The effect of oxytocin on attention to angry and happy faces in chronic depression

BMC Psychiatry

Volumn 16, Issue 1, 2016, Pages

  Domes, Gregor ^a,b   Normann, Claus ^b   Heinrichs, Markus ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Attention; Chronic depression; Dot probe; Facial emotions; Oxytocin; Social perception

Indexed keywords

NEUROPEPTIDE; OXYTOCIN; PLACEBO; OXYTOCIC AGENT;

ARTICLE; ATTENTION; ATTENTIONAL BIAS; AWARENESS; BECK DEPRESSION INVENTORY; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; EMOTION; FACIAL EXPRESSION; FEMALE; HUMAN; MALE; MENTAL DISEASE; NEUROPSYCHIATRY; PSYCHOMETRY; PSYCHOSOCIAL CARE; RANDOMIZED CONTROLLED TRIAL; REACTION TIME; RECOGNITION; SINGLE DRUG DOSE; SOCIAL COGNITION; SOCIAL INTERACTION; STATE TRAIT ANXIETY INVENTORY; ANGER; CHRONIC DISEASE; DRUG EFFECTS; HAPPINESS; INTRANASAL DRUG ADMINISTRATION; MIDDLE AGED; PSYCHOLOGY; SOCIAL BEHAVIOR;

ADMINISTRATION, INTRANASAL; ANGER; ATTENTION; CHRONIC DISEASE; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; FACIAL EXPRESSION; FEMALE; HAPPINESS; HUMANS; MALE; MIDDLE AGED; OXYTOCICS; OXYTOCIN; REACTION TIME; SOCIAL BEHAVIOR;

EID: 84962200723     PISSN: None     EISSN: 1471244X     Source Type: Journal    
DOI: 10.1186/s12888-016-0794-9     Document Type: Article

References (52)

1. Dunner DL. Acute and maintenance treatment of chronic depression. J Clin Psychiatry. 2001;62:10-6.
2. Klein DN. Chronic depression: diagnosis and classification. Curr Dir Psychol Sci. 2010;19:96-100.
3. Brakemeier EL, Engel V, Schramm E, Zobel I, Schmidt T, Hautzinger M, Berger M, Normann C. Feasibility and outcome of cognitive Behavioral Analysis System of Psychotherapy (CBASP) for chronically depressed inpatients: a pilot study. Psychother Psychosom. 2011;80:191-4.
4. Lizardi H, Klein DN, Ouimette PC, Riso LP, Anderson RL, Donaldson SK. Reports of the childhoodhome-environment in early-onset dysthymia and episodic major depression. J Abnorm Psychol. 1995;104:132-9.
5. Kuhnen T, Knappke F, Otto T, Friedrich S, Klein JP, Kahl KG, Huppe M, Sipos V, Schweiger U. Chronic depression: development and evaluation of the luebeck questionnaire for recording preoperational thinking (LQPT). BMC Psychiatry. 2011;11:199.
6. McCullough J. Treatment for chronic depression. Cognitive behavioral analysis system of psychotherapy. New York: Guilford Press; 1994.
7. Domes G, Spenthof I, Radtke M, Isaksson A, Normann C, Heinrichs M. Autistic traits and empathy in chronic vs. episodic depression. J Affect Disord. 2016;195:144-7.
8. Bourke C, Douglas K, Porter R. Processing of facial emotion expression in major depression: a review. Aust N Z J Psychiatry. 2010;44:681-96.
9. Peckham AD, McHugh RK, Otto MW. A meta-analysis of the magnitude of biased attention in depression. Depress Anxiety. 2010;27:1135-42.
10. Hansen CH, Hansen RD. Finding the face in the crowd: an anger superiority effect. J Pers Soc Psychol. 1988;54:917-24.
11. Maratos FA, Mogg K, Bradley BP. Identification of angry faces in the attentional blink. Cognit Emot. 2008;22:1340-52.
12. MacLeod C, Mathews A, Tata P. Attentional bias in emotional disorders. J Abnorm Psychol. 1986;95:15-20.
13. Bar-Haim Y, Lamy D, Pergamin L, Bakermans-Kranenburg MJ, van IJzendoorn MH. Threat-related attentional bias in anxious and nonanxious individuals: a meta-analytic study. Psychol Bull. 2007;133:1-24.
14. Bradley BP, Mogg K, Falla SJ, Hamilton LR. Attentional bias for threatening facial expressions in anxiety: manipulation of stimulus duration. Cognit Emot. 1998;12:737-53.
15. Bradley BP, Mogg K, Millar N, BonhamCarter C, Fergusson E, Jenkins J, Parr M. Attentional biases for emotional faces. Cognit Emot. 1997;11:25-42.
16. Joormann J, Gotlib IH. Selective attention to emotional faces following recovery from depression. J Abnorm Psychol. 2007;116:80-5.
17. Gotlib IH, Krasnoperova E, Yue DN, Joormann J. Attentional biases for negative interpersonal stimuli in clinical depression. J Abnorm Psychol. 2004;113:121-35.
18. Leyman L, De Raedt R, Schacht R, Koster EH. Attentional biases for angry faces in unipolar depression. Psychol Med. 2007;37:393-402.
19. Mogg K, Millar N, Bradley BP. Biases in eye movements to threatening facial expressions in generalized anxiety disorder and depressive disorder. J Abnorm Psychol. 2000;109:695-704.
20. Fox E, Russo R, Bowles R, Dutton K. Do threatening stimuli draw or hold visual attention in subclinical anxiety? J Exp Psychol Gen. 2001;130:681-700.
21. Koster EH, Crombez G, Verschuere B, De Houwer J. Selective attention to threat in the dot probe paradigm: differentiating vigilance and difficulty to disengage. Behav Res Ther. 2004;42:1183-92.
22. Heinrichs M, von Dawans B, Domes G. Oxytocin, vasopressin, and human social behavior. Front Neuroendocrinol. 2009;30:548-57.
23. Meyer-Lindenberg A, Domes G, Kirsch P, Heinrichs M. Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nat Rev Neurosci. 2011;12:524-38.
24. Shahrestani S, Kemp AH, Guastella AJ. The impact of a single administration of intranasal oxytocin on the recognition of basic emotions in humans: a meta-analysis. Neuropsychopharmacology. 2013;38:1929-36.
25. Marsh AA, Yu HH, Pine DS, Blair RJ. Oxytocin improves specific recognition of positive facial expressions. Psychopharmacology (Berl). 2010;209:225-32.
26. Schulze L, Lischke A, Greif J, Herpertz SC, Heinrichs M, Domes G. Oxytocin increases recognition of masked emotional faces. Psychoneuroendocrinology. 2011;36:1378-82.
27. Lischke A, Berger C, Prehn K, Heinrichs M, Herpertz SC, Domes G. Intranasal oxytocin enhances emotion recognition from dynamic facial expressions but leaves eye-gaze unaffected. Psychoneuroendocrinology. 2012;37:475-81.
28. Domes G, Heinrichs M, Michel A, Berger C, Herpertz SC. Oxytocin improves "mind-reading" in humans. Biol Psychiatry. 2007;61:731-3.
29. Domes G, Kumbier E, Heinrichs M, Herpertz SC. Oxytocin promotes facial emotion recognition and amygdala reactivity in adults with Asperger syndrome. Neuropsychopharmacology. 2014;39:698-706.
30. Guastella AJ, Einfeld SL, Gray KM, Rinehart NJ, Tonge BJ, Lambert TJ, Hickie IB. Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol Psychiatry. 2010;67:692-4.
31. Pedersen CA, Gibson CM, Rau SW, Salimi K, Smedley KL, Casey RL, Leserman J, Jarskog LF, Penn DL. Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophrenia. Schizophr Res. 2011;132:50-3.
32. Averbeck BB, Bobin T, Evans S, Shergill SS. Emotion recognition and oxytocin in patients with schizophrenia. Psychol Med. 2012;42:259-66.
33. Domes G, Sibold M, Schulze L, Lischke A, Herpertz SC, Heinrichs M. Intranasal oxytocin increases covert attention to positive social cues. Psychol Med. 2013;43:1747-53.
34. Ellenbogen MA, Linnen AM, Grumet R, Cardoso C, Joober R. The acute effects of intranasal oxytocin on automatic and effortful attentional shifting to emotional faces. Psychophysiology. 2012;49:128-37.
35. Domes G, Steiner A, Porges SW, Heinrichs M. Oxytocin differentially modulates eye gaze to naturalistic social signals of happiness and anger. Psychoneuroendocrinology. 2013;38:1198-202.
36. Gamer M, Zurowski B, Buchel C. Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans. Proc Natl Acad Sci U S A. 2010;107:9400-5.
37. Guastella AJ, Mitchell PB, Dadds MR. Oxytocin increases gaze to the eye region of human faces. Biol Psychiatry. 2008;63:3-5.
38. MacDonald K, MacDonald TM, Brune M, Lamb K, Wilson MP, Golshan S, Feifel D. Oxytocin and psychotherapy: a pilot study of its physiological, behavioral and subjective effects in males with depression. Psychoneuroendocrinology. 2013;38:2831-43.
39. Scantamburlo G, Ansseau M, Geenen V, Legros JJ. Intranasal oxytocin as an adjunct to escitalopram in major depression. J Neuropsychiatry Clin Neurosci. 2011;23, E5.
40. Woody ML, Owens M, Burkhouse KL, Gibb BE. Selective attention toward angry faces and risk for major depressive disorder in women: converging evidence from retrospective and prospective analyses. Clin Psychol Sci. 2015; Epub ahead of print. doi: 10.1177/2167702615581580.
41. Beck AT, Hautzinger M, Bailer M, Worall H, Keller F. BDI Beck-Depressions-Inventar [BDI Beck Depression Inventory]. Göttingen: Hogrefe; 1995.
42. Laux L, Glanzmann P, Schaffner P, Spielberger CD. STAI Das State-Trait-Angstinventar [State-Trait Anxiety Inventory]. Göttingen: Hogrefe; 1981.
43. Steyer R, Schwenkmezger P, Notz P, Eid M. Der Mehrdimensionale Befindlichkeitsfragebogen MDBF [Multidimensional mood questionnaire]. Göttingen: Hogrefe; 1997.
44. Lundqvist D, Flykt A, Ohman A. The Karolinska Directed Emotional Faces (KDEF). Stockholm: Department of Clinical Neurosciences, Psychology Section; 1998.
45. Gotlib IH, Kasch KL, Traill S, Joormann J, Arnow BA, Johnson SL. Coherence and specificity of information-processing biases in depression and social phobia. J Abnorm Psychol. 2004;113:386-98.
46. Domes G, Schulze L, Herpertz SC. Emotion recognition in borderline personality disorder-a review of the literature. J Pers Disord. 2009;23:6-19.
47. Fenske S, Lis S, Liebke L, Niedtfeld I, Kirsch P, Mier D. Emotion recognition in borderline personality disorder: effects of emotional information on negative bias. Borderline Personal Disord Emot Dysregul. 2015;2:10.
48. Kanat M, Heinrichs M, Domes G. Oxytocin and the social brain: neural mechanisms and perspectives in human research. Brain Res. 2014;1580:160-71.
49. Heinrichs M, Domes G. Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans. Prog Brain Res. 2008;170:337-50.
50. Domes G, Heinrichs M, Kumbier E, Grossmann A, Hauenstein K, Herpertz SC. Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder. Biol Psychiatry. 2013;74:164-71.
51. Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, Sirigu A. Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proc Natl Acad Sci U S A. 2010;107:4389-94.
52. Bartz JA, Hollander E. Oxytocin and experimental therapeutics in autism spectrum disorders. Prog Brain Res. 2008;170:451-62.