Outcome and Impact of Aortic Valve Replacement in Patients with Preserved LVEF and Low-Gradient Aortic Stenosis

Journal of the American College of Cardiology

Volumn 66, Issue 23, 2015, Pages 2594-2603

  Dayan, Victor ^a   Vignolo, Gustavo ^a   Magne, Julien ^b   Clavel, Marie Annick ^c   Mohty, Dania ^b   Pibarot, Philippe ^c  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b LIMOGES UNIVERSITY HOSPITAL   (France)

^c LAVAL UNIVERSITY   (Canada)

Author keywords

aortic valve replacement; low gradient aortic stenosis; paradoxical flow aortic stenosis

Indexed keywords

AORTA STENOSIS; AORTA VALVE REPLACEMENT; ARTICLE; COMPARATIVE STUDY; DISEASE SEVERITY; HEART LEFT VENTRICLE EJECTION FRACTION; HEART STROKE VOLUME; HUMAN; MORTALITY; OUTCOME ASSESSMENT; PRESERVED LEFT VENTRICULAR EJECTION FRACTION; PRIORITY JOURNAL; SURVIVAL; ADVERSE EFFECTS; AORTA VALVE; AORTIC VALVE STENOSIS; ECHOCARDIOGRAPHY; ECHOGRAPHY; HEART LEFT VENTRICLE FUNCTION; HEART VALVE PROSTHESIS; HEART VALVE REPLACEMENT; META ANALYSIS; PATHOPHYSIOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

AORTIC VALVE; AORTIC VALVE STENOSIS; ECHOCARDIOGRAPHY; HEART VALVE PROSTHESIS; HEART VALVE PROSTHESIS IMPLANTATION; HUMANS; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STROKE VOLUME; SURVIVAL ANALYSIS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 84961588451     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.09.076     Document Type: Article

References (35)

1. R.O. Bonow, B.A. Carabello, C. Kanu, and et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons J Am Coll Cardiol 48 2006 598 675
2. A. Vahanian, O. Alfieri, F. Andreotti, and et al. Guidelines on the management of valvular heart disease (version 2012). Joint task force on the management of valvular heart disease of the European Society of Cardiology (ESC); European Association for Cardio-Thoracic Surgery (EACTS) Eur Heart J 33 2012 2451 2496
3. J. Minners, M. Allgeier, C. Gohlke-Baerwolf, R.P. Kienzle, F.J. Neumann, and N. Jander Inconsistent grading of aortic valve stenosis by current guidelines: haemodynamic studies in patients with apparently normal left ventricular function Heart 96 2010 1463 1468
4. Z. Hachicha, J.G. Dumesnil, P. Bogaty, and P. Pibarot Paradoxical low flow, low gradient severe aortic stenosis despite preserved ejection fraction is associated with higher afterload and reduced survival Circulation 115 2007 2856 2864
5. R.A. Nishimura, C.M. Otto, R.O. Bonow, and et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: Executive summary. A report of the American College of Cardiology/American Heart Association task force on practice guidelines J Am Coll Cardiol 63 2014 2438 2488
6. M.A. Clavel, J.G. Dumesnil, R. Capoulade, P. Mathieu, M. Senechal, and P. Pibarot Outcome of patients with aortic stenosis, small valve area and low-flow, low-gradient despite preserved left ventricular ejection fraction J Am Coll Cardiol 60 2012 1259 1267
7. A. Ozkan, R. Hachamovitch, S.R. Kapadia, E.M. Tuzcu, and T.H. Marwick Impact of aortic valve replacement on outcome of symptomatic patients with severe aortic stenosis with low gradient and preserved left ventricular ejection fraction Circulation 128 2013 622 631
8. P. Mehrotra, K. Jansen, A.W. Flynn, and et al. Differential left ventricular remodelling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis Eur Heart J 34 2013 1906 1914
9. G. Melis, G. Frontera, G. Caldentey, and et al. Systolic volume index by Doppler echocardiography is an useful marker for stratification and prognostic evaluation in patients with severe aortic stenosis and preserved ejection fraction Rev Esp Cardiol 66 2013 261 268
10. F. Maes, J. Boulif, S. Pierard, and et al. Natural history of paradoxical low gradient "severe" aortic stenosis Circ Cardiovasc Imaging 7 2014 714 722
11. C. Tribouilloy, D. Rusinaru, S. Marechaux, and et al. Low-gradient, low-flow severe aortic stenosis with preserved left ventricular ejection fraction: characteristics, outcome, and implications for surgery J Am Coll Cardiol 65 2015 55 66
12. M.A. Clavel, D. Messika-Zeitoun, P. Pibarot, and et al. The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler-echocardiographic and computed tomographic study J Am Coll Cardiol 62 2013 2329 2338
13. M.K. Parmar, V. Torri, and L. Stewart Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints Stat Med 17 1998 2815 2834
14. H.C. Herrmann, P. Pibarot, I. Hueter, and et al. Predictors of mortality and outcomes of therapy in low flow severe aortic stenosis: a Placement of Aortic Transcatheter Valves (PARTNER) trial analysis Circulation 127 2013 2316 2326
15. E. Barasch, D. Fan, E.O. Chukwu, and et al. Severe isolated aortic stenosis with normal left ventricular systolic function and low transvalvular gradients: pathophysiologic and prognostic insights J Heart Valve Dis 17 2008 81 88
16. R.G. Pai, P. Varadarajan, and A. Razzouk Survival benefit of aortic valve replacement in patients with severe aortic stenosis with low ejection fraction and low gradient with normal ejection fraction Ann Thorac Surg 86 2008 1781 1789
17. R.N. Belkin, O. Khalique, W.S. Aronow, C. Ahn, and M. Sharma Outcomes and survival with aortic valve replacement compared with medical therapy in patients with low, moderate, and severe-gradient severe aortic stenosis and normal left ventricular ejection fraction Echocardiography 28 2011 378 387
18. G. Tarantini, E. Covolo, R. Razzolini, and et al. Valve replacement for severe aortic stenosis with low transvalvular gradient and left ventricular ejection fraction exceeding 0.50 Ann Thorac Surg 91 2011 1808 1815
19. P. Lancellotti, J. Magne, E. Donal, and et al. Clinical outcome in asymptomatic severe aortic stenosis. Insights from the new proposed aortic stenosis grading classification J Am Coll Cardiol 59 2012 235 243
20. D. Mohty, J. Magne, M. Deltreuil, and et al. Outcome and impact of surgery in paradoxical low-flow, low-gradient severe aortic stenosis and preserved left ventricular ejection fraction: a cardiac catheterization study Circulation 128 11 Suppl 1 2013 S235 S242
21. M.F. Eleid, P. Sorajja, H.I. Michelena, J.F. Malouf, C.G. Scott, and P.A. Pellikka Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival Circulation 128 2013 1781 1789
22. M.F. Eleid, P. Sorajja, H.I. Michelena, J.F. Malouf, C.G. Scott, and P.A. Pellikka Survival by stroke volume index in patients with low-gradient normal EF severe aortic stenosis Heart 101 2015 23 29
23. N. Jander, J. Minners, I. Holme, and et al. Outcome of patients with low-gradient "severe" aortic stenosis and preserved ejection fraction Circulation 123 2011 887 895
24. P. Pibarot, and J.G. Dumesnil Low-flow, low-gradient aortic stenosis with normal and depressed left ventricular ejection fraction J Am Coll Cardiol 60 2012 1845 1853
25. P. Pibarot, and J.G. Dumesnil Paradoxical low-flow, low-gradient aortic stenosis: new evidences, more questions Circulation 128 2013 1729 1732
26. J.G. Dumesnil, P. Pibarot, and B. Carabello Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment Eur Heart J 31 2010 281 289
27. M.A. Clavel, P.V. Ennezat, S. Maréchaux, and et al. Stress echocardiography to assess stenosis severity and predict outcome in patients with paradoxical low-flow, low-gradient aortic stenosis and preserved LVEF J Am Coll Cardiol Img 6 2013 175 183
28. M.A. Clavel, N. Coˆté, P. Mathieu, and et al. Paradoxical low-flow, low-gradient aortic stenosis despite preserved left ventricular ejection fraction: new insights from weights of operatively excised aortic valves Eur Heart J 35 2014 2655 2662
29. P. Pibarot, and J.G. Dumesnil Aortic stenosis suspected to be severe despite low gradients Circ Cardiovasc Imaging 7 2014 545 551
30. M.A. Clavel, M. Berthelot-Richer, V.F. Le, and et al. Impact of classic and paradoxical low flow on survival after aortic valve replacement for severe aortic stenosis J Am Coll Cardiol 65 2015 645 653
31. F. Le Ven, M. Freeman, J. Webb, and et al. Impact of low flow on the outcome of high-risk patients undergoing transcatheter aortic valve replacement J Am Coll Cardiol 62 2013 782 788
32. A. Grupper, R. Beigel, E. Maor, and et al. Survival after intervention in patients with low gradient severe aortic stenosis and preserved left ventricular function J Thorac Cardiovasc Surg 148 2014 2823 2827
33. C.J. O'Sullivan, S. Stortecky, D. Heg, and et al. Clinical outcomes of patients with low-flow, low-gradient, severe aortic stenosis and either preserved or reduced ejection fraction undergoing transcatheter aortic valve implantation Eur Heart J 34 2013 3437 3450
34. R. Parikh, A.L. Goodman, T. Barr, and et al. Outcomes of surgical aortic valve replacement for severe aortic stenosis: incorporation of left ventricular systolic function and stroke volume index J Thorac Cardiovasc Surg 149 2015 1558 1566
35. E. Yamashita, M. Takeuchi, Y. Seo, and et al. Prognostic value of paradoxical low-gradient severe aortic stenosis in Japan: Japanese Multicenter Aortic Stenosis Study, Retrospective (JUST-R) Registry J Cardiol 65 2015 360 368