Human Genetic Variability Contributes to Postoperative Morphine Consumption

Journal of Pain

Volumn 17, Issue 5, 2016, Pages 628-636

  De Gregori, Manuela ^a,b   Diatchenko, Luda ^b,c   Ingelmo, Pablo M ^b,d   Napolioni, Valerio ^b,e   Klepstad, Pal ^b,f,g   Belfer, Inna ^b,h   Molinaro, Valeria ⁱ   Garbin, Giulia ⁱ   Ranzani, Guglielmina N ⁱ   Alberio, Giovanni ^j   Normanno, Marco ^j   Lovisari, Federica ^j   Somaini, Marta ^j   Govoni, Stefano ^b,i   Mura, Elisa ⁱ   Bugada, Dario ^b,i   Niebel, Thekla ^b,i   Zorzetto, Michele ^a   De Gregori, Simona ^a   Molinaro, Mariadelfina ^a   Fanelli, Guido ^b   Allegri, Massimo ^b   more..

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c MCGILL UNIVERSITY   (Canada)

^d MONTREAL CHILDREN S HOSPITAL   (Canada)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^g TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^h UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF PAVIA   (Italy)

^j SAN GERARDO HOSPITAL   (Italy)

more..

Author keywords

Acute postoperative pain; genetic variability; genetic variants combination; OPRM1 haplotype; postoperative opioid consumption

Indexed keywords

CATECHOL METHYLTRANSFERASE; ESTROGEN RECEPTOR ALPHA; GLUCURONOSYLTRANSFERASE 2B7; MORPHINE; MU OPIATE RECEPTOR; ESTROGEN RECEPTOR ALPHA, HUMAN; NARCOTIC ANALGESIC AGENT; OPRM1 PROTEIN, HUMAN;

ABDOMINAL SURGERY; ADULT; AGED; ARTICLE; CAUCASIAN; CLINICAL TRIAL; ESR1 GENE; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OPRM1 GENE; PAIN INTENSITY; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; RATING SCALE; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; GENETICS; GENOTYPE; MIDDLE AGED; OUTCOME ASSESSMENT; PAIN, POSTOPERATIVE; PHARMACOGENETIC TESTING; TIME FACTOR; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CATECHOL O-METHYLTRANSFERASE; ESTROGEN RECEPTOR ALPHA; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MORPHINE; OUTCOME ASSESSMENT (HEALTH CARE); PAIN, POSTOPERATIVE; PHARMACOGENOMIC TESTING; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, OPIOID, MU; TIME FACTORS; YOUNG ADULT;

EID: 84962128848     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2016.02.003     Document Type: Article

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