Impact of depressive symptoms and hepatic encephalopathy on health-related quality of life in cirrhotic hepatitis C patients

Metabolic Brain Disease

Volumn 31, Issue 4, 2016, Pages 869-880

  Barboza, Katherine C ^a   Salinas, Lilian M ^a   Sahebjam, Farhad ^a   Jesudian, Arun B ^b   Weisberg, Ilan L ^a   Sigal, Samuel H ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

Cirrhosis; Depression; Fatigue; Health Related Quality of Life; Hepatic Encephalopathy; Hepatitis C

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; DAYTIME SOMNOLENCE; DEPRESSION; DISEASE SEVERITY; FATIGUE; FEMALE; HEPATIC ENCEPHALOPATHY; HEPATITIS C; HUMAN; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PROSPECTIVE STUDY; PSYCHOMETRY; QUALITY OF LIFE; AGED; COMPLICATION; HEALTH STATUS; PSYCHOLOGY;

AGED; DEPRESSION; FEMALE; HEALTH STATUS; HEPATIC ENCEPHALOPATHY; HEPATITIS C; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; QUALITY OF LIFE;

EID: 84962167825     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-016-9817-y     Document Type: Article

References (73)

1. Ahluwalia V et al. (2015) Correction of hyponatraemia improves cognition, quality of life, and brain oedema in cirrhosis. J Hepatol 62:75–82. doi:10.1016/j.jhep.2014.07.033
2. Albrecht J (2010) Hepatic encephalopathy in our genes? Ann Intern Med 153(5):335–336
3. Arguedas MR, DeLawrence TG, McGuire BM (2003) Influence of hepatic encephalopathy on health-related quality of life in patients with cirrhosis. Dig Dis Sci 48:1622–1626
4. Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WI, Alter MJ (2006) The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 144:705–714
5. Bajaj JS et al. (2012) Cognitive performance as a predictor of hepatic encephalopathy in pretransplant patients with cirrhosis receiving psychoactive medications: a prospective study. Liver Transpl 18:1179–1187. doi:10.1002/lt.23484
6. Bautovich A, Katz I, Smith M, Loo CK, Harvey SB (2014) Depression and chronic kidney disease: A review for clinicians. Aust N Z J Psychiatry 48:530–541. doi:10.1177/0004867414528589
7. Beck AT, Guth D, Steer RA, Ball R (1997) Screening for major depression disorders in medical inpatients with the Beck Depression Inventory for Primary Care. Behav Res Ther 35:785–791. doi:10.1016/S0005-7967(97)00025-9
8. Bergeron M, Reader TA, Layrargues GP, Butterworth RF (1989) Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy. Neurochem Res 14:853–859
9. Bianchi G et al. (2005) Psychological status and depression in patients with liver cirrhosis. Dig Liver Dis 37:593–600. doi:10.1016/j.dld.2005.01.020
10. Bilgic A, Akman B, Sezer S, Ozisik L, Arat Z, Ozdemir FN, Haberal M (2008) Predictors for quality of life in continuous ambulatory peritoneal dialysis patients. Nephrology 13:587–592. doi:10.1111/j.1440-1797.2008.00970.x
11. Bonkovsky HL, Snow KK, Malet PF, et al. (2007) HALT-C Trial Group. health-related quality of life in patients with chronic hepatitis C and advanced fibrosis. J Hepatol 46(3):420–431
12. Butterworth RF (1998) Alterations of neurotransmitter-related gene expression in human and experimental portal-systemic encephalopathy. Metab Brain Dis 13(4):337–349
13. Butterworth RF (2000) Complications of cirrhosis III. hepatic encephalopathy. journal of hepatology 32. Supplement 1:171–180. doi:10.1016/S0168-8278(00)80424-9
14. Butterworth RF (2008) Pathophysiology of hepatic encephalopathy: the concept of synergism. Hepatol Res 38(suppl 1):S116–S121
15. Chong CA, Gulamhussein A, Heathcote EJ, Lilly L, Sherman M, Naglie G, et al. (2003) Health-state utilities and quality of life in hepatitis C patients. Am J Gastroenterol 98:630–638
16. Conn HO (1977) Trailmaking and number-connection tests in the assessment of mental state in portal systemic encephalopathy. Am J Dig Dis 22:541–550
17. Cordoba J, Flavia M, Jacas C, Sauleda S, Esteban JI, Vargas V, et al. (2003) Quality of life and cognitive function in hepatitis C at different stages of liver disease. J Hepatol 39:231–238
18. Dan AA, Martin LM, Crone C, et al. (2006) Depression, anemia and health-related quality of life in chronic hepatitis C. J Hepatol 44(3):491–498
19. Delis DC, Kaplan E, Kramer JH (2001) Delis-Kaplan Executive Function System (D-KEFS) technical manual San Antonio. The Psychological Corporation, TX
20. Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, Blei AT (2002) Hepatic encephalopathy—definition, nomenclature, diagnosis, and quantification: final report of the Working Party at the 11th world congresses of gastroenterology, Vienna, 1998 Hepatology 35:716–721 doi:10.1053/jhep.2002.31250
21. Ferrari AJ et al. (2013) Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Med 10:e1001547. doi:10.1371/journal.pmed.1001547
22. Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF (1994) Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis 18:S79–S83. doi:10.1093/clinids/18.Supplement_1.S79
23. Fontana RJ, Bieliauskas LA, Back-Madruga C, et al. (2005) Cognitive function in hepatitis C patients with advanced fibrosis enrolled in the HALT-C trial. J Hepatol 43(4):614–622
24. Fontana RJ et al. (2008) Changes in mood states and biomarkers during peginterferon and ribavirin treatment of chronic hepatitis C. Am J Gastroenterol 103:2766–2775
25. Fritz E, Hammer J (2009) Gastrointestinal symptoms in patients with liver cirrhosis are linked to impaired quality of life and psychological distress. Eur J Gastroenterol Hepatol 21(4):460–465
26. Ghany MG, Strader DB, Thomas DL, Seeff LB, American Association for the Study of Liver Diseases (2009) Diagnosis, management, and treatment of hepatitis C: an update. Hepatology 49:1335–1374
27. Glassman AH, Bigger J Jr, Gaffney M (2009) Psychiatric characteristics associated with long-term mortality among 361 patients having an acute coronary syndrome and major depression: seven-year follow-up of sadhart participants. Arch Gen Psychiatry 66:1022–1029. doi:10.1001/archgenpsychiatry.2009.121
28. Gralnek IM et al. (2000) Development and evaluation of the liver disease quality of life instrument in persons with advanced, chronic liver disease[mdash]the LDQOL 1.0. Am J Gastroenterol 95:3552–3565
29. Gutteling JJ, de Man RA, Busschbach JJV, Darlington A-SE (2007) Health-related quality of life and psychological correlates in patients listed for liver transplantation. Hepatol Int 1:437–443. doi:10.1007/s12072-007-9035-0
30. Häuser W, Holtmann G, Grandt D (2004) Determinants of health-related quality of life in patients with chronic liver diseases. Clin Gastroenterol Hepatol 2:157–163. doi:10.1016/S1542-3565(03)00315-X
31. IBM Corp. (2012) IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp
32. Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale Sleep 14:540–545
33. Kanwal F, Hays RD, Kilbourne AM, Dulai GS, Gralnek IM (2004) Are physician-derived disease severity indices associated with health-related quality of life in patients with end-stage liver disease. Am J Gastroenterol 99:1726–1732
34. Kanwal F et al. (2009) Health-related quality of life predicts mortality in patients with advanced chronic liver disease. Clin Gastroenterol Hepatol 7:793–799. doi:10.1016/j.cgh.2009.03.013
35. Kim WR, Brown RS, Tarrault NA, El-Serag H (2002) Burden of liver disease in the United States: summary of a workshop. Hepatology 36:227–242
36. Kim WR, Terrault NA, Pedersen RA, et al. (2009) Trends in waiting list registration for liver transplantation for viral hepatitis in the United States. Gastroenterology 137:1680–1686
37. Lavretsky H et al. (2010) Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study. Am J Psychiatr 167:589–597. doi:10.1176/appi.ajp.2009.09020280
38. Le Strat Y, Le Foll B, Dubertret C (2014) Major depression and suicide attempts in patients with liver disease in the United States Liver International: n/a-n/a doi:10.1111/liv.12612
39. Lee K, Otgonsuren M, Younoszai Z, Mir HM, Younossi ZM (2013) Association of chronic liver disease with depression: A population-based study. Psychosomatics 54:52–59. doi:10.1016/j.psym.2012.09.005
40. Les I et al. (2010) Quality of life in cirrhosis is related to potentially treatable factors. Eur J Gastroenterol Hepatol 22:221–227. doi:10.1097/MEG.0b013e3283319975
41. Lin EHB et al. (2009) Depression and increased mortality in diabetes: unexpected causes of death. Ann Fam Med 7:414–421. doi:10.1370/afm.998
42. Loria A, Escheik C, Gerber NL, Younossi ZM (2013) Quality of life in cirrhosis Current Gastroenterology Reports Jan;15(1):301. doi:10.1007/s11894-012-0301-5
43. Lozeva V, Montgomery JA, Tuomisto L, Rocheleau B, Pannunzio M, Huet P-M, Butterworth RF (2004) Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis. J Hepatol 40:742–748. doi:10.1016/j.jhep.2004.01.003
44. Marchesini G et al. (2001) Factors associated with poor health-related quality of life of patients with cirrhosis. Gastroenterology 120:170–178. doi:10.1053/gast.2001.21193
45. Massie MJ (2004) Prevalence of depression in patients with cancer. JNCI Monographs 2004:57–71. doi:10.1093/jncimonographs/lgh014
46. Meltzer HY (1990) Role of serotonin in depression. Ann N Y Acad Sci 600:486–499. doi:10.1111/j.1749-6632.1990.tb16904.x
47. Meltzer HY, Perline R, Tricou B, Lowy M, Robertson A (1984) Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders: Ii. relation to suicide, psychosis, and depressive symptoms. Arch Gen Psychiatry 41:379–387. doi:10.1001/archpsyc.1984.01790150069010
48. Moscucci F, Nardelli S, Pentassuglio I, Pasquale C, Ridola L, Merli M, Riggio O (2011) Previous overt hepatic encephalopathy rather than minimal hepatic encephalopathy impairs health-related quality of life in cirrhotic patients. Liver Int 31:1505–1510. doi:10.1111/j.1478-3231.2011.02598.x
49. Mullish BH, Kabir MS, Thursz MR, Dhar A (2014) Review article: depression and the use of antidepressants in patients with chronic liver disease or liver transplantation. Aliment Pharmacol Ther 40:880–892. doi:10.1111/apt.12925
50. Nardelli S et al. (2013) Depression, anxiety and alexithymia symptoms are major determinants of health related quality of life (HRQoL) in cirrhotic patients. Metab Brain Dis 28:239–243. doi:10.1007/s11011-012-9364-0
51. Onitilo AA, Nietert PJ, Egede LE (2006) Effect of depression on all-cause mortality in adults with cancer and differential effects by cancer site. Gen Hosp Psychiatry 28:396–402. doi:10.1016/j.genhosppsych.2006.05.006
52. Orrù MG, Pariante CM (2005) Depression and liver diseases. Dig Liver Dis 37:564–565. doi:10.1016/j.dld.2005.04.003
53. Pérez-Stable EJ, Miranda J, Muñoz RF, Ying Y (1990) Depression in medical outpatients: underrecognition and misdiagnosis. Arch Intern Med 150:1083–1088. doi:10.1001/archinte.1990.00390170113024
54. Pirkola S et al. (2009) General health and quality-of-life measures in active, recent, and comorbid mental disorders: a population-based health 2000 study. Compr Psychiatry 50:108–114. doi:10.1016/j.comppsych.2008.06.003
55. Prasad S, Dhiman RK, Duseja A, Chawla YK, Sharma A, Agarwal R (2007) Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy. Hepatology 45(3):549–559. doi:10.1002/hep.21533
56. Prince MI, James OFW, Holland NP, Jones DEJ (2000) Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use. J Hepatol 32:368–373. doi:10.1016/S0168-8278(00)80385-2
57. Rodger AJ, Roberts S, Lanigan A, Bowden S, Crofts N (2000) Assessment of long-term outcomes of community- acquired hepatitis C infection in a cohort with sera stored from 1971 to 1975. Hepatology 32:582–587
58. Schomerus H, Hamster W (2001) Quality of life in cirrhotics with minimal hepatic encephalopathy. Metab Brain Dis 16:37–41
59. Shawcross DL, Wright G, Olde Damink SW, et al. (2007) Role of ammonia and inflammation in minimal hepatic encephalopathy. Metab Brain Dis 22(1):125–138
60. Simard EP, Ward EM, Siegel R, Jemal A (2012) Cancers with increasing incidence trends in the United States: 1999 through 2008. CA Cancer J Clin 62:128
61. Singh N, Gayowski T, Wagener MM, Marino IR (1997a) Depression in patients with cirrhosis. Impact Outcome Dig Dis Sci 42:1421–1427
62. Singh N, Gayowski T, Wagener MM, Marino IR (1997b) Vulnerability to psychologic distress and depression in patients with end-stage liver disease due to hepatitis C virus. Clin Transpl 11:406–411
63. Stafford L, Berk M, Reddy P, Jackson HJ (2007) Comorbid depression and health-related quality of life in patients with coronary artery disease. J Psychosom Res 62:401–410. doi:10.1016/j.jpsychores.2006.12.009
64. Stewart CA, Smith GE (2007) Minimal hepatic encephalopathy. Nat Clin Pract Gastroenterol Hepatol 4(12):677–685. doi:10.1038/ncpgasthep0999
65. Tate D et al. (2003) The impact of apathy and depression on quality of life in patients infected with HIV AIDS Patient Care and STDs 17:115–120 doi:10.1089/108729103763807936
66. Turvey CL, Klein DM, Pies CJ, Arndt S (2003) Attitudes about impairment and depression in elders suffering from chronic heart failure. Int J Psychiatry Med 33:117–132. doi:10.2190/7ddc-aehy-t72u-47gu
67. van Dooren FEP, Nefs G, Schram MT, Verhey FRJ, Denollet J, Pouwer F (2013) Depression and risk of mortality in people with diabetes mellitus: A systematic review and meta-analysis. PLoS One 8:e57058. doi:10.1371/journal.pone.0057058
68. Wallen J, Pincus H, Goldman HH, Marcus SE (1987) Psychiatric consultations in short-term general hospitals. Arch Gen Psychiatry 44:163–168. doi:10.1001/archpsyc.1987.01800140073010
69. Ware JE, Snow KK, Kosinski M, Gandek B, Institute NEMCHH (1993) SF-36 health survey: manual and interpretation guide. The Health Institute, New England Medical Center Hospitals, Boston, MA
70. Wechsler D (1997) Wechsler adult intelligence scale, third edition: administration and scoring manual San Antonio. The Psychological Corporation, TX
71. Weissenborn K, Rückert N, Hecker H, Manns MP (1998) The number connection tests A and B: interindividual variability and use for the assessment of early hepatic encephalopathy. J Hepatol 28:646–653. doi:10.1016/S0168-8278(98)80289-4
72. Weissenborn K, Giewekemeyer K, Heidenreich S, Bokemeyer M, Berding G, Ahl B (2005) Attention, memory, and cognitive function in hepatic encephalopathy. Metab Brain Dis 20:359–367
73. Youssef NA et al. (2013) Associations of depression, anxiety and antidepressants with histological severity of nonalcoholic fatty liver disease. Liver Int 33:1062–1070. doi:10.1111/liv.12165