Prevalence and risk factors of postoperative delirium in elderly hip fracture patients

Journal of International Medical Research

Volumn 44, Issue 2, 2016, Pages 317-327

  Guo, Yong ^a,b   Jia, Peiyu ^a   Zhang, Junfeng ^a   Wang, Xuemin ^a   Jiang, Hong ^b   Jiang, Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

elderly patients; hip fracture; Postoperative delirium; risk factors

Indexed keywords

ALBUMIN; BILIRUBIN; C REACTIVE PROTEIN; GLUCOSE BLOOD LEVEL; INTRAVENOUS ANESTHETIC AGENT; MIDAZOLAM; SUFENTANIL;

AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CLINICAL LABORATORY; COMORBIDITY; CONFUSION; DISEASE ASSOCIATION; ERYTHROCYTE TRANSFUSION; FEMALE; GENERAL ANESTHESIA; GERIATRIC PATIENT; GLUCOSE BLOOD LEVEL; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; OPERATION DURATION; POSTOPERATIVE DELIRIUM; POSTOPERATIVE PERIOD; PREVALENCE; PROSPECTIVE STUDY; RISK FACTOR; TOTAL HIP PROSTHESIS; AGE; BLOOD; BLOOD TRANSFUSION; EMERGENCE DELIRIUM; HIP FRACTURES; HIP REPLACEMENT; INJURIES; METABOLISM; MULTIVARIATE ANALYSIS; PATHOLOGY; PATHOPHYSIOLOGY; PELVIC GIRDLE; PROCEDURES; STATISTICAL MODEL; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANESTHESIA, GENERAL; ANESTHETICS, INTRAVENOUS; ARTHROPLASTY, REPLACEMENT, HIP; BILIRUBIN; BLOOD GLUCOSE; BLOOD TRANSFUSION; C-REACTIVE PROTEIN; EMERGENCE DELIRIUM; FEMALE; HIP FRACTURES; HUMANS; LOGISTIC MODELS; MALE; MIDAZOLAM; MULTIVARIATE ANALYSIS; PELVIC BONES; PROSPECTIVE STUDIES; RISK FACTORS; SUFENTANIL;

EID: 84961641138     PISSN: 03000605     EISSN: 14732300     Source Type: Journal    
DOI: 10.1177/0300060515624936     Document Type: Article

References (41)

1. G.L.FricchioneS.H.NejadJ.A.Esses. Postoperative delirium. Am J Psychiatry2008; 165: 803–812.
2. N.Y.WangA.HiraoF.Sieber. Association between intraoperative blood pressure and postoperative delirium in elderly hip fracture patients. PLoS One2015; 10: e0123892–e0123892.
3. M.G.ZywielR.T.HurleyA.V.Perruccio. Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture. J Bone Joint Surg Am2015; 97: 829–836.
4. Y.Skrobik. Delirium prevention and treatment. Anesthesiol Clin2011; 29: 721–727.
5. J.R.Maldonado. Neuropathogenesis of delirium: review of current etiologic theories and common pathways. Am J Geriatr Psychiatry2013; 21: 1190–1222.
6. Y.L.ChenH.C.LinK.H.Lin. Low hemoglobin level is associated with the development of delirium after hepatectomy for hepatocellular carcinoma patients. PLoS One2015; 10: e0119199–e0119199.
7. S.TaiL.XuL.Zhang. Preoperative risk factors of postoperative delirium after transurethral prostatectomy for benign prostatic hyperplasia. Int J Clin Exp Med2015; 8: 4569–4574.
8. C.J.JankowskiM.R.TrenerryD.J.Cook. Cognitive and functional predictors and sequelae of postoperative delirium in elderly patients undergoing elective joint arthroplasty. Anesth Analg2011; 112: 1186–1193.
9. D.WesthoffJ.WitloxL.Koenderman. Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients. J Neuroinflammation2013; 10: 122–122.
10. American Society of Anesthesiologists. ASA Physical Status Classification System, www.asahq.org/resources/clinical-information/asa-physical-status-classification-system (accessed 15 October 2014)
11. M.F.FolsteinS.E.FolsteinP.R.McHugh. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res1975; 12: 189–198.
12. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864–874
13. T.A.WidigerA.J.FrancesH.A.Pincus. Diagnostic and statistical manual of mental disorders: DSM-IV, 4th ed. Washington, DC: American Psychiatric Association, 2000.
14. S.K.InouyeC.H.van DyckC.A.Alessi. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med1990; 113: 941–948.
15. W.Y.ZhangW.L.WuJ.J.Gu. Risk factors for postoperative delirium in patients after coronary artery bypass grafting: A prospective cohort study. J Crit Care2015; 30: 606–612.
16. S.FreterM.DunbarK.Koller. Risk of pre-and post-operative delirium and the Delirium Elderly At Risk (DEAR) tool in hip fracture patients. Can Geriatr J2015; 4: 212–216.
17. S.M.de CastroÇ.ÜnlüJ.B.Tuynman. Incidence and risk factors of delirium in the elderly general surgical patient. Am J Surg2014; 208: 26–32.
18. D.RingaitienėD.GineitytėV.Vicka. Impact of malnutrition on postoperative delirium development after on pump coronary artery bypass grafting. J Cardiothorac Surg2015; 10: 74–74.
19. J.W.RaatsW.A.van EijsdenR.M.Crolla. Risk factors and outcomes for postoperative delirium after major surgery in elderly patients. PLoS One2015; 10: e0136071–e0136071.
20. B.D.RobertsonT.J.Robertson. Postoperative delirium after hip fracture. J Bone Joint Surg Am2006; 88: 2060–2068.
21. J.H.SilversteinM.TimbergerD.L.Reich. Central nervous system dysfunction after noncardiac surgery and anesthesia in the elderly. Anesthesiology2007; 106: 622–628.
22. I.ChermeshJ.HajosT.Mashiach. Malnutrition in cardiac surgery: food for thought. Eur J Prev Cardiol2014; 21: 475–483.
23. L.M.van VenrooijR.de VosE.Zijlstra. The impact of low preoperative fat-free body mass on infections and length of stay after cardiac surgery: a prospective cohort study. J Thorac Cardiovasc Surg2011; 142: 1263–1269.
24. C.S.ChuC.K.LiangM.Y.Chou. Short-Form Mini Nutritional Assessment as a useful method of predicting the development of postoperative delirium in elderly patients undergoing orthopedic surgery. Gen Hosp Psychiatry2016; 38: 15–20.
25. S.OtomoK.MaekawaT.Goto. Pre-existing cerebral infarcts as a risk factor for delirium after coronary artery bypass graft surgery. Interact Cardiovasc Thorac Surg2013; 17: 799–804.
26. M.F.LugerS.MüllerC.Kammerlander. Predictors of postoperative cognitive decline in very old patients with hip fracture: a retrospective analysis. Geriatr Orthop Surg Rehabil2014; 5: 165–172.
27. D.S.Knopman. Cerebrovascular disease and dementia. Br J Radiol2007; 80: S121–S127.
28. H.OmiyaK.YoshitaniN.Yamada. Preoperative brain magnetic resonance imaging and postoperative delirium after off-pump coronary artery bypass grafting: a prospective cohort study. Can J Anaesth2015; 62: 595–602.
29. L.J.KrzychM.T.WybraniecI.Krupka-Matuszczyk. Complex assessment of the incidence and risk factors of delirium in a large cohort of cardiac surgery patients: a single-center 6-year experience. Biomed Res Int2013; 2013: 835850–835850.
30. L.J.KrzychM.T.WybraniecI.Krupka-Matuszczyk. Detailed insight into the impact of postoperative neuropsychiatric complications on mortality in a cohort of cardiac surgery subjects: a 23,000-patient-year analysis. J Cardiothorac Vasc Anesth2014; 28: 448–457.
31. M.O.OzyurtkanB.YildizeliK.Kuşçu. Postoperative psychiatric disorders in general thoracic surgery: incidence, risk factors and outcomes. Eur J Cardiothorac Surg2010; 37: 1152–1157.
32. G.Y.GandhiG.A.NuttallM.D.Abel. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clin Proc2005; 80: 862–866.
33. L.SaagerA.E.DuncanJ.P.Yared. Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery. Anesthesiology2015; 122: 1214–1223.
34. J.CerejeiraP.BatistaV.Nogueira. Low preoperative plasma cholinesterase activity as a risk marker of postoperative delirium in elderly patients. Age Ageing2011; 40: 621–626.
35. Y.YoshimuraS.KuboK.Shirata. Risk factors for postoperative delirium after liver resection for hepatocellular carcinoma. World J Surg2004; 28: 982–986.
36. J.CerejeiraP.BatistaV.Nogueira. The stress response to surgery and postoperative delirium: evidence of hypothalamic-pituitary-adrenal axis hyperresponsiveness and decreased suppression of the GH/IGF-1 Axis. J Geriatr Psychiatry Neurol2013; 26: 185–194.
37. J.KazmierskiA.BanysJ.Latek. Mild cognitive impairment with associated inflammatory and cortisol alterations as independent risk factor for postoperative delirium. Dement Geriatr Cogn Disord2014; 38: 65–78.
38. Y.BelooseskyD.HendelA.Weiss. Cytokines and C-reactive protein production in hip-fracture-operated elderly patients. J Gerontol A Biol Sci Med Sci2007; 62: 420–426.
39. I.L.Campbell. Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology. Brain Res Brain Res Rev1998; 26: 327–336.
40. R.A.PolB.L.van LeeuwenG.J.Izaks. C-reactive protein predicts postoperative delirium following vascular surgery. Ann Vasc Surg2014; 28: 1923–1930.
41. T.HasegawaI.SaitoD.Takeda. Risk factors associated with postoperative delirium after surgery for oral cancer. J Craniomaxillofac Surg2015; 43: 1094–1098.