In vitro release of nicotine from chewing gum formulations

Dissolution Technologies

Volumn 11, Issue 2, 2004, Pages 12-15

  Morjaria, Yamini ^a   Irwin, William J ^a   Barnett, Paul X ^b   Chan, Rick S ^c   Conway, Barbara R ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE;

ARTICLE; CHEWING GUM; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; FLOW RATE; IN VITRO STUDY; MASTICATION; MEDICAL LITERATURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TABLET COMPRESSION;

EID: 84962076686     PISSN: 1521298X     EISSN: None     Source Type: Journal    
DOI: 10.14227/DT110204P12     Document Type: Article

References (7)

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2. LL Christrup and N Møeller," Chewing gum as a drug delivery system". Arch Pharm Chem, Sci Ed, 14: 30-36, 1986.
3. JN Rider, EL Brunson, WG Chambliss, RW Cleary, AH Hikal, PH Rider, LA Walker, CM Wyandt and AB Jones, "Development and evaluation of a novel dissolution apparatus for medicated chewing gum products." Pharm Res, 9: 255-260, 1992.
4. C Kvist, S-B Andersson, S Fors, B Wennergren and J Berglund," Apparatus for studying in vitro release from medicated chewing gums." Int J Pharm, 189: 57-65, 1999.
5. European Pharmacopoeia 4th Edition-2002, General Chapter 2. 9. 25," Chewing gum, Medicated, Drug Release From," pp 227-228, Directorate for the Quality of Medicines of the Council of Europe, Strasbourg, 2001.
6. S Parker, D Martin and M Braden," Soft acrylic resin materials containing a polymerisable plasticiser II: Water absorption characteristics." Biomaterials, 20: 55-60, 1999.
7. Y Mistry, WJ Irwin, BR Conway, P Barnett, T Grattan and RS Chan," In vitro release of nicotine from commercially available nicotine gums using the European Pharmacopoeia apparatus." J Pharm Pharmacol 53S: 197, 2001.