-
1
-
-
84954026435
-
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
-
Le Tourneau C, Delord JP, Goncalves A, et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet Oncol 2015, 16:1324-1334.
-
(2015)
Lancet Oncol
, vol.16
, pp. 1324-1334
-
-
Le Tourneau, C.1
Delord, J.P.2
Goncalves, A.3
-
2
-
-
84895906492
-
Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors
-
Janku F, Hong DS, Fu S, et al. Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors. Cell Rep 2014, 6:377-387.
-
(2014)
Cell Rep
, vol.6
, pp. 377-387
-
-
Janku, F.1
Hong, D.S.2
Fu, S.3
-
3
-
-
51149092061
-
The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2
-
Prat A, Baselga J The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2. Nat Clin Pract Oncol 2008, 5:531-542.
-
(2008)
Nat Clin Pract Oncol
, vol.5
, pp. 531-542
-
-
Prat, A.1
Baselga, J.2
-
4
-
-
0344442314
-
RET tyrosine kinase and medullary thyroid cells are unaffected by clinical doses of STI571
-
Skinner MA, Safford SD, Freemerman AJ RET tyrosine kinase and medullary thyroid cells are unaffected by clinical doses of STI571. Anticancer Res 2003, 23:3601-3606.
-
(2003)
Anticancer Res
, vol.23
, pp. 3601-3606
-
-
Skinner, M.A.1
Safford, S.D.2
Freemerman, A.J.3
-
5
-
-
79951906119
-
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers
-
Von Hoff DD, Stephenson JJ, Rosen P, et al. Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 2010, 28:4877-4883.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4877-4883
-
-
Von Hoff, D.D.1
Stephenson, J.J.2
Rosen, P.3
-
6
-
-
84869223443
-
Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative
-
Tsimberidou AM, Iskander NG, Hong DS, et al. Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative. Clin Cancer Res 2012, 18:6373-6383.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6373-6383
-
-
Tsimberidou, A.M.1
Iskander, N.G.2
Hong, D.S.3
-
7
-
-
84910651190
-
A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer
-
Jameson GS, Petricoin EF, Sachdev J, et al. A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer. Breast Cancer Res Treat 2014, 147:579-588.
-
(2014)
Breast Cancer Res Treat
, vol.147
, pp. 579-588
-
-
Jameson, G.S.1
Petricoin, E.F.2
Sachdev, J.3
-
8
-
-
84900829967
-
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
-
Kris MG, Johnson BE, Berry LD, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014, 311:1998-2006.
-
(2014)
JAMA
, vol.311
, pp. 1998-2006
-
-
Kris, M.G.1
Johnson, B.E.2
Berry, L.D.3
-
9
-
-
84939864059
-
Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations
-
Hyman DM, Puzanov I, Subbiah V, et al. Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations. N Engl J Med 2015, 373:726-736.
-
(2015)
N Engl J Med
, vol.373
, pp. 726-736
-
-
Hyman, D.M.1
Puzanov, I.2
Subbiah, V.3
-
10
-
-
84946053976
-
Impact of precision medicine in diverse cancers: a meta-analysis of phase II clinical trials
-
Schwaederle M, Zhao M, Lee JJ, et al. Impact of precision medicine in diverse cancers: a meta-analysis of phase II clinical trials. J Clin Oncol 2015, 33:3817-3825.
-
(2015)
J Clin Oncol
, vol.33
, pp. 3817-3825
-
-
Schwaederle, M.1
Zhao, M.2
Lee, J.J.3
-
11
-
-
84946208882
-
Impact of a biomarker-based strategy on oncology drug development: a meta-analysis of clinical trials leading to FDA approval
-
Fontes Jardim DL, Schwaederle M, Wei C, et al. Impact of a biomarker-based strategy on oncology drug development: a meta-analysis of clinical trials leading to FDA approval. J Natl Cancer Inst 2015, 107:djv253.
-
(2015)
J Natl Cancer Inst
, vol.107
, pp. djv253
-
-
Fontes Jardim, D.L.1
Schwaederle, M.2
Wei, C.3
|