Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

Journal of Experimental Medicine

Volumn 212, Issue 12, 2015, Pages 2015-2025

  van Helden, Mary J ^a,b   Goossens, Steven ^a,b   Daussy, Cécile ^c,d,e,f,g   Mathieu, Anne Laure ^c,d,e,f,g   Faure, Fabrice ^c,d,e,f,g   Marçais, Antoine ^c,d,e,f,g   Vandamme, Niels ^a,b   Farla, Natalie ^a,b   Mayol, Katia ^c,d,e,f,g   Viel, Sébastien ^c,d,e,f,g,h   Degouve, Sophie ^b,c,d,e,f   Debien, Emilie ^c,d,e,f,g   Seuntjens, Eve ⁱ   Conidi, Andrea ^j   Chaix, Julie ^k   Mangeot, Philippe ^c,d,e,f,g   de Bernard, Simon ^l   Buffat, Laurent ^l   Haigh, Jody J ^b,m   Huylebroeck, Danny ^i,j   Lambrecht, Bart N ^a,b,j   Berx, Geert ^a,b   Walzer, Thierry ^c,d,e,f,g   more..

^a Inflammation Research Center   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITÉ DE LYON   (France)

^d INSERM   (France)

^e UNIVERSITÉ DE LYON   (France)

^f CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^g CNRS   (France)

^h HOSPICES CIVILS DE LYON   (France)

ⁱ UNIVERSITY OF LEUVEN   (Belgium)

^j ERASMUS MEDICAL CENTER   (Netherlands)

^k CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^l Altra Bio   (France)

^m MONASH UNIVERSITY   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD146 ANTIGEN; CD27 ANTIGEN; CD39 ANTIGEN; CD56 ANTIGEN; CD57 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 7 RECEPTOR; MESSENGER RNA; NATURAL KILLER CELL RECEPTOR NKG2A; S6 KINASE; STAT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; CYTOKINE; HOMEODOMAIN PROTEIN; REPRESSOR PROTEIN; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; ZFHX1B PROTEIN, MOUSE;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEGRANULATION; ECTOPIC EXPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; GENE CONTROL; GENE DELETION; GENE TARGETING; HUMAN; HUMAN CELL; LUNG METASTASIS; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MELANOMA B16; METASTATIC MELANOMA; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR REJECTION; UPREGULATION; ANIMAL; BONE MARROW; C57BL MOUSE; CELL CULTURE; EXPERIMENTAL MELANOMA; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; BONE MARROW; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; FLOW CYTOMETRY; GENE EXPRESSION; HOMEODOMAIN PROTEINS; HUMANS; KILLER CELLS, NATURAL; MELANOMA, EXPERIMENTAL; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-BOX DOMAIN PROTEINS;

EID: 84962635492     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150809     Document Type: Article

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