-
2
-
-
34250755685
-
Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
-
Mamane Y, Petroulakis E, Martineau Y, Sato TA, Larsson O, Rajasekhar VK, Sonenberg N. Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation. PLoS One. 2007; 2:e242
-
(2007)
PLoS One
, vol.2
-
-
Mamane, Y.1
Petroulakis, E.2
Martineau, Y.3
Sato, T.A.4
Larsson, O.5
Rajasekhar, V.K.6
Sonenberg, N.7
-
3
-
-
34848901974
-
Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
-
Graff JR, Konicek BW, Vincent TM, Lynch RL, Monteith D, Weir SN, Schwier P, Capen A, Goode RL, Dowless MS, Chen Y, Zhang H, Sissons S, et al. Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity. J Clin Invest. 2007. 117:2638-2648
-
(2007)
J Clin Invest
, vol.117
, pp. 2638-2648
-
-
Graff, J.R.1
Konicek, B.W.2
Vincent, T.M.3
Lynch, R.L.4
Monteith, D.5
Weir, S.N.6
Schwier, P.7
Capen, A.8
Goode, R.L.9
Dowless, M.S.10
Chen, Y.11
Zhang, H.12
Sissons, S.13
-
4
-
-
2342489456
-
eIF-4E expression and its role in malignancies and metastases
-
De Benedetti A, Graff JR. eIF-4E expression and its role in malignancies and metastases. Oncogene. 2004; 23:3189-3199
-
(2004)
Oncogene
, vol.23
, pp. 3189-3199
-
-
De Benedetti, A.1
Graff, J.R.2
-
5
-
-
1642586272
-
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
-
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature. 2004; 428:332-337
-
(2004)
Nature
, vol.428
, pp. 332-337
-
-
Wendel, H.G.1
De Stanchina, E.2
Fridman, J.S.3
Malina, A.4
Ray, S.5
Kogan, S.6
Cordon-Cardo, C.7
Pelletier, J.8
Lowe, S.W.9
-
6
-
-
0035806992
-
Cell cycledependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)
-
Heesom KJ, Gampel A, Mellor H, Denton RM. Cell cycledependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1). Curr Biol. 2001; 11:1374-1379
-
(2001)
Curr Biol
, vol.11
, pp. 1374-1379
-
-
Heesom, K.J.1
Gampel, A.2
Mellor, H.3
Denton, R.M.4
-
7
-
-
9244228003
-
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
-
Topisirovic I, Ruiz-Gutierrez M, Borden KL. Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res. 2004; 64:8639-8642
-
(2004)
Cancer Res
, vol.64
, pp. 8639-8642
-
-
Topisirovic, I.1
Ruiz-Gutierrez, M.2
Borden, K.L.3
-
8
-
-
70350494540
-
p53-dependent translational control of senescence and transformation via 4E-BPs
-
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, et al. p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell. 2009; 16:439-446
-
(2009)
Cancer Cell
, vol.16
, pp. 439-446
-
-
Petroulakis, E.1
Parsyan, A.2
Dowling, R.J.3
LeBacquer, O.4
Martineau, Y.5
Bidinosti, M.6
Larsson, O.7
Alain, T.8
Rong, L.9
Mamane, Y.10
Paquet, M.11
Furic, L.12
Topisirovic, I.13
-
9
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010; 466:835-840
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
10
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005; 433:769-773
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
11
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
12
-
-
84928754032
-
MicroRNA control of protein expression noise
-
Schmiedel JM, Klemm SL, Zheng YN, Sahay A, Bluthgen N, Marks DS, van Oudenaarden A. MicroRNA control of protein expression noise. Science. 2015; 348:128-132
-
(2015)
Science
, vol.348
, pp. 128-132
-
-
Schmiedel, J.M.1
Klemm, S.L.2
Zheng, Y.N.3
Sahay, A.4
Bluthgen, N.5
Marks, D.S.6
van Oudenaarden, A.7
-
13
-
-
33746630543
-
MicroRNA control of lifespan and metabolism
-
Boehm M, Slack FJ. MicroRNA control of lifespan and metabolism. Cell Cycle. 2006; 5:837-840
-
(2006)
Cell Cycle
, vol.5
, pp. 837-840
-
-
Boehm, M.1
Slack, F.J.2
-
14
-
-
28444449496
-
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
-
Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 2005; 438:671-674
-
(2005)
Nature
, vol.438
, pp. 671-674
-
-
Hornstein, E.1
Mansfield, J.H.2
Yekta, S.3
Hu, J.K.4
Harfe, B.D.5
McManus, M.T.6
Baskerville, S.7
Bartel, D.P.8
Tabin, C.J.9
-
16
-
-
34548746977
-
MicroRNA signatures in human ovarian cancer
-
Iorio MV, Visone R, Di Leva G, Donati V, Petrocca F, Casalini P, Taccioli C, Volinia S, Liu CG, Alder H, et al. MicroRNA signatures in human ovarian cancer. Cancer Res. 2007; 67:8699-8707
-
(2007)
Cancer Res
, vol.67
, pp. 8699-8707
-
-
Iorio, M.V.1
Visone, R.2
Di Leva, G.3
Donati, V.4
Petrocca, F.5
Casalini, P.6
Taccioli, C.7
Volinia, S.8
Liu, C.G.9
Alder, H.10
-
17
-
-
43949136141
-
Potential role of miR-9 and miR-223 in recurrent ovarian cancer
-
Laios A, O'Toole S, Flavin R, Martin C, Kelly L, Ring M, Finn SP, Barrett C, Loda M, Gleeson N, D'Arcy T, McGuinness E, Sheils O, et al. Potential role of miR-9 and miR-223 in recurrent ovarian cancer. Mol Cancer. 2008; 7:35
-
(2008)
Mol Cancer
, vol.7
, pp. 35
-
-
Laios, A.1
O'Toole, S.2
Flavin, R.3
Martin, C.4
Kelly, L.5
Ring, M.6
Finn, S.P.7
Barrett, C.8
Loda, M.9
Gleeson, N.10
D'Arcy, T.11
McGuinness, E.12
Sheils, O.13
-
18
-
-
50849137458
-
MicroRNA expression profiles in serous ovarian carcinoma
-
Nam EJ, Yoon H, Kim SW, Kim H, Kim YT, Kim JH, Kim JW, Kim S. MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res. 2008; 14:2690-2695
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2690-2695
-
-
Nam, E.J.1
Yoon, H.2
Kim, S.W.3
Kim, H.4
Kim, Y.T.5
Kim, J.H.6
Kim, J.W.7
Kim, S.8
-
19
-
-
84874823707
-
Identification of ovarian cancer metastatic miRNAs
-
Vang S, Wu HT, Fischer A, Miller DH, MacLaughlan S, Douglass E, Comisar L, Steinhoff M, Collins C, Smith PJ, Brard L, Brodsky AS. Identification of ovarian cancer metastatic miRNAs. PLoS One. 2013; 8:e58226
-
(2013)
PLoS One
, vol.8
-
-
Vang, S.1
Wu, H.T.2
Fischer, A.3
Miller, D.H.4
MacLaughlan, S.5
Douglass, E.6
Comisar, L.7
Steinhoff, M.8
Collins, C.9
Smith, P.J.10
Brard, L.11
Brodsky, A.S.12
-
20
-
-
33750318273
-
A guide through present computational approaches for the identification of mammalian microRNA targets
-
Sethupathy P, Megraw M, Hatzigeorgiou AG. A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods. 2006; 3:881-886
-
(2006)
Nat Methods
, vol.3
, pp. 881-886
-
-
Sethupathy, P.1
Megraw, M.2
Hatzigeorgiou, A.G.3
-
21
-
-
84875740314
-
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
-
Gao JJ, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun YC, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N. Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal. Sci Signal. 2013; 6(269)
-
(2013)
Sci Signal
, vol.6
, Issue.269
-
-
Gao, J.J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
Sun, Y.C.7
Jacobsen, A.8
Sinha, R.9
Larsson, E.10
Cerami, E.11
Sander, C.12
Schultz, N.13
-
22
-
-
79952818313
-
Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer
-
No JH, Jeon YT, Park IA, Kim YB, Kim JW, Park NH, Kang SB, Han JY, Lim JM, Song YS. Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer. Gynecol Oncol. 2011; 121:8-12
-
(2011)
Gynecol Oncol
, vol.121
, pp. 8-12
-
-
No, J.H.1
Jeon, Y.T.2
Park, I.A.3
Kim, Y.B.4
Kim, J.W.5
Park, N.H.6
Kang, S.B.7
Han, J.Y.8
Lim, J.M.9
Song, Y.S.10
-
23
-
-
70350728790
-
The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells
-
Dahl KDC, Dahl R, Kruichak JN, Hudson LG. The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells. Neoplasia. 2009; 11:1208-U1124
-
(2009)
Neoplasia
, vol.11
-
-
Dahl, K.D.C.1
Dahl, R.2
Kruichak, J.N.3
Hudson, L.G.4
-
24
-
-
84861206450
-
MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)
-
Kim SW, Ramasamy K, Bouamar H, Lin AP, Jiang D, Aguiar RC. MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). Proc Natl Acad Sci U S A. 2012; 109:7865-7870
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 7865-7870
-
-
Kim, S.W.1
Ramasamy, K.2
Bouamar, H.3
Lin, A.P.4
Jiang, D.5
Aguiar, R.C.6
-
25
-
-
72049115805
-
MicroRNA 125a and its regulation of the p53 tumor suppressor gene
-
Zhang YJ, Gao JS, Tang XL, Tucker LD, Quesenberry P, Rigoutsos I, Ramratnam B. MicroRNA 125a and its regulation of the p53 tumor suppressor gene. Febs Lett. 2009; 583:3725-3730
-
(2009)
Febs Lett
, vol.583
, pp. 3725-3730
-
-
Zhang, Y.J.1
Gao, J.S.2
Tang, X.L.3
Tucker, L.D.4
Quesenberry, P.5
Rigoutsos, I.6
Ramratnam, B.7
-
26
-
-
34249946434
-
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
-
Laneve P, Di Marcotullio L, Gioia U, Fiori ME, Ferretti E, Gulino A, Bozzoni I, Caffarelli E. The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. P Natl Acad Sci USA. 2007; 104:7957-7962
-
(2007)
P Natl Acad Sci USA
, vol.104
, pp. 7957-7962
-
-
Laneve, P.1
Di Marcotullio, L.2
Gioia, U.3
Fiori, M.E.4
Ferretti, E.5
Gulino, A.6
Bozzoni, I.7
Caffarelli, E.8
-
27
-
-
77955591555
-
MicroRNAs and their target gene networks in breast cancer
-
O'Day E, Lal A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 2010; 12(2):201
-
(2010)
Breast Cancer Res
, vol.12
, Issue.2
, pp. 201
-
-
O'Day, E.1
Lal, A.2
-
28
-
-
27144475302
-
Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
-
Wu LG, Belasco JG. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol Cell Biol. 2005; 25:9198-9208
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9198-9208
-
-
Wu, L.G.1
Belasco, J.G.2
-
29
-
-
33847738628
-
Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
-
Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem. 2007; 282:1479-1486
-
(2007)
J Biol Chem
, vol.282
, pp. 1479-1486
-
-
Scott, G.K.1
Goga, A.2
Bhaumik, D.3
Berger, C.E.4
Sullivan, C.S.5
Benz, C.C.6
-
30
-
-
77953652759
-
Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells
-
Jiang LL, Huang Q, Zhang SY, Zhang QF, Chang JH, Qiu XS, Wang EH. Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells. Bmc Cancer. 2010; 10:318
-
(2010)
Bmc Cancer
, vol.10
, pp. 318
-
-
Jiang, L.L.1
Huang, Q.2
Zhang, S.Y.3
Zhang, Q.F.4
Chang, J.H.5
Qiu, X.S.6
Wang, E.H.7
-
31
-
-
47149111583
-
Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis
-
Nussbaum T, Samarin J, Ehemann V, Bissinger M, Ryschich E, Khamidianov A, Yu XL, Gretz N, Schirmacher P, Breuhahn K. Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis. Hepatology. 2008; 48:146-156
-
(2008)
Hepatology
, vol.48
, pp. 146-156
-
-
Nussbaum, T.1
Samarin, J.2
Ehemann, V.3
Bissinger, M.4
Ryschich, E.5
Khamidianov, A.6
Yu, X.L.7
Gretz, N.8
Schirmacher, P.9
Breuhahn, K.10
-
32
-
-
84880695313
-
microRNA-125a-3p reduces cell proliferation and migration by targeting Fyn
-
Ninio-Many L, Grossman H, Shomron N, Chuderland D, Shalgi R. microRNA-125a-3p reduces cell proliferation and migration by targeting Fyn. J Cell Sci. 2013; 126:2867-2876
-
(2013)
J Cell Sci
, vol.126
, pp. 2867-2876
-
-
Ninio-Many, L.1
Grossman, H.2
Shomron, N.3
Chuderland, D.4
Shalgi, R.5
-
33
-
-
84874274333
-
Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis
-
He J, Jing Y, Li W, Qian X, Xu Q, Li FS, Liu LZ, Jiang BH, Jiang Y. Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis. PLoS One. 2013; 8:e56647
-
(2013)
PLoS One
, vol.8
-
-
He, J.1
Jing, Y.2
Li, W.3
Qian, X.4
Xu, Q.5
Li, F.S.6
Liu, L.Z.7
Jiang, B.H.8
Jiang, Y.9
-
34
-
-
4644250908
-
The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective
-
Gorgoni B, Gray NK. The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective. Brief Funct Genomic Proteomic. 2004; 3:125-141
-
(2004)
Brief Funct Genomic Proteomic
, vol.3
, pp. 125-141
-
-
Gorgoni, B.1
Gray, N.K.2
-
35
-
-
33846276209
-
4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis
-
Rojo F, Najera L, Lirola J, Jimenez J, Guzman M, Sabadell MD, Baselga J, Cajal SRY. 4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis. Clinical Cancer Research. 2007; 13:81-89
-
(2007)
Clinical Cancer Research
, vol.13
, pp. 81-89
-
-
Rojo, F.1
Najera, L.2
Lirola, J.3
Jimenez, J.4
Guzman, M.5
Sabadell, M.D.6
Baselga, J.7
Cajal, S.R.Y.8
|