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Volumn 2016, Issue 3, 2016, Pages

Long-term effects of weight-reducing drugs in people with hypertension

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANTIOBESITY AGENT; LIRAGLUTIDE; LORCASERIN; NALTREXONE; PHENTERMINE PLUS TOPIRAMATE; PLACEBO; RIMONABANT; SIBUTRAMINE; TETRAHYDROLIPSTATIN; ANOREXIGENIC AGENT; CYCLOBUTANE DERIVATIVE; FRUCTOSE; LACTONE; PHENTERMINE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; TOPIRAMATE;

EID: 84961875595     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD007654.pub4     Document Type: Review
Times cited : (64)

References (196)
  • 1
    • 0036854640 scopus 로고    scopus 로고
    • Orlistat improves blood pressure control in obese subjects with treated but inadequately controlled hypertension
    • Bakris G, Calhoun D, Egan B, Hellmann C, Dolker M, Kingma I, et al. Orlistat improves blood pressure control in obese subjects with treated but inadequately controlled hypertension. Journal of Hypertension 2002;20(11):2257-67.
    • (2002) Journal of Hypertension , vol.20 , Issue.11 , pp. 2257-2267
    • Bakris, G.1    Calhoun, D.2    Egan, B.3    Hellmann, C.4    Dolker, M.5    Kingma, I.6
  • 2
    • 17144415564 scopus 로고    scopus 로고
    • Sufficient weight reduction decreases cardiovascular complications in diabetic patients with the metabolic syndrome: A randomized study of orlistat as an adjunct to lifestyle changes (diet and exercise)
    • Cocco G, Pandolfi S, Rousson V. Sufficient weight reduction decreases cardiovascular complications in diabetic patients with the metabolic syndrome: A randomized study of orlistat as an adjunct to lifestyle changes (diet and exercise). Heart Drug 2005;5(2):68-74.
    • (2005) Heart Drug , vol.5 , Issue.2 , pp. 68-74
    • Cocco, G.1    Pandolfi, S.2    Rousson, V.3
  • 3
    • 84887233782 scopus 로고    scopus 로고
    • Weight loss and improvements in cardiometabolic outcomes with extended-release phentermine/topiramate treatment in overweight/obese subjects with type 2 diabetes
    • EMBASE: 70888716]
    • Astrup AV, Oppert JM, Peterson CA. Weight loss and improvements in cardiometabolic outcomes with extended-release phentermine/topiramate treatment in overweight/obese subjects with type 2 diabetes. Diabetologia 2012;55(Suppl1):S284-S285. [EMBASE: 70888716]
    • (2012) Diabetologia , vol.55 , pp. S284-S285
    • Astrup, A.V.1    Oppert, J.M.2    Peterson, C.A.3
  • 4
    • 85027091167 scopus 로고    scopus 로고
    • Reduction of cardiovascular risk factors by magnitude of weight loss in obese and overweight subjects with >2 comorbidities
    • [EMBASE: 71292986]
    • Cheskin J, Bowden CH. Reduction of cardiovascular risk factors by magnitude of weight loss in obese and overweight subjects with >2 comorbidities. Journal of General Internal Medicine 2013;28(Suppl1):S168. [EMBASE: 71292986]
    • (2013) Journal of General Internal Medicine , vol.28 , pp. S168
    • Cheskin, J.1    Bowden, C.H.2
  • 5
    • 85027091034 scopus 로고    scopus 로고
    • Improved cardiometabolic risk factors in overweight/obese subjects receiving controlled-release phentermine/topiramate (PHEN/TPM CR)
    • [EMBASE: 70799295]
    • Cheskin LJ, Peterson CA. Improved cardiometabolic risk factors in overweight/obese subjects receiving controlled-release phentermine/topiramate (PHEN/TPM CR). Diabetes 2012;61(Suppl1):A710. [EMBASE: 70799295]
    • (2012) Diabetes , vol.61 , pp. A710
    • Cheskin, L.J.1    Peterson, C.A.2
  • 6
    • 84924976176 scopus 로고    scopus 로고
    • Weight loss and cardiovascular risk reduction over 2 years with controlled-release phentermine-topiramate
    • EMBASE: 70400222]
    • Davidson M, Bowden CH, Day WW. Weight loss and cardiovascular risk reduction over 2 years with controlled-release phentermine-topiramate. Journal of the American College of Cardiology 2011;57(14, Supplement):E545. [EMBASE: 70400222]
    • (2011) Journal of the American College of Cardiology , vol.57 , Issue.14 , pp. E545
    • Davidson, M.1    Bowden, C.H.2    Day, W.W.3
  • 7
    • 84875854090 scopus 로고    scopus 로고
    • Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index >27 kg/m(2)
    • PUBMED: 23375187]
    • Davidson MH, Tonstad S, Oparil S, Schwiers M, Day WW, Bowden CH. Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index >27 kg/m(2). American Journal of Cardiology 2013;111(8):1131-8. [PUBMED: 23375187]
    • (2013) American Journal of Cardiology , vol.111 , Issue.8 , pp. 1131-1138
    • Davidson, M.H.1    Tonstad, S.2    Oparil, S.3    Schwiers, M.4    Day, W.W.5    Bowden, C.H.6
  • 8
    • 84961894157 scopus 로고    scopus 로고
    • Weight loss and improvements in blood pressure (BP) status associated with phentermine and topiramate extended-release (PHEN/TPM ER) treatment in obese and overweight adults
    • EMBASE: 71300090]
    • Finer N, Jordan J, Dvorak R. Weight loss and improvements in blood pressure (BP) status associated with phentermine and topiramate extended-release (PHEN/TPM ER) treatment in obese and overweight adults. Obesity Facts 2013;6(Suppl1):45. [EMBASE: 71300090]
    • (2013) Obesity Facts , vol.6 , pp. 45
    • Finer, N.1    Jordan, J.2    Dvorak, R.3
  • 9
    • 84961933774 scopus 로고    scopus 로고
    • Magnitude of weight loss experienced with a low-dose, controlled-release formulation of phentermine/topiramate (PHEN/TPM) may drive degree of cardiometabolic benefit
    • Conference Publication, EMBASE: 71602039]
    • Gadde K, Najarian T, Day WW. Magnitude of weight loss experienced with a low-dose, controlled-release formulation of phentermine/topiramate (PHEN/TPM) may drive degree of cardiometabolic benefit. Diabetes 2010;Conference Publication:(var. pagings). [EMBASE: 71602039]
    • (2010) Diabetes
    • Gadde, K.1    Najarian, T.2    Day, W.W.3
  • 10
    • 85027091015 scopus 로고    scopus 로고
    • 12-month weight loss and antihypertensive benefits with PHEN/TPM in overweight and obese subjects with hypertension
    • EMBASE: 70349685]
    • Gadde K, Peterson C, Troupin B, Day WW. 12-month weight loss and antihypertensive benefits with PHEN/TPM in overweight and obese subjects with hypertension. European Journal of Cardiovascular Prevention and Rehabilitation 2010;17(2 Suppl):S2. [EMBASE: 70349685]
    • (2010) European Journal of Cardiovascular Prevention and Rehabilitation , vol.17 , Issue.2 Suppl , pp. S2
    • Gadde, K.1    Peterson, C.2    Troupin, B.3    Day, W.W.4
  • 11
    • 79954561234 scopus 로고    scopus 로고
    • Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial.[Erratum appears in Lancet. 2011 Apr 30;377(9776):1494]
    • PUBMED: 21481449]
    • Gadde KM, Allison DB, Ryan DH, Peterson CA, Troupin B, Schwiers ML, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial.[Erratum appears in Lancet. 2011 Apr 30;377(9776):1494]. The Lancet 2011;377(9774):1341-52. [PUBMED: 21481449]
    • (2011) The Lancet , vol.377 , Issue.9774 , pp. 1341-1352
    • Gadde, K.M.1    Allison, D.B.2    Ryan, D.H.3    Peterson, C.A.4    Troupin, B.5    Schwiers, M.L.6
  • 12
    • 84886364834 scopus 로고    scopus 로고
    • Low-dose, controlled-release phentermine/topiramate for reduction of weight, related risks in overweight/obese adults with >2 comorbidities
    • [EMBASE: 70226591]
    • Gadde KM, Day WW. Low-dose, controlled-release phentermine/topiramate for reduction of weight, related risks in overweight/obese adults with >2 comorbidities. Obesity Reviews 2010;11(Suppl1):42-3. [EMBASE: 70226591]
    • (2010) Obesity Reviews , vol.11 , pp. 42-43
    • Gadde, K.M.1    Day, W.W.2
  • 13
    • 85027091196 scopus 로고    scopus 로고
    • Once-daily, low-dose, controlled-release phentermine/topiramate results in significant clinical improvements in overweight/obese patients with type 2 diabetes
    • EMBASE: 70262814]
    • Garvey W T, Troupin B, Day W W. Once-daily, low-dose, controlled-release phentermine/topiramate results in significant clinical improvements in overweight/obese patients with type 2 diabetes. Diabetologia 2010;53(1 Supplement):S308. [EMBASE: 70262814]
    • (2010) Diabetologia , vol.53 , Issue.1 , pp. S308
    • Garvey, W.T.1    Troupin, B.2    Day, W.W.3
  • 14
    • 84961896973 scopus 로고    scopus 로고
    • Changes in insulin sensitivity in overweight/obese patients treated with low-dose, controlled-release phentermine/topiramate (PHEN/TPM)
    • Conference Publication, EMBASE: 71602034]
    • Garvey WT, Gadde K, Tam P, Peterson C. Changes in insulin sensitivity in overweight/obese patients treated with low-dose, controlled-release phentermine/topiramate (PHEN/TPM). Diabetes 2010;Conference Publication:(var. pagings). [EMBASE: 71602034]
    • (2010) Diabetes
    • Garvey, W.T.1    Gadde, K.2    Tam, P.3    Peterson, C.4
  • 15
    • 84961896973 scopus 로고    scopus 로고
    • Improvements in dyslipidemia and other cardiometabolic disease risk factors with low-dose, controlled-release phentermine/topiramate (PHEN/TPM)
    • Conference Publication, (var pagings), EMBASE: 71601293]
    • Garvey WT, Gadde K, Wilson LF, Peterson C. Improvements in dyslipidemia and other cardiometabolic disease risk factors with low-dose, controlled-release phentermine/topiramate (PHEN/TPM). Diabetes 2010;Conference Publication:(var. pagings). [EMBASE: 71601293]
    • (2010) Diabetes
    • Garvey, W.T.1    Gadde, K.2    Wilson, L.F.3    Peterson, C.4
  • 16
    • 84875371277 scopus 로고    scopus 로고
    • Weight loss with controlled-release phentermine/topiramate (PHEN/TPM CR) reverses metabolic syndrome (MetS) and improves associated traits
    • EMBASE: 70629626]
    • Garvey WT, Henry R R, Peterson C A, Bowden C H. Weight loss with controlled-release phentermine/topiramate (PHEN/TPM CR) reverses metabolic syndrome (MetS) and improves associated traits. Diabetes 2011;60(Suppl1):A506. [EMBASE: 70629626]
    • (2011) Diabetes , vol.60 , pp. A506
    • Garvey, W.T.1    Henry, R.R.2    Peterson, C.A.3    Bowden, C.H.4
  • 17
    • 84961887372 scopus 로고    scopus 로고
    • Obesity treatment-induced weight loss improves resting blood pressure and reduces progression from prehypertension to hypertension in overweight/obese adults
    • (12 Meeting Abstracts), EMBASE: 71026610]
    • Gupta AK, Church T, Day WW. Obesity treatment-induced weight loss improves resting blood pressure and reduces progression from prehypertension to hypertension in overweight/obese adults. Circulation 2013;127:(12 Meeting Abstracts). [EMBASE: 71026610]
    • (2013) Circulation , vol.127
    • Gupta, A.K.1    Church, T.2    Day, W.W.3
  • 18
    • 85027090416 scopus 로고    scopus 로고
    • Weight loss with phentermine and topiramate extended-release in obese and overweight subjects over 56 weeks
    • [EMBASE: 71293155]
    • Kushner RF, Varghese ST. Weight loss with phentermine and topiramate extended-release in obese and overweight subjects over 56 weeks. Journal of General Internal Medicine 2013;28(Suppl1):S241. [EMBASE: 71293155]
    • (2013) Journal of General Internal Medicine , vol.28 , pp. S241
    • Kushner, R.F.1    Varghese, S.T.2
  • 19
    • 85027091013 scopus 로고    scopus 로고
    • Effects of extended-release phentermine/topiramate on weight loss and blood pressure in obese subjects with type 2 diabetes mellitus
    • EMBASE: 70888717]
    • Rossner SK, Sharma AM, Troupin B, Padwal RS. Effects of extended-release phentermine/topiramate on weight loss and blood pressure in obese subjects with type 2 diabetes mellitus. Diabetologia 2012;55(Suppl1):S285. [EMBASE: 70888717]
    • (2012) Diabetologia , vol.55 , pp. S285
    • Rossner, S.K.1    Sharma, A.M.2    Troupin, B.3    Padwal, R.S.4
  • 20
    • 84961937263 scopus 로고    scopus 로고
    • Achievement of composite of recommended goals in obese subjects with type 2 diabetes mellitus using extended-release phentermine/topiramate in a 56-week weight loss intervention
    • 3 Meeting Abstracts), EMBASE: 70832584]
    • Ryan DH, Garvey WT, Day WW. Achievement of composite of recommended goals in obese subjects with type 2 diabetes mellitus using extended-release phentermine/topiramate in a 56-week weight loss intervention. Endocrine Reviews 2012;33:(3 Meeting Abstracts). [EMBASE: 70832584]
    • (2012) Endocrine Reviews , vol.33
    • Ryan, D.H.1    Garvey, W.T.2    Day, W.W.3
  • 21
    • 85027090648 scopus 로고    scopus 로고
    • Low-dose controlled-release phentermine/topiramate (PHEN/TPM CR) results in significant weight loss and improves atherosclerotic biomarkers in overweight/obese patients with obesity-related comorbidities
    • [EMBASE: 70343842]
    • Troupin B, Hankin C S. Low-dose controlled-release phentermine/topiramate (PHEN/TPM CR) results in significant weight loss and improves atherosclerotic biomarkers in overweight/obese patients with obesity-related comorbidities. Clinical Pharmacology and Therapeutics 2011;89(Suppl1):S39. [EMBASE: 70343842]
    • (2011) Clinical Pharmacology and Therapeutics , vol.89 , pp. S39
    • Troupin, B.1    Hankin, C.S.2
  • 23
    • 17444409332 scopus 로고    scopus 로고
    • Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients
    • Faria AN, Ribeiro Filho FF, Kohlmann NE, Gouvea F Sr, Zanella MT. Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients. Diabetes, Obesity & Metabolism 2005;7(3):246-53.
    • (2005) Diabetes, Obesity & Metabolism , vol.7 , Issue.3 , pp. 246-253
    • Faria, A.N.1    Ribeiro Filho, F.F.2    Kohlmann, N.E.3    Gouvea, F.4    Zanella, M.T.5
  • 26
    • 0034710218 scopus 로고    scopus 로고
    • Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicenter trial
    • McMahon FG, Fujioka K, Singh BN, Mendel CM, Rowe E, Rolston K, et al. Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicenter trial. Archives of Internal Medicine 2000;160(14):2185-91.
    • (2000) Archives of Internal Medicine , vol.160 , Issue.14 , pp. 2185-2191
    • McMahon, F.G.1    Fujioka, K.2    Singh, B.N.3    Mendel, C.M.4    Rowe, E.5    Rolston, K.6
  • 27
    • 85047697192 scopus 로고    scopus 로고
    • Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors
    • McMahon FG, Weinstein SP, Rowe E, Ernst KR, Johnson F, Fujioka K, et al. Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors. Journal of Human Hypertension 2002;16(1):5-11.
    • (2002) Journal of Human Hypertension , vol.16 , Issue.1 , pp. 5-11
    • McMahon, F.G.1    Weinstein, S.P.2    Rowe, E.3    Ernst, K.R.4    Johnson, F.5    Fujioka, K.6
  • 28
    • 84961875334 scopus 로고    scopus 로고
    • Evaluation of the benefits and harms of non-drug weight-reducing treatment strategies in patients with essential hypertension
    • [Nutzenbewertung nichtmedikamentöser Behandlungsstrategien bei Patienten mit Bluthochdruck: A-Gewichtsreduktion].. Köln: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)
    • Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG). Evaluation of the benefits and harms of non-drug weight-reducing treatment strategies in patients with essential hypertension [Nutzenbewertung nichtmedikamentöser Behandlungsstrategien bei Patienten mit Bluthochdruck: A-Gewichtsreduktion]. http://iqwig.de/download/A05-21A_Abschlussbericht_Gewichtsreduktion_bei_Bluthochdruck_neu.pdf. Köln: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG), 2006:19-119.
    • (2006) , pp. 19-119
  • 29
    • 0034812479 scopus 로고    scopus 로고
    • Principles for enhanced recruitment of subjects in a large clinical trial. the XENDOS (XENical in the prevention of Diabetes in Obese Subjects) study experience
    • Torgerson JS, Arlinger K, Kappi M, Sjostrom L. Principles for enhanced recruitment of subjects in a large clinical trial. the XENDOS (XENical in the prevention of Diabetes in Obese Subjects) study experience. Controlled Clinical Trials 2001;22(5):515-25.
    • (2001) Controlled Clinical Trials , vol.22 , Issue.5 , pp. 515-525
    • Torgerson, J.S.1    Arlinger, K.2    Kappi, M.3    Sjostrom, L.4
  • 30
    • 1042303480 scopus 로고    scopus 로고
    • XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
    • Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004;27(1):155-61.
    • (2004) Diabetes Care , vol.27 , Issue.1 , pp. 155-161
    • Torgerson, J.S.1    Hauptman, J.2    Boldrin, M.N.3    Sjostrom, L.4
  • 31
    • 0033082197 scopus 로고    scopus 로고
    • Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine
    • PUBMED: 10230747]
    • Apfelbaum M, Vague P, Ziegler O, Hanotin C, Thomas F, Leutenegger E. Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine. American Journal of Medicine 1999;106(2):179-84. [PUBMED: 10230747]
    • (1999) American Journal of Medicine , vol.106 , Issue.2 , pp. 179-184
    • Apfelbaum, M.1    Vague, P.2    Ziegler, O.3    Hanotin, C.4    Thomas, F.5    Leutenegger, E.6
  • 33
    • 84961921958 scopus 로고    scopus 로고
    • A randomised, placebo-controlled trial of liraglutide as adjunct to basal insulin analogues in subjects with Type 2 diabetes (LIRA-ADD2BASAL)
    • EMBASE: 71821007]
    • Bain SC, Ahmann A, Rodbard H, W.Rosenstock J, Lahtela J, De Loredo L, et al. A randomised, placebo-controlled trial of liraglutide as adjunct to basal insulin analogues in subjects with Type 2 diabetes (LIRA-ADD2BASAL). Diabetic Medicine 2015;32(Suppl1):71. [EMBASE: 71821007]
    • (2015) Diabetic Medicine , vol.32 , pp. 71
    • Bain, S.C.1    Ahmann, A.2    Rodbard, H.3    W.Rosenstock, J.4    Lahtela, J.5    De Loredo, L.6
  • 35
    • 77649182432 scopus 로고    scopus 로고
    • Lorcaserin reduces body weight in obese and overweight subjects: Behavioral modification and lorcaserin for overweight and obesity management, the BLOOM trial
    • EMBASE: 70134408]
    • Smith SR, Weissman NJ, Stubbe S, Anderson CM, Shanahan WR. Lorcaserin reduces body weight in obese and overweight subjects: Behavioral modification and lorcaserin for overweight and obesity management, the BLOOM trial. Diabetes 2009;58:LB24. [EMBASE: 70134408]
    • (2009) Diabetes , vol.58 , pp. LB24
    • Smith, S.R.1    Weissman, N.J.2    Stubbe, S.3    Anderson, C.M.4    Shanahan, W.R.5
  • 36
    • 84894907308 scopus 로고    scopus 로고
    • Lorcaserin, a selective 5-HT2C agonist, evaluated as a weight loss agent in obese and overweight patients with type 2 diabetes treated with sulfonylureas or metformin
    • [EMBASE: 70629658]
    • Fidler MC, Shazer R, Sanchez, M, Stubbe S, Anderson CM, Shanahan WR. Lorcaserin, a selective 5-HT2C agonist, evaluated as a weight loss agent in obese and overweight patients with type 2 diabetes treated with sulfonylureas or metformin. Diabetes 2011; Vol. 60:A515. [EMBASE: 70629658]
    • (2011) Diabetes , vol.60 , pp. A515
    • Fidler, M.C.1    Shazer, R.2    Sanchez, M.3    Stubbe, S.4    Anderson, C.M.5    Shanahan, W.R.6
  • 37
    • 85027091197 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of lorcaserin for weight loss in patients with type 2 diabetes
    • [EMBASE: 70629629]
    • O'Neil PM, Fidler MC, Sanchez, M, Weissman NJ, Smith SR, Anderson CM, et al. Randomized, placebo-controlled trial of lorcaserin for weight loss in patients with type 2 diabetes. Diabetes 2011; Vol. 60:A507. [EMBASE: 70629629]
    • (2011) Diabetes , vol.60 , pp. A507
    • O'Neil, P.M.1    Fidler, M.C.2    Sanchez, M.3    Weissman, N.J.4    Smith, S.R.5    Anderson, C.M.6
  • 38
    • 84862869642 scopus 로고    scopus 로고
    • Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study
    • [PUBMED: 22421927]
    • O'Neil PM, Smith SR, Weissman NJ, Fidler MC, Sanchez M, Zhang J, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity 2012; Vol. 20, issue 7:1426-36. [PUBMED: 22421927]
    • (2012) Obesity , vol.20 , Issue.7 , pp. 1426-1436
    • O'Neil, P.M.1    Smith, S.R.2    Weissman, N.J.3    Fidler, M.C.4    Sanchez, M.5    Zhang, J.6
  • 40
    • 0036735197 scopus 로고    scopus 로고
    • Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK Multimorbidity Study
    • Broom I, Wilding J, Stott P, Myers N, UK Multimorbidity Study Group. Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK Multimorbidity Study. International Journal of Clinical Practice 2002;56(7):494-9.
    • (2002) International Journal of Clinical Practice , vol.56 , Issue.7 , pp. 494-499
    • Broom, I.1    Wilding, J.2    Stott, P.3    Myers, N.4
  • 41
    • 85027091407 scopus 로고    scopus 로고
    • Naltrexone SR/bupropion SR and intensive behavioral modification combination increases the likelihood of achieving early and sustained weight loss and associated improvement in markers of cardiometabolic risk
    • EMBASE: 70680332]
    • O'Neil PM, Wadden TA, Foreyt JP, Clapper B, Burns C, Klassen P, et al. Naltrexone SR/bupropion SR and intensive behavioral modification combination increases the likelihood of achieving early and sustained weight loss and associated improvement in markers of cardiometabolic risk. Obesity 2011;19(Suppl1):S179-80. [EMBASE: 70680332]
    • (2011) Obesity , vol.19 , pp. S179-S180
    • O'Neil, P.M.1    Wadden, T.A.2    Foreyt, J.P.3    Clapper, B.4    Burns, C.5    Klassen, P.6
  • 42
    • 77956904326 scopus 로고    scopus 로고
    • Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
    • EMBASE: 2011434989]
    • Wadden TA, Foreyt JP, Foster GD, Hill JO, Klein S, O'Neil PM, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial. Obesity 2011;19(1):110-20. [EMBASE: 2011434989]
    • (2011) Obesity , vol.19 , Issue.1 , pp. 110-120
    • Wadden, T.A.1    Foreyt, J.P.2    Foster, G.D.3    Hill, J.O.4    Klein, S.5    O'Neil, P.M.6
  • 43
    • 84891869792 scopus 로고    scopus 로고
    • Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes
    • EMBASE: 2014021906]
    • Hollander P, Gupta AK, Plodkowski R, Greenway F, Bay H, Burns C, et al. Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes. Diabetes Care 2013;36:4022-9. [EMBASE: 2014021906]
    • (2013) Diabetes Care , vol.36 , pp. 4022-4029
    • Hollander, P.1    Gupta, A.K.2    Plodkowski, R.3    Greenway, F.4    Bay, H.5    Burns, C.6
  • 44
    • 85027091613 scopus 로고    scopus 로고
    • Weight loss and improvements in markers of metabolic risk in overweight and obese subjects completing 56 weeks of treatment with naltrexone SR/bupropion SR
    • EMBASE: 70629675]
    • Fujioka K, Billes SK, Burns C, Harris-Collazo R, Kim DD, Dunayevich E, et al. Weight loss and improvements in markers of metabolic risk in overweight and obese subjects completing 56 weeks of treatment with naltrexone SR/bupropion SR. Diabetes 2011;60:A520-1. [EMBASE: 70629675]
    • (2011) Diabetes , vol.60 , pp. A520-A521
    • Fujioka, K.1    Billes, S.K.2    Burns, C.3    Harris-Collazo, R.4    Kim, D.D.5    Dunayevich, E.6
  • 45
    • 85027090367 scopus 로고    scopus 로고
    • Completion of 56 weeks of naltrexone SR/bupropion SR combination therapy increases likelihood of achieving improvements in markers of cardiometabolic risk associated with clinically meaningful weight loss
    • EMBASE: 70680330]
    • Fujioka K, Greenway FL, Rubino D, Clapper B, Burns C, Klassen P, et al. Completion of 56 weeks of naltrexone SR/bupropion SR combination therapy increases likelihood of achieving improvements in markers of cardiometabolic risk associated with clinically meaningful weight loss. Obesity 2011;19(Suppl1):S179. [EMBASE: 70680330]
    • (2011) Obesity , vol.19 , pp. S179
    • Fujioka, K.1    Greenway, F.L.2    Rubino, D.3    Clapper, B.4    Burns, C.5    Klassen, P.6
  • 46
    • 77956057548 scopus 로고    scopus 로고
    • Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
    • PUBMED: 20673995]
    • Greenway FL, Fujioka K, Plodkowski RA, Mudaliar S, Guttadauria M, Erickson J, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet 2010;376:595-605. [PUBMED: 20673995]
    • (2010) The Lancet , vol.376 , pp. 595-605
    • Greenway, F.L.1    Fujioka, K.2    Plodkowski, R.A.3    Mudaliar, S.4    Guttadauria, M.5    Erickson, J.6
  • 47
    • 85027090374 scopus 로고    scopus 로고
    • Response to NB at week 16 is a good predictor of significant week 56 weight loss and improvements in weight-related risk factors
    • EMBASE: 70630321]
    • Plutzky J, Buse J, Chilton R, Mignon L, Burns C, Harris-Collazo R, et al. Response to NB at week 16 is a good predictor of significant week 56 weight loss and improvements in weight-related risk factors. Diabetes 2011;60:A700. [EMBASE: 70630321]
    • (2011) Diabetes , vol.60 , pp. A700
    • Plutzky, J.1    Buse, J.2    Chilton, R.3    Mignon, L.4    Burns, C.5    Harris-Collazo, R.6
  • 48
    • 84879324574 scopus 로고    scopus 로고
    • A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)
    • PUBMED: 23408728]
    • Apovian CM, Aronne L, Rubino D, Still C, Wyatt H, Burns C, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity 2013;21(5):935-43. [PUBMED: 23408728]
    • (2013) Obesity , vol.21 , Issue.5 , pp. 935-943
    • Apovian, C.M.1    Aronne, L.2    Rubino, D.3    Still, C.4    Wyatt, H.5    Burns, C.6
  • 49
    • 85027091460 scopus 로고    scopus 로고
    • Naltrexone SR/bupropion SR combination therapy improves control of eating and reduces food cravings in overweight and obese subjects
    • EMBASE: 70629625]
    • Hill JO, Wyatt H, Billes SK, Burns C, Harris-Collazo R, Dunayevich E, et al. Naltrexone SR/bupropion SR combination therapy improves control of eating and reduces food cravings in overweight and obese subjects. Diabetes 2011;60:A506. [EMBASE: 70629625]
    • (2011) Diabetes , vol.60 , pp. A506
    • Hill, J.O.1    Wyatt, H.2    Billes, S.K.3    Burns, C.4    Harris-Collazo, R.5    Dunayevich, E.6
  • 50
    • 85027090964 scopus 로고    scopus 로고
    • Naltrexone SR/bupropion SR combination therapy reduced weight and improved weight-related quality of life and physical health in overweight and obese subjects
    • EMBASE: 70629628]
    • Kolotkin RL, Still C, Maier H, Burns C, Harris-Collazo R, Dunayevich E, et al. Naltrexone SR/bupropion SR combination therapy reduced weight and improved weight-related quality of life and physical health in overweight and obese subjects. Diabetes 2011;60:A506-7. [EMBASE: 70629628]
    • (2011) Diabetes , vol.60 , pp. A506-A507
    • Kolotkin, R.L.1    Still, C.2    Maier, H.3    Burns, C.4    Harris-Collazo, R.5    Dunayevich, E.6
  • 51
    • 84908061636 scopus 로고    scopus 로고
    • Weight loss, blood pressure, pulse and circadian patterns with naltrexone sustained-release/bupropion sustained-release combination therapy for obesity
    • EMBASE: 70400194]
    • Plutzky J, Chilton R, Still C, Burns C, Kim D, Dunayevich E. Weight loss, blood pressure, pulse and circadian patterns with naltrexone sustained-release/bupropion sustained-release combination therapy for obesity. Journal of the American College of Cardiology 2011;57(14, Supplement):E517. [EMBASE: 70400194]
    • (2011) Journal of the American College of Cardiology , vol.57 , Issue.14 , pp. E517
    • Plutzky, J.1    Chilton, R.2    Still, C.3    Burns, C.4    Kim, D.5    Dunayevich, E.6
  • 52
    • 85027090359 scopus 로고    scopus 로고
    • Effects of naltrexone SR/bupropion SR on weight and obesity-related health risks in overweight/obese women from the COR-II trial
    • EMBASE: 70629619]
    • Rubino D, Apovian C, Mignon L, Burns C, Harris-Collazo R, Kim D. Effects of naltrexone SR/bupropion SR on weight and obesity-related health risks in overweight/obese women from the COR-II trial. Diabetes 2011;60:A504. [EMBASE: 70629619]
    • (2011) Diabetes , vol.60 , pp. A504
    • Rubino, D.1    Apovian, C.2    Mignon, L.3    Burns, C.4    Harris-Collazo, R.5    Kim, D.6
  • 53
    • 0033585499 scopus 로고    scopus 로고
    • Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial [see comment] [erratum appears in JAMA 1999 Apr 7;281(13):1174]
    • Davidson MH, Hauptman J, DiGirolamo M, Foreyt JP, Halsted CH, Heber D, et al. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial [see comment] [erratum appears in JAMA 1999 Apr 7;281(13):1174]. JAMA 1999;281(3):235-42.
    • (1999) JAMA , vol.281 , Issue.3 , pp. 235-242
    • Davidson, M.H.1    Hauptman, J.2    DiGirolamo, M.3    Foreyt, J.P.4    Halsted, C.H.5    Heber, D.6
  • 54
    • 77349084863 scopus 로고    scopus 로고
    • A randomized double-blind study comparing the efficacy and safety of orlistat versus placebo in obese patients with mild to moderate hypercholesterolemia
    • de Castro JJ, Dias T, Chambel P, Carvalheiro M, Correia LG, Guerreiro L, et al. A randomized double-blind study comparing the efficacy and safety of orlistat versus placebo in obese patients with mild to moderate hypercholesterolemia. Revista Portuguesa de Cardiologia 2009;28(12):1361-74.
    • (2009) Revista Portuguesa de Cardiologia , vol.28 , Issue.12 , pp. 1361-1374
    • de Castro, J.J.1    Dias, T.2    Chambel, P.3    Carvalheiro, M.4    Correia, L.G.5    Guerreiro, L.6
  • 55
    • 0038746868 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled comparison of the action of orlistat, fluvastatin, or both an anthropometric measurements, blood pressure, and lipid profile in obese patients with hypercholesterolemia prescribed a standardized diet
    • Derosa G, Mugellini A, Ciccarelli L, Fogari R. Randomized, double-blind, placebo-controlled comparison of the action of orlistat, fluvastatin, or both an anthropometric measurements, blood pressure, and lipid profile in obese patients with hypercholesterolemia prescribed a standardized diet. Clinical Therapeutics 2003;25(4):1107-22.
    • (2003) Clinical Therapeutics , vol.25 , Issue.4 , pp. 1107-1122
    • Derosa, G.1    Mugellini, A.2    Ciccarelli, L.3    Fogari, R.4
  • 56
    • 53649103175 scopus 로고    scopus 로고
    • Sibutramine effect on metabolic control of obese patients with type 2 diabetes mellitus treated with pioglitazone
    • Derosa G, D'Angelo A, Salvadeo SA, Ferrari I, Gravina A, Fogari E, et al. Sibutramine effect on metabolic control of obese patients with type 2 diabetes mellitus treated with pioglitazone. Metabolism: Clinical & Experimental 2008;57(11):1552-7.
    • (2008) Metabolism: Clinical & Experimental , vol.57 , Issue.11 , pp. 1552-1557
    • Derosa, G.1    D'Angelo, A.2    Salvadeo, S.A.3    Ferrari, I.4    Gravina, A.5    Fogari, E.6
  • 59
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Despres JP, Golay A, Sjostrom L. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. The New England Journal of Medicine 2005;353(20):2121-34.
    • (2005) The New England Journal of Medicine , vol.353 , Issue.20 , pp. 2121-2134
    • Despres, J.P.1    Golay, A.2    Sjostrom, L.3
  • 60
    • 61549116530 scopus 로고    scopus 로고
    • Effect of rimonabant on the high-triglyceride/low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial
    • Despres JP, Ross R, Boka G, Almeras N, Lemieux I. Effect of rimonabant on the high-triglyceride/low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial. Arteriosclerosis, Thrombosis, and Vascular Biology 2009;29(3):416-23.
    • (2009) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.29 , Issue.3 , pp. 416-423
    • Despres, J.P.1    Ross, R.2    Boka, G.3    Almeras, N.4    Lemieux, I.5
  • 61
    • 0034878265 scopus 로고    scopus 로고
    • Effects of sibutramine on body weight and serum lipids: A double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia
    • Dujovne CA, Zavoral JH, Rowe E, Mendel CM. Effects of sibutramine on body weight and serum lipids: A double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia. American Heart Journal 2001;142(3):489-97.
    • (2001) American Heart Journal , vol.142 , Issue.3 , pp. 489-497
    • Dujovne, C.A.1    Zavoral, J.H.2    Rowe, E.3    Mendel, C.M.4
  • 62
    • 84856246606 scopus 로고    scopus 로고
    • Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)
    • PUBMED: 22051941]
    • Allison DB, Gadde KM, Garvey WT, Peterson CA, Schwiers ML, Najarian T, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity 2012;20(2):330-42. [PUBMED: 22051941]
    • (2012) Obesity , vol.20 , Issue.2 , pp. 330-342
    • Allison, D.B.1    Gadde, K.M.2    Garvey, W.T.3    Peterson, C.A.4    Schwiers, M.L.5    Najarian, T.6
  • 63
    • 2942519185 scopus 로고    scopus 로고
    • Cholesterol lowering effect of dietary weight loss and orlistat treatment - Efficacy and limitations
    • Erdmann J, Lippl F, Klose G, Schusdziarra V. Cholesterol lowering effect of dietary weight loss and orlistat treatment - Efficacy and limitations. Alimentary Pharmacology and Therapeutics 2004;19(11):1173-9.
    • (2004) Alimentary Pharmacology and Therapeutics , vol.19 , Issue.11 , pp. 1173-1179
    • Erdmann, J.1    Lippl, F.2    Klose, G.3    Schusdziarra, V.4
  • 67
    • 0034522392 scopus 로고    scopus 로고
    • Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus
    • Fujioka K, Seaton TB, Rowe E, Jelinek CA, Raskin P, Lebovitz HE, et al. Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus. Diabetes, Obesity & Metabolism 2000;2(3):175-87.
    • (2000) Diabetes, Obesity & Metabolism , vol.2 , Issue.3 , pp. 175-187
    • Fujioka, K.1    Seaton, T.B.2    Rowe, E.3    Jelinek, C.A.4    Raskin, P.5    Lebovitz, H.E.6
  • 68
    • 84886897827 scopus 로고    scopus 로고
    • Treatment with VI-0521 (phentermine and topiramate) leads to one year durable glycaemic benefit and weight loss in subjects with type 2 diabetes
    • EMBASE: 70067664]
    • Garvey WT, Troupin B, Peterson C, Najarian T, Tam P, Day W. Treatment with VI-0521 (phentermine and topiramate) leads to one year durable glycaemic benefit and weight loss in subjects with type 2 diabetes. Diabetologia 2009;52(S1):S77. [EMBASE: 70067664]
    • (2009) Diabetologia , vol.52 , pp. S77
    • Garvey, W.T.1    Troupin, B.2    Peterson, C.3    Najarian, T.4    Tam, P.5    Day, W.6
  • 69
    • 84962336361 scopus 로고    scopus 로고
    • One-year treatment with VI-0521 in type 2 diabetes demonstrates continued glycemic improvement and weight loss
    • EMBASE: 70136156]
    • Garvey WT, Troupin B, Tam P, Najarian T, Peterson C, Day WW. One-year treatment with VI-0521 in type 2 diabetes demonstrates continued glycemic improvement and weight loss. Diabetes 2009;58(Suppl. 1):A95. [EMBASE: 70136156]
    • (2009) Diabetes , vol.58 , pp. A95
    • Garvey, W.T.1    Troupin, B.2    Tam, P.3    Najarian, T.4    Peterson, C.5    Day, W.W.6
  • 70
    • 70049094140 scopus 로고    scopus 로고
    • Efficacy and safety of a short-time orlistat treatment in obese subjects. [Italian]
    • Efficacia e sicurezza di impiego di un trattamento a breve termine con orlistat in soggetti obesi]
    • Gentile S, Guarina G, Padovano B, Buonocunto F, Gruppo Campano Obesita. Efficacy and safety of a short-time orlistat treatment in obese subjects. [Italian] [Efficacia e sicurezza di impiego di un trattamento a breve termine con orlistat in soggetti obesi]. Annali Italiani di Medicina Interna 2005;20(2):90-6.
    • (2005) Annali Italiani di Medicina Interna , vol.20 , Issue.2 , pp. 90-96
    • Gentile, S.1    Guarina, G.2    Padovano, B.3    Buonocunto, F.4
  • 71
    • 3442876113 scopus 로고    scopus 로고
    • Add-on sibutramine for olanzapine-induced weight gain
    • Ginsberg DL. Add-on sibutramine for olanzapine-induced weight gain. Primary Psychiatry 2004;11(7):24.
    • (2004) Primary Psychiatry , vol.11 , Issue.7 , pp. 24
    • Ginsberg, D.L.1
  • 74
    • 0037406461 scopus 로고    scopus 로고
    • Latin-American trial of orlistat for weight loss and improvement in glycaemic profile in obese diabetic patients
    • Halpern A, Mancini MC, Suplicy H, Zanella MT, Repetto G, Gross J, et al. Latin-American trial of orlistat for weight loss and improvement in glycaemic profile in obese diabetic patients. Diabetes, Obesity & Metabolism 2003;5(3):180-8.
    • (2003) Diabetes, Obesity & Metabolism , vol.5 , Issue.3 , pp. 180-188
    • Halpern, A.1    Mancini, M.C.2    Suplicy, H.3    Zanella, M.T.4    Repetto, G.5    Gross, J.6
  • 78
    • 33846815271 scopus 로고    scopus 로고
    • Endocannabinoid blockade for improving glycemic control and lipids in patients with type 2 diabetes mellitus
    • Hollander P. Endocannabinoid blockade for improving glycemic control and lipids in patients with type 2 diabetes mellitus. American Journal of Medicine 2007;120(2 Suppl 1):S18-28.
    • (2007) American Journal of Medicine , vol.120 , Issue.2 , pp. S18-S28
    • Hollander, P.1
  • 79
    • 22644441545 scopus 로고    scopus 로고
    • Sibutramine improves insulin sensitivity without alteration of serum adiponectin in obese subjects with Type 2 diabetes
    • Hung YJ, Chen YC, Pei D, Kuo SW, Hsieh CH, Wu LY, et al. Sibutramine improves insulin sensitivity without alteration of serum adiponectin in obese subjects with Type 2 diabetes. Diabetic Medicine 2005;22(8):1024-30.
    • (2005) Diabetic Medicine , vol.22 , Issue.8 , pp. 1024-1030
    • Hung, Y.J.1    Chen, Y.C.2    Pei, D.3    Kuo, S.W.4    Hsieh, C.H.5    Wu, L.Y.6
  • 82
    • 0034516930 scopus 로고    scopus 로고
    • Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance [see comment]
    • James WP, Astrup A, Finer N, Hilsted J, Kopelman P, Rossner S, et al. Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance [see comment]. The Lancet 2000;356(9248):2119-25.
    • (2000) The Lancet , vol.356 , Issue.9248 , pp. 2119-2125
    • James, W.P.1    Astrup, A.2    Finer, N.3    Hilsted, J.4    Kopelman, P.5    Rossner, S.6
  • 83
    • 78650195922 scopus 로고    scopus 로고
    • Trial of lorcaserin for weight management
    • PUBMED: 21158670]
    • Jia J, Xiong L, Chen S. Trial of lorcaserin for weight management. The New England Journal of Medicine 2010;363(25):2468-9. [PUBMED: 21158670]
    • (2010) The New England Journal of Medicine , vol.363 , Issue.25 , pp. 2468-2469
    • Jia, J.1    Xiong, L.2    Chen, S.3
  • 84
    • 84886893936 scopus 로고    scopus 로고
    • Effects of phentermine and extended-release topiramate alone and in combination on cardiovascular risk factors
    • EMBASE: 70888718]
    • Jordan J, Astrup AV, Day WW. Effects of phentermine and extended-release topiramate alone and in combination on cardiovascular risk factors. Diabetologia 2012;55:S285. [EMBASE: 70888718]
    • (2012) Diabetologia , vol.55 , pp. S285
    • Jordan, J.1    Astrup, A.V.2    Day, W.W.3
  • 86
    • 0036598137 scopus 로고    scopus 로고
    • Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial [erratum appears in Diabetes Care 2003 Mar;26(3):971]
    • Kelley DE, Bray GA, Pi-Sunyer FX, Klein S, Hill J, Miles J, et al. Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial [erratum appears in Diabetes Care 2003 Mar;26(3):971]. Diabetes Care 2002;25(6):1033-41.
    • (2002) Diabetes Care , vol.25 , Issue.6 , pp. 1033-1041
    • Kelley, D.E.1    Bray, G.A.2    Pi-Sunyer, F.X.3    Klein, S.4    Hill, J.5    Miles, J.6
  • 87
    • 84910606443 scopus 로고    scopus 로고
    • Weight loss achieved with medication can delay onset of type 2 diabetes in at-risk individuals
    • [EMBASE: 2014910274]
    • Lewis K. Weight loss achieved with medication can delay onset of type 2 diabetes in at-risk individuals. Journal of Clinical Outcomes Management 2014;21:393-5. [EMBASE: 2014910274]
    • (2014) Journal of Clinical Outcomes Management , vol.21 , pp. 393-395
    • Lewis, K.1
  • 88
    • 0033823438 scopus 로고    scopus 로고
    • The effect of orlistat on body weight and coronary heart disease risk profile in obese patients: the Swedish Multimorbidity Study [see comment]
    • Lindgarde F. The effect of orlistat on body weight and coronary heart disease risk profile in obese patients: the Swedish Multimorbidity Study [see comment]. Journal of Internal Medicine 2000;248(3):245-54.
    • (2000) Journal of Internal Medicine , vol.248 , Issue.3 , pp. 245-254
    • Lindgarde, F.1
  • 89
    • 0035185428 scopus 로고    scopus 로고
    • Orlistat with diet was effective and safe for weight loss and coronary risk reduction in obesity
    • Lindgarde F. Orlistat with diet was effective and safe for weight loss and coronary risk reduction in obesity. Evidence-Based Medicine 2001;6(2):54.
    • (2001) Evidence-Based Medicine , vol.6 , Issue.2 , pp. 54
    • Lindgarde, F.1
  • 90
    • 70049093618 scopus 로고    scopus 로고
    • Effect of orlistat on coronary heart disease risk in obese patients with hypertension and/or hyperlipidemia
    • Lindgarde F. Effect of orlistat on coronary heart disease risk in obese patients with hypertension and/or hyperlipidemia. American Heart Journal 2001;141(1):171.
    • (2001) American Heart Journal , vol.141 , Issue.1 , pp. 171
    • Lindgarde, F.1
  • 91
    • 66349096555 scopus 로고    scopus 로고
    • Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects
    • Madsen EL, Bruun JM, Skogstrand K, Hougaard DM, Christiansen T, Richelsen B. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. Metabolism 2009;58(7):946-53.
    • (2009) Metabolism , vol.58 , Issue.7 , pp. 946-953
    • Madsen, E.L.1    Bruun, J.M.2    Skogstrand, K.3    Hougaard, D.M.4    Christiansen, T.5    Richelsen, B.6
  • 92
    • 0038510366 scopus 로고    scopus 로고
    • A randomized trial of sibutramine in the management of obese type 2 diabetic patients treated with metformin
    • McNulty SJ, Ur E, Williams G, Multicenter Sibutramine Study Group. A randomized trial of sibutramine in the management of obese type 2 diabetic patients treated with metformin. Diabetes Care 2003;26(1):125-31.
    • (2003) Diabetes Care , vol.26 , Issue.1 , pp. 125-131
    • McNulty, S.J.1    Ur, E.2    Williams, G.3
  • 93
    • 0036634125 scopus 로고    scopus 로고
    • Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin [erratum appears in Diabetes Care 2002 Sep;25(9):1671]
    • Miles JM, Leiter L, Hollander P, Wadden T, Anderson JW, Doyle M, et al. Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin [erratum appears in Diabetes Care 2002 Sep;25(9):1671]. Diabetes Care 2002;25(7):1123-8.
    • (2002) Diabetes Care , vol.25 , Issue.7 , pp. 1123-1128
    • Miles, J.M.1    Leiter, L.2    Hollander, P.3    Wadden, T.4    Anderson, J.W.5    Doyle, M.6
  • 94
    • 84961934562 scopus 로고    scopus 로고
    • Liraglutide once daily reduces the prevalence of prediabetes and metabolic syndrome in obese non-diabetic adults: A 2-year randomized trial
    • EMBASE: 71774529]
    • Niskanen L, Astrup A, Hakim MA, Carraro R, Finer N, Hartvig H, et al. Liraglutide once daily reduces the prevalence of prediabetes and metabolic syndrome in obese non-diabetic adults: A 2-year randomized trial. Obesity 2010;18:S56. [EMBASE: 71774529]
    • (2010) Obesity , vol.18 , pp. S56
    • Niskanen, L.1    Astrup, A.2    Hakim, M.A.3    Carraro, R.4    Finer, N.5    Hartvig, H.6
  • 95
    • 41649090426 scopus 로고    scopus 로고
    • Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial
    • Nissen SE, Nicholls SJ, Wolski K, Rodes-Cabau J, Cannon CP, Deanfield JE, et al. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial. JAMA 2008;299(13):1547-60.
    • (2008) JAMA , vol.299 , Issue.13 , pp. 1547-1560
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3    Rodes-Cabau, J.4    Cannon, C.P.5    Deanfield, J.E.6
  • 96
    • 80955180984 scopus 로고    scopus 로고
    • Effect of rimonabant on carotid intima-media thickness (CIMT) progression in patients with abdominal obesity and metabolic syndrome: the AUDITOR Trial
    • O'Leary DH, Reuwer AQ, Nissen SE, Despres JP, Deanfield JE, Brown MW, et al. Effect of rimonabant on carotid intima-media thickness (CIMT) progression in patients with abdominal obesity and metabolic syndrome: the AUDITOR Trial. Heart 2011;97(14):1143-50.
    • (2011) Heart , vol.97 , Issue.14 , pp. 1143-1150
    • O'Leary, D.H.1    Reuwer, A.Q.2    Nissen, S.E.3    Despres, J.P.4    Deanfield, J.E.5    Brown, M.W.6
  • 97
    • 4143131023 scopus 로고    scopus 로고
    • Orlistat as an adjunct therapy in type 2 obese diabetic patients treated with sulphonylurea: a Bangladesh experience
    • Pathan MF, Latif ZA, Nazneen NE, Mili SU. Orlistat as an adjunct therapy in type 2 obese diabetic patients treated with sulphonylurea: a Bangladesh experience. Bangladesh Medical Research Council Bulletin 2004;30(1):1-8.
    • (2004) Bangladesh Medical Research Council Bulletin , vol.30 , Issue.1 , pp. 1-8
    • Pathan, M.F.1    Latif, Z.A.2    Nazneen, N.E.3    Mili, S.U.4
  • 98
    • 36849013414 scopus 로고    scopus 로고
    • Obesity-related hypertension
    • Patschan S, Scholze J. Obesity-related hypertension. Cardiology Review 2007;24(12):32-5.
    • (2007) Cardiology Review , vol.24 , Issue.12 , pp. 32-35
    • Patschan, S.1    Scholze, J.2
  • 99
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial [see comment] [erratum appears in JAMA 2006 Mar 15;295(11):1252]
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J, RIO-North America Study Group. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial [see comment] [erratum appears in JAMA 2006 Mar 15;295(11):1252]. JAMA 2006;295(7):761-75.
    • (2006) JAMA , vol.295 , Issue.7 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3    Devin, J.4    Rosenstock, J.5
  • 100
    • 0035313327 scopus 로고    scopus 로고
    • Effect of orlistat-assisted weight loss in decreasing coronary heart disease risk in patients with syndrome X
    • Reaven G, Segal K, Hauptman J, Boldrin M, Lucas C. Effect of orlistat-assisted weight loss in decreasing coronary heart disease risk in patients with syndrome X. American Journal of Cardiology 2001;87(7):827-31.
    • (2001) American Journal of Cardiology , vol.87 , Issue.7 , pp. 827-831
    • Reaven, G.1    Segal, K.2    Hauptman, J.3    Boldrin, M.4    Lucas, C.5
  • 101
    • 0033629936 scopus 로고    scopus 로고
    • Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity. European Orlistat Obesity Study Group
    • Rossner S, Sjostrom L, Noack R, Meinders AE, Noseda G. Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity. European Orlistat Obesity Study Group. Obesity Research 2000;8(1):49-61.
    • (2000) Obesity Research , vol.8 , Issue.1 , pp. 49-61
    • Rossner, S.1    Sjostrom, L.2    Noack, R.3    Meinders, A.E.4    Noseda, G.5
  • 102
    • 0035843678 scopus 로고    scopus 로고
    • Sibutramine - antidepressive agent tested against obesity. [Swedish]
    • [Sibutramin - antidepressivt läkemedel prövat mot fetma]. ;():-
    • Rossner S. Sibutramine - antidepressive agent tested against obesity. [Swedish] [Sibutramin - antidepressivt läkemedel prövat mot fetma]. Lakartidningen 2001;98(15):1802-3.
    • (2001) Lakartidningen , vol.98 , Issue.15 , pp. 1802-1803
    • Rossner, S.1
  • 103
    • 0037407279 scopus 로고    scopus 로고
    • Decreasing levels of tumour necrosis factor alpha and interleukin 6 during lowering of body mass index with orlistat or placebo in obese subjects with cardiovascular risk factors
    • Samuelsson L, Gottsater A, Lindgarde F. Decreasing levels of tumour necrosis factor alpha and interleukin 6 during lowering of body mass index with orlistat or placebo in obese subjects with cardiovascular risk factors. Diabetes, Obesity and Metabolism 2003;5(3):195-201.
    • (2003) Diabetes, Obesity and Metabolism , vol.5 , Issue.3 , pp. 195-201
    • Samuelsson, L.1    Gottsater, A.2    Lindgarde, F.3
  • 104
    • 84930187498 scopus 로고    scopus 로고
    • Effect of liraglutide 3.0/1.8 mg on body weight and cardiometabolic risk factors in overweight/obese adults with type 2 diabetes: SCALE diabetes randomised, double-blind, 56-week trial
    • EMBASE: 71594831]
    • Bode B, DeFronzo R, Bergenstal R, Kushner R, Lewin A, Skjoth T V, et al. Effect of liraglutide 3.0/1.8 mg on body weight and cardiometabolic risk factors in overweight/obese adults with type 2 diabetes: SCALE diabetes randomised, double-blind, 56-week trial. Diabetologia 2014;57(Suppl1):S83. [EMBASE: 71594831]
    • (2014) Diabetologia , vol.57 , pp. S83
    • Bode, B.1    DeFronzo, R.2    Bergenstal, R.3    Kushner, R.4    Lewin, A.5    Skjoth, T.V.6
  • 105
    • 84961969489 scopus 로고    scopus 로고
    • Liraglutide 3.0mg results in significant weight loss and improvements in cardiometabolic risk factors compared with liraglutide 1.8mg or placebo: A randomised, double-blind, 56 week trial in overweight/obese adults with Type 2 diabetes (SCALE diabetes)
    • EMBASE: 71821008]
    • Davies MJ, DeFronzo RA, Bergenstal RM, Bode BW, Kushner R, Noctor M, et al. Liraglutide 3.0mg results in significant weight loss and improvements in cardiometabolic risk factors compared with liraglutide 1.8mg or placebo: A randomised, double-blind, 56 week trial in overweight/obese adults with Type 2 diabetes (SCALE diabetes). Diabetic Medicine 2015;32:72. [EMBASE: 71821008]
    • (2015) Diabetic Medicine , vol.32 , pp. 72
    • Davies, M.J.1    DeFronzo, R.A.2    Bergenstal, R.M.3    Bode, B.W.4    Kushner, R.5    Noctor, M.6
  • 106
    • 84961921914 scopus 로고    scopus 로고
    • Diet-induced weight loss and subsequent addition of liraglutide 3.0 mg reduces impaired fasting glucose in overweight/obese adults in the scaleTM maintenance 56-week randomised trial
    • EMBASE: 71034943]
    • Hollander P, Aronne L, Klein S, Niswender K, Jensen CB, Woo V, et al. Diet-induced weight loss and subsequent addition of liraglutide 3.0 mg reduces impaired fasting glucose in overweight/obese adults in the scaleTM maintenance 56-week randomised trial. Journal of Diabetes 2013;5:124. [EMBASE: 71034943]
    • (2013) Journal of Diabetes , vol.5 , pp. 124
    • Hollander, P.1    Aronne, L.2    Klein, S.3    Niswender, K.4    Jensen, C.B.5    Woo, V.6
  • 107
    • 84961937287 scopus 로고    scopus 로고
    • Efficacy and safety of liraglutide 3.0 mg for weight management in overweight/obese adults: The SCALE obesity and prediabetes trial
    • EMBASE: 71595554]
    • Fujioka K, Wilding JPH, Astrup A, Greenway F, Halpern A, Krempf M, et al. Efficacy and safety of liraglutide 3.0 mg for weight management in overweight/obese adults: The SCALE obesity and prediabetes trial. Diabetologia 2014;57(Suppl1):S368-9. [EMBASE: 71595554]
    • (2014) Diabetologia , vol.57 , pp. S368-S369
    • Fujioka, K.1    Wilding, J.P.H.2    Astrup, A.3    Greenway, F.4    Halpern, A.5    Krempf, M.6
  • 108
    • 84961921912 scopus 로고    scopus 로고
    • Liraglutide 3.0 mg reduces body weight and improves cardiometabolic risk factors in overweight/obese adults: The SCALE obesity and prediabetes randomised trial
    • EMBASE: 71595553]
    • Krempf M, Astrup A, Le Roux C, Fujioka K, Greenway F, Halpern A, et al. Liraglutide 3.0 mg reduces body weight and improves cardiometabolic risk factors in overweight/obese adults: The SCALE obesity and prediabetes randomised trial. Diabetologia 2014;57(Suppl1):S368. [EMBASE: 71595553]
    • (2014) Diabetologia , vol.57 , pp. S368
    • Krempf, M.1    Astrup, A.2    Le Roux, C.3    Fujioka, K.4    Greenway, F.5    Halpern, A.6
  • 109
    • 84961873383 scopus 로고    scopus 로고
    • Efficacy and safety of liraglutide 3.0mg for weight management in overweight and obese adults: The SCALE obesity and prediabetes, a randomised, double-blind and placebo-controlled trial
    • EMBASE: 71741424]
    • Proietto J, Le Roux CW, Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, et al. Efficacy and safety of liraglutide 3.0mg for weight management in overweight and obese adults: The SCALE obesity and prediabetes, a randomised, double-blind and placebo-controlled trial. Obesity Research and Clinical Practice 2014;8:117. [EMBASE: 71741424]
    • (2014) Obesity Research and Clinical Practice , vol.8 , pp. 117
    • Proietto, J.1    Le Roux, C.W.2    Pi-Sunyer, X.3    Astrup, A.4    Fujioka, K.5    Greenway, F.6
  • 110
    • 84930178453 scopus 로고    scopus 로고
    • Efficacy and safety of liraglutide 3.0 mg for weight management in overweight and obese adults: The scaleTM obesity and prediabetes, a randomised, double-blind and placebo-controlled trial
    • EMBASE: 71497901]
    • Wilding J, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, et al. Efficacy and safety of liraglutide 3.0 mg for weight management in overweight and obese adults: The scaleTM obesity and prediabetes, a randomised, double-blind and placebo-controlled trial. Obesity Facts 2014;7:15. [EMBASE: 71497901]
    • (2014) Obesity Facts , vol.7 , pp. 15
    • Wilding, J.1    Astrup, A.2    Fujioka, K.3    Greenway, F.4    Halpern, A.5    Krempf, M.6
  • 111
    • 84961969498 scopus 로고    scopus 로고
    • Safety and tolerability of liraglutide 3.0mg following 56 weeks of randomised treatment in overweight and obese adults: SCALE obesity and pre-diabetes trial
    • EMBASE: 71821004]
    • Wilding J, Lau D, Astrup A, Fujioka K, Greenway F, Krempf M, et al. Safety and tolerability of liraglutide 3.0mg following 56 weeks of randomised treatment in overweight and obese adults: SCALE obesity and pre-diabetes trial. Diabetic Medicine 2015;32:70. [EMBASE: 71821004]
    • (2015) Diabetic Medicine , vol.32 , pp. 70
    • Wilding, J.1    Lau, D.2    Astrup, A.3    Fujioka, K.4    Greenway, F.5    Krempf, M.6
  • 112
    • 84961864742 scopus 로고    scopus 로고
    • Liraglutide 3.0mg improves body weight and cardiometabolic risk factors in overweight or obese adults without diabetes: The SCALE Obesity and Prediabetes randomised, double-blind, placebo-controlled 56-week trial
    • EMBASE: 71742425]
    • Wittert G, Le Roux CW, Astrup A, Fujioka K, Greenway F, Halpern A, et al. Liraglutide 3.0mg improves body weight and cardiometabolic risk factors in overweight or obese adults without diabetes: The SCALE Obesity and Prediabetes randomised, double-blind, placebo-controlled 56-week trial. Obesity Research and Clinical Practice 2014;8:118. [EMBASE: 71742425]
    • (2014) Obesity Research and Clinical Practice , vol.8 , pp. 118
    • Wittert, G.1    Le Roux, C.W.2    Astrup, A.3    Fujioka, K.4    Greenway, F.5    Halpern, A.6
  • 113
    • 84961864746 scopus 로고    scopus 로고
    • Liraglutide 3.0 mg reduces severity of obstructive sleep apnoea and body weight in obese individuals with moderate or severe disease: Scale sleep apnoea trial
    • EMBASE: 71688686]
    • Collier A, Blackman A, Foster G, Zammit G, Rosenberg R, Wadden T, et al. Liraglutide 3.0 mg reduces severity of obstructive sleep apnoea and body weight in obese individuals with moderate or severe disease: Scale sleep apnoea trial. Thorax 2014;69:A16-7. [EMBASE: 71688686]
    • (2014) Thorax , vol.69 , pp. A16-A17
    • Collier, A.1    Blackman, A.2    Foster, G.3    Zammit, G.4    Rosenberg, R.5    Wadden, T.6
  • 114
    • 0036943785 scopus 로고    scopus 로고
    • New antiobesity agents in type 2 diabetes: Overview of clinical trials with sibutramine and orlistat
    • Scheen AJ, Ernest P. New antiobesity agents in type 2 diabetes: Overview of clinical trials with sibutramine and orlistat. Diabetes and Metabolism 2002;28(6 I):437-45.
    • (2002) Diabetes and Metabolism , vol.28 , Issue.6 , pp. 437-445
    • Scheen, A.J.1    Ernest, P.2
  • 115
    • 85027091216 scopus 로고    scopus 로고
    • Effects on mortality and morbidity in overweight/obese subjects: The sibutramine cardiovascular outcomes (SCOUT) trial
    • Conference: American College of Cardiology's 59th Annual Scientific Session and i2 Summit: Innovation in Intervention Atlanta, GA United States. Conference Start: 20100314 Conference End: 20100316. Conference Publication: var.pagings)
    • James P, Caterson I, Coutinho W, Finer N, Van Gaal L, Maggioni A, et al. Effects on mortality and morbidity in overweight/obese subjects: The sibutramine cardiovascular outcomes (SCOUT) trial. Journal of the American College of Cardiology 2010;Conference: American College of Cardiology's 59th Annual Scientific Session and i2 Summit: Innovation in Intervention Atlanta, GA United States. Conference Start: 20100314 Conference End: 20100316. Conference Publication:(var.pagings). 55 (10 SUPPL 1):A141.E1326.
    • (2010) Journal of the American College of Cardiology , vol.55 , Issue.10 , pp. A141E1326
    • James, P.1    Caterson, I.2    Coutinho, W.3    Finer, N.4    Van Gaal, L.5    Maggioni, A.6
  • 117
    • 59449102203 scopus 로고    scopus 로고
    • Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial
    • Maggioni AP, Caterson I, Coutinho W, Finer N, Gaal LV, Sharma AM, et al. Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial. Journal of Cardiovascular Pharmacology 2008;52(5):393-402.
    • (2008) Journal of Cardiovascular Pharmacology , vol.52 , Issue.5 , pp. 393-402
    • Maggioni, A.P.1    Caterson, I.2    Coutinho, W.3    Finer, N.4    Gaal, L.V.5    Sharma, A.M.6
  • 118
    • 84961882258 scopus 로고    scopus 로고
    • Changes in body weight and blood pressure: Paradoxical outcome events in overweight and obese subjects with cardiovascular disease
    • EMBASE: 71516191]
    • Seimon R, Espinoza D, Ivers L, Gebski V, Finer N, Legler U, et al. Changes in body weight and blood pressure: Paradoxical outcome events in overweight and obese subjects with cardiovascular disease. Obesity Reviews 2014;15:173. [EMBASE: 71516191]
    • (2014) Obesity Reviews , vol.15 , pp. 173
    • Seimon, R.1    Espinoza, D.2    Ivers, L.3    Gebski, V.4    Finer, N.5    Legler, U.6
  • 119
    • 84924980263 scopus 로고    scopus 로고
    • Changes in body weight and blood pressure: paradoxical outcome events in overweight and obese subjects with cardiovascular disease
    • PUBMED: 24406481]
    • Seimon RV, Espinoza D, Ivers L, Gebski V, Finer N, Legler UF, et al. Changes in body weight and blood pressure: paradoxical outcome events in overweight and obese subjects with cardiovascular disease. International Journal of Obesity 2014;38:1165-71. [PUBMED: 24406481]
    • (2014) International Journal of Obesity , vol.38 , pp. 1165-1171
    • Seimon, R.V.1    Espinoza, D.2    Ivers, L.3    Gebski, V.4    Finer, N.5    Legler, U.F.6
  • 120
    • 84871843784 scopus 로고    scopus 로고
    • Significant weight loss with controlled-release phentermine/topiramate (PHEN/TPM CR) is associated with significant reductions in use of concomitant medications for cardiometabolic diseases over 108 weeks
    • EMBASE: 70680319]
    • Garvey WT, Najarian T, Peterson CA. Significant weight loss with controlled-release phentermine/topiramate (PHEN/TPM CR) is associated with significant reductions in use of concomitant medications for cardiometabolic diseases over 108 weeks. Obesity 2011;19:S176. [EMBASE: 70680319]
    • (2011) Obesity , vol.19 , pp. S176
    • Garvey, W.T.1    Najarian, T.2    Peterson, C.A.3
  • 121
    • 84897883613 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes in subjects with prediabetes and metabolic syndrome treated with phentermine and topiramate extended release
    • PUBMED: 24103901]
    • Garvey WT, Ryan DH, Henry R, Bohannon NJ, Toplak H, Schwiers M, et al. Prevention of type 2 diabetes in subjects with prediabetes and metabolic syndrome treated with phentermine and topiramate extended release. Diabetes Care 2014;37:912-21. [PUBMED: 24103901]
    • (2014) Diabetes Care , vol.37 , pp. 912-921
    • Garvey, W.T.1    Ryan, D.H.2    Henry, R.3    Bohannon, N.J.4    Toplak, H.5    Schwiers, M.6
  • 122
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
    • EMBASE: 2012064424]
    • Garvey WT, Ryan DH, Look M, Gadde KM, Allison DB, Peterson CA, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study. American Journal of Clinical Nutrition 2012;95:297-308. [EMBASE: 2012064424]
    • (2012) American Journal of Clinical Nutrition , vol.95 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3    Gadde, K.M.4    Allison, D.B.5    Peterson, C.A.6
  • 123
    • 84871845724 scopus 로고    scopus 로고
    • Weight loss (WL) with low-dose, controlled-release phentermine/topiramate (PHEN/TPM CR) correlates with improvements in liver function in overweight/obese adults with elevated alanine aminotransferase (ALT)
    • EMBASE: 70680321]
    • Klein S, Najarian T, Troupin B, Day WW. Weight loss (WL) with low-dose, controlled-release phentermine/topiramate (PHEN/TPM CR) correlates with improvements in liver function in overweight/obese adults with elevated alanine aminotransferase (ALT). Obesity 2011;19:S177. [EMBASE: 70680321]
    • (2011) Obesity , vol.19 , pp. S177
    • Klein, S.1    Najarian, T.2    Troupin, B.3    Day, W.W.4
  • 124
    • 85027090616 scopus 로고    scopus 로고
    • Long-term weight loss with controlled-release phentermine/topiramate reverses metabolic syndrome and improves associated traits
    • EMBASE: 70563050]
    • Toplak H, Rossner S, Garvey WT, Troupin B, Bowden CH. Long-term weight loss with controlled-release phentermine/topiramate reverses metabolic syndrome and improves associated traits. Diabetologia 2011;54:S370. [EMBASE: 70563050]
    • (2011) Diabetologia , vol.54 , pp. S370
    • Toplak, H.1    Rossner, S.2    Garvey, W.T.3    Troupin, B.4    Bowden, C.H.5
  • 125
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group [see comment]
    • Sjostrom L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HP, et al. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group [see comment]. The Lancet 1998;352(9123):167-72.
    • (1998) The Lancet , vol.352 , Issue.9123 , pp. 167-172
    • Sjostrom, L.1    Rissanen, A.2    Andersen, T.3    Boldrin, M.4    Golay, A.5    Koppeschaar, H.P.6
  • 126
    • 0035316759 scopus 로고    scopus 로고
    • Influence of sibutramine on energy expenditure in African American women
    • PUBMED: 11331428]
    • Starling RD, Liu X, Sullivan DH. Influence of sibutramine on energy expenditure in African American women. Obesity Research 2001;9(4):251-6. [PUBMED: 11331428]
    • (2001) Obesity Research , vol.9 , Issue.4 , pp. 251-256
    • Starling, R.D.1    Liu, X.2    Sullivan, D.H.3
  • 127
    • 84855316344 scopus 로고    scopus 로고
    • Comparison of efficacy and safety of rimonabant with orlistat in obese and overweight patients
    • Suyog J, Milind P, Karuna R. Comparison of efficacy and safety of rimonabant with orlistat in obese and overweight patients. International Journal of Pharma and Bio Sciences 2011;2(1):179-87.
    • (2011) International Journal of Pharma and Bio Sciences , vol.2 , Issue.1 , pp. 179-187
    • Suyog, J.1    Milind, P.2    Karuna, R.3
  • 130
    • 0141651621 scopus 로고    scopus 로고
    • Sibutramine enhances insulin sensitivity ameliorating metabolic parameters in a double-blind, randomized, placebo-controlled trial
    • Tambascia MA, Geloneze B, Repetto EM, Geloneze SR, Picolo M, Magro DO. Sibutramine enhances insulin sensitivity ameliorating metabolic parameters in a double-blind, randomized, placebo-controlled trial. Diabetes, Obesity & Metabolism 2003;5(5):338-44.
    • (2003) Diabetes, Obesity & Metabolism , vol.5 , Issue.5 , pp. 338-344
    • Tambascia, M.A.1    Geloneze, B.2    Repetto, E.M.3    Geloneze, S.R.4    Picolo, M.5    Magro, D.O.6
  • 131
    • 3242746341 scopus 로고    scopus 로고
    • Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women
    • Tiikkainen M, Bergholm R, Rissanen A, Aro A, Salminen I, Tamminen M, et al. Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women. American Journal of Clinical Nutrition 2004;79(1):22-30.
    • (2004) American Journal of Clinical Nutrition , vol.79 , Issue.1 , pp. 22-30
    • Tiikkainen, M.1    Bergholm, R.2    Rissanen, A.3    Aro, A.4    Salminen, I.5    Tamminen, M.6
  • 132
    • 84863230015 scopus 로고    scopus 로고
    • Does rimonabant independently affect free fatty acid and glucose metabolism?
    • Triay J, Mundi M, Klein S, Toledo F G, Smith S R, Abu-Lebdeh H, et al. Does rimonabant independently affect free fatty acid and glucose metabolism?. JCEM 2012;97(3):819-27.
    • (2012) JCEM , vol.97 , Issue.3 , pp. 819-827
    • Triay, J.1    Mundi, M.2    Klein, S.3    Toledo, F.G.4    Smith, S.R.5    Abu-Lebdeh, H.6
  • 133
    • 85027091389 scopus 로고    scopus 로고
    • Cardioprotective effects of antihypertensive therapy with orlistat treatment and hypocaloric diet in combination in obese hypertensive patients
    • [CENTRAL: CN-00868400]
    • Tunyan AM. Cardioprotective effects of antihypertensive therapy with orlistat treatment and hypocaloric diet in combination in obese hypertensive patients. Circulation 2007;115(8):E248. [CENTRAL: CN-00868400]
    • (2007) Circulation , vol.115 , Issue.8 , pp. E248
    • Tunyan, A.M.1
  • 134
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study [see comment] [erratum appears in Lancet 2005 Jul 30-Aug 5;366(9483):370]
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S, RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study [see comment] [erratum appears in Lancet 2005 Jul 30-Aug 5;366(9483):370]. The Lancet 2005;365(9468):1389-97.
    • (2005) The Lancet , vol.365 , Issue.9468 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 135
    • 42449136138 scopus 로고    scopus 로고
    • Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study
    • Van Gaal LF, Scheen AJ, Rissanen AM, Rossner S, Hanotin C, Ziegler O, et al. Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study. European Heart Journal 2008;29(14):1761-71.
    • (2008) European Heart Journal , vol.29 , Issue.14 , pp. 1761-1771
    • Van Gaal, L.F.1    Scheen, A.J.2    Rissanen, A.M.3    Rossner, S.4    Hanotin, C.5    Ziegler, O.6
  • 137
    • 85027090445 scopus 로고    scopus 로고
    • The effects of once-daily 15mg phentermine plus 92mg topiramate extended-release (PHEN/TPM ER) on cardiometabolic endpoints in obese patients with obstructive sleep apnea
    • EMBASE: 71513682]
    • Winslow DH, Bowden CH, DiDonato K, McCullough PA. The effects of once-daily 15mg phentermine plus 92mg topiramate extended-release (PHEN/TPM ER) on cardiometabolic endpoints in obese patients with obstructive sleep apnea. Sleep 2013;36:A297. [EMBASE: 71513682]
    • (2013) Sleep , vol.36 , pp. A297
    • Winslow, D.H.1    Bowden, C.H.2    DiDonato, K.3    McCullough, P.A.4
  • 138
    • 84868277159 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of an oral, extended-release formulation of phentermine/topiramate for the treatment of obstructive sleep apnea in obese adults
    • PUBMED: 23115402]
    • Winslow DH, Bowden CH, DiDonato KP, McCullough PA. A randomized, double-blind, placebo-controlled study of an oral, extended-release formulation of phentermine/topiramate for the treatment of obstructive sleep apnea in obese adults. Sleep 2012;35:1529-39. [PUBMED: 23115402]
    • (2012) Sleep , vol.35 , pp. 1529-1539
    • Winslow, D.H.1    Bowden, C.H.2    DiDonato, K.P.3    McCullough, P.A.4
  • 139
    • 0035913584 scopus 로고    scopus 로고
    • Long-term weight loss with sibutramine: a randomized controlled trial
    • Wirth A, Krause J. Long-term weight loss with sibutramine: a randomized controlled trial. JAMA 2001;286(11):1331-9.
    • (2001) JAMA , vol.286 , Issue.11 , pp. 1331-1339
    • Wirth, A.1    Krause, J.2
  • 140
    • 0036733520 scopus 로고    scopus 로고
    • Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction
    • Zannad F, Gille B, Grentzinger A, Bruntz JF, Hammadi M, Boivin JM, et al. Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction. American Heart Journal 2002;144(3):508-15.
    • (2002) American Heart Journal , vol.144 , Issue.3 , pp. 508-515
    • Zannad, F.1    Gille, B.2    Grentzinger, A.3    Bruntz, J.F.4    Hammadi, M.5    Boivin, J.M.6
  • 141
    • 0032408205 scopus 로고    scopus 로고
    • Treatment with orlistat reduces cardiovascular risk in obese patients
    • Zavoral JH. Treatment with orlistat reduces cardiovascular risk in obese patients. Journal of Hypertension 1998;16(12 Pt 2):2013-7.
    • (1998) Journal of Hypertension , vol.16 , Issue.12 , pp. 2013-2017
    • Zavoral, J.H.1
  • 142
    • 84961912230 scopus 로고    scopus 로고
    • TM) trial: Rationale and study design
    • [EMBASE: 70695949]
    • TM) trial: Rationale and study design. Diabetic Medicine 2012;29:68. [EMBASE: 70695949]
    • (2012) Diabetic Medicine , vol.29 , pp. 68
    • Bain, S.C.1    Petrie, J.2
  • 144
    • 84961901083 scopus 로고    scopus 로고
    • Liraglutide effect and action in diabetes: Evaluation of cardiovascular outcome results (leader) trial: Rationale and study design
    • EMBASE: 713987964]
    • Consoli A, Bergenstal R, Daniels G, Mann J, Nissen S, Pocock S, et al. Liraglutide effect and action in diabetes: Evaluation of cardiovascular outcome results (leader) trial: Rationale and study design. High Blood Pressure and Cardiovascular Prevention 2012;19(2):104. [EMBASE: 713987964]
    • (2012) High Blood Pressure and Cardiovascular Prevention , vol.19 , Issue.2 , pp. 104
    • Consoli, A.1    Bergenstal, R.2    Daniels, G.3    Mann, J.4    Nissen, S.5    Pocock, S.6
  • 145
    • 84961889682 scopus 로고    scopus 로고
    • Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results (LEADER) Trial: Rationale and study design
    • EMBASE: 70799751]
    • Mannucci E, Bergenstal R, Daniels G, Mann J, Nissen S, Zinman B, et al. Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results (LEADER) Trial: Rationale and study design. Italian Journal of Medicine 2012;6(1, Suppl 1):86. [EMBASE: 70799751]
    • (2012) Italian Journal of Medicine , vol.6 , Issue.1 , pp. 86
    • Mannucci, E.1    Bergenstal, R.2    Daniels, G.3    Mann, J.4    Nissen, S.5    Zinman, B.6
  • 146
    • 84886946727 scopus 로고    scopus 로고
    • Design of the liraglutide effect and action in diabetes: Evaluation of cardiovascular outcome results (LEADER) trial
    • EMBASE: 2013691152]
    • Marso SP, Poulter NR, Nissen SE, Nauck MA, Zinman B, Daniels GH, et al. Design of the liraglutide effect and action in diabetes: Evaluation of cardiovascular outcome results (LEADER) trial. American Heart Journal 2013;166:823-30. [EMBASE: 2013691152]
    • (2013) American Heart Journal , vol.166 , pp. 823-830
    • Marso, S.P.1    Poulter, N.R.2    Nissen, S.E.3    Nauck, M.A.4    Zinman, B.5    Daniels, G.H.6
  • 147
    • 84961875356 scopus 로고    scopus 로고
    • Press release: [Abbott setzt Vertrieb seiner Medikamente mit dem Wirkstoff Sibutramin zur Behandlung von Adipositas in den Ländern der Europäischen Union aus.] 2010
    • (cited 14 January 2013)
    • Abbott Germany. Theobald F. Press release: [Abbott setzt Vertrieb seiner Medikamente mit dem Wirkstoff Sibutramin zur Behandlung von Adipositas in den Ländern der Europäischen Union aus.] 2010. Available from: http://www.abbott.de/press/show/e7340/e19695/e18095/Sibutramin_210110_Theobald_de.pdf (cited 14 January 2013).
    • Available from: http://www.abbott.de/press/show/e7340/e19695/e18095/Sibutramin_210110_Theobald_de.pdf
    • Theobald, F.1
  • 149
    • 84887155139 scopus 로고    scopus 로고
    • Evaluation of phentermine and topiramate versus phentermine/topiramate extended-release in obese adults
    • PUBMED: 24136928]
    • Aronne LJ, Wadden TA, Peterson C, Winslow D, Odeh S, Gadde KM. Evaluation of phentermine and topiramate versus phentermine/topiramate extended-release in obese adults. Obesity (Silver Spring, Md.) 2013;21(11):2163-71. [PUBMED: 24136928]
    • (2013) Obesity (Silver Spring, Md.) , vol.21 , Issue.11 , pp. 2163-2171
    • Aronne, L.J.1    Wadden, T.A.2    Peterson, C.3    Winslow, D.4    Odeh, S.5    Gadde, K.M.6
  • 150
    • 20044371999 scopus 로고    scopus 로고
    • Effects of weight loss in overweight/obese individuals and long-term hypertension outcomes: a systematic review
    • PUBMED: 15897373]
    • Aucott L, Poobalan A, Smith WC, Avenell A, Jung R, Broom J. Effects of weight loss in overweight/obese individuals and long-term hypertension outcomes: a systematic review. Hypertension 2005;45(6):1035-41. [PUBMED: 15897373]
    • (2005) Hypertension , vol.45 , Issue.6 , pp. 1035-1041
    • Aucott, L.1    Poobalan, A.2    Smith, W.C.3    Avenell, A.4    Jung, R.5    Broom, J.6
  • 151
    • 84908055935 scopus 로고    scopus 로고
    • Naltrexone sustained-release/bupropion sustained-release for the management of obesity: review of the data to date
    • PUBMED: 25258511]
    • Caixas A, Albert L, Capel I, Rigla M. Naltrexone sustained-release/bupropion sustained-release for the management of obesity: review of the data to date. Drug Design, Development and Therapy 2014;8:1419-27. [PUBMED: 25258511]
    • (2014) Drug Design, Development and Therapy , vol.8 , pp. 1419-1427
    • Caixas, A.1    Albert, L.2    Capel, I.3    Rigla, M.4
  • 153
    • 84899658037 scopus 로고    scopus 로고
    • The 2014 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension
    • PUBMED: 24786438]
    • Dasgupta K, Quinn RR, Zarnke KB, Rabi DM, Ravani P, Daskalopoulou SS, et al. The 2014 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Canadian Journal of Cardiology 2014;30(5):485-501. [PUBMED: 24786438]
    • (2014) Canadian Journal of Cardiology , vol.30 , Issue.5 , pp. 485-501
    • Dasgupta, K.1    Quinn, R.R.2    Zarnke, K.B.3    Rabi, D.M.4    Ravani, P.5    Daskalopoulou, S.S.6
  • 154
    • 77956017429 scopus 로고    scopus 로고
    • Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial
    • PUBMED: 20709233]
    • Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, et al. Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial. The Lancet 2010;376(9740):517-23. [PUBMED: 20709233]
    • (2010) The Lancet , vol.376 , Issue.9740 , pp. 517-523
    • Topol, E.J.1    Bousser, M.G.2    Fox, K.A.3    Creager, M.A.4    Despres, J.P.5    Easton, J.D.6
  • 155
    • 12744260207 scopus 로고    scopus 로고
    • Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients
    • PUBMED: 15642075]
    • Derosa G, Cicero AF, Murdolo G, Piccinni MN, Fogari E, Bertone G, et al. Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients. Diabetes, Obesity & Metabolism 2005;7(1):47-55. [PUBMED: 15642075]
    • (2005) Diabetes, Obesity & Metabolism , vol.7 , Issue.1 , pp. 47-55
    • Derosa, G.1    Cicero, A.F.2    Murdolo, G.3    Piccinni, M.N.4    Fogari, E.5    Bertone, G.6
  • 156
    • 84961937574 scopus 로고    scopus 로고
    • Questions and answers on the recommendation to suspend the marketing authorisation of Acomplia (rimonabant)
    • (updated 23 October 2008; cited 17 December 2012)
    • European Medicines Agency (EMA). Questions and answers on the recommendation to suspend the marketing authorisation of Acomplia (rimonabant). Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Medicine_QA/2009/11/WC500014779.pdf (updated 23 October 2008; cited 17 December 2012).
    • Available from:
  • 157
    • 84961889676 scopus 로고    scopus 로고
    • Press Release - The European Medicines Agency recommends suspension of the marketing authorisation of Acomplia
    • (updated 23 October 2008; cited 17 December 2012)
    • European Medicines Agency (EMA). Press Release - The European Medicines Agency recommends suspension of the marketing authorisation of Acomplia. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Press_release/2009/11/WC500014774.pdf (updated 23 October 2008; cited 17 December 2012).
    • Available from:
  • 158
    • 84961901084 scopus 로고    scopus 로고
    • Public Statement on Acomplia (rimonabant) - Withdrawal of the marketing authorisation in the European Union
    • (updated 30 January 2009; cited 17 December 2012)
    • European Medicines Agency (EMA). Public Statement on Acomplia (rimonabant) - Withdrawal of the marketing authorisation in the European Union. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Public_statement/2009/11/WC500012189.pdf (updated 30 January 2009; cited 17 December 2012).
    • Available from:
  • 159
    • 84961889686 scopus 로고    scopus 로고
    • Victoza (liraglutide) - EPAR - Summary for the public
    • (updated 8 July 2009; cited 17 December 2012)
    • European Medicines Agency (EMA). Victoza (liraglutide) - EPAR - Summary for the public. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Summary_for_the_public/human/001026/WC500050013.pdf (updated 8 July 2009; cited 17 December 2012).
    • Available from:
  • 160
    • 84961901077 scopus 로고    scopus 로고
    • Press Release - European Medicines Agency recommends suspension of marketing authorisations for sibutramine
    • (updated 21 January 2010; cited 17 December 2012)
    • European Medicines Agency (EMA). Press Release - European Medicines Agency recommends suspension of marketing authorisations for sibutramine. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Press_release/2010/01/WC500069995.pdf (updated 21 January 2010; cited 17 December 2012).
    • Available from:
  • 161
    • 84961889677 scopus 로고    scopus 로고
    • Questions and answers on the suspension of medicines containing sibutramine
    • (updated 6 August 2010; cited 17 December 2012)
    • European Medicines Agency (EMA). Questions and answers on the suspension of medicines containing sibutramine. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Sibutramine_107/WC500094238.pdf (updated 6 August 2010; cited 17 December 2012).
    • Available from:
  • 162
    • 84961902686 scopus 로고    scopus 로고
    • Questions and answers on the withdrawal of the marketing authorisation application for Belviq (lorcaserin)
    • (updated 31 May 2013; cited 20 July 2015)
    • European Medicines Agency (EMA). Questions and answers on the withdrawal of the marketing authorisation application for Belviq (lorcaserin). Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Medicine_QA/2013/05/WC500143811.pdf (updated 31 May 2013; cited 20 July 2015).
    • Available from:
  • 163
    • 84961889595 scopus 로고    scopus 로고
    • Withdrawal assessment report for Belviq
    • (updated 20 August 2013; cited 20 July 2015)
    • European Medicines Agency (EMA). Withdrawal assessment report for Belviq. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Application_withdrawal_assessment_report/human/002597/WC500148196.pdf (updated 20 August 2013; cited 20 July 2015).
    • Available from:
  • 164
    • 84961969438 scopus 로고    scopus 로고
    • Questions and answers on the refusal of the marketing authorisation for Qsiva (phentermine/topiramate)
    • (updated 22 February 2013; cited 20 July 2015)
    • European Medicines Agency (EMA). Questions and answers on the refusal of the marketing authorisation for Qsiva (phentermine/topiramate). Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion_-_Initial_authorisation/human/002350/WC500139215.pdf (updated 22 February 2013; cited 20 July 2015).
    • Available from:
  • 165
    • 84961969423 scopus 로고    scopus 로고
    • Scientific conclusions and grounds for refusal of the marketing authorisation for Qsiva (13 June 2013)
    • (updated 13 June 2013; cited 20 July 2015)
    • European Medicines Agency (EMA). Scientific conclusions and grounds for refusal of the marketing authorisation for Qsiva (13 June 2013). Available from: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002350/human_med_001607.jsp&mid=WC0b01ac058001d124# (updated 13 June 2013; cited 20 July 2015).
    • Available from:
  • 166
    • 84961934481 scopus 로고    scopus 로고
    • Mysimba (naltrexone/bupropion) - EPAR summary for the public
    • (updated 15 April 2015; cited 20 July 2015)
    • European Medicines Agency (EMA). Mysimba (naltrexone/bupropion) - EPAR summary for the public. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Summary_for_the_public/human/003687/WC500185583.pdf (updated 15 April 2015; cited 20 July 2015).
    • Available from:
  • 167
    • 84961929756 scopus 로고    scopus 로고
    • Saxenda (liraglutide) - EPAR summary for the public
    • (updated 16 April 2015; cited 20 July 2015)
    • European Medicines Agency (EMA). Saxenda (liraglutide) - EPAR summary for the public. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Summary_for_the_public/human/003780/WC500185789.pdf (updated 16 April 2015; cited 20 July 2015).
    • Available from:
  • 168
    • 84896724318 scopus 로고    scopus 로고
    • 2013 ESH/ESC Practice Guidelines for the Management of Arterial Hypertension
    • PUBMED: 24359485]
    • Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Bohm M, et al. 2013 ESH/ESC Practice Guidelines for the Management of Arterial Hypertension. Blood Pressure 2014;23(1):3-16. [PUBMED: 24359485]
    • (2014) Blood Pressure , vol.23 , Issue.1 , pp. 3-16
    • Mancia, G.1    Fagard, R.2    Narkiewicz, K.3    Redon, J.4    Zanchetti, A.5    Bohm, M.6
  • 169
    • 84961887414 scopus 로고    scopus 로고
    • FDA Rimonabant Briefing Document. Endocrine and Metabolic Drugs Advisory Committee. 2007
    • (updated 13 June 2007; cited 18 December 2012)
    • US Food, Drug Administration. Egan AG. Colman EG. FDA Rimonabant Briefing Document. Endocrine and Metabolic Drugs Advisory Committee. 2007. Available from: http://www.fda.gov/ohrms/dockets/AC/07/briefing/2007-4306b1-fda-backgrounder.pdf (updated 13 June 2007; cited 18 December 2012).
    • Available from:
    • Egan, A.G.1    Colman, E.G.2
  • 170
    • 84961909424 scopus 로고    scopus 로고
    • Recommendation on a regulatory decision for Meridia (sibutramine)
    • (updated 7 October 2010; cited 18 December 2012)
    • US Food, Drug Administration (FDA). Recommendation on a regulatory decision for Meridia (sibutramine). Available from: http://www.fda.gov/downloads/Drugs/DrugSafety/UCM228795.pdf (updated 7 October 2010; cited 18 December 2012).
    • Available from
  • 171
    • 84961968610 scopus 로고    scopus 로고
    • FDA News Release: Abbott Laboratories agrees to withdraw its obesity drug Meridia
    • (updated 8 October 2010; cited 18 December 2012)
    • US Food, Drug Administration (FDA). FDA News Release: Abbott Laboratories agrees to withdraw its obesity drug Meridia. Available from: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2010/ucm228812.htm (updated 8 October 2010; cited 18 December 2012).
    • Available from: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2010/ucm228812.htm
  • 177
    • 84961916766 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011
    • Higgins JPT, Green S(editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
    • Available from www.cochrane-handbook.org
    • Higgins, J.P.T.1    Green, S.2
  • 178
    • 41549096849 scopus 로고    scopus 로고
    • Long-term effects of weight-reducing interventions in hypertensive patients: systematic review and meta-analysis
    • PUBMED: 18362248]
    • Horvath K, Jeitler K, Siering U, Stich AK, Skipka G, Gratzer TW, et al. Long-term effects of weight-reducing interventions in hypertensive patients: systematic review and meta-analysis. Archives of Internal Medicine 2008;168(6):571-80. [PUBMED: 18362248]
    • (2008) Archives of Internal Medicine , vol.168 , Issue.6 , pp. 571-580
    • Horvath, K.1    Jeitler, K.2    Siering, U.3    Stich, A.K.4    Skipka, G.5    Gratzer, T.W.6
  • 179
    • 84961875334 scopus 로고    scopus 로고
    • Evaluation of the benefits and harms of non-drug weight-reducing treatment strategies in patients with essential hypertension
    • [Nutzenbewertung nichtmedikamentöser Behandlungsstrategien bei Patienten mit Bluthochdruck: A-Gewichtsreduktion].. Köln: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)
    • Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG). Evaluation of the benefits and harms of non-drug weight-reducing treatment strategies in patients with essential hypertension [Nutzenbewertung nichtmedikamentöser Behandlungsstrategien bei Patienten mit Bluthochdruck: A-Gewichtsreduktion]. Available from: http://iqwig.de/download/A05-21A_Abschlussbericht_Gewichtsreduktion_bei_Bluthochdruck_neu.pdf. Köln: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG), 2006:19-119.
    • (2006) Available from: http://iqwig.de/download/A05-21A_Abschlussbericht_Gewichtsreduktion_bei_Bluthochdruck_neu.pdf , pp. 19-119
    • Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, (IQW.1
  • 180
    • 84893549987 scopus 로고    scopus 로고
    • 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
    • PUBMED: 24352797]
    • James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311(5):507-20. [PUBMED: 24352797]
    • (2014) JAMA , vol.311 , Issue.5 , pp. 507-520
    • James, P.A.1    Oparil, S.2    Carter, B.L.3    Cushman, W.C.4    Dennison-Himmelfarb, C.5    Handler, J.6
  • 181
    • 1542390739 scopus 로고    scopus 로고
    • Effect of sibutramine on weight loss and blood pressure: a meta-analysis of controlled trials
    • PUBMED: 12972682]
    • Kim SH, Lee YM, Jee SH, Nam CM. Effect of sibutramine on weight loss and blood pressure: a meta-analysis of controlled trials. Obesity Research 2003;11(9):1116-23. [PUBMED: 12972682]
    • (2003) Obesity Research , vol.11 , Issue.9 , pp. 1116-1123
    • Kim, S.H.1    Lee, Y.M.2    Jee, S.H.3    Nam, C.M.4
  • 183
    • 84961902683 scopus 로고    scopus 로고
    • Hypertension - The clinical management of primary hypertension in adults; Clinical Guideline 127. 2011
    • (updated August 2011; cited 18 December 2012)
    • National Institute for Health and Clinical Excellence (NICE). Hypertension - The clinical management of primary hypertension in adults; Clinical Guideline 127. 2011. Available from: http://www.nice.org.uk/nicemedia/live/13561/56007/56007.pdf (updated August 2011; cited 18 December 2012).
    • Available from: http://www.nice.org.uk/nicemedia/live/13561/56007/56007.pdf
  • 184
    • 33845874637 scopus 로고    scopus 로고
    • Drug treatments for obesity: orlistat, sibutramine, and rimonabant
    • [PUBMED: 17208644]
    • Padwal RS, Majumdar SR. Drug treatments for obesity: orlistat, sibutramine, and rimonabant. The Lancet 2007;369(9555):71-7. [PUBMED: 17208644]
    • (2007) The Lancet , vol.369 , Issue.9555 , pp. 71-77
    • Padwal, R.S.1    Majumdar, S.R.2
  • 185
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • PUBMED: 19622511]
    • Moher D, Liberati A, Tetzlaff J, Altman D G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of Internal Medicine 2009;151(4):264-9, W64. [PUBMED: 19622511]
    • (2009) Annals of Internal Medicine , vol.151 , Issue.4
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 186
    • 37249083878 scopus 로고    scopus 로고
    • Long term pharmacotherapy for obesity and overweight: updated meta-analysis
    • PUBMED: 18006966]
    • Rucker D, Padwal R, Li SK, Curioni C, Lau DC. Long term pharmacotherapy for obesity and overweight: updated meta-analysis. BMJ 2007;335(7631):1194-9. [PUBMED: 18006966]
    • (2007) BMJ , vol.335 , Issue.7631 , pp. 1194-1199
    • Rucker, D.1    Padwal, R.2    Li, S.K.3    Curioni, C.4    Lau, D.C.5
  • 187
    • 57649232757 scopus 로고    scopus 로고
    • Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue
    • [PUBMED: 19041364]
    • Russell-Jones D. Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue. Molecular and Cellular Endocrinology 2009;297(1-2):137-40. [PUBMED: 19041364]
    • (2009) Molecular and Cellular Endocrinology , vol.297 , Issue.1-2 , pp. 137-140
    • Russell-Jones, D.1
  • 188
    • 33751001942 scopus 로고    scopus 로고
    • Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study
    • PUBMED: 17098084]
    • Scheen AJ, Finer N, Hollander P, Jensen MD, Van Gaal LF. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. The Lancet 2006;368(9548):1660-72. [PUBMED: 17098084]
    • (2006) The Lancet , vol.368 , Issue.9548 , pp. 1660-1672
    • Scheen, A.J.1    Finer, N.2    Hollander, P.3    Jensen, M.D.4    Van Gaal, L.F.5
  • 191
    • 84961969409 scopus 로고    scopus 로고
    • Clinical guidelines for the management of hypertension. WHO EMRO Technical Publication Series 29. 2005
    • (cited 14 January 2013)
    • World Health Organization. Khatib OMN, El-Guindy MS (editors). Clinical guidelines for the management of hypertension. WHO EMRO Technical Publication Series 29. 2005. Available from: http://www.emro.who.int/dsaf/dsa234.pdf (cited 14 January 2013).
    • Available from: http://www.emro.who.int/dsaf/dsa234.pdf
    • Khatib, O.M.N.1    El-Guindy, M.S.2
  • 193
    • 84891919414 scopus 로고    scopus 로고
    • Long-term drug treatment for obesity: a systematic and clinical review
    • [PUBMED: 24231879]
    • Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA 2014;311(1):74-86. [PUBMED: 24231879]
    • (2014) JAMA , vol.311 , Issue.1 , pp. 74-86
    • Yanovski, S.Z.1    Yanovski, J.A.2
  • 194
    • 84928211618 scopus 로고    scopus 로고
    • Weight loss effect of glucagon-like peptide-1 mimetics on obese/overweight adults without diabetes: A systematic review and meta-analysis of randomized controlled trials
    • PUBMED: 25043423]
    • Zhang F, Tong Y, Su N, Li Y, Tang L, Huang L, et al. Weight loss effect of glucagon-like peptide-1 mimetics on obese/overweight adults without diabetes: A systematic review and meta-analysis of randomized controlled trials. Journal of Diabetes 2015;7(3):329-39. [PUBMED: 25043423]
    • (2015) Journal of Diabetes , vol.7 , Issue.3 , pp. 329-339
    • Zhang, F.1    Tong, Y.2    Su, N.3    Li, Y.4    Tang, L.5    Huang, L.6


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