Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells

Oncotarget

Volumn 7, Issue 8, 2016, Pages 9561-9575

  Palanca Wessels, Maria C ^a,b   Booth, Garrett C ^a   Convertine, Anthony J ^c   Lundy, Brittany B ^c   Berguig, Geoffrey Y ^c   Press, Michael F ^d   Stayton, Patrick S ^c   Press, Oliver W ^a,c  

^a USA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c University of Washington   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Breast cancer; HER2 antibody; Ovarian cancer; siRNA; Targeted antibody delivery

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; NANOCARRIER; SMALL INTERFERING RNA; TRASTUZUMAB; ANTINEOPLASTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; FEMALE; GENE EXPRESSION; GENE REPRESSION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OVARY CANCER; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR XENOGRAFT; ANIMAL; BREAST NEOPLASMS; DRUG SCREENING; GENE THERAPY; GENETICS; HUMAN; IMMUNOLOGY; NUDE MOUSE; OVARIAN NEOPLASMS; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENETIC THERAPY; HUMANS; MICE; MICE, NUDE; OVARIAN NEOPLASMS; RECEPTOR, ERBB-2; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRASTUZUMAB; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84961631525     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7076     Document Type: Article

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