Association between adiponectin gene T45G polymorphism and nonalcoholic fatty liver disease risk: A meta-analysis

Genetics and Molecular Research

Volumn 15, Issue 1, 2016, Pages

  Zhang, W ^a   Zhu, L Q ^a   Huo, X L ^b   Qin, J ^b   Yuan, G Y ^a  

^a AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

^b Department of Gastroenterology   (China)

Author keywords

Adiponectin; Meta analysis; Nonalcoholic fatty liver disease; Polymorphism

Indexed keywords

ADIPONECTIN; GLYCINE; THREONINE; ADIPOQ PROTEIN, HUMAN;

ADIPONECTIN GENE; ARTICLE; ASIAN; CAUCASIAN; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATIONAL STUDY; DATA ANALYSIS; ETHNICITY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; NONALCOHOLIC FATTY LIVER; ODDS RATIO; RISK FACTOR; SENSITIVITY ANALYSIS; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MODEL; CASE CONTROL STUDY; ETHNOLOGY; GENE EXPRESSION; GENETICS; META ANALYSIS; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADIPONECTIN; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION; GENOTYPE; HUMANS; MODELS, GENETIC; NON-ALCOHOLIC FATTY LIVER DISEASE; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84961683134     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/gmr.15017190     Document Type: Article

References (18)

1. Ahmed M (2015). Non-alcoholic fatty liver disease in 2015. World J. Hepatol. 7: 1450-1459. http://dx.doi.org/10.4254/wjh. v7. i11. 1450
2. Brochu-Gaudreau K, Rehfeldt C, Blouin R, Bordignon V, et al. (2010). Adiponectin action from head to toe. Endocrine 37: 11- 32. http://dx.doi.org/10.1007/s12020-009-9278-8
3. Della Corte C, Alisi A, Saccari A, De Vito R, et al. (2012). Nonalcoholic fatty liver in children and adolescents: an overview. J. Adolesc. Health 51: 305-312. http://dx.doi.org/10.1016/j. jadohealth. 2012. 01. 010
4. Farrell GC and Larter CZ (2006). Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43 (Suppl 1): S99-S112. http://dx.doi.org/10.1002/hep. 20973
5. Gable DR, Hurel SJ and Humphries SE (2006). Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease. Atherosclerosis 188: 231-244. http://dx.doi.org/10.1016/j. atherosclerosis. 2006. 02. 010
6. Gao L, Zhang Y, Cui Y, Jiang Y, et al. (2012). Association of the T45G and G276T polymorphisms in the adiponectin gene with PCOS: A meta-analysis. Gynecol. Endocrinol. 28: 106-110. http://dx.doi.org/10.3109/09513590. 2010. 508543
7. Gupta AC, Misra R, Sakhuja P, Singh Y, et al. (2012). Association of adiponectin gene functional polymorphisms (-11377C/G and +45T/G) with nonalcoholic fatty liver disease. Gene 496: 63-67. http://dx.doi.org/10.1016/j. gene. 2011. 12. 023
8. Higgins JP and Thompson SG (2002). Quantifying heterogeneity in a meta-analysis. Stat. Med. 21: 1539-1558. http://dx.doi.org/10.1002/sim. 1186
9. Hotta K, Funahashi T, Arita Y, Takahashi M, et al. (2000). Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler. Thromb. Vasc. Biol. 20: 1595-1599. http://dx.doi.org/10.1161/01. ATV. 20. 6. 1595
10. Li L, Wang SJ, Shi K, Chen D, et al. (2014). Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis. Genet. Mol. Res. 13: 10150-10161. http://dx.doi.org/10.4238/2014. December. 4. 9
11. Li LL, Kang XL, Ran XJ, Wang Y, et al. (2007). Associations between 45T/G polymorphism of the adiponectin gene and plasma adiponectin levels with type 2 diabetes. Clin. Exp. Pharmacol. Physiol. 34: 1287-1290. http://dx.doi.org/10.1111/j. 1440-1681. 2007. 04713. x
12. Musso G, Gambino R, De Michieli F, Durazzo M, et al. (2008). Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: Possible pathogenetic role in NASH. Hepatology 47: 1167-1177. http://dx.doi.org/10.1002/hep. 22142
13. Romeo S, Kozlitina J, Xing C, Pertsemlidis A, et al. (2008). Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat. Genet. 40: 1461-1465. http://dx.doi.org/10.1038/ng. 257
14. Shimabukuro M, Higa M, Yamakawa K, Masuzaki H, et al. (2013). Miglitol, α-glycosidase inhibitor, reduces visceral fat accumulation and cardiovascular risk factors in subjects with the metabolic syndrome: a randomized comparable study. Int. J. Cardiol. 167: 2108-2113. http://dx.doi.org/10.1016/j. ijcard. 2012. 05. 109
15. Tokushige K, Hashimoto E, Noto H, Yatsuji S, et al. (2009). Influence of adiponectin gene polymorphisms in Japanese patients with non-alcoholic fatty liver disease. J. Gastroenterol. 44: 976-982. http://dx.doi.org/10.1007/s00535-009-0085-z
16. Wang ZL, Xia B, Shrestha U, Jiang L, et al. (2008). Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population. J. Endocrinol. Invest. 31: 1086-1091. http://dx.doi.org/10.1007/BF03345657
17. Wong VW, Wong GL, Yip GW, Lo AO, et al. (2011). Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease. Gut 60: 1721-1727. http://dx.doi.org/10.1136/gut. 2011. 242016
18. Zhou YJ, Li YY, Nie YQ, Yang H, et al. (2010). Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people. J. Gastroenterol. Hepatol. 25: 772-777. http://dx.doi.org/10.1111/j. 1440-1746. 2009. 06144. x