Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony

Human Molecular Genetics

Volumn 25, Issue 7, 2016, Pages 1271-1280

  Vessoni, Alexandre T ^a,b   Herai, Roberto H ^a,c   Karpiak, Jerome V ^a   Leal, Angelica M S ^a,d   Trujillo, Cleber A ^a   Quinet, Annabel ^b   Agnez Lima, Lucymara F ^d   Menck, Carlos F M ^b   Muotri, Alysson R ^a  

^a RADY CHILDREN'S HOSPITAL   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; GROWTH HORMONE; MESSENGER RNA; MICRORNA; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; STAT5A PROTEIN; SYNAPSIN I; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA1; DNA HELICASE; DNA LIGASE; ERCC6 PROTEIN, HUMAN;

ACTION POTENTIAL; ADOLESCENT; ADULT; ARTICLE; BRAIN NERVE CELL; CELL CLONE; CELL DIFFERENTIATION; CELL MATURATION; COCKAYNE SYNDROME; CONTROLLED STUDY; EMBRYO; EMBRYOID BODY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LONG TERM POTENTIATION; MALE; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NEURAL STEM CELL; NEUROTRANSMISSION; NEXT GENERATION SEQUENCING; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SPIKE WAVE; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; TRANSCRIPTION REGULATION; CELL LINE; CHILD; DNA REPAIR; ELECTROPHYSIOLOGY; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MUTATION; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; CELL DIFFERENTIATION; CELL LINE; CHILD; CHILD, PRESCHOOL; COCKAYNE SYNDROME; DNA HELICASES; DNA REPAIR; DNA REPAIR ENZYMES; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; GROWTH HORMONE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INSULIN-LIKE GROWTH FACTOR I; MALE; MUTATION; NERVE NET; NEURONS; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84961399144     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw008     Document Type: Article

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