메뉴 건너뛰기




Volumn 7, Issue 8, 2016, Pages 8726-8742

MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1

Author keywords

EIF4EBP1; Epithelial ovarian cancer; MicroRNA; MicroRNA 125a; MicroRNA 125b

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 125A; MICRORNA 125B; ONCOPROTEIN; PROTEIN EIF4EBP1; UNCLASSIFIED DRUG; VASCULOTROPIN; EIF4EBP1 PROTEIN, HUMAN; MIRN125 MICRORNA, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA;

EID: 84961644797     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6474     Document Type: Article
Times cited : (52)

References (35)
  • 4
    • 2342489456 scopus 로고    scopus 로고
    • eIF-4E expression and its role in malignancies and metastases
    • De Benedetti A, Graff JR. eIF-4E expression and its role in malignancies and metastases. Oncogene. 2004; 23:3189-3199
    • (2004) Oncogene , vol.23 , pp. 3189-3199
    • De Benedetti, A.1    Graff, J.R.2
  • 6
    • 0035806992 scopus 로고    scopus 로고
    • Cell cycledependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)
    • Heesom KJ, Gampel A, Mellor H, Denton RM. Cell cycledependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1). Curr Biol. 2001; 11:1374-1379
    • (2001) Curr Biol , vol.11 , pp. 1374-1379
    • Heesom, K.J.1    Gampel, A.2    Mellor, H.3    Denton, R.M.4
  • 7
    • 9244228003 scopus 로고    scopus 로고
    • Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
    • Topisirovic I, Ruiz-Gutierrez M, Borden KL. Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res. 2004; 64:8639-8642
    • (2004) Cancer Res , vol.64 , pp. 8639-8642
    • Topisirovic, I.1    Ruiz-Gutierrez, M.2    Borden, K.L.3
  • 9
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010; 466:835-840
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 11
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 13
    • 33746630543 scopus 로고    scopus 로고
    • MicroRNA control of lifespan and metabolism
    • Boehm M, Slack FJ. MicroRNA control of lifespan and metabolism. Cell Cycle. 2006; 5:837-840
    • (2006) Cell Cycle , vol.5 , pp. 837-840
    • Boehm, M.1    Slack, F.J.2
  • 15
    • 77449094218 scopus 로고    scopus 로고
    • MicroRNAs in ovarian carcinomas
    • Dahiya N, Morin PJ. MicroRNAs in ovarian carcinomas. Endocr Relat Cancer. 2010; 17:F77-89
    • (2010) Endocr Relat Cancer , vol.17 , pp. F77-F89
    • Dahiya, N.1    Morin, P.J.2
  • 20
    • 33750318273 scopus 로고    scopus 로고
    • A guide through present computational approaches for the identification of mammalian microRNA targets
    • Sethupathy P, Megraw M, Hatzigeorgiou AG. A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods. 2006; 3:881-886
    • (2006) Nat Methods , vol.3 , pp. 881-886
    • Sethupathy, P.1    Megraw, M.2    Hatzigeorgiou, A.G.3
  • 23
    • 70350728790 scopus 로고    scopus 로고
    • The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells
    • Dahl KDC, Dahl R, Kruichak JN, Hudson LG. The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells. Neoplasia. 2009; 11:1208-U1124
    • (2009) Neoplasia , vol.11
    • Dahl, K.D.C.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 24
    • 84861206450 scopus 로고    scopus 로고
    • MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)
    • Kim SW, Ramasamy K, Bouamar H, Lin AP, Jiang D, Aguiar RC. MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). Proc Natl Acad Sci U S A. 2012; 109:7865-7870
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 7865-7870
    • Kim, S.W.1    Ramasamy, K.2    Bouamar, H.3    Lin, A.P.4    Jiang, D.5    Aguiar, R.C.6
  • 26
    • 34249946434 scopus 로고    scopus 로고
    • The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
    • Laneve P, Di Marcotullio L, Gioia U, Fiori ME, Ferretti E, Gulino A, Bozzoni I, Caffarelli E. The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. P Natl Acad Sci USA. 2007; 104:7957-7962
    • (2007) P Natl Acad Sci USA , vol.104 , pp. 7957-7962
    • Laneve, P.1    Di Marcotullio, L.2    Gioia, U.3    Fiori, M.E.4    Ferretti, E.5    Gulino, A.6    Bozzoni, I.7    Caffarelli, E.8
  • 27
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • O'Day E, Lal A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 2010; 12(2):201
    • (2010) Breast Cancer Res , vol.12 , Issue.2 , pp. 201
    • O'Day, E.1    Lal, A.2
  • 28
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
    • Wu LG, Belasco JG. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol Cell Biol. 2005; 25:9198-9208
    • (2005) Mol Cell Biol , vol.25 , pp. 9198-9208
    • Wu, L.G.1    Belasco, J.G.2
  • 29
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem. 2007; 282:1479-1486
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 30
    • 77953652759 scopus 로고    scopus 로고
    • Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells
    • Jiang LL, Huang Q, Zhang SY, Zhang QF, Chang JH, Qiu XS, Wang EH. Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells. Bmc Cancer. 2010; 10:318
    • (2010) Bmc Cancer , vol.10 , pp. 318
    • Jiang, L.L.1    Huang, Q.2    Zhang, S.Y.3    Zhang, Q.F.4    Chang, J.H.5    Qiu, X.S.6    Wang, E.H.7
  • 32
    • 84880695313 scopus 로고    scopus 로고
    • microRNA-125a-3p reduces cell proliferation and migration by targeting Fyn
    • Ninio-Many L, Grossman H, Shomron N, Chuderland D, Shalgi R. microRNA-125a-3p reduces cell proliferation and migration by targeting Fyn. J Cell Sci. 2013; 126:2867-2876
    • (2013) J Cell Sci , vol.126 , pp. 2867-2876
    • Ninio-Many, L.1    Grossman, H.2    Shomron, N.3    Chuderland, D.4    Shalgi, R.5
  • 34
    • 4644250908 scopus 로고    scopus 로고
    • The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective
    • Gorgoni B, Gray NK. The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective. Brief Funct Genomic Proteomic. 2004; 3:125-141
    • (2004) Brief Funct Genomic Proteomic , vol.3 , pp. 125-141
    • Gorgoni, B.1    Gray, N.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.