIAS, N. Skin viscoelasticity displays site-and age-dependent angular anisotropy. Skin Pharmacol. Physiol., v.20, n.6, p.313-321, 2007.
17. SAVICA, S.; TAMBURIC, S.; SAVIC, M.; CEKIC, N.; MILIC, J.; VULETA, G. Vehicle-controlled effect of urea on normal and SLS-irritated skin. Int. J. Pharm., v.271, n.1-2, p.269-280, 2004.
18. SIVILIA, S.; PARADISI, M.; D'INTINO, G.; FERNANDEZ, M.; PIRONDI, S,; LORENZINI L, CALZA L. Skin homeostasis during inflammation: a role for nerve growth factor. Histol. Histopathol., v.23, p.1-10, 2008.
19. SOMMERFELD B. Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness. Phytomedicine, v.14, n.11, p.711-715, 2007.
20. SUMINO, H.; ICHIKAWA, S.; ABE, M.; ENDO, Y.; ISHIKAWA, O.; URABAYASHI M. Effects of aging, menopause and hormone replacement therapy on forearm skin elasticity in women. J. Am. Geriatr. Soc., v.52, n.6, p.945-949, 2004.
21. TAKEMA, Y.; YORIMOTO, Y.; KAWAI, M.; IMOKAWA, G. Age-related changes in the elastic properties and thickness of human facial skin. Br. J. Dermatol., v.131, n.5, p.641-648, 1994.
22. UHODA, I.; FASKA, N.; ROBERT, C.; CAUWENBERGH, G.; PIÉRARD, G.E. Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. Skin Res. Technol., v.8, n.3, p.164-167, 2002.
23. VERHAEGEN, P.D.; RES, E.M.; VAN ENGELEN, A.; MIDDELKOOP. E.; VAN ZUIJLEN P.P. A reliable,non-invasive measurement tool for anisotropy in normal skin and scar tissue. Skin Res. Technol., v.16, n.3, p.325-331, 2010.
24. VEXLER, A.; POLYANSKY, I.; GORODETSKY, R. Evaluation of skin viscoelasticity and anisotropy by measurement of speed of shear wave propagation with viscoelasticity skin analyzer. J. Investig. Dermatol., v.113, n.5, p.732-739, 1999.
25. ZHANG, L.; FALLA, T.J. Cosmeceuticals and peptides. Clin. Dermatol., v.27, n.5, p.485-494, 2009.