Analysis of amino acid substitutions in AraC variants that respond to triacetic acid lactone

Protein Science

Volumn 25, Issue 4, 2016, Pages 804-814

  Frei, Christopher S ^a   Wang, Zhiqing ^a   Qian, Shuai ^a   Deutsch, Samuel ^b   Sutter, Markus ^b   Cirino, Patrick C ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b DOE JOINT GENOME INSTITUTE   (United States)

Author keywords

AraC; biosensor; cooperative residues; crystal structure; directed evolution; FACS; high throughput screening; molecular reporter; regulatory protein

Indexed keywords

ACETIC ACID DERIVATIVE; AMINO ACID; ARAC PROTEIN; LACTONE; LACTONE DERIVATIVE; TRIACETIC ACID LACTONE; UNCLASSIFIED DRUG; ARAC PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; PYRONE DERIVATIVE;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BIOSENSOR; CRYSTAL STRUCTURE; CRYSTALLIZATION; ESCHERICHIA COLI; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; SCREENING; X RAY DIFFRACTION; BINDING SITE; CHEMISTRY; GENE EXPRESSION REGULATION; GENE LIBRARY; GENETICS; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR MODEL; RANDOMIZATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; ARAC TRANSCRIPTION FACTOR; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENE LIBRARY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PYRONES; RANDOM ALLOCATION;

EID: 84962041258     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2873     Document Type: Article

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