메뉴 건너뛰기




Volumn 16, Issue 4, 2016, Pages 432-439

miRNA-101 suppresses epithelial-to-mesenchymal transition by targeting HMGA2 in pancreatic cancer cells

Author keywords

Epithelial to mesenchymal transition; HMGA2; MiR 101; Pancreatic cancer

Indexed keywords

CA 19-9 ANTIGEN; HIGH MOBILITY GROUP A2 PROTEIN; MICRORNA 101; MICRORNA; MIRN101 MICRORNA, HUMAN;

EID: 84961603788     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/1871520615666150507122142     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 84871183823 scopus 로고    scopus 로고
    • Demographics and epidemiology of pancreatic cancer
    • Yeo, T.P.; Lowenfels, A.B. Demographics and epidemiology of pancreatic cancer. Cancer J., 2012, 18, 477-484.
    • (2012) Cancer J. , vol.18 , pp. 477-484
    • Yeo, T.P.1    Lowenfels, A.B.2
  • 2
    • 84893401267 scopus 로고    scopus 로고
    • Pancreatic cancer incidence and mortality patterns in china, 2009. Asi. Pac
    • Chen, W.Q.; Liang, D.; Zhang, S.W.; Zheng, R.S.; He, Y.T., Pancreatic cancer incidence and mortality patterns in china, 2009. Asi. Pac. J. Cancer Prev., 2013, 14, 7321-7324.
    • (2013) J. Cancer Prev. , vol.14 , pp. 7321-7324
    • Chen, W.Q.1    Liang, D.2    Zhang, S.W.3    Zheng, R.S.4    He, Y.T.5
  • 3
    • 84889664298 scopus 로고    scopus 로고
    • Systematic review of risk factors for metastasis to para-aortic lymph nodes in gastric cancer. Surg
    • Junfeng, Z.; Yingxue, H.; Peiwu, Y. Systematic review of risk factors for metastasis to para-aortic lymph nodes in gastric cancer. Surg. Oncol., 2013, 22, 210-216.
    • (2013) Oncol. , vol.22 , pp. 210-216
    • Junfeng, Z.1    Yingxue, H.2    Peiwu, Y.3
  • 4
    • 84886096423 scopus 로고    scopus 로고
    • The prognostic impact of occult lymph node metastasis in node-negative gastric cancer, a systematic review and meta-analysis
    • Huang, J.Y.; Xu, Y.Y.; Li, M.; Sun, Z.; Zhu, Z.; Song, Y.X.; Miao, Z.F.; Wu, J.H.; Xu, H.M. The prognostic impact of occult lymph node metastasis in node-negative gastric cancer, a systematic review and meta-analysis. Ann. Surg. Oncol., 2013, 20, 3927-3934.
    • (2013) Ann. Surg. Oncol. , vol.20 , pp. 3927-3934
    • Huang, J.Y.1    Xu, Y.Y.2    Li, M.3    Sun, Z.4    Zhu, Z.5    Song, Y.X.6    Miao, Z.F.7    Wu, J.H.8    Xu, H.M.9
  • 5
    • 84870806564 scopus 로고    scopus 로고
    • Where are the cancer stem cells?
    • Brabletz, T. EMT and MET in metastasis: Where are the cancer stem cells? Cancer Cell, 2012, 22, 699-701.
    • (2012) Cancer Cell , vol.22 , pp. 699-701
    • Brabletz, T.1
  • 6
    • 84884484146 scopus 로고    scopus 로고
    • New perspective of vasculogenic mimicry: EMT and cancer stem cells (Review). Oncol
    • Fan, Y.L.; Zheng, M.; Tang, Y.L.; Liang, X. H. A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review). Oncol. Lett., 2013, 6, 1174-1180.
    • (2013) Lett. , vol.6 , pp. 1174-1180
    • Fan, Y.L.1    Zheng, M.2    Tang, Y.L.3    Liang, X.4
  • 7
    • 79954999152 scopus 로고    scopus 로고
    • Signalling pathways involved in endocrine resistance in breast cancer and associations with epithelial to mesenchymal transition (Review). Int
    • Al Saleh, S.; Sharaf, L.H.; Luqmani, Y.A., Signalling pathways involved in endocrine resistance in breast cancer and associations with epithelial to mesenchymal transition (Review). Int. J. Oncol., 2011, 38, 1197-1217.
    • (2011) J. Oncol. , vol.38 , pp. 1197-1217
    • Al Saleh, S.1    Sharaf, L.H.2    Luqmani, Y.A.3
  • 8
    • 84920120629 scopus 로고    scopus 로고
    • Clinical significance of epithelial-mesenchymal transition. Clin. Transl
    • Steinestel, K.; Eder, S.; Schrader, A.J.; Steinestel, J. Clinical significance of epithelial-mesenchymal transition. Clin. Transl. Med., 2014, 3, 17.
    • (2014) Med. , vol.3 , pp. 17
    • Steinestel, K.1    Eder, S.2    Schrader, A.J.3    Steinestel, J.4
  • 9
    • 84928888544 scopus 로고    scopus 로고
    • MicroRNAs regulate the epithelial to mesenchymal transition (EMT) in cancer progression
    • Hu, Y.; Tang, H., MicroRNAs regulate the epithelial to mesenchymal transition (EMT) in cancer progression. Microrna, 2014, 3(2),108-117.
    • (2014) Microrna , vol.3 , Issue.2 , pp. 108-117
    • Hu, Y.1    Tang, H.2
  • 10
    • 84900505196 scopus 로고    scopus 로고
    • Illustrating the interplay between the extracellular matrix and microRNAs
    • Piccinini, A.M.; Midwood, K.S., Illustrating the interplay between the extracellular matrix and microRNAs. Int. J. Exp. Pathol., 2014, 95, 158-180.
    • (2014) Int. J. Exp. Pathol. , vol.95 , pp. 158-180
    • Piccinini, A.M.1    Midwood, K.S.2
  • 11
    • 84898020906 scopus 로고    scopus 로고
    • MicroRNA theragnostics for the clinical management of multiple myeloma
    • Ahmad, N.; Haider, S.; Jagannathan, S.; Anaissie, E.; Driscoll, J.J. MicroRNA theragnostics for the clinical management of multiple myeloma. Leukemia, 2014, 28, 732-738.
    • (2014) Leukemia , vol.28 , pp. 732-738
    • Ahmad, N.1    Haider, S.2    Jagannathan, S.3    Anaissie, E.4    Driscoll, J.J.5
  • 13
    • 84873488599 scopus 로고    scopus 로고
    • Down-regulation of the miRNA- 200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression
    • Paterson, E.L.; Kazenwadel, J.; Bert, A.G.; Khew-Goodall, Y.; Ruszkiewicz, A.; Goodall, G.J. Down-regulation of the miRNA- 200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression. Neoplasia, 2013, 15, 180-191.
    • (2013) Neoplasia , vol.15 , pp. 180-191
    • Paterson, E.L.1    Kazenwadel, J.2    Bert, A.G.3    Khew-Goodall, Y.4    Ruszkiewicz, A.5    Goodall, G.J.6
  • 14
    • 84868250570 scopus 로고    scopus 로고
    • Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR- 101, miR-106a and miR-145 in colorectal cancer
    • Schee, K.; Boye, K.; Abrahamsen, T.W.; Fodstad, O.; Flatmark, K. Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR- 101, miR-106a and miR-145 in colorectal cancer. BMC Cancer, 2012, 12, 505.
    • (2012) BMC Cancer , vol.12 , pp. 505
    • Schee, K.1    Boye, K.2    Abrahamsen, T.W.3    Fodstad, O.4    Flatmark, K.5
  • 16
    • 84872675104 scopus 로고    scopus 로고
    • MiR-101 and Mcl-1 in non-small-cell lung cancer, expression profile and clinical significance. Med
    • Luo, L.; Zhang, T.; Liu, H.; Lv, T.; Yuan, D.; Yao, Y.; Lv, Y.; Song, Y. MiR-101 and Mcl-1 in non-small-cell lung cancer, expression profile and clinical significance. Med. Oncol., 2012, 29, 1681-1686.
    • (2012) Oncol. , vol.29 , pp. 1681-1686
    • Luo, L.1    Zhang, T.2    Liu, H.3    Lv, T.4    Yuan, D.5    Yao, Y.6    Lv, Y.7    Song, Y.8
  • 17
    • 84894097845 scopus 로고    scopus 로고
    • Roles of MiR-101 and its target gene Cox-2 in early diagnosis of cervical cancer in Uygur women
    • Lin, C.; Huang, F.; Zhang, Y.J.; Tuokan, T.; Kuerban, G., Roles of MiR-101 and its target gene Cox-2 in early diagnosis of cervical cancer in Uygur women. Asi. Pac. J. Cancer Prev., 2014, 15, 45-48.
    • (2014) Asi. Pac. J. Cancer Prev. , vol.15 , pp. 45-48
    • Lin, C.1    Huang, F.2    Zhang, Y.J.3    Tuokan, T.4    Kuerban, G.5
  • 18
    • 84876211114 scopus 로고    scopus 로고
    • MiR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
    • Xu, Y.; An, Y.; Wang, Y.; Zhang, C.; Zhang, H.; Huang, C.; Jiang, H.; Wang, X.; Li, X. miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol. Rep., 2013, 29, 2019-2024.
    • (2013) Oncol. Rep. , vol.29 , pp. 2019-2024
    • Xu, Y.1    An, Y.2    Wang, Y.3    Zhang, C.4    Zhang, H.5    Huang, C.6    Jiang, H.7    Wang, X.8    Li, X.9
  • 20
    • 84883154324 scopus 로고    scopus 로고
    • Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-tomesenchymal transition in an orthotopic model
    • Boreddy, S.R.; Srivastava, S.K. Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-tomesenchymal transition in an orthotopic model. Oncogene, 2013, 32, 3980-3991.
    • (2013) Oncogene , vol.32 , pp. 3980-3991
    • Boreddy, S.R.1    Srivastava, S.K.2
  • 21
    • 77958451128 scopus 로고    scopus 로고
    • MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells
    • Ponnusamy, M.P.; Lakshmanan, I.; Jain, M.; Das, S.; Chakraborty, S.; Dey, P.; Batra, S.K. MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells. Oncogene, 2010, 29, 5741-5754.
    • (2010) Oncogene , vol.29 , pp. 5741-5754
    • Ponnusamy, M.P.1    Lakshmanan, I.2    Jain, M.3    Das, S.4    Chakraborty, S.5    Dey, P.6    Batra, S.K.7
  • 22
    • 77950621871 scopus 로고    scopus 로고
    • Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines
    • Chen, C.L.; Chou, K.J.; Lee, P.T.; Chen, Y.S.; Chang, T.Y.; Hsu, C.Y.; Huang, W.C.; Chung, H.M.; Fang, H.C., Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines. Exp. Cell Res., 2010, 316, 1109-1118.
    • (2010) Exp. Cell Res. , vol.316 , pp. 1109-1118
    • Chen, C.L.1    Chou, K.J.2    Lee, P.T.3    Chen, Y.S.4    Chang, T.Y.5    Hsu, C.Y.6    Huang, W.C.7    Chung, H.M.8    Fang, H.C.9
  • 23
    • 80051793013 scopus 로고    scopus 로고
    • MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI- 1. Mol
    • Dong, P.; Kaneuchi, M.; Watari, H.; Hamada, J.; Sudo, S.; Ju, J.; Sakuragi, N. MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI- 1. Mol. Cancer, 2011, 10, 99.
    • (2011) Cancer , vol.10 , pp. 99
    • Dong, P.1    Kaneuchi, M.2    Watari, H.3    Hamada, J.4    Sudo, S.5    Ju, J.6    Sakuragi, N.7
  • 24
    • 84892828470 scopus 로고    scopus 로고
    • MicroRNA-200a and -200b mediated hepatocellular carcinoma cell migration through the epithelial to mesenchymal transition markers. Ann. Surg
    • Hung, C.S.; Liu, H.H.; Liu, J.J.; Yeh, C.T.; Chang, T.C.; Wu, C.H.; Ho, Y.S.; Wei, P.L.; Chang, Y.J., MicroRNA-200a and -200b mediated hepatocellular carcinoma cell migration through the epithelial to mesenchymal transition markers. Ann. Surg. Oncol., 2013, 20 Suppl 3, S360-368.
    • Oncol., 2013, 20 Suppl , vol.3
    • Hung, C.S.1    Liu, H.H.2    Liu, J.J.3    Yeh, C.T.4    Chang, T.C.5    Wu, C.H.6    Ho, Y.S.7    Wei, P.L.8    Chang, Y.J.9
  • 25
    • 84899631930 scopus 로고    scopus 로고
    • Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives. Cancer Manag
    • Diaz-Lopez, A.; Moreno-Bueno, G.; Cano, A. Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives. Cancer Manag. Res., 2014, 6, 205-216.
    • (2014) Res. , vol.6 , pp. 205-216
    • Diaz-Lopez, A.1    Moreno-Bueno, G.2    Cano, A.3
  • 26
    • 84893729970 scopus 로고    scopus 로고
    • MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN. Dig. Dis
    • Zhang, G.; Zhou, H.; Xiao, H.; Liu, Z.; Tian, H.; Zhou, T. MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN. Dig. Dis. Sci., 2014, 59, 98-107.
    • (2014) Sci. , vol.59 , pp. 98-107
    • Zhang, G.1    Zhou, H.2    Xiao, H.3    Liu, Z.4    Tian, H.5    Zhou, T.6
  • 27
    • 84905401527 scopus 로고    scopus 로고
    • MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling
    • Zhang, J.P.; Zeng, C.; Xu, L.; Gong, J.; Fang, J.H.; Zhuang, S.M. MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene, 2014, 33, 4069-4076.
    • (2014) Oncogene , vol.33 , pp. 4069-4076
    • Zhang, J.P.1    Zeng, C.2    Xu, L.3    Gong, J.4    Fang, J.H.5    Zhuang, S.M.6
  • 29
    • 84908005389 scopus 로고    scopus 로고
    • HMGA2 induces transcription factor Slug expression to promote epithelialto- mesenchymal transition and contributes to colon cancer progression
    • Li, Y.; Zhao, Z.; Xu, C.; Zhou, Z.; Zhu, Z.; You, T. HMGA2 induces transcription factor Slug expression to promote epithelialto- mesenchymal transition and contributes to colon cancer progression. Cancer Lett., 2014, 355, 130-140.
    • (2014) Cancer Lett. , vol.355 , pp. 130-140
    • Li, Y.1    Zhao, Z.2    Xu, C.3    Zhou, Z.4    Zhu, Z.5    You, T.6
  • 30
    • 77955336023 scopus 로고    scopus 로고
    • HMGA2: A pituitary tumour subtype-specific oncogene? Mol
    • Fedele, M.; Palmieri, D.; Fusco, A. HMGA2: A pituitary tumour subtype-specific oncogene? Mol. Cell Endocrinol., 2010, 326, 19-24.
    • (2010) Cell Endocrinol. , vol.326 , pp. 19-24
    • Fedele, M.1    Palmieri, D.2    Fusco, A.3
  • 31
    • 74549142329 scopus 로고    scopus 로고
    • In vivo modulation of HMGA2 expression. Biochim. Biophys
    • Ashar, H. R.; Chouinard, R.A.; Dokur, M.; Chada, K., In vivo modulation of HMGA2 expression. Biochim. Biophys. Acta, 2010, 1799, 55-61.
    • (2010) Acta , vol.1799 , pp. 55-61
    • Ashar, H.R.1    Chouinard, R.A.2    Dokur, M.3    Chada, K.4
  • 32
    • 84876668099 scopus 로고    scopus 로고
    • HMGA2 elicits EMT by activating the Wnt/beta-catenin pathway in gastric cancer. Dig. Dis
    • Zha, L.; Zhang, J.; Tang, W.; Zhang, N.; He, M.; Guo, Y.; Wang, Z., HMGA2 elicits EMT by activating the Wnt/beta-catenin pathway in gastric cancer. Dig. Dis. Sci., 2013, 58, 724-733.
    • (2013) Sci. , vol.58 , pp. 724-733
    • Zha, L.1    Zhang, J.2    Tang, W.3    Zhang, N.4    He, M.5    Guo, Y.6    Wang, Z.7
  • 33
    • 84870722925 scopus 로고    scopus 로고
    • The expression of the high-mobility group A2 protein in colorectal cancer and surrounding fibroblasts is linked to tumor invasiveness. Hum
    • Rizzi, C.; Cataldi, P.; Iop, A.; Isola, M.; Sgarra, R.; Manfioletti, G.; Giancotti, V. The expression of the high-mobility group A2 protein in colorectal cancer and surrounding fibroblasts is linked to tumor invasiveness. Hum. Pathol., 2013, 44, 122-132.
    • (2013) Pathol. , vol.44 , pp. 122-132
    • Rizzi, C.1    Cataldi, P.2    Iop, A.3    Isola, M.4    Sgarra, R.5    Manfioletti, G.6    Giancotti, V.7
  • 34
    • 24644468196 scopus 로고    scopus 로고
    • HMGA2 is associated with invasiveness but not a suitable marker for the detection of circulating tumor cells in breast cancer. Oncol
    • Fabjani, G.; Tong, D.; Wolf, A.; Roka, S.; Leodolter, S.; Hoecker, P.; Fischer, M.B.; Jakesz, R.; Zeillinger, R., HMGA2 is associated with invasiveness but not a suitable marker for the detection of circulating tumor cells in breast cancer. Oncol. Rep., 2005, 14, 737-741.
    • (2005) Rep. , vol.14 , pp. 737-741
    • Fabjani, G.1    Tong, D.2    Wolf, A.3    Roka, S.4    Leodolter, S.5    Hoecker, P.6    Fischer, M.B.7    Jakesz, R.8    Zeillinger, R.9
  • 35
    • 84874442280 scopus 로고    scopus 로고
    • HMGA2 induces epithelial-tomesenchymal transition in human hepatocellular carcinoma cells. Oncol
    • Luo, Y.; Li, W.; Liao, H. HMGA2 induces epithelial-tomesenchymal transition in human hepatocellular carcinoma cells. Oncol. Lett., 2013, 5, 1353-1356.
    • (2013) Lett. , vol.5 , pp. 1353-1356
    • Luo, Y.1    Li, W.2    Liao, H.3
  • 36
    • 84921934369 scopus 로고    scopus 로고
    • HMGA2 is down-regulated by microRNA let-7 and associated with epithelial-mesenchymal transition in oesophageal squamous cell carcinomas of Kazakhs
    • Liu, Q.; Zheng, S.; Gao, X.; Lu, M.; Sheyhidin, I.; Lu, X. HMGA2 is down-regulated by microRNA let-7 and associated with epithelial-mesenchymal transition in oesophageal squamous cell carcinomas of Kazakhs. Histopathology, 2014, 65, 408-417.
    • (2014) Histopathology , vol.65 , pp. 408-417
    • Liu, Q.1    Zheng, S.2    Gao, X.3    Lu, M.4    Sheyhidin, I.5    Lu, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.