CCR4 frameshift mutation identifies a distinct group of adult T cell leukaemia/lymphoma with poor prognosis

Journal of Pathology

Volumn 238, Issue 5, 2016, Pages 621-626

  Yoshida, Noriaki ^a,g   Miyoshi, Hiroaki ^a   Kato, Takeharu ^a,b   Sakata Yanagimoto, Mamiko ^c   Niino, Daisuke ^a,h   Taniguchi, Hiroaki ^d   Moriuchi, Yukiyoshi ^d   Miyahara, Masaharu ^e   Kurita, Daisuke ^a   Sasaki, Yuya ^a   Shimono, Joji ^a   Kawamoto, Keisuke ^a   Utsunomiya, Atae ^f   Imaizumi, Yoshitaka ^b   Seto, Masao ^a   Ohshima, Koichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d Sasebo Shiritsu Sogo Hospital   (Japan)

^e KARATSU RED CROSS HOSPITAL   (Japan)

^f Imamura Bun in Hospital   (Japan)

^g HARVARD MEDICAL SCHOOL   (United States)

^h NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

adult T cell leukaemia lymphoma; CCR4 mutation; clinicopathological analyses; prognostic impact; tissue array

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CCR4 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; ANGIOIMMUNOBLASTIC T CELL LYMPHOMA; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; DISEASE COURSE; FRAMESHIFT MUTATION; GENE SEQUENCE; HUMAN; HUMAN T-LYMPHOTROPIC VIRUS 1; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; MUTATION RATE; NEXT GENERATION SEQUENCING; NONHUMAN; NONSENSE MUTATION; OVERALL SURVIVAL; PERIPHERAL T CELL LYMPHOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS; T CELL LEUKEMIA; WILD TYPE; AGED; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION; GENETICS; KAPLAN MEIER METHOD; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PHENOTYPE; PROGNOSIS; TIME FACTOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; DNA MUTATIONAL ANALYSIS; FEMALE; FRAMESHIFT MUTATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MALE; MIDDLE AGED; PHENOTYPE; PROGNOSIS; RECEPTORS, CCR4; TIME FACTORS;

EID: 84961771236     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4699     Document Type: Article

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